Bcl-x Promotes the Open Configuration of the Voltage-dependent Anion Channel and Metabolite Passage through the Outer Mitochondrial Membrane

Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c

Liu, X., Kim, C. N., Yang, J., Jemmerson, R., & Wang, X. (1996) · Cell · doi:10.1016/s0092-8674(00)80085-9 · Cited by 5,167 · see citing works

BCL-2 family members and the mitochondria in apoptosisPreprint

Gross, A., McDonnell, J. M., & Korsmeyer, S. J. (1999) · Genes & Development · doi:10.1101/gad.13.15.1899 · Cited by 3,623 · see citing works

Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

Shimizu, S., Narita, M., Tsujimoto, Y., & Tsujimoto, Y. (1999) · Nature · doi:10.1038/20959 · Cited by 2,178 · see citing works

Formation of Bimolecular Membranes from Lipid Monolayers and a Study of Their Electrical Properties

Montal, M., & Müeller, P. (1972) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.69.12.3561 · Cited by 1,811 · see citing works

Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c

Korsmeyer, S. J., Wei, M. C., Saito, M., Weiler, S., Oh, K. J., & Schlesinger, P. H. (2000) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4400783 · Cited by 1,034 · see citing works

Observations on the carbohydrate metabolism of tumours

Crabtree, H. G. (1929) · Biochemical Journal · doi:10.1042/bj0230536 · Cited by 864 · see citing works

Bcl-xL forms an ion channel in synthetic lipid membranes

Minn, A. J., Vélez, P., Schendel, S. L., Liang, H., Muchmore, S. W., Fesik, S. W., Fill, M., & Thompson, C. B. (1997) · Nature · doi:10.1038/385353a0 · Cited by 814 · see citing works

Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis?

Heiden, M. G. V., & Thompson, C. B. (1999) · Nature Cell Biology · doi:10.1038/70237 · Cited by 659 · see citing works

The role of the Bcl-2 family in the regulation of outer mitochondrial membrane permeability

Harris, M. H., & Thompson, C. B. (2000) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4400781 · Cited by 514 · see citing works

Bcl-xL Prevents Cell Death following Growth Factor Withdrawal by Facilitating Mitochondrial ATP/ADP Exchange

Heiden, M. G. V., Chandel, N. S., Schumacker, P. T., & Thompson, C. B. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80307-x · Cited by 505 · see citing works

Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival

Heiden, M. G. V., Chandel, N. S., Li, X. X., Schumacker, P. T., Colombini, M., & Thompson, C. B. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.090082297 · Cited by 444 · see citing works

The gramicidin a channel: A review of its permeability characteristics with special reference to the single-file aspect of transport

Finkelstein, A., & Andersen, O. S. (1981) · The Journal of Membrane Biology · doi:10.1007/bf01875422 · Cited by 373 · see citing works

CHARACTERISTICS OF ISOLATED AND PURIFIED PREPARATIONS OF THE OUTER AND INNER MEMBRANES OF MITOCHONDRIA*

Parsons, D. F., Williams, G. R., & Chance, B. (1966) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1966.tb50188.x · Cited by 362 · see citing works

VDAC regulation by the Bcl-2 family of proteins

Tsujimoto, Y., & Shimizu, S. (2000) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4400780 · Cited by 338 · see citing works

Bcl-xL Prevents the Initial Decrease in Mitochondrial Membrane Potential and Subsequent Reactive Oxygen Species Production during Tumor Necrosis Factor Alpha-Induced Apoptosis

Gottlieb, E., Heiden, M. G. V., & Thompson, C. B. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.15.5680-5689.2000 · Cited by 317 · see citing works

Voltage gating in the mitochondrial channel, VDAC

Colombini, M. (1989) · The Journal of Membrane Biology · doi:10.1007/bf01871775 · Cited by 307 · see citing works

Regulation of Metabolite Flux through Voltage-Gating of VDAC Channels

Hodge, T., & Colombini, M. (1997) · The Journal of Membrane Biology · doi:10.1007/s002329900235 · Cited by 281 · see citing works

Selectivity Changes in Site-Directed Mutants of the VDAC Ion Channel: Structural Implications

Blachly‐Dyson, E., Peng, S., Colombini, M., & Forte, M. A. (1990) · Science · doi:10.1126/science.1690454 · Cited by 273 · see citing works

Mitochondrial outer membrane contains a protein producing nonspecific diffusion channels.

Zalman, L. S., Nikaido, H., & Kagawa, Y. (1980) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)85942-2 · Cited by 220 · see citing works

NADH regulates the gating of VDAC, the mitochondrial outer membrane channel.

Zizi, M., Forte, M. A., Blachly‐Dyson, E., & Colombini, M. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)42070-9 · Cited by 205 · see citing works

Porin interaction with hexokinase and glycerol kinase: Metabolic microcompartmentation at the outer mitochondrial membrane

Adams, V., Griffin, L., Towbin, J. A., Gelb, B. D., Worley, K. C., & McCabe, E. R. B. (1991) · Biochemical Medicine and Metabolic Biology · doi:10.1016/0885-4505(91)90032-g · Cited by 139 · see citing works

Pore size and properties of channels from mitochondria isolated fromNeurospora crassa

Colombini, M. (1980) · The Journal of Membrane Biology · doi:10.1007/bf01870576 · Cited by 136 · see citing works

Beta-NADH decreases the permeability of the mitochondrial outer membrane to ADP by a factor of 6.

Lee, A.-R. C., Zizi, M., & Colombini, M. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)47377-2 · Cited by 127 · see citing works

Inhibition of adenine nucleotide transport through the mitochondrial porin by a synthetic polyanion

Benz, R., Wojtczak, L., Bosch, W., & Brdiczka, D. G. (1988) · FEBS Letters · doi:10.1016/0014-5793(88)80706-3 · Cited by 121 · see citing works

Regulation of mitochondrial respiration by controlling the permeability of the outer membrane through the mitochondrial channel, VDAC

Liu, M. Y., & Colombini, M. (1992) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(05)80344-5 · Cited by 109 · see citing works

The ‘ins’ and ‘outs’ of mitochondrial membrane channels

Mannella, C. A. (1992) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(92)90444-e · Cited by 99 · see citing works

The Sensor Regions of VDAC Are Translocated from within the Membrane to the Surface during the Gating Processes

Song, J., Midson, C. N., Blachly‐Dyson, E., Forte, M. A., & Colombini, M. (1998) · Biophysical Journal · doi:10.1016/s0006-3495(98)78000-2 · Cited by 99 · see citing works

Effect of macromolecules on the regulation of the mitochondrial outer membrane pore and the activity of adenylate kinase in the inter-membrane space

Gellerich, F. N., Wagner, M., Kapischke, M., Wicker, U., & Brdiczka, D. G. (1993) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/0005-2728(93)90150-e · Cited by 71 · see citing works

[43] Characterization of channels isolated from plant mitochondria

Colombini, M. (1987) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(87)48045-2 · Cited by 57 · see citing works

Regulation of Bcl-xl Channel Activity by Calcium

Lam, M. C., Bhat, M. B., Núñez, G., et al. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.28.17307 · Cited by 49 · see citing works

Metabolically Derived Potential on the Outer Membrane of Mitochondria: A Computational Model

Lemeshko, S. V., & Lemeshko, V. V. (2000) · Biophysical Journal · doi:10.1016/s0006-3495(00)76518-0 · Cited by 37 · see citing works

[27] Isolation and properties of the porin of the outer mitochondrial membrane from Neurospora crassa

Freitag, H., Benz, R., & Neupert, W. (1983) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(83)97140-9 · Cited by 31 · see citing works

An unique method for determining the permeability of the mitochondrial outer membrane

Lee, A.-C., & Colombini, M. (1997) · Methods in Cell Science · doi:10.1023/a:1009761922055 · Cited by 5 · see citing works

Molecular mechanisms of cell death: recommendations of the nomenclature committee on cell death 2018.

Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., et al. (2018) · Cell Death & Differentiation · doi:10.1038/s41418-017-0012-4 · Cited by 6,680 · see citing works

Mitochondrial membrane permeabilization in cell death

Kroemer, G., Galluzzi, L., & Brenner, C. (2007) · Physiological Reviews · doi:10.1152/physrev.00013.2006 · Cited by 3,598 · see citing works

Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death

Baines, C. P., Kaiser, R. A., Sheiko, T., Craigen, W. J., & Molkentin, J. D. (2007) · Nature Cell Biology · doi:10.1038/ncb1575 · Cited by 971 · see citing works

VDAC2 Inhibits BAK Activation and Mitochondrial Apoptosis

Cheng, E. H.-Y., Sheiko, T. V., Fisher, J. K., Craigen, W. J., & Korsmeyer, S. J. (2003) · Science · doi:10.1126/science.1083995 · Cited by 852 · see citing works

Solution structure of the integral human membrane protein VDAC-1 in detergent micelles

Hiller, S., Garces, R. G., Malia, T. J., Orekhov, V. Y., Colombini, M., & Wagner, G. (2008) · Science · doi:10.1126/science.1161302 · Cited by 667 · see citing works

Mitochondrial outer membrane permeabilization during apoptosis: the innocent bystander scenario

Chipuk, J. E., Bouchier-Hayes, L., & Green, D. R. (2006) · Cell Death & Differentiation · doi:10.1038/sj.cdd.4401963 · Cited by 631 · see citing works

Mitochondrial Permeability Transition: New Findings and Persisting Uncertainties

Izzo, V., Bravo-San Pedro, J. M., Sica, V., Kroemer, G., & Galluzzi, L. (2016) · Trends in Cell Biology · doi:10.1016/j.tcb.2016.04.006 · Cited by 205 · see citing works

VDAC1 at the crossroads of cell metabolism, apoptosis and cell stress

Shoshan-Barmatz, V., N. Maldonado, E., & Krelin, Y. (2017) · Cell Stress · doi:10.15698/cst2017.10.104 · Cited by 170 · see citing works

Identification of the protein-protein contact site and interaction mode of human VDAC1 with Bcl-2 family proteins

Shi, Y., Chen, J., Weng, C., Chen, R., Zheng, Y., Chen, Q., & Tang, H. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(03)00871-4 · Cited by 158 · see citing works

Bcl-2 family in inter-organelle modulation of calcium signaling; roles in bioenergetics and cell survival

Lewis, A., Hayashi, T., Su, T.-P., & Betenbaugh, M. J. (2014) · Journal of Bioenergetics and Biomembranes · doi:10.1007/s10863-013-9527-7 · Cited by 66 · see citing works

Origami in the outer membrane: the transmembrane arrangement of mitochondrial porins

Bay, D. C., & Court, D. A. (2002) · Biochemistry and Cell Biology · doi:10.1139/o02-149 · Cited by 35 · see citing works

The Mitochondrial Porin, VDAC, Has Retained the Ability to Be Assembled in the Bacterial Outer Membrane

Walther, D. M., Bos, M. P., Rapaport, D., & Tommassen, J. (2009) · Molecular Biology and Evolution · doi:10.1093/molbev/msp294 · Cited by 49 · see citing works

Improved methods to isolate and subfractionate rat liver mitochondria. Lipid composition of the inner and outer membrane

Hovius, R., Lambrechts, H. A. J., Nicolay, K., & KRUIJFF, B. D. (1990) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(90)90036-n · Cited by 353 · see citing works

Molecular basis of morphological changes in mitochondrial membrane accompanying induction of permeability transition, as revealed by immuno-electron microscopy

Terauchi, S., Yamamoto, T., Yamashita, K., Kataoka, M., Terada, H., & Shinohara, Y. (2005) · Mitochondrion · doi:10.1016/j.mito.2005.04.002 · Cited by 11 · see citing works

Mitochondrial and plasma membrane potentials cause unusual accumulation and retention of rhodamine 123 by human breast adenocarcinoma-derived MCF-7 cells.

Davis, S., Weiss, M. J., Wong, J. R., Lampidis, T. J., & Chen, L. B. (1985) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)38802-6 · Cited by 401 · see citing works