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Disrupted Bile Acid Homeostasis Reveals an Unexpected Interaction among Nuclear Hormone Receptors, Transporters, and Cytochrome P450
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ABCC4 is expressed in various tissues, including liver, brain, kidney, colon, lung and placenta.
“ABCC4, the top-ranking putative negative regulator of LDLR identified in our screens, is expressed in various tissues, including the liver, brain, kidney, colon, lung and placenta38,39.”
From ABCC4 impairs the clearance of plasma LDL cholesterol through suppressing LDLR expression in the liver (2025) · cites this paper as [38]
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Metadata
- Authors
- Schuetz, E. G., Strom, S., Yasuda, K., Lecureur, V., Assem, M., Brimer, C., Lamba, J., Kim, R. B., Ramachandran, V., Komoroski, B. J., Venkataramanan, R., Cai, H., Sinal, C. J., Gonzalez, F. J., & Schuetz, J. D.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 2001-10
- Volume
- 276
- Issue
- 42
- Pages
- 39411-39418
- ISSN
- 0021-9258
- Cited by
- 334
- References
- 1
- Language
- en
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