Cited by 35

The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.

Di-retinoid-pyridinium-ethanolamine (A2E) Accumulation and the Maintenance of the Visual Cycle Are Independent of Atg7-mediated Autophagy in the Retinal Pigmented Epithelium

Perusek, Lindsay, Sahu, Bhubanananda, Parmar, Tanu, Maeno, Hiroshi, Arai, Eisuke, Le, Yun-Zheng, Subauste, Carlos S., Chen, Yu, Palczewski, Krzysztof, Maeda, Akiko·2015·Journal of Biological Chemistry

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1074/jbc.m115.682310

Cites

16 of 16 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 45

  1. Strauss, 2005, The retinal pigment epithelium in visual function, Physiol. Rev, 85, 845, 10.1152/physrev.00021.2004 · DOI · Paper page
  2. Duncan, 2003, An RCS-like retinal dystrophy phenotype in mer knockout mice, Invest. Ophthalmol. Vis. Sci, 44, 826, 10.1167/iovs.02-0438 · DOI
  3. Mizushima, 2011, Autophagy: renovation of cells and tissues, Cell, 147, 728, 10.1016/j.cell.2011.10.026 · DOI
  4. Komatsu, 2005, Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice, J. Cell Biol, 169, 425, 10.1083/jcb.200412022 · DOI · Paper page
  5. Komatsu, 2007, Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice, Cell, 131, 1149, 10.1016/j.cell.2007.10.035 · DOI · Paper page
  6. Hara, 2006, Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice, Nature, 441, 885, 10.1038/nature04724 · DOI · Paper page
  7. Vives-Bauza, 2010, PINK1-dependent recruitment of Parkin to mitochondria in mitophagy, Proc. Natl. Acad. Sci. U.S.A, 107, 378, 10.1073/pnas.0911187107 · DOI · Paper page
  8. Jo, 2014, Nrf2 reduces levels of phosphorylated tau protein by inducing autophagy adaptor protein NDP52, Nat. Commun, 5, 3496, 10.1038/ncomms4496 · DOI · Paper page
  9. Klionsky, 2003, A unified nomenclature for yeast autophagy-related genes, Dev. Cell, 5, 539, 10.1016/S1534-5807(03)00296-X · DOI
  10. Noda, 2011, Structural basis of Atg8 activation by a homodimeric E1, Atg7, Mol. Cell, 44, 462, 10.1016/j.molcel.2011.08.035 · DOI
  11. Kunchithapautham, 2007, Apoptosis and autophagy in photoreceptors exposed to oxidative stress, Autophagy, 3, 433, 10.4161/auto.4294 · DOI
  12. Besirli, 2011, Autophagy activation in the injured photoreceptor inhibits fas-mediated apoptosis, Invest. Ophthalmol. Vis. Sci, 52, 4193, 10.1167/iovs.10-7090 · DOI
  13. Saadat, 2014, Inhibition of autophagy induces retinal pigment epithelial cell damage by the lipofuscin fluorophore A2E, FEBS, 4, 1007
  14. Lee, 2014, Retinal pigment epithelial cells undergoing mitotic catastrophe are vulnerable to autophagy inhibition, Cell Death Dis, 5, e1303, 10.1038/cddis.2014.266 · DOI
  15. Yao, 2014, Circadian and noncircadian modulation of autophagy in photoreceptors and retinal pigment epithelium, Invest. Ophthalmol. Vis. Sci, 55, 3237, 10.1167/iovs.13-13336 · DOI · Paper page
  16. Birnbach, 1994, Histopathology and immunocytochemistry of the neurosensory retina in fundus flavimaculatus, Ophthalmology, 101, 1211, 10.1016/S0161-6420(13)31725-4 · DOI
  17. Zhou, 2006, Complement activation by photooxidation products of A2E, a lipofuscin constituent of the retinal pigment epithelium, Proc. Natl. Acad. Sci. U.S.A, 103, 16182, 10.1073/pnas.0604255103 · DOI · Paper page
  18. Illing, 1997, The 220-kDa Rim protein of retinal rod outer segments is a member of the ABC transporter superfamily, J. Biol. Chem, 272, 10303, 10.1074/jbc.272.15.10303 · DOI
  19. Molday, 2007, ATP-binding cassette transporter ABCA4: molecular properties and role in vision and macular degeneration, J. Bioenerg. Biomembr, 39, 507, 10.1007/s10863-007-9118-6 · DOI
  20. Eldred, 1993, Retinal age pigments generated by self-assembling lysosomotropic detergents, Nature, 361, 724, 10.1038/361724a0 · DOI
  21. Sparrow, 1999, A2E, a lipofuscin fluorophore, in human retinal pigmented epithelial cells in culture, Invest. Ophthalmol. Vis. Sci, 40, 2988
  22. Holz, 1999, Inhibition of lysosomal degradative functions in RPE cells by a retinoid component of lipofuscin, Invest. Ophthalmol. Vis. Sci, 40, 737
  23. Schütt, 2000, Photodamage to human RPE cells by A2-E, a retinoid component of lipofuscin, Invest. Ophthalmol. Vis. Sci, 41, 2303
  24. Maeda, 2008, Retinopathy in mice induced by disrupted all-trans-retinal clearance, J. Biol. Chem, 283, 26684, 10.1074/jbc.M804505200 · DOI · Paper page
  25. Kohno, 2013, Photoreceptor proteins initiate microglial activation via Toll-like receptor 4 in retinal degeneration mediated by all-trans-retinal, J. Biol. Chem, 288, 15326, 10.1074/jbc.M112.448712 · DOI
  26. Maeda, 2005, Role of photoreceptor-specific retinol dehydrogenase in the retinoid cycle in vivo, J. Biol. Chem, 280, 18822, 10.1074/jbc.M501757200 · DOI · Paper page
  27. Diemer, 2008, Analysis of the rate of disk membrane digestion by cultured RPE cells, Adv. Exp. Med. Biol, 613, 321, 10.1007/978-0-387-74904-4_37 · DOI
  28. Maeda, 2013, Retinal pigmented epithelial cells obtained from human induced pluripotent stem cells possess functional visual cycle enzymes in vitro and in vivo, J. Biol. Chem, 288, 34484, 10.1074/jbc.M113.518571 · DOI
  29. Osakada, 2009, Stepwise differentiation of pluripotent stem cells into retinal cells, Nat. Protoc, 4, 811, 10.1038/nprot.2009.51 · DOI
  30. Iriyama, 2008, A2E, a pigment of the lipofuscin of retinal pigment epithelial cells, is an endogenous ligand for retinoic acid receptor, J. Biol. Chem, 283, 11947, 10.1074/jbc.M708989200 · DOI
  31. Bjorkoy, 2005, p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death, J. Cell Biol, 171, 603, 10.1083/jcb.200507002 · DOI · Paper page
  32. Guha, 2014, Rescue of compromised lysosomes enhances degradation of photoreceptor outer segments and reduces lipofuscin-like autofluorescence in retinal pigmented epithelial cells, Adv. Exp. Med. Biol, 801, 105, 10.1007/978-1-4614-3209-8_14 · DOI
  33. Holz, 1999, [Introduction of the lipofuscin-fluorophor A2E into the lysosomal compartment of human retinal pigment epithelial cells by coupling to LDL particles. An in vitro model of retinal pigment epithelium cell aging], Ophthalmologe, 96, 781, 10.1007/s003470050496 · DOI
  34. Radu, 2011, Complement system dysregulation and inflammation in the retinal pigment epithelium of a mouse model for Stargardt macular degeneration, J. Biol. Chem, 286, 18593, 10.1074/jbc.M110.191866 · DOI · Paper page
  35. Wenzel, 2001, The Rpe65 Leu450Met variation increases retinal resistance against light-induced degeneration by slowing rhodopsin regeneration, J. Neurosci, 21, 53, 10.1523/JNEUROSCI.21-01-00053.2001 · DOI
  36. Wu, 2014, Caspases: a molecular switch node in the crosstalk between autophagy and apoptosis, Int. J. Biol. Sci, 10, 1072, 10.7150/ijbs.9719 · DOI
  37. Basu, 2014, Suppression of MAPK/JNK-MTORC1 signaling leads to premature loss of organelles and nuclei by autophagy during terminal differentiation of lens fiber cells, Autophagy, 10, 1193, 10.4161/auto.28768 · DOI
  38. Kaushik, 2008, Constitutive activation of chaperone-mediated autophagy in cells with impaired macroautophagy, Mol. Biol. Cell, 19, 2179, 10.1091/mbc.e07-11-1155 · DOI
  39. Massey, 2006, Consequences of the selective blockage of chaperone-mediated autophagy, Proc. Natl. Acad. Sci. U.S.A, 103, 5805, 10.1073/pnas.0507436103 · DOI · Paper page
  40. Nishida, 2009, Discovery of Atg5/Atg7-independent alternative macroautophagy, Nature, 461, 654, 10.1038/nature08455 · DOI · Paper page
  41. Mata, 2000, Biosynthesis of a major lipofuscin fluorophore in mice and humans with ABCR-mediated retinal and macular degeneration, Proc. Natl. Acad. Sci. U.S.A, 97, 7154, 10.1073/pnas.130110497 · DOI · Paper page
  42. Yannuzzi, 2004, Ophthalmic fundus imaging: today and beyond, Am. J. Ophthalmol, 137, 511, 10.1016/j.ajo.2003.12.035 · DOI
  43. Toops, 2015, Cholesterol-mediated activation of acid sphingomyelinase disrupts autophagy in the retinal pigment epithelium, Mol. Biol. Cell, 26, 1, 10.1091/mbc.e14-05-1028 · DOI · Paper page
  44. Lakkaraju, 2007, The lipofuscin fluorophore A2E perturbs cholesterol metabolism in retinal pigment epithelial cells, Proc. Natl. Acad. Sci. U.S.A, 104, 11026, 10.1073/pnas.0702504104 · DOI · Paper page
  45. Mitter, 2014, Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD, Autophagy, 10, 1989, 10.4161/auto.36184 · DOI · Paper page

Cited by

Sorted by citations

Metadata

Authors
Perusek, L., Sahu, B., Parmar, T., Maeno, H., Arai, E., Le, Y.-Z., Subauste, C. S., Chen, Y., Palczewski, K., & Maeda, A.
Venue
Journal of Biological Chemistry
Publisher
Elsevier BV
Published
2015-11
Volume
290
Issue
48
Pages
29035-29044
ISSN
0021-9258
Cited by
35
References
16
Language
en

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review