Homologues of Human Macrophage Migration Inhibitory Factor from a Parasitic Nematode

Zang, Xingxing; Taylor, Paul; Wang, Ji Ming; Meyer, David J.; Scott, Alan L.; Walkinshaw, Malcolm D.; Maizels, Rick M.

doi:10.1074/jbc.m204655200

Cited by 109Macrophage Migration Inhibitory FactorParasites and Host InteractionsParasitic Diseases Research and Treatment

The DOI matches its Crossref record, with a small difference in title or year; 57 of the 58 references it cites were found in a registry or an index.

Homologues of Human Macrophage Migration Inhibitory Factor from a Parasitic Nematode

Open access

Zang, Xingxing, Taylor, Paul, Wang, Ji Ming, Meyer, David J., Scott, Alan L., Walkinshaw, Malcolm D., Maizels, Rick M.·2002·Journal of Biological Chemistry

DOI 10.1074/jbc.m204655200

Open this paper in CoChat — free account Open PDF

Abstract

Cytokines are the molecular messengers of the vertebrate immune system, coordinating the local and systemic immune responses to infective organisms. We report here functional and structural data on cytokine-like proteins from a eukaryotic pathogen. Two homologues of the human cytokine macrophage migration inhibitory factor (MIF) have been isolated from the parasitic nematode Brugia malayi. Both molecules (Bm-MIF-1 and Bm-MIF-2) show parallel functions to human MIF. They are chemotactic for human monocytes and activate them to produce IL-8, TNF-alpha, and endogenous MIF. The human and nematode MIF homologues share a tautomerase enzyme activity, which is in each case abolished by the mutation of the N-terminal proline residue. The crystal structure of Bm-MIF-2 at 1.8-A resolution has been determined, revealing a trimeric assembly with an inner pore created by beta-stranded sheets from each subunit. Both biological activity and crystal structure reveal remarkable conservation between a human cytokine and its parasite counterpart despite the considerable phylogenetic divide among these organisms. The strength of the similarity implies that MIF-mediated pathways play an important role in nematode immune evasion strategies.

Integrity signals

Registry

Crossref · 10.1074/jbc.m204655200

Cites

57 of 57 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

B. malayi and T. spiralis MIF mirror the activity of host MIF, inducing IL-8 release from monocytes.
“those from Brugia malayi (Zang et al., 2002) and Trichinella spiralis (Tan et al., 2001) mirror the activity of the host protein, inducing IL-8 release from monocytes”
From Modulation of Host Immunity by Helminths: The Expanding Repertoire of Parasite Effector Molecules (2018) · cites this paper as Zang et al., 2002

[20] Processing of X-ray diffraction data collected in oscillation mode
Otwinowski, Z., & Minor, W. (1997) · Methods in Enzymology · doi:10.1016/s0076-6879(97)76066-x · Cited by 33,475
Automated MAD and MIR structure solution
Terwilliger, T. C., & Berendzen, J. (1999) · Acta Crystallographica Section D Biological Crystallography · doi:10.1107/s0907444999000839 · Cited by 3,038
Mechanism of a Reaction in Vitro Associated with Delayed-Type Hypersensitivity
Bloom, B. R., & Bennett, B. P. (1966) · Science · doi:10.1126/science.153.3731.80 · Cited by 1,605
Delayed hypersensitivity in vitro: its mediation by cell-free substances formed by lymphoid cell-antigen interaction.
David, J. R. (1966) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.56.1.72 · Cited by 1,272
MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia
Bernhagen, J., Calandra, T., Mitchell, R. A., Martin, S. B., Tracey, K. J., Voelter, W., Manogue, K. R., Cerami, A., & Bucala, R. (1993) · Nature · doi:10.1038/365756a0 · Cited by 1,001
Viral Strategies of Immune Evasion
Ploegh, H. L. (1998) · Science · doi:10.1126/science.280.5361.248 · Cited by 786
Protection from septic shock by neutralization of macrophage migration inhibitory factor
Calandra, T., Echtenacher, B., Roy, D. L., Pugin, J., Metz, C. N., Hültner, L., Heumann, D., Männel, D. N., Bucala, R., & Glauser, M. P. (2000) · Nature Medicine · doi:10.1038/72262 · Cited by 724
Other Functions, Other Genes
Goerdt, S., & Orfanos, C. E. (1999) · Immunity · doi:10.1016/s1074-7613(00)80014-x · Cited by 678
MIF regulates innate immune responses through modulation of Toll-like receptor 4
Roger, T., David, J. R., Glauser, M. P., & Calandra, T. (2001) · Nature · doi:10.1038/414920a · Cited by 586
Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1
Kleemann, R., Haußer, A., Geiger, G., Mischke, R., Burger‐Kentischer, A., Flieger, O., Johannes, F., Roger, T., Calandra, T., Kapurniotu, A., et al. (2000) · Nature · doi:10.1038/35041591 · Cited by 567
Viral mechanisms of immune evasion
Alcamı́, A., & Koszinowski, U. H. (2000) · Immunology Today · doi:10.1016/s0167-5699(00)01699-6 · Cited by 556
Targeted Disruption of Migration Inhibitory Factor Gene Reveals Its Critical Role in Sepsis
Bozza, M. T., Satoskar, A. R., Lin, G., Lu, B., Humbles, A. A., Gerard, C. J., & David, J. R. (1999) · The Journal of Experimental Medicine · doi:10.1084/jem.189.2.341 · Cited by 551
Immunological modulation and evasion by helminth parasites in human populations
Maizels, R. M., Bundy, D. A. P., Selkirk, M. E., Smith, D. F., & Anderson, R. M. (1993) · Nature · doi:10.1038/365797a0 · Cited by 529
Self-citation
Re-assessing the global prevalence and distribution of lymphatic filariasis
Michael, E., Bundy, D. A. P., & Grenfell, B. T. (1996) · Parasitology · doi:10.1017/s0031182000066646 · Cited by 516
Molecular Evidence for Deep Precambrian Divergences Among Metazoan Phyla
Wray, G. A., Levinton, J. S., & Shapiro, L. H. (1996) · Science · doi:10.1126/science.274.5287.568 · Cited by 511
Regulatory role for macrophage migration inhibitory factor in acute respiratory distress syndrome
Donnelly, S. C., Haslett, C., Reid, P. T., Grant, I. S., Wallace, W. A., Metz, C. N., Bruce, L. J., & Bucala, R. (1997) · Nature Medicine · doi:10.1038/nm0397-320 · Cited by 448
A Seven-transmembrane, G Protein–coupled Receptor, FPRL1, Mediates the Chemotactic Activity of Serum Amyloid A for Human Phagocytic Cells
Su, S. B., Gong, W., Gao, J., Shen, W., Murphy, P. M., Oppenheim, J. J., & Wang, J. (1999) · The Journal of Experimental Medicine · doi:10.1084/jem.189.2.395 · Cited by 430
Self-citation
Molecular cloning of a cDNA encoding a human macrophage migration inhibitory factor.
Weiser, W. Y., Temple, P. A., Witek-Giannotti, J. S., Remold, H., Clark, S., & David, J. R. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.19.7522 · Cited by 341
Crystal structure at 2.6-A resolution of human macrophage migration inhibitory factor.
Sun, H., Bernhagen, J., Bucala, R., & Lolis, E. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.11.5191 · Cited by 337
Removal of Endotoxin from Recombinant Protein Preparations
Liu, S., Tobias, R. B., McClure, S., Styba, G., Shi, Q., & Jackowski, G. (1997) · Clinical Biochemistry · doi:10.1016/s0009-9120(97)00049-0 · Cited by 332
Development of chronic colitis is dependent on the cytokine MIF
de Jong, Y. P., Abadía‐Molina, A. C., Satoskar, A. R., Clarke, K., Rietdijk, S. T., Faubion, W. A., Mizoguchi, E., Metz, C. N., Sahli, M. A., ten Hove, T., et al. (2001) · Nature Immunology · doi:10.1038/ni720 · Cited by 305
Cytokine control of parasite-specific anergy in human lymphatic filariasis. Preferential induction of a regulatory T helper type 2 lymphocyte subset.
King, C. L., Mahanty, S., Kumaraswami, V., Abrams, J. S., Regunathan, J., Jayaraman, K., Ottesen, E. A., & Nutman, T. B. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116752 · Cited by 292
The macrophage migration inhibitory factor MIF is a phenylpyruvate tautomerase
Rosengren, E., Åman, P., Thelin, S., Hansson, C., Ahlfors, S., Björk, P., Jacobsson, L., & Rorsman, H. (1997) · FEBS Letters · doi:10.1016/s0014-5793(97)01261-1 · Cited by 259
Filarial Nematode Parasites Secrete a Homologue of the Human Cytokine Macrophage Migration Inhibitory Factor
Pastrana, D., Raghavan, N., Fitzgerald, P., Eisinger, S. W., Metz, C., Bucala, R., Schleimer, R., Bickel, C., & Scott, A. L. (1998) · Infection and Immunity · doi:10.1128/iai.66.12.5955-5963.1998 · Cited by 253
Self-citation
Bm-CPI-2, a cystatin homolog secreted by the filarial parasite Brugia malayi, inhibits class II MHC-restricted antigen processing
Manoury, B., Gregory, W. F., Maizels, R. M., & Watts, C. (2001) · Current Biology · doi:10.1016/s0960-9822(01)00118-x · Cited by 223
Self-citation
Direct link between cytokine activity and a catalytic site for macrophage migration inhibitory factor
Swope, M., Sun, H., Blake, P. R., & Lolis, E. (1998) · The EMBO Journal · doi:10.1093/emboj/17.13.3534 · Cited by 205
Crystal structure of the macrophage migration inhibitory factor from rat liver
Suzuki, M., Sugimoto, H., Nakagawa, A., Tanaka, I., Nishihira, J., & Sakai, M. (1996) · Nature Structural Biology · doi:10.1038/nsb0396-259 · Cited by 192
Immunological tolerance: The key feature in human filariasis?
Maizels, R. M., & Lawrence, R. A. (1991) · Parasitology Today · doi:10.1016/0169-4758(91)90093-4 · Cited by 189
Self-citation
Tumor growth-promoting properties of macrophage migration inhibitory factor (MIF)
Mitchell, R. A., & Bucala, R. (2000) · Seminars in Cancer Biology · doi:10.1006/scbi.2000.0328 · Cited by 176
Immune evasion genes from filarial nematodes
Maizels, R. M., Gomez‐Escobar, N., Gregory, W. F., Murray, J., & Zang, X. (2001) · International Journal for Parasitology · doi:10.1016/s0020-7519(01)00213-2 · Cited by 168
Self-citation
Pro-1 of Macrophage Migration Inhibitory Factor Functions as a Catalytic Base in the Phenylpyruvate Tautomerase Activity,
Lubetsky, J. B., Swope, M. D., Dealwis, C. G., Blake, P. R., & Lolis, E. (1999) · Biochemistry · doi:10.1021/bi990306m · Cited by 166
Identification of tgh-2, a Filarial Nematode Homolog of Caenorhabditis elegans daf-7 and Human Transforming Growth Factor β, Expressed in Microfilarial and Adult Stages of Brugia malayi
Gomez-Escobar, N., Gregory, W. F., & Maizels, R. M. (2000) · Infection and Immunity · doi:10.1128/iai.68.11.6402-6410.2000 · Cited by 162
Self-citation
A Brugia malayi Homolog of Macrophage Migration Inhibitory Factor Reveals an Important Link Between Macrophages and Eosinophil Recruitment During Nematode Infection1
Falcone, F. H., Loke, P., Zang, X.-X., MacDonald, A., Maizels, R., & Allen, J. (2001) · Journal of Immunology · doi:10.4049/jimmunol.167.9.5348 · Cited by 160
Self-citation
Modulation of Human T Cell Responses and Macrophage Functions by Onchocystatin, a Secreted Protein of the Filarial Nematode Onchocerca volvulus
Schönemeyer, A., Lucius, R., Sonnenburg, B., Brattig, N., Sabat, R., Schilling, K., Bradley, J., & Hartmann, S. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.167.6.3207 · Cited by 155
T-cell activation and the balance of antibody isotypes in human lymphatic filariasis
Maizels, R. M., Sartono, E., Kurniawan, A., Partono, F., Selkirk, M. E., & Yazdanbakhsh, M. (1995) · Parasitology Today · doi:10.1016/0169-4758(95)80116-2 · Cited by 154
Self-citation
Serine proteinase inhibitors from nematodes and the arms race between host and pathogen
Zang, X., & Maizels, R. M. (2001) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(00)01761-8 · Cited by 149
Self-citation
A Novel Serpin Expressed by Blood-Borne Microfilariae of the Parasitic Nematode Brugia malayi Inhibits Human Neutrophil Serine Proteinases
Zang, X., Yazdanbakhsh, M., Jiang, H., Kanost, M. R., & Maizels, R. M. (1999) · Blood · doi:10.1182/blood.v94.4.1418 · Cited by 121
Self-citation
Do Antioxidants Play a Role in Schistosome Host–Parasite Interactions?
LoVerde, P. T. (1998) · Parasitology Today · doi:10.1016/s0169-4758(98)01261-7 · Cited by 102
The filarial genome project: analysis of the nuclear, mitochondrial and endosymbiont genomes of Brugia malayi
Williams, S. A., Lizotte‐Waniewski, M., Foster, J. M., Guiliano, D. B., Daub, J., Scott, A. L., Slatko, B. E., & Blaxter, M. (2000) · International Journal for Parasitology · doi:10.1016/s0020-7519(00)00014-x · Cited by 93
Self-citation
Role of Macrophage Migration Inhibitory Factor in the Regulation of the Immune Response
Metz, C. N., & Bucala, R. (1997) · Advances in immunology · doi:10.1016/s0065-2776(08)60598-2 · Cited by 91
Enzyme Activity of Macrophage Migration Inhibitory Factor toward Oxidized Catecholamines
Matsunaga, J., Sinha, D., Pannell, L., Santis, C., Solano, F., Wistow, G. J., & Hearing, V. J. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.6.3268 · Cited by 85
A most interesting factor
Bucala, R. (2000) · Nature · doi:10.1038/35041654 · Cited by 77
Differentially expressed, abundant trans-spliced cDNAs from larval Brugia malayi1Note: Nucleotide sequence data reported in this paper are available in the EMBL, GenBank™ and DDJB databases under the accession numbers U57547, U80971-U80980, U81008 and U84736.1
Gregory, W. F., Blaxter, M., & Maizels, R. M. (1997) · Molecular and Biochemical Parasitology · doi:10.1016/s0166-6851(97)00050-9 · Cited by 77
Self-citation
Crystal Structure of Macrophage Migration Inhibitory Factor Complexed with ( E )-2-Fluoro- p -hydroxycinnamate at 1.8 Å Resolution: Implications for Enzymatic Catalysis and Inhibition ,
Taylor, A. B., Johnson, W. H., Czerwiński, R., Li, H.-S., Hackert, M. L., & Whitman, C. P. (1999) · Biochemistry · doi:10.1021/bi9904048 · Cited by 73
The Serpin Secreted by Brugia malayi Microfilariae, Bm-SPN-2, Elicits Strong, but Short-Lived, Immune Responses in Mice and Humans
Zang, X., Kurniawan, A., Gray, P. E., Allen, J. E., Gray, C. A., Lawrence, R. A., Yazdanbakhsh, M., & Maizels, R. M. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.165.9.5161 · Cited by 68
Self-citation
Parasitic helminth genomics
Blaxter, M., Aslett, M. A., Guiliano, D. B., Daub, J., & THE FILARIAL GENOME PROJECT (1999) · Parasitology · doi:10.1017/s0031182099004060 · Cited by 51
Macrophage migration inhibitory factor of the parasitic nematode Trichinella spiralis
TAN, T. H. P., EDGERTON, S. A. V., KUMARI, R., McALISTER, M. S. B., ROWE, S. M., NAGL, S., PEARL, L. H., SELKIRK, M. E., BIANCO, A. E., TOTTY, N. F., et al. (2001) · Biochemical Journal · doi:10.1042/bj3570373 · Cited by 50
Self-citation
Macrophage migration inhibitory factor (mif) transcription is significantly elevated in Caenorhabditis elegans dauer larvae
Marson, A. L., Tarr, D. E. K., & Scott, A. L. (2001) · Gene · doi:10.1016/s0378-1119(01)00706-5 · Cited by 50
Self-citation
Lymphatic filariasis: What mice can tell us
Lawrence, R. A. (1996) · Parasitology Today · doi:10.1016/0169-4758(96)10025-9 · Cited by 43
Purification of macrophage migration inhibitory factor (MIF) from bovine brain cytosol
Gałat, A., Riviere, S., & Bouet, F. (1993) · FEBS Letters · doi:10.1016/0014-5793(93)80553-7 · Cited by 36
The filarial genome project
Unnasch, T. R. (1994) · Parasitology Today · doi:10.1016/0169-4758(94)90168-6 · Cited by 32
Mitogen-activated kinase kinase kinase 1 regulates T cell receptor- and CD28-mediated signaling events which lead to NF-κB activation
Tuosto, L., Costanzo, A., Guido, F., Marinari, B., Vossio, S., Moretti, F., Levrero, M., & Piccolella, E. (2000) · European Journal of Immunology · doi:10.1002/1521-4141(200009)30:9 · Cited by 30
Requirement for In Vivo Production of IL-4, But Not IL-10, in the Induction of Proliferative Suppression by Filarial Parasites
MacDonald, A. S., Maizels, R. M., Lawrence, R. A., Dransfield, I., & Allen, J. E. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.160.8.4124 · Cited by 28
Self-citation
Brugia pahangi:The Cuticular Glutathione Peroxidase (gp29) Protects Heterologous Membranes from Lipid Peroxidation
Tang, L., Smith, V. P., Gounaris, K., & Selkirk, M. E. (1996) · Experimental Parasitology · doi:10.1006/expr.1996.0041 · Cited by 24
High-Yield Expression and Purification of Recombinant Human Macrophage Migration Inhibitory Factor
Mozetič-Francky, B., Cotič, V., Ritonja, A., Žerovnik, E., & Francky, A. (1997) · Protein Expression and Purification · doi:10.1006/prep.1996.0641 · Cited by 10
Interaction of macrophage-migration-inhibitory factor with haematin
Pennock, J. L., Wipasa, J., Gordge, M. P., & MEYER, D. J. (1998) · Biochemical Journal · doi:10.1042/bj3310905 · Cited by 9
Self-citation
Protein Crystallography
Haitin, Y., & Giladi, M. (2023) · CRC Press eBooks · doi:10.1201/9781003096214-15 · Cited by 3

Flagged first, then by citations

1 of the 58 references couldn’t be matched to a known paper.

Sorted by citations

Immune Regulation by helminth parasites: cellular and molecular mechanisms
Maizels, R. M., & Yazdanbakhsh, M. (2003) · Nature reviews. Immunology · doi:10.1038/nri1183 · Cited by 1,167
Self-citation
Helminth parasites – masters of regulation
Maizels, R. M., Balic, A., Gomez‐Escobar, N., Nair, M. G., Taylor, M. D., & Allen, J. E. (2004) · Immunological Reviews · doi:10.1111/j.0105-2896.2004.00191.x · Cited by 882
Self-citation
Helminth immunoregulation: The role of parasite secreted proteins in modulating host immunity
Hewitson, J. P., Grainger, J. R., & Maizels, R. M. (2009) · Molecular and Biochemical Parasitology · doi:10.1016/j.molbiopara.2009.04.008 · Cited by 742
Self-citation
Modulation of Host Immunity by Helminths: The Expanding Repertoire of Parasite Effector Molecules
Maizels, R. M., Smits, H. H., & McSorley, H. J. (2018) · Immunity · doi:10.1016/j.immuni.2018.10.016 · Cited by 435
Self-citation
ISO-1 Binding to the Tautomerase Active Site of MIF Inhibits Its Pro-inflammatory Activity and Increases Survival in Severe Sepsis
Al‐Abed, Y., Dabideen, D. R., Aljabari, B., Valster, A. H., Messmer, D., Ochani, M., Tanovic, M., Ochani, K., Bacher, M., Nicoletti, F., et al. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.c500243200 · Cited by 309
The secretome of the filarial parasite, Brugia malayi: Proteomic profile of adult excretory–secretory products
Hewitson, J. P., Harcus, Y. M., Curwen, R. S., Dowle, A., Atmadja, A. K., Ashton, P. D., Wilson, A., & Maizels, R. M. (2008) · Molecular and Biochemical Parasitology · doi:10.1016/j.molbiopara.2008.02.007 · Cited by 244
Self-citation
Helminth Immunomodulation in Autoimmune Disease
Smallwood, T. B., Giacomin, P., Loukas, A. C., Mulvenna, J. P., Clark, R. J., & Miles, J. J. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00453 · Cited by 232
Immunomodulation by filarial nematodes
Hoerauf, A. M., Satoguina, J., Saeftel, M., & Specht, S. (2005) · Parasite Immunology · doi:10.1111/j.1365-3024.2005.00792.x · Cited by 195
Release of Small RNA-containing Exosome-like Vesicles from the Human Filarial Parasite Brugia malayi
Zamanian, M., Fraser, L. M., Agbedanu, P. N., Harischandra, H., Moorhead, A. R., Day, T. A., Bartholomay, L. C., & Kimber, M. J. (2015) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0004069 · Cited by 164
Use of RNA interference to investigate gene function in the human filarial nematode parasite Brugia malayi
Aboobaker, A. A., & Blaxter, M. (2003) · Molecular and Biochemical Parasitology · doi:10.1016/s0166-6851(03)00092-6 · Cited by 152
Stage- and Gender-Specific Proteomic Analysis of Brugia malayi Excretory-Secretory Products
Moreno, Y., & Geary, T. G. (2008) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0000326 · Cited by 146
Nematoda: Genes, Genomes and the Evolution of Parasitism
Blaxter, M. (2003) · Advances in Parasitology/Advances in parasitology · doi:10.1016/s0065-308x(03)54003-9 · Cited by 131
Proteinase inhibitors and helminth parasite infection
Knox, D. P. (2006) · Parasite Immunology · doi:10.1111/j.1365-3024.2006.00913.x · Cited by 118
Critical Role of Macrophage Migration Inhibitory Factor Activity in Experimental Autoimmune Diabetes
Cvetković, I., Al‐Abed, Y., Miljković, D. M., Maksimović‐Ivanić, D., Roth, J., Bacher, M., Lan, H. Y., Nicoletti, F., & Stošić‐Grujičić, S. (2005) · Endocrinology · doi:10.1210/en.2004-1393 · Cited by 116
Involvement of the Cytokine MIF in the Snail Host Immune Response to the Parasite Schistosoma mansoni
Garcia, A. B., Pierce, R. J., Gourbal, B., Werkmeister, E., Colinet, D., Reichhart, J., Dissous, C., & Coustau, C. (2010) · PLoS Pathogens · doi:10.1371/journal.ppat.1001115 · Cited by 114
Brugia malayi Microfilariae Induce Cell Death in Human Dendritic Cells, Inhibit Their Ability to Make IL-12 and IL-10, and Reduce Their Capacity to Activate CD4+ T Cells
Semnani, R. T., Liu, A. Y., Sabzevari, H., Kubofcik, J., Zhou, J., Gilden, J. K., & Nutman, T. B. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.171.4.1950 · Cited by 114
Looking beyond the induction of Th2 responses to explain immunomodulation by helminths
Nutman, T. B. (2015) · Parasite Immunology · doi:10.1111/pim.12194 · Cited by 111
Structural and Functional Characterization of a Secreted Hookworm Macrophage Migration Inhibitory Factor (MIF) That Interacts with the Human MIF Receptor CD74
Cho, Y., Jones, B. F., Vermeire, J. J., Leng, L., Difedele, L. M., Harrison, L. M., Xiong, H., Kwong, Y.-K. A., Chen, Y., Bucala, R., et al. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m702950200 · Cited by 103
The beneficial helminth parasite?
McKay, D. M. (2005) · Parasitology · doi:10.1017/s003118200500884x · Cited by 98
Orthologs of macrophage migration inhibitory factor from parasitic nematodes
Vermeire, J. J., Cho, Y., Lolis, E., Bucala, R., & Cappello, M. (2008) · Trends in Parasitology · doi:10.1016/j.pt.2008.04.007 · Cited by 95
Functional Characterization of thePlasmodium falciparumandP. bergheiHomologues of Macrophage Migration Inhibitory Factor
Augustijn, K. D., Kleemann, R., Thompson, J., Kooistra, T., Crawford, C. E., Reece, S. E., Pain, A., Siebum, A. H. G., Janse, C. J., & Waters, A. P. (2006) · Infection and Immunity · doi:10.1128/iai.00902-06 · Cited by 84
Filaria-Induced Immune Evasion: Suppression by the Infective Stage of Brugia malayi at the Earliest Host-Parasite Interface
Semnani, R. T., Law, M. A., Kubofcik, J., & Nutman, T. B. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.10.6229 · Cited by 83
Macrophage Migration Inhibitory Factor Homologs of Anisakis simplex Suppress Th2 Response in Allergic Airway Inflammation Model via CD4+CD25+Foxp3+ T Cell Recruitment
Park, S. K., Cho, M. K., Park, H.-K., Lee, K. H., Lee, S. J., Choi, S. H., Ock, M. S., Jeong, H. J., Lee, M. H., & Yu, H. S. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0803533 · Cited by 82
MIF homologues from a filarial nematode parasite synergize with IL-4 to induce alternative activation of host macrophages
Prieto-Lafuente, L., Gregory, W. F., Allen, J. E., & Maizels, R. M. (2009) · Journal of Leukocyte Biology · doi:10.1189/jlb.0808459 · Cited by 79
Self-citation
Ribosomal Protein S19 Interacts with Macrophage Migration Inhibitory Factor and Attenuates Its Pro-inflammatory Function
Filip, A.-M., Klug, J., Çaylı, S., Fröhlich, S., Henke, T., Lacher, P., Eickhoff, R., Bulau, P., Linder, M. I., Carlsson‐Skwirut, C., et al. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m808620200 · Cited by 68
The Role of MIF on Eosinophil Biology and Eosinophilic Inflammation
Bozza, M. T., Lintomen, L., Kitoko, J. Z., Paiva, C. N., & Olsen, P. C. (2019) · Clinical Reviews in Allergy & Immunology · doi:10.1007/s12016-019-08726-z · Cited by 66
Signal sequence analysis of expressed sequence tags from the nematode Nippostrongylus brasiliensisand the evolution of secreted proteins in parasites
Harcus, Y. M., Parkinson, J., Fernández, C., Daub, J., Selkirk, M. E., Blaxter, M., & Maizels, R. M. (2004) · Genome biology · doi:10.1186/gb-2004-5-6-r39 · Cited by 66
Self-citation
Modulation of Specific and Allergy‐Related Immune Responses by Helminths
Daniłowicz-Luebert, E., O’Regan, N. L., Steinfelder, S., & Hartmann, S. (2011) · BioMed Research International · doi:10.1155/2011/821578 · Cited by 64
Biochemical and Immunological Characterization of Toxoplasma gondii Macrophage Migration Inhibitory Factor
Sommerville, C., Richardson, J. M., Williams, R., Mottram, J. C., Roberts, C. W., Alexander, J. K., & Henriquez, F. L. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.419911 · Cited by 62
The non-mammalian MIF superfamily
Sparkes, A., BAETSELIER, P. D., Roelants, K., Trez, C. D., Magez, S., Ginderachter, J. A. V., Raes, G., Bucala, R., & Stijlemans, B. (2016) · Immunobiology · doi:10.1016/j.imbio.2016.10.006 · Cited by 56
Heterologous expression of the filarial nematode alt gene products reveals their potential to inhibit immune function
Gomez‐Escobar, N., Bennett, C. L., Prieto-Lafuente, L., Aebischer, T., Blackburn, C. C., & Maizels, R. M. (2005) · BMC Biology · doi:10.1186/1741-7007-3-8 · Cited by 50
Self-citation
Wuchereria bancrofti filaria activates human dendritic cells and polarizes T helper 1 and regulatory T cells via toll-like receptor 4
Mukherjee, S., Karnam, A., Das, M., Babu, S. P. S., & Bayry, J. (2019) · Communications Biology · doi:10.1038/s42003-019-0392-8 · Cited by 50
Toward an understanding of the interaction between filarial parasites and host antigen‐presenting cells
Semnani, R. T., & Nutman, T. B. (2004) · Immunological Reviews · doi:10.1111/j.0105-2896.2004.00196.x · Cited by 47
Characterisation of macrophage migration inhibitory factor from Eimeria species infectious to chickens☆
Miska, K. B., Fetterer, R. H., Lillehoj, H. S., Jenkins, M. C., Allen, P. C., & Harper, S. B. (2006) · Molecular and Biochemical Parasitology · doi:10.1016/j.molbiopara.2006.10.020 · Cited by 44
What Can Parasites Tell Us About the Pathogenesis and Treatment of Asthma and Allergic Diseases
Bohnacker, S., Troisi, F., Jiménez, M. D. L. R., & Bieren, J. E. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.02106 · Cited by 43
A macrophage migration inhibitory factor like oxidoreductase from pearl oyster Pinctada fucata involved in innate immune responses
Cui, S., Zhang, D., Jiang, S., Pu, H., Hu, Y., Guo, H., Chen, M., Su, T., & Zhu, C. (2011) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2011.03.009 · Cited by 40
Hippocampal gene expression changes during age-related cognitive decline
Pawlowski, T. L., Bellush, L. L., Wright, A. W., Walker, J. P., Colvin, R. A., & Huentelman, M. J. (2008) · Brain Research · doi:10.1016/j.brainres.2008.12.039 · Cited by 40
Molecular cloning and characterization of macrophage migration inhibitory factor from small abalone Haliotis diversicolor supertexta
Wang, B., Zhang, Z., Wang, Y., Zou, Z., Wang, G., Wang, S., Jia, X., & Lin, P. (2009) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2009.04.004 · Cited by 38
The Immune Response to Nematode Infection
Stear, M. J., Preston, S., Piedrafita, D. M., & Donskow‐Łysoniewska, K. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24032283 · Cited by 36
Molecular cloning and identification of macrophage migration inhibitory factor (MIF) in teleost fish
Jin, H., Xiang, L.-X., & Shao, J.-Z. (2007) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2007.02.004 · Cited by 35
Exploring the immunology of parasitism – from surface antigens to the hygiene hypothesis
Maizels, R. M. (2009) · Parasitology · doi:10.1017/s0031182009006106 · Cited by 34
Self-citation
A macrophage migration inhibitory factor like gene from scallop Chlamys farreri: Involvement in immune response and wound healing
Li, F., Huang, S., Wang, L., Yang, J., Zhang, H., Qiu, L., Li, L., & Song, L. (2010) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2010.08.009 · Cited by 33
The crystal structures of macrophage migration inhibitory factor from Plasmodium falciparum and Plasmodium berghei
Dobson, S. E., Augustijn, K. D., Brannigan, J. A., Schnick, C., Janse, C. J., Dodson, E. J., Waters, A. P., & Wilkinson, A. J. (2009) · Protein Science · doi:10.1002/pro.263 · Cited by 33
Haemaphysalis longicornis: Molecular characterization of a homologue of the macrophage migration inhibitory factor from the partially fed ticks
Umemiya‐Shirafuji, R., Hatta, T., Liao, M., Tanaka, M., Zhou, J., Inoue, N., & Fujisaki, K. (2006) · Experimental Parasitology · doi:10.1016/j.exppara.2006.07.006 · Cited by 32
Characterization of a secreted macrophage migration inhibitory factor homologue of the parasitic nematode Strongyloides acting at the parasite–host cell interface
Younis, A. E., Soblik, H., Ajonina‐Ekoti, I., Erttmann, K. D., Lüersen, K., Liebau, E., & Brattig, N. W. (2011) · Microbes and Infection · doi:10.1016/j.micinf.2011.09.006 · Cited by 32
Gender-Associated Genes in Filarial Nematodes Are Important for Reproduction and Potential Intervention Targets
Li, B.-W., Rush, A. C., Jiang, D., Mitreva, M., Abubucker, S., & Weil, G. J. (2011) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0000947 · Cited by 31
Helminth-Derived Immunomodulatory Molecules
Adisakwattana, P., Saunders, S. P., Nel, H. J., & Fallon, P. G. (2009) · Advances in experimental medicine and biology · doi:10.1007/978-1-4419-1601-3_8 · Cited by 31
TLR 2‐dependent amelioration of allergic airway inflammation by parasitic nematode type II MIF in mice
Cho, M. K., Park, M. K., Kang, S. A., Park, S. K., Lyu, J. H., Kim, D. ‐., Park, H. ‐., & Yu, H. S. (2015) · Parasite Immunology · doi:10.1111/pim.12172 · Cited by 30
Macrophage migration inhibitory factor (MIF) in chinese amphioxus as a molecular marker of immune evolution during the transition of invertebrate/vertebrate
Du, J., Xie, X., Chen, H., Yang, W., Dong, M., Su, J., Wang, Y., Yu, C., Zhang, S., & Xu, A. (2004) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2004.04.001 · Cited by 30
A genome sequence survey of the filarial nematode Brugia malayi: repeats, gene discovery, and comparative genomics
Whitton, C., Daub, J., Quail, M. A., Hall, N., Foster, J. M., Ware, J., Ganatra, M. B., Slatko, B. E., Barrell, B. G., & Blaxter, M. (2004) · Molecular and Biochemical Parasitology · doi:10.1016/j.molbiopara.2004.05.013 · Cited by 30
Detection of Plasmodium falciparum derived macrophage migration inhibitory factor homologue in the sera of malaria patients
Shao, D., Han, Z., Lin, Y., Zhang, L., Zhong, X., Feng, M.-L., Guo, Y., & Wang, H. (2008) · Acta Tropica · doi:10.1016/j.actatropica.2007.12.008 · Cited by 27
A macrophage migration inhibitory factor-like tautomerase from Teladorsagia circumcincta (Nematoda: Strongylida)
Nisbet, A. J., BELL, N. E. V., McNeilly, T. N., Knox, D. P., Maizels, R. M., MEIKLE, L. I., WILDBLOOD, L. A., & Matthews, J. B. (2010) · Parasite Immunology · doi:10.1111/j.1365-3024.2010.01215.x · Cited by 26
Self-citation
Structural and functional comparison of MIF ortholog from Plasmodium yoelii with MIF from its rodent host
Shao, D., Zhong, X., Zhou, Y., Han, Z., Lin, Y., Wang, Z., Bu, L., Zhang, L., Su, X., & Wang, H. (2009) · Molecular Immunology · doi:10.1016/j.molimm.2009.10.037 · Cited by 25
HcTTR: a novel antagonist against goat interleukin 4 derived from the excretory and secretory products of Haemonchus contortus
Tian, X., Lu, M., Wang, W., Jia, C., Ehsan, M., Yan, R., Xu, L., Song, X., & Li, X. (2019) · Veterinary Research · doi:10.1186/s13567-019-0661-z · Cited by 24
Structures of Leishmania major orthologues of macrophage migration inhibitory factor
Richardson, J. M., Morrison, L. S., Bland, N. D., Bruce, S., Coombs, G. H., Mottram, J. C., & Walkinshaw, M. D. (2009) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2009.01.030 · Cited by 24
Self-citation
Characterization of a secreted macrophage migration inhibitory factor homologue of the parasitic nematode Haemonchus Contortus acting at the parasite-host cell interface
Wang, Y., Lu, M., Wang, S., Ehsan, M., Yan, R., Song, X., Xu, L., & Li, X. (2017) · Oncotarget · doi:10.18632/oncotarget.16675 · Cited by 23
Regulatory Cells and Immunosuppressive Cytokines: Parasite-Derived Factors Induce Immune Polarization
Ouaissi, A. (2007) · BioMed Research International · doi:10.1155/2007/94971 · Cited by 23
Comparative analysis of macrophage migration inhibitory factors (MIFs) from the parasitic nematode Onchocerca volvulus and the free-living nematode Caenorhabditis elegans
Ajonina‐Ekoti, I., Kurosinski, M. A., Younis, A. E., Ndjonka, D., Tanyi, M. K., Achukwi, M. D., Eisenbarth, A., Ajonina, C., Lüersen, K., Breloer, M., et al. (2013) · Parasitology Research · doi:10.1007/s00436-013-3513-1 · Cited by 22
Structural and Functional Characterization of a Macrophage Migration Inhibitory Factor Homologue from the Marine Cyanobacterium Prochlorococcus marinus,
Wasiel, A. A., Rozeboom, H. J., Hauke, D., Baas, B., Zandvoort, E., Quax, W. J., Thunnissen, A. M. W. H., & Poelarends, G. J. (2010) · Biochemistry · doi:10.1021/bi1008276 · Cited by 22
Ostertagia ostertagi macrophage migration inhibitory factor is present in all developmental stages and may cross-regulate host functions through interaction with the host receptor
Qu, G., Fetterer, R. H., Leng, L., Du, X., Zarlenga, D. S., Shen, Z., Han, W., Bucala, R., & Tuo, W. (2014) · International Journal for Parasitology · doi:10.1016/j.ijpara.2014.01.009 · Cited by 21
Nematode Orthologs of Macrophage Migration Inhibitory Factor (MIF) as Modulators of the Host Immune Response and Potential Therapeutic Targets
Karabowicz, J., Długosz, E., Bąska, P., & Wiśniewski, M. (2022) · Pathogens · doi:10.3390/pathogens11020258 · Cited by 21
Molecular and functional characterization of macrophage migration inhibitory factor (MIF) homolog of human from lymphatic filarial parasite Wuchereria bancrofti
Sharma, R., Hoti, S. L., Meena, R. L., Vasuki, V., Sankari, T., & Kaliraj, P. (2012) · Parasitology Research · doi:10.1007/s00436-012-3051-2 · Cited by 21
Secreted filarial nematode galectins modulate host immune cells
Loghry, H. J., Sondjaja, N. A., Minkler, S. J., & Kimber, M. J. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.952104 · Cited by 20
Secretory products from infective forms of Nippostrongylus brasiliensis induce a rapid allergic airway inflammatory response
Marsland, B. J., Camberis, M., & Gros, G. S. L. (2005) · Immunology and Cell Biology · doi:10.1111/j.1440-1711.2005.01303.x · Cited by 20
Control of filarial infections: not the beginning of the end, but more research is needed
Hoerauf, A. M. (2003) · Current Opinion in Infectious Diseases · doi:10.1097/00001432-200310000-00006 · Cited by 20
Molecular cloning, characterization and expression analysis of macrophage migration inhibitory protein (MIF) in Chinese mitten crab, Eriocheir sinensis
Li, W., Jin, X., He, L., Wang, Y., Chen, L., Jiang, H., & Wang, Q. (2010) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2010.11.008 · Cited by 19
Distinct immunoregulatory properties of macrophage migration inhibitory factors encoded by Eimeria parasites and their chicken host
Jang, S. I., Lillehoj, H. S., Lee, S. H., Kim, D., Pagès, M., Hong, Y. H., Min, W., & Lillehoj, E. P. (2011) · Vaccine · doi:10.1016/j.vaccine.2011.09.038 · Cited by 18
Protective Effect Against Toxoplasmosis in BALB/c Mice Vaccinated With Recombinant Toxoplasma gondii MIF, CDPK3, and 14-3-3 Protein Cocktail Vaccine
Liu, F., Wu, M., Wang, J., Wen, H., An, R., Cai, H., Yu, L., Shen, J., Chen, L., & Du, J. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.755792 · Cited by 18
Self-citation
Identification and biochemical characterization of macrophage migration inhibitory factor-2 (MIF-2) homologue of human lymphatic filarial parasite, Wuchereria bancrofti
Chauhan, N., Sharma, R., & Hoti, S. L. (2014) · Acta Tropica · doi:10.1016/j.actatropica.2014.10.009 · Cited by 18
Growth factors and chemotactic factors from parasitic helminths: Molecular evidence for roles in host–parasite interactions versus parasite development
Freitas, T. C., & Pearce, E. J. (2010) · International Journal for Parasitology · doi:10.1016/j.ijpara.2010.02.013 · Cited by 16
Harnessing Immune Evasion Strategy of Lymphatic Filariae: A Therapeutic Approach against Inflammatory and Infective Pathology
Bhoj, P. S., Togre, N. S., Khatri, V., & Goswami, K. (2022) · Vaccines · doi:10.3390/vaccines10081235 · Cited by 15
Dermacentor variabilis: Characterization and modeling of macrophage migration inhibitory factor with phylogenetic comparisons to other ticks, insects and parasitic nematodes
Wasala, N. B., & Jaworski, D. C. (2012) · Experimental Parasitology · doi:10.1016/j.exppara.2011.12.010 · Cited by 15
Elevated Levels of thePlasmodium yoeliiHomologue of Macrophage Migration Inhibitory Factor Attenuate Blood-Stage Malaria
Thorat, S., Daly, T. M., Bergman, L. W., & Burns, J. M. (2010) · Infection and Immunity · doi:10.1128/iai.00277-10 · Cited by 14
Parasitomimetics: Can We Utilize Parasite-Derived Immunomodulatory Molecules for Interventions to Immunological Disorders?
Nagai, K., & Goto, Y. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.824695 · Cited by 14
Differential immunomodulation in human monocytes versus macrophages by filarial cystatin
Venugopal, G., Mueller, M., Hartmann, S., & Steinfelder, S. (2017) · PLoS ONE · doi:10.1371/journal.pone.0188138 · Cited by 14
Evaluation of the immune response induced by DNA vaccines expressing MIF and MCD-1 genes ofTrichinella spiralisin BALB/c mice
Tang, F., Xu, L., Yan, R., Song, X., & Li, X. (2011) · Journal of Helminthology · doi:10.1017/s0022149x11000654 · Cited by 14
Protective Effect Against Toxoplasmosis in BALB/c Mice Vaccinated With Toxoplasma gondii Macrophage Migration Inhibitory Factor
Liu, K., Wen, H., Cai, H., Wu, M., An, R., Chu, D., Yu, L., Shen, J., Chen, L., & Du, J. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.00813 · Cited by 14
Reprint of: The non-mammalian MIF superfamily
Sparkes, A., BAETSELIER, P. D., Roelants, K., Trez, C. D., Magez, S., Ginderachter, J. A. V., Raes, G., Bucala, R., & Stijlemans, B. (2017) · Immunobiology · doi:10.1016/j.imbio.2017.05.004 · Cited by 13
Identification of infiltrating immune cell subsets and heterogeneous macrophages in the lesion microenvironment of hepatic cystic echinococcosis patients with different cyst viability
Yasen, A., Li, W., Ran, B., Aini, A., Wang, Z., Jiang, T., Shao, Y., Aji, T., & Wen, H. (2021) · Acta Tropica · doi:10.1016/j.actatropica.2021.106029 · Cited by 12
Cloning and mRNA expression of macrophage migration inhibitory factor (MIF) gene of large yellow croaker (Pseudosciaena crocea)
Mao, Y., Xu, B., Su, Y., Zhang, Z., Ding, S., Wang, D., & Wang, J. (2010) · Acta Oceanologica Sinica · doi:10.1007/s13131-010-0037-8 · Cited by 11
Self-citation
WISP1 induces the expression of macrophage migration inhibitory factor in human lung fibroblasts through Src kinases and EGFR-activated signaling pathways
Christopoulou, M. E., Skandalis, S. S., Papakonstantinou, E., Stolz, D., & Aletras, A. J. (2023) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00410.2023 · Cited by 8
Expression of helminth genes in Leishmania: an experimental transfection system to test immunological function
Maizels, R. M., Gomez‐Escobar, N., Prieto-Lafuente, L., MURRAY, J., & Aebischer, T. (2007) · Parasite Immunology · doi:10.1111/j.1365-3024.2007.00997.x · Cited by 8
Self-citation
Proteomic analysis of extracellular vesicles and extracellular vesicle-depleted excretory-secretory products of Toxocara canis and Toxocara cati larval cultures
Wu, T. K., Fu, Q., Liotta, J. L., & Bowman, D. D. (2024) · Veterinary Parasitology · doi:10.1016/j.vetpar.2024.110331 · Cited by 7
Macrophage migration inhibitory factor in Nodding syndrome
Benedek, G., Latif, M. A. E., Miller, K., Rivkin, M., Lasu, A. A. R., Riek, L. P., Lako, R. L. L., Edvardson, S., Arbel-Alon, S., Galun, E., et al. (2021) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0009821 · Cited by 7
Expression, purification and characterization of refolded rBm-33 (pepsin inhibitor homolog) from Brugia malayi: A human Lymphatic Filarial parasite
Krishna, N. R. S., Krushna, N. S. A., Narayanan, R. B., Rajan, S. S., & Gunasekaran, K. (2011) · Protein Expression and Purification · doi:10.1016/j.pep.2011.06.014 · Cited by 7
Structural characterization of As-MIF and hJAB1 during the inhibition of cell-cycle regulation
Park, Y.-H., Jeong, S., Ha, K., Yu, H. S., & Jang, S. B. (2017) · BMB Reports · doi:10.5483/bmbrep.2017.50.5.201 · Cited by 6
Role of cysteine-58 and cysteine-95 residues in the thiol di-sulfide oxidoreductase activity of Macrophage Migration Inhibitory Factor-2 of Wuchereria bancrofti
Chauhan, N., & Hoti, S. L. (2015) · Acta Tropica · doi:10.1016/j.actatropica.2015.09.017 · Cited by 6
Wuchereria bancrofti macrophage migration inhibitory factor‐2 (rWbaMIF‐2) ameliorates experimental colitis
Ramani, S., Chauhan, N., Khatri, V., Vitali, C., & Kalyanasundaram, R. (2020) · Parasite Immunology · doi:10.1111/pim.12698 · Cited by 6
Recombinant Brugia malayi pepsin inhibitor (rBm33) induced monocyte function and absence of apoptotic cell death: An in vitro study
Sreenivas, K., Vijayan, K., Babu, S., & Narayanan, R. B. (2012) · Microbial Pathogenesis · doi:10.1016/j.micpath.2012.03.009 · Cited by 5
Epitope Mapping of Monoclonal Antibody 1B9 AgainstPlasmodium falciparum-Derived Macrophage Migration Inhibitory Factor
Wang, Z., Shao, D., Zhong, X., Han, C., Cai, P., & Wang, H. (2009) · Immunological Investigations · doi:10.1080/08820130902912340 · Cited by 5
Macrophage Migration Inhibitory Factor (MIF) is a Key Player in Dry Eye Disease
Rivera, L. A., Hernández, P. E., Vannan, D. T., Reyes, J. L., Rodríguez, T., Sánchez-Barrera, C. Á., González, M. I., Bustos‐Arriaga, J., Ramos, O. A., Juárez, I., et al. (2023) · Ocular Immunology and Inflammation · doi:10.1080/09273948.2023.2290624 · Cited by 3
A filarial parasite-encoded human IL-10 receptor antagonist reveals a novel strategy to modulate host responses
Ricciardi, A., Hassan, S. A., Kamenyeva, O., Bennuru, S., Andersen, J. F., & Nutman, T. B. (2022) · PNAS Nexus · doi:10.1093/pnasnexus/pgac184 · Cited by 3
Characterisation of Macrophage Inhibitory Factor-2 (MIF-2) in Haemonchus contortus and Teladorsagia circumcincta
Umair, S., Knight, J. S., Bouchet, C., Palevich, N., Cleland, S. B., Grant, W. N., & Simpson, H. V. (2022) · Parasitologia · doi:10.3390/parasitologia2040028 · Cited by 3
Structural and functional insights into macrophage migration inhibitory factor from Oncomelania hupensis, the intermediate host of Schistosoma japonicum
Su, Z., Tian, X., Li, H., Wei, Z., Chen, L., Wang, S., Ren, H., Peng, W., Tang, C., Lin, T., et al. (2020) · Biochemical Journal · doi:10.1042/bcj20200068 · Cited by 2
PRESIDENTIAL ADDRESS*CONVENTIONAL WISDOM AND A TALE OF TWO CYTOKINES
Kayes, S. G. (2007) · Journal of Parasitology · doi:10.1645/ge-1455.1
PARASITOLOGICAL AND IMMUNOLOGICAL STUDIES ON THE EFFECTS OF IMMUNIZATION WITH FILARIAL WORM FRACTION ON SUBSEQUENT INFECTION IN RODENT HOST
Joseph, S. K. (2001) · Shodhganga
MIF Proteins from Two Nematodes Recognize Sera of Onchocerciasis Patients and Stimulate Peripheral Blood Mononuclear Cells to Release TNF-α and iL-10 Cytokines
Boursou, D. (2016) · Journal of Diseases and Medicinal Plants · doi:10.11648/j.jdmp.20160202.11
Secreted Proteins, Infectivity and Immunity to the Parasitic Nematode Nippostrongylus brasiliensis
Chan, T. Y. (2011) · Spiral (Imperial College London) · doi:10.25560/9170
Helminth-Derived Immunomodulatory
Adisakwattana, M., & Saunders, S. P. (2009)
A computational assessment of the predicted structures of Human Macrophage Migration Inhibitory Factor 1 orthologs in parasites and its affinity to human CD74 receptor
Machicado, C., & Marcos, L. A. (2017) · Journal of Molecular Recognition · doi:10.1002/jmr.2640

Filarial Nematode Parasites Secrete a Homologue of the Human Cytokine Macrophage Migration Inhibitory Factor
Pastrana, D., Raghavan, N., Fitzgerald, P., Eisinger, S. W., Metz, C., Bucala, R., Schleimer, R., Bickel, C., & Scott, A. L. (1998) · Infection and Immunity · doi:10.1128/iai.66.12.5955-5963.1998 · Cited by 253
Self-citation
Macrophage-migration Inhibitory Factor (MIF) homologues in the host-parasite interaction
Prieto-Lafuente, L. (2007) · OpenGrey (Institut de l'Information Scientifique et Technique)
Molecular and functional characterization of macrophage migration inhibitory factor (MIF) homolog of human from lymphatic filarial parasite Wuchereria bancrofti
Sharma, R., Hoti, S. L., Meena, R. L., Vasuki, V., Sankari, T., & Kaliraj, P. (2012) · Parasitology Research · doi:10.1007/s00436-012-3051-2 · Cited by 21
Nematode Orthologs of Macrophage Migration Inhibitory Factor (MIF) as Modulators of the Host Immune Response and Potential Therapeutic Targets
Karabowicz, J., Długosz, E., Bąska, P., & Wiśniewski, M. (2022) · Pathogens · doi:10.3390/pathogens11020258 · Cited by 21
Parasite MIF Orthologs
Holowka, T., & Bucala, R. (2017) · Springer eBooks · doi:10.1007/978-3-319-52354-5_14

Authors: Zang, X., Taylor, P., Wang, J. M., Meyer, D. J., Scott, A. L., Walkinshaw, M. D., & Maizels, R. M.
Affiliations: University of Edinburgh (GB)
London School of Hygiene & Tropical Medicine (GB)
Johns Hopkins University (US)
Corresponding author: Zang, Xingxing
Maizels, Rick M.
ORCID: Zang, Xingxing
Taylor, Paul
Scott, Alan L.
Walkinshaw, Malcolm D.
Maizels, Rick M.
Venue: Journal of Biological Chemistry
Publisher: Elsevier BV
Published: 2002-11
Volume: 277
Issue: 46
Pages: 44261-44267
ISSN: 0021-9258 (ISSN-L)
DOI: 10.1074/jbc.m204655200
OpenAlex: W2002006009
Cited by: 108
References: 58
Citations by year: 2024: 1 · 2023: 3 · 2022: 6 · 2021: 3 · 2020: 3 · 2019: 4 · 2018: 3 · 2017: 8 · 2016: 2 · 2015: 4 · 2014: 2 · 2013: 2 · 2012: 4
FWCI: 1.98
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
creativecommons.org/licenses/by/4.0/ (vor, 6559 d)
Locations: Journal of Biological Chemistry (publishedVersion, cc-by)
PubMed (publishedVersion)
Science and Technology Facilities Council (submittedVersion)
LSHTM Research Online (London School of Hygiene and Tropical Medicine) (submittedVersion)
Funders: Wellcome Trust
European Commission
Topics: Life Sciences › Immunology and Microbiology › Immunology › Macrophage Migration Inhibitory Factor
Life Sciences › Immunology and Microbiology › Parasitology › Parasites and Host Interactions
Health Sciences › Medicine › Infectious Diseases › Parasitic Diseases Research and Treatment
Keywords: macrophage migration inhibitory factor, Brugia malayi, tautomerase activity, N-terminal proline, crystal structure, immune evasion, interleukin-8, TNF-α
MeSH terms: Amino Acid Sequence, Animals, Calcium, Cloning, Molecular, Dose-Response Relationship, Drug, Enzyme-Linked Immunosorbent Assay, Escherichia coli, Humans, Macrophage Migration-Inhibitory Factors, Models, Molecular, Molecular Sequence Data, Monocytes, Protein Conformation, Tumor Necrosis Factor-alpha, Blotting, Western, Protozoan Proteins, Interleukin-8, Brugia malayi, Protein Structure, Secondary, Protein Structure, Tertiary, Crystallography, X-Ray, Reverse Transcriptase Polymerase Chain Reaction

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Homologues of Human Macrophage Migration Inhibitory Factor from a Parasitic Nematode

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks