Maizels, Rick M.

Diversity and dialogue in immunity to helminths

Allen, J. E., & Maizels, R. M. (2011) · Nature reviews. Immunology

Parasites and Host InteractionsIL-33, ST2, and ILC Pathways

Cited by 831

Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity

Buck, A. H., Coakley, G., Simbari, F., McSorley, H. J., Quintana, J. F., Le Bihan, T., Kumar, S., Abreu-Goodger, C., Lear, M., Harcus, Y., et al. (2014) · Nature Communications

Parasites and Host InteractionsExtracellular vesicles in disease

Cited by 770

Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-β pathway

Grainger, J. R., Smith, K. A., Hewitson, J. P., McSorley, H. J., Harcus, Y., Filbey, K. J., Finney, C. A. M., Greenwood, E. J. D., Knox, D. P., Wilson, M. S., et al. (2010) · Journal of Experimental Medicine

Parasites and Host InteractionsT-cell and B-cell Immunology

Cited by 469

Modulation of Host Immunity by Helminths: The Expanding Repertoire of Parasite Effector Molecules

Maizels, R. M., Smits, H. H., & McSorley, H. J. (2018) · Immunity

Parasites and Host InteractionsHelminth infection and control

Cited by 435

Removal of regulatory T cell activity reverses hyporesponsiveness and leads to filarial parasite clearance in vivo

Taylor, M. D., LeGoff, L., Harris, A., Malone, E., Allen, J. E., & Maizels, R. M. (2005) · The Journal of Immunology

Parasitic Diseases Research and TreatmentParasites and Host Interactions

Cited by 294

A macrophage-pericyte axis directs tissue restoration via amphiregulin-induced transforming growth factor beta activation

Minutti, C. M., Modak, R. V., Macdonald, F., Li, F., Smyth, D. J., Dorward, D. A., Blair, N., Husovsky, C., Muir, A., Giampazolias, E., et al. (2019) · Immunity

Wound Healing and TreatmentsTGF-β signaling in diseases

Cited by 228

Bm-CPI-2, a cystatin homolog secreted by the filarial parasite Brugia malayi, inhibits class II MHC-restricted antigen processing

Manoury, B., Gregory, W. F., Maizels, R. M., & Watts, C. (2001) · Current Biology

Parasitic Diseases Research and TreatmentParasites and Host Interactions

Cited by 223

Extracellular vesicles from a helminth parasite suppress macrophage activation and constitute an effective vaccine for protective immunity

Coakley, G., McCaskill, J. L., Borger, J. G., Simbari, F., Robertson, E., Millar, M., Harcus, Y., McSorley, H. J., Maizels, R. M., & Buck, A. H. (2017) · Cell Reports

Parasites and Host InteractionsHelminth infection and control

Cited by 219

A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells

Johnston, C. J. C., Smyth, D. J., Kodali, R. B., White, M. P. J., Harcus, Y., Filbey, K. J., Hewitson, J. P., Hinck, C. S., Ivens, A., Kemter, A. M., et al. (2017) · Nature Communications

Parasites and Host InteractionsT-cell and B-cell Immunology

Cited by 197

HpARI protein secreted by a helminth parasite suppresses interleukin-33

Osbourn, M., Soares, D. C., Vacca, F., Cohen, E. S., Scott, I. C., Gregory, W. F., Smyth, D. J., Toivakka, M., Kemter, A. M., le Bihan, T., et al. (2017) · Immunity

IL-33, ST2, and ILC PathwaysParasites and Host Interactions

Cited by 178

Blockade of IL-33 release and suppression of type 2 innate lymphoid cell responses by helminth secreted products in airway allergy

McSorley, H. J., Blair, N. F., Smith, K. A., McKenzie, A. N. J., & Maizels, R. M. (2014) · Mucosal Immunology

IL-33, ST2, and ILC PathwaysAsthma and respiratory diseases

Cited by 163

Identification of tgh-2, a Filarial Nematode Homolog of Caenorhabditis elegans daf-7 and Human Transforming Growth Factor β, Expressed in Microfilarial and Adult Stages of Brugia malayi

Gomez-Escobar, N., Gregory, W. F., & Maizels, R. M. (2000) · Infection and Immunity

Parasitic Diseases Research and TreatmentParasites and Host Interactions

Cited by 162

Innate and adaptive type 2 immune cell responses in genetically controlled resistance to intestinal helminth infection

Filbey, K. J., Grainger, J. R., Smith, K. A., Boon, L., van Rooijen, N., Harcus, Y., Jenkins, S., Hewitson, J. P., & Maizels, R. M. (2014) · Immunology & Cell Biology

Parasites and Host InteractionsHelminth infection and control

Cited by 130

Homologues of Human Macrophage Migration Inhibitory Factor from a Parasitic Nematode

Zang, X., Taylor, P., Wang, J. M., Meyer, D. J., Scott, A. L., Walkinshaw, M. D., & Maizels, R. M. (2002) · Journal of Biological Chemistry

Macrophage Migration Inhibitory FactorParasites and Host Interactions

Cited by 108

Secreted venom allergen-like proteins of helminths: Conserved modulators of host responses in animals and plants

Wilbers, R. H. P., Schneiter, R., Holterman, M. H. M., Drurey, C., Smant, G., Asojo, O. A., Maizels, R. M., & Lozano-Torres, J. L. (2018) · PLOS Pathogens

Parasites and Host InteractionsHelminth infection and control

Cited by 84

MIF homologues from a filarial nematode parasite synergize with IL-4 to induce alternative activation of host macrophages

Prieto-Lafuente, L., Gregory, W. F., Allen, J. E., & Maizels, R. M. (2009) · Journal of Leukocyte Biology

Macrophage Migration Inhibitory FactorParasitic Diseases Research and Treatment

Cited by 79

Secretion of protective antigens by tissue-stage nematode larvae revealed by proteomic analysis and vaccination-induced sterile immunity

Hewitson, J. P., Ivens, A. C., Harcus, Y., Filbey, K. J., McSorley, H. J., Murray, J., Bridgett, S., Ashford, D., Dowle, A. A., & Maizels, R. M. (2013) · PLoS Pathogens

Parasites and Host InteractionsHelminth infection and control

Cited by 71

TGF-β mimic proteins form an extended gene family in the murine parasite Heligmosomoides polygyrus

Smyth, D. J., Harcus, Y., White, M. P. J., Gregory, W. F., Nahler, J., Stephens, I., Toke-Bjolgerud, E., Hewitson, J. P., Ivens, A., McSorley, H. J., et al. (2018) · International Journal for Parasitology

Parasites and Host InteractionsHelminth infection and control

Cited by 66