Production of Reactive Oxygen Species by Mitochondria

Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria

Turrens, J. F., & Boveris, A. (1980) · Biochemical Journal · doi:10.1042/bj1910421 · Cited by 1,601

Topology of superoxide production from different sites in the mitochondrial electron transport chain

St-Pierre, J., Buckingham, J. A., Roebuck, S. J., & Brand, M. D. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m207217200 · Cited by 1,545

Complete Structure of the 11-Subunit Bovine Mitochondrial Cytochrome bc 1 Complex

Iwata, S., Lee, J. W., Okada, K., Lee, J. K., Iwata, M., Rasmussen, B., Link, T. A., Ramaswamy, S., & Jap, B. K. (1998) · Science · doi:10.1126/science.281.5373.64 · Cited by 1,253

Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria

Turrens, J. F., Alexandre, A., & Lehninger, A. L. (1985) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(85)90293-0 · Cited by 1,214

Oxygen activation and the conservation of energy in cell respiration

Babcock, Ǵ., & Wikström, M. K. F. (1992) · Nature · doi:10.1038/356301a0 · Cited by 1,126

Biochemical properties of subsarcolemmal and interfibrillar mitochondria isolated from rat cardiac muscle

Palmer, J. W., Tandler, B., & Hoppel, C. L. (1977) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)75283-1 · Cited by 830

Mitochondrial Dysfunction in Cardiac Disease: Ischemia–Reperfusion, Aging, and Heart Failure

Lesnefsky, E. J., Moghaddas, S., Tandler, B., Kerner, J., & Hoppel, C. L. (2001) · Journal of Molecular and Cellular Cardiology · doi:10.1006/jmcc.2001.1378 · Cited by 719

Voltage-dependent anion channels control the release of the superoxide anion from mitochondria to cytosol

Han, D., Antunes, F., Canali, R., Rettori, D., & Cadenas, E. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m210269200 · Cited by 711

The protonmotive Q cycle. Energy transduction by coupling of proton translocation to electron transfer by the cytochrome bc1 complex.

Trumpower, B. L. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)38410-8 · Cited by 598

Detection of catalase in rat heart mitochondria.

Radi, R., Turrens, J. F., Chang, L. Y., Bush, K. M., Crapo, J. D., & Freeman, B. A. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)54740-2 · Cited by 573

A complex dietary supplement augments spatial learning, brain mass, and mitochondrial electron transport chain activity in aging mice

Aksenov, V., Long, J., Liu, J., Szechtman, H., Khanna, P., Matravadia, S., & Rollo, C. D. (2011) · AGE · doi:10.1007/s11357-011-9325-2 · Cited by 24

Anticonvulsant effect of (E)-2-benzylidene-4-phenyl-1,3-diselenole in a pilocarpine model in mice

Wilhelm, E. A., Jessé, C. R., Roman, S. S., Bortolatto, C. F., & Nogueira, C. W. (2010) · Life Sciences · doi:10.1016/j.lfs.2010.09.022 · Cited by 23

Ursolic-Acid-Enriched Herba Cynomorii Extract Protects against Oxidant Injury in H9c2 Cells and Rat Myocardium by Increasing Mitochondrial ATP Generation Capacity and Enhancing Cellular Glutathione Redox Cycling, Possibly through Mitochondrial Uncoupling

Chen, J., & Ko, K. M. (2013) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2013/924128 · Cited by 23

Molecular analysis of the Sydney rock oyster (Saccostrea glomerata) CO2 stress response

Ertl, N. G., O’Connor, W. A., Wiegand, A. N., & Elizur, A. (2016) · Climate Change Responses · doi:10.1186/s40665-016-0019-y · Cited by 23

MiR-195 modulates oxidative stress-induced apoptosis and mitochondrial energy production in human trophoblasts via flavin adenine dinucleotide-dependent oxidoreductase domain-containing protein 1 and pyruvate dehydrogenase phosphatase regulatory subunit

Wang, H., Zhang, L., Guo, X., Bai, Y., Li, Y., Sha, J., Peng, C., Wang, Y., & Liu, M. (2017) · Journal of Hypertension · doi:10.1097/hjh.0000000000001529 · Cited by 23

Mitochondrial Dysfunction Causes Oxidative Stress and Tapetal Apoptosis in Chemical Hybridization Reagent-Induced Male Sterility in Wheat

Wang, S., Zhang, Y., Song, Q., Fang, Z., Chen, Z., Zhang, Y., Zhang, L., Zhang, L., Niu, N., Ma, S., et al. (2018) · Frontiers in Plant Science · doi:10.3389/fpls.2017.02217 · Cited by 23

Analysis of digital gene expression profiling in the gonad of male silkworms (Bombyx mori) under fluoride stress

Tang, W., Xiao, Y., Li, G., Zheng, X., Yin, Y., Wang, L., & Zhu, Y. (2018) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2018.01.028 · Cited by 23

Fetal Programming and Sexual Dimorphism of Mitochondrial Protein Expression and Activity of Hearts of Prenatally Hypoxic Guinea Pig Offspring

Thompson, L. P., Song, H., & Polster, B. M. (2019) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2019/7210249 · Cited by 24

Overexpression of reactive oxygen species modulator 1 is associated with advanced grades of bladder cancer

Ghasemi, H., Amini, M. A., Pegah, A., Azizi, E., Tayebinia, H., Khanverdilou, S., Mousavi‐Bahar, S. H., & Alizamir, A. (2020) · Molecular Biology Reports · doi:10.1007/s11033-020-05702-1 · Cited by 23

The diverse and complex roles of radiation on cancer treatment: therapeutic target and genome maintenance.

Baskar, R., Yap, S. P., Chua, K. L. M., & Itahana, K. (2012) · Europe PMC (PubMed Central) · Cited by 25

The oxidative stress in breast tumors of postmenopausal women is ERα/ERβ ratio dependent

Sastre‐Serra, J., Nadal‐Serrano, M., Pons, D. G., Valle, A., Garau, I., Garcia-Bonafe, M., Oliver, J., & Roca, P. (2013) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2013.03.005 · Cited by 23

STEAP4 and insulin resistance

Chen, X., Huang, Z., Zhou, B., Wang, H., Jia, G., Liu, G., & Zhao, H. (2014) · Endocrine · doi:10.1007/s12020-014-0230-1 · Cited by 23

Combined exposure to pyrene and fluoranthene and their molecular effects on the Sydney rock oyster, Saccostrea glomerata

Ertl, N. G., O’Connor, W. A., Brooks, P. R., Keats, M., & Elizur, A. (2016) · Aquatic Toxicology · doi:10.1016/j.aquatox.2016.05.012 · Cited by 24

Effects of Post‐Resuscitation Normoxic Therapy on Oxygen‐Sensitive Oxidative Stress in a Rat Model of Cardiac Arrest

Okuma, Y., Becker, L. B., Hayashida, K., Aoki, T., Saeki, K., Nishikimi, M., Shoaib, M., Miyara, S. J., Yin, T., & Shinozaki, K. (2021) · Journal of the American Heart Association · doi:10.1161/jaha.120.018773 · Cited by 22

Effect of Sodium-Glucose Co-transporter Protein 2 Inhibitors on Arrhythmia in Heart Failure Patients With or Without Type 2 Diabetes: A Meta-Analysis of Randomized Controlled Trials

Yin, Z., Zheng, H., & Guo, Z. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.902923 · Cited by 22

Improvement of Mitochondrial Function in Muscle of Genetically Obese Rats after Chronic Supplementation with Proanthocyanidins

Reguera, D. P., Fernández‐Iglesias, A., Díaz, S., Quesada, H., Arola‐Arnal, A., Bladé, C., Salvadó, M. J., & Arola, L. (2011) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf201775v · Cited by 22

Examination of bioenergetic function in the inner mitochondrial membrane peptidase 2-like (Immp2l) mutant mice

Bharadwaj, M. S., Zhou, Y., Molina, A. J. A., Criswell, T. L., & Lu, B. (2014) · Redox Biology · doi:10.1016/j.redox.2014.08.006 · Cited by 22

Increased mitochondrial matrix-directed superoxide production by fatty acid hydroperoxides in skeletal muscle mitochondria

Bhattacharya, A., Lustgarten, M. S., Shi, Y., Liu, Y., Jang, Y. C., Pulliam, D. A., Jernigan, A., & Remmen, H. V. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2010.12.014 · Cited by 22

A targeted mass spectrometry-based approach for the identification and characterization of proteins containing α-aminoadipic and γ-glutamic semialdehyde residues

Chavez, J. D., Bisson, W. H., & Maier, C. S. (2010) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-010-4289-0 · Cited by 22

Synthesis, characterization and efficacy of mitochondrial targeted delivery of TPP-curcumin in rotenone-induced toxicity

Hasan, W., Kori, R. K., Thakre, K., Yadav, R. S., & Jat, D. (2019) · DARU Journal of Pharmaceutical Sciences · doi:10.1007/s40199-019-00283-2 · Cited by 22

Melatonin has profound effects on mitochondrial dynamics in myocardial ischaemia/reperfusion

Dube, K. R., Dhanabalan, K., Salie, R., Blignaut, M., Huisamen, B., & Lochner, A. (2019) · Heliyon · doi:10.1016/j.heliyon.2019.e02659 · Cited by 23

CaMKII activation in early diabetic hearts induces altered sarcoplasmic reticulum-mitochondria signaling

Federico, M., Zavala, M., Vico, T. A., López, S., Portiansky, E. L., Álvarez, S., Abrille, M. C. V., & Palomeque, J. (2021) · Scientific Reports · doi:10.1038/s41598-021-99118-x · Cited by 22

Epitoky in Nereis (Neanthes) virens (Polychaeta: Nereididae): A story about sex and death

Chatelain, É. H., Breton, S., Lemieux, H., & Blier, P. U. (2007) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/j.cbpb.2007.09.006 · Cited by 22

Oxidative stress in critical care medicine

Bernal, M. E., Varón, J., Acosta, P., & Montagnier, L. (2010) · International Journal of Clinical Practice · doi:10.1111/j.1742-1241.2010.02506.x · Cited by 22

Oxidative Stress and Heart Failure

Marı́n-Garcı́a, J. (2010) · Humana Press eBooks · doi:10.1007/978-1-60761-147-9_10 · Cited by 22

Generation of reactive oxygen species in thylakoids from senescing flag leaves of the barley varieties Lomerit and Carina

Krieger‐Liszkay, A., Trösch, M., & Krupinska, K. (2015) · Planta · doi:10.1007/s00425-015-2274-8 · Cited by 22

Bioenergetics of the aging heart and skeletal muscles: Modern concepts and controversies

Tepp, K., Timohhina, N., Puurand, M., Klepinin, A., Chekulayev, V., Shevchuk, I., & Kaambre, T. (2016) · Ageing Research Reviews · doi:10.1016/j.arr.2016.04.001 · Cited by 21

Sex-related differences in aerobic capacities and reactive oxygen species metabolism in the silver eel

Amérand, A., Vettier, A., Cann-Moisan, C., Belhomme, M., & Sebert, P. (2009) · Fish Physiology and Biochemistry · doi:10.1007/s10695-009-9348-0 · Cited by 21

Methylene blue treatment in experimental ischemic stroke: A mini-review

Zhao, J., & Duong, T. (2016) · Brain Circulation · doi:10.4103/2394-8108.178548 · Cited by 21

Effects hydrogen sulfide on the antioxidant system and membrane stability in mitochondria of Malus hupehensis under NaCl stress

Wei, G.-Q., Zhang, W.-W., Cao, H., Yue, S., Li, P., & Yang, H.-Q. (2018) · Biologia Plantarum · doi:10.32615/bp.2019.026 · Cited by 21

The Role of Mitochondria in Statin-Induced Myopathy

Bell, G. M., Thoma, A., Hargreaves, I. P., & Lightfoot, A. P. (2024) · Drug Safety · doi:10.1007/s40264-024-01413-9 · Cited by 21

Hydrogen sulfide supplementation as a potential treatment for primary mitochondrial diseases

Slade, L., Deane, C. S., Szewczyk, N. J., Etheridge, T., & Whiteman, M. (2024) · Pharmacological Research · doi:10.1016/j.phrs.2024.107180 · Cited by 21

Age‐related increase of reactive oxygen generation in the brains of mammals and birds: Is reactive oxygen a signaling molecule to determine the aging process and life span?

Sasaki, T., Unno, K., Tahara, S., & Kaneko, T. (2010) · Geriatrics and gerontology international/Geriatrics & gerontology international · doi:10.1111/j.1447-0594.2010.00601.x · Cited by 21

Dissociative Electron Attachment to Anthralin to Model Its Biochemical Reactions

Pshenichnyuk, S. A., & Komolov, А. S. (2014) · The Journal of Physical Chemistry Letters · doi:10.1021/jz501523s · Cited by 21

Modeling the mechanism of metabolic oscillations in ischemic cardiac myocytes

Jafri, M. S., & Kotulska, M. (2006) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2006.05.007 · Cited by 22

2-deoxy-D-Glucose Synergizes with Doxorubicin or L-Buthionine Sulfoximine to Reduce Adhesion and Migration of Breast Cancer Cells

Mustafa, E. H., Mahmoud, H. T., Alhudhud, M., Abdalla, M. Y., Ahmad, I. M., Yasin, S. R., Elkarmi, A., & Tahtamouni, L. H. (2015) · Asian Pacific Journal of Cancer Prevention · doi:10.7314/apjcp.2015.16.8.3213 · Cited by 21

Female sex and Western-style diet protect mouse resistance arteries during acute oxidative stress

Norton, C. E., Jacobsen, N. L., Sinkler, S. Y., Manrique‐Acevedo, C., & Segal, S. S. (2019) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00342.2019 · Cited by 21

Mitochondrial Oxidative Phosphorylation Function and Mitophagy in Ischaemic/Reperfused Hearts from Control and High-Fat Diet Rats: Effects of Long-Term Melatonin Treatment

Dhanabalan, K., Mzezewa, S., Huisamen, B., & Lochner, A. (2020) · Cardiovascular Drugs and Therapy · doi:10.1007/s10557-020-06997-9 · Cited by 21

Knockout of VDAC1 in H9c2 Cells Promotes Oxidative Stress-Induced Cell Apoptosis through Decreased Mitochondrial Hexokinase II Binding and Enhanced Glycolytic Stress

Yang, M., Sun, J., Stowe, D. F., Tajkhorshid, E., Kwok, W.-M., & Camara, A. K. S. (2020) · Cellular Physiology and Biochemistry · doi:10.33594/000000274 · Cited by 21

Mitochondrial function is impaired in the primary visual cortex in an experimental glaucoma model

Arana, A. G. H., Vitar, R. M. L., Reides, C. G., Calabró, V., Marchini, T., Lerner, S. F., Evelson, P., & Ferreira, S. M. (2021) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2021.108815 · Cited by 21

Ameliorating reactive oxygen species-induced in vitro lipid peroxidation in brain, liver, mitochondria and DNA damage by Zingiber officinale Roscoe

Ajith, T. A. (2010) · Indian Journal of Clinical Biochemistry · doi:10.1007/s12291-010-0014-1 · Cited by 21

Herba Cistanche Extract Enhances Mitochondrial ATP Generation in Rat Hearts and H9c2 Cells

Leung, H. Y., & Ko, K. M. (2008) · Pharmaceutical Biology · doi:10.1080/13880200802055883 · Cited by 21

Uncoupling protein-2 up-regulation and enhanced cyanide toxicity are mediated by PPARα activation and oxidative stress

Zhang, X., Li, L., Prabhakaran, K., Zhang, L., Leavesley, H. B., Borowitz, J. L., & Isom, G. E. (2007) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2007.05.002 · Cited by 21

Oxylipins From Different Pathways Trigger Mitochondrial Stress Signaling Through Respiratory Complex III

Izquierdo, Y., Muñiz, L. M., Vicente, J., Kulasekaran, S., Aguilera, V., Sánchez, A. L., Martínez-Ayala, A., López, B., Cascón, T., & Castresana, C. (2021) · Frontiers in Plant Science · doi:10.3389/fpls.2021.705373 · Cited by 20

Decoding the crosstalk between mevalonate metabolism and T cell function

Kennewick, K. T., & Bensinger, S. J. (2023) · Immunological Reviews · doi:10.1111/imr.13200 · Cited by 20

STEAP Proteins: Roles in disease biology and potential for therapeutic intervention

Cai, Q., Jing, C., Wang, X., Xing, X., & Liu, W. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.142797 · Cited by 20

Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autophagy

Basak, B., & Holzbaur, E. L. F. (2025) · Nature Communications · doi:10.1038/s41467-025-62379-5 · Cited by 22

Loss of STAT3 in mouse embryonic fibroblasts reveals its Janus-like actions on mitochondrial function and cell viability

Zouein, F. A., Duhé, R. J., Arany, I., Shirey, K., Hosler, J. P., Liu, H., Saad, I., Kurdi, M., & Booz, G. W. (2014) · Cytokine · doi:10.1016/j.cyto.2013.12.006 · Cited by 20

In vivo efficacy of combination therapy with albendazole and atovaquone against primary hydatid cysts in mice

Enkai, S., Kouguchi, H., Inaoka, D. K., Irie, T., Yagi, K., & Kita, K. (2021) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-021-04230-5 · Cited by 20

Cytochrome c oxidase mediates labile iron level and radioresistance in glioblastoma

Ali, M. Y., Oliva, C. R., Flor, S., Goswami, P. C., & Griguer, C. E. (2022) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2022.04.012 · Cited by 21

Quercetin protects porcine oocytes from in vitro aging by reducing oxidative stress and maintaining the mitochondrial functions

Jiao, Y., Wang, Y., Jiang, T., Wen, K., Cong, P., Chen, Y., & He, Z. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.915898 · Cited by 20

Anticancer therapeutic effect of ginsenosides through mediating reactive oxygen species

Li, X., Cao, D., Sun, S., & Wang, Y. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1215020 · Cited by 21

Mitochondrial Dysfunction and Oxidative and Endoplasmic Reticulum Stress in Argyrophilic Grain Disease

Ilieva, E. V., Kichev, A., Naudí, A., Ferrer, I., Pamplona, R., & Portero‐Otín, M. (2011) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e31820f8765 · Cited by 20

The neurogenic basic helix-loop-helix transcription factor NeuroD6 enhances mitochondrial biogenesis and bioenergetics to confer tolerance of neuronal PC12-NeuroD6 cells to the mitochondrial stressor rotenone

Baxter, K. K., Uittenbogaard, M. N., & Chiaramello, A. (2012) · Experimental Cell Research · doi:10.1016/j.yexcr.2012.07.004 · Cited by 20

Some aspects of salinity responses in peppermint (Mentha × piperita L.) to NaCl treatment

Li, Z., Yang, H., Wu, X., Guo, K., & Li, J. (2014) · PROTOPLASMA · doi:10.1007/s00709-014-0728-7 · Cited by 20

Life-history Constraints on the Mechanisms that Control the Rate of ROS Production

Aledo, J. C. (2014) · Current Genomics · doi:10.2174/1389202915666140515230615 · Cited by 20

Impaired lymphocyte mitochondrial antioxidant defences in variegate porphyria are accompanied by more inducible reactive oxygen species production and DNA damage

Ferrer, M. D., Sureda, A., Tauler, P., Palacín, C., Tur, J. A., & Pons, A. (2010) · British Journal of Haematology · doi:10.1111/j.1365-2141.2010.08149.x · Cited by 20

Ghrelin Improves Antioxidant Defense in Blood and Brain in Normobaric Hypoxia in Adult Male Rats

Omrani, H., Alipour, M. R., & Mohaddes, G. (2015) · Advanced Pharmaceutical Bulletin · doi:10.15171/apb.2015.039 · Cited by 20

Low oxygen alters mitochondrial function and response to oxidative stress in human neural progenitor cells

Lages, Y., Nascimento, J. M., Lemos, G. G. M., Galina, A., Castilho, L. R., & Rehen, S. K. (2015) · PeerJ · doi:10.7717/peerj.1486 · Cited by 21

Responses of CHO cell lines to increased pCO2 at normal (37 °C) and reduced (33 °C) culture temperatures

Darja, O., Mandelc, S., Saša, S., Francky, A., Bojic, L., & Javornik, B. (2015) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2015.12.013 · Cited by 21

Acquired deficiency of tafazzin in the adult heart: Impact on mitochondrial function and response to cardiac injury

Szczepanek, K., Allegood, J. C., Aluri, H. S., Hu, Y., Chen, Q., & Lesnefsky, E. J. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2015.12.004 · Cited by 20

Cold Storage Exacerbates Renal and Mitochondrial Dysfunction Following Transplantation

Shrum, S., & MacMillan Crow, L. A. (2016) · Journal of Kidney · doi:10.4172/2472-1220.1000114 · Cited by 20

Comparison of the effects of MnO2-NPs and MnO2-MPs on mitochondrial complexes in different organs

Hafez, A. A., Naserzadeh, P., Mortazavian, A. M., Mehravi, B., Ashtari, K., Seydi, E., & Salimi, A. (2018) · Toxicology Mechanisms and Methods · doi:10.1080/15376516.2018.1512693 · Cited by 20

Neuroprotective effect of red quinoa seeds extract on scopolamine-induced declarative memory deficits in mice: The role of acetylcholinesterase and oxidative stress

de Souza, S. P., Roos, A. A., Gindri, A. L., Domingues, V. O., Ascari, J., & Guerra, G. P. (2020) · Journal of Functional Foods · doi:10.1016/j.jff.2020.103958 · Cited by 22

The Mitochondrial Permeability Transition Pore and its Role in Anaesthesia-Triggered Cellular Protection during Ischaemia-Reperfusion Injury

Andrews, D. T., Royse, C. F., & Royse, A. G. (2012) · Anaesthesia and Intensive Care · doi:10.1177/0310057x1204000106 · Cited by 20

PML/RARα fusion protein mediates the unique sensitivity to arsenic cytotoxicity in acute promyelocytic leukemia cells: Mechanisms involve the impairment of cAMP signaling and the aberrant regulation of NADPH oxidase

Li, L., Wang, J., Ye, R. D., Shi, G., Jin, H., Tang, X., & Yi, J. (2008) · Journal of Cellular Physiology · doi:10.1002/jcp.21523 · Cited by 20

Expression of hypoxia-inducible factor-1alpha (HIF-1alpha) related to oxidative stress in liver of rat-induced by systemic chronic normobaric hypoxia.

Jusman, S. W. A., Halim, A., Wanandi, S. I., & Sadikin, M. (2010) · PubMed · Cited by 20

Mitochondria‐Targeted Antioxidants and Uncouplers of Oxidative Phosphorylation in Treatment of the Systemic Inflammatory Response Syndrome (SIRS)

Zakharova, V., Pletjushkina, O. Y., Zinovkin, R. A., Popova, E. N., & Chernyak, B. V. (2016) · Journal of Cellular Physiology · doi:10.1002/jcp.25626 · Cited by 20

Mitochondrial complex II-derived superoxide is the primary source of mercury toxicity in barley root tip

Tamás, L., & Zelinová, V. (2016) · Journal of Plant Physiology · doi:10.1016/j.jplph.2016.10.014 · Cited by 20

Mitochondrial fragmentation affects neither the sensitivity to TNFα-induced apoptosis of Brucella-infected cells nor the intracellular replication of the bacteria

Lobet, E., Willemart, K., Ninane, N., Demazy, C., Sędzicki, J., Lelubre, C., Bolle, X. D., Renard, P., Raes, M. J., Dehio, C., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-23483-3 · Cited by 23

Role of p66shc in Renal Toxicity of Oleic Acid

Arany, I., Clark, J. S., Reed, D. K., Juncos, L. A., & Dixit, M. P. (2013) · American Journal of Nephrology · doi:10.1159/000354357 · Cited by 20

DNA damage response and neuroprotection

Kruman, I. I. (2007) · Frontiers in bioscience · doi:10.2741/2862 · Cited by 20

Cyanide-resistant respiration in Taenia crassiceps metacestode (cysticerci) is explained by the H2O2-producing side-reaction of respiratory complex I with O2

Mena, I. P. D. A., Rubio, M. E., Ramírez, J., Rendón, J. L., & Escamilla, J. E. (2005) · Parasitology International · doi:10.1016/j.parint.2005.04.003 · Cited by 20

The Role of Mitochondrial Dysfunction and Oxidative Stress in Women’s Reproductive Disorders: Implications for Polycystic Ovary Syndrome and Preeclampsia

Deer, E. M., LaMarca, B. B., Reckelhoff, J. F., Shawky, N. M., & Edwards, K. S. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26136439 · Cited by 19

α-Ketoglutarate for Preventing and Managing Intestinal Epithelial Dysfunction

Iniguez, A. B., Du, ‬., & Zhu, M. J. (2024) · Advances in Nutrition · doi:10.1016/j.advnut.2024.100200 · Cited by 21

Function and dysfunction of the oxidative phosphorylation system

Nijtmans, L. G. J., Ugalde, C., van den Heuvel, L. P., & Smeitink, J. A. M. (2004) · Topics in current genetics · doi:10.1007/b95715 · Cited by 21

Potassium loss is involved in tobacco cell death induced by palmitoleic acid and ceramide

Peters, J. S., & Chin, C. (2007) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2007.05.025 · Cited by 19

Immunoprotective Effect of Epigallocatechin-3-gallate on Oral Anticancer Drug-Induced α-Defensin Reduction in Caco-2 Cells

Takahashi, N., Kobayashi, M., Ogura, J., Yamaguchi, H., Satoh, T. K., Watanabe, K., & Iseki, K. (2014) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b13-00700 · Cited by 19

Disruption of alternative NAD(P)H dehydrogenases leads to decreased mitochondrial ROS in Neurospora crassa

Carneiro, P., Duarte, M., & Videira, A. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.10.492 · Cited by 19

Differential Expression of Adenine Nucleotide Converting Enzymes in Mitochondrial Intermembrane Space: A Potential Role of Adenylate Kinase Isozyme 2 in Neutrophil Differentiation

Tanimura, A., Horiguchi, T., Miyoshi, K., Hagita, H., & Noma, T. (2014) · PLoS ONE · doi:10.1371/journal.pone.0089916 · Cited by 19

Modulation of mitochondrial biomarkers by intermittent hypobaric hypoxia and aerobic exercise after eccentric exercise in trained rats

Rizo‐Roca, D., Ríos-Kristjánsson, J. G., Núñez-Espinosa, C. A., Alves, E. S., Magalhães, J., Ascensão, A. A. M. R., Pagés, T., Viscor, G., & Torrella, J. R. (2017) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2016-0526 · Cited by 19

Cardioprotective strategies preserve the stability of respiratory chain supercomplexes and reduce oxidative stress in reperfused ischemic hearts

Ramírez-Camacho, I., Correa, F., Hafidi, M. E., Silva‐Palacios, A., Ostolga-Chavarría, M., Esparza-Perusquía, M., Olvera-Sánchez, S., Flores-Herrera, Ó., & Zazueta, C. (2018) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.09.047 · Cited by 19

Capsaicin Alleviates the Deteriorative Mitochondrial Function by Upregulating 14-3-3η in Anoxic or Anoxic/Reoxygenated Cardiomyocytes

Yang, Q., Hu, T., Yang, B. J., Li, H., Chen, T., Yin, D., He, H., & He, M. L. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/1750289 · Cited by 19

Cardiomyocyte specific deletion of p53 decreases cell injury during ischemia-reperfusion: Role of Mitochondria

Chen, Q., Thompson, J., Hu, Y., & Lesnefsky, E. J. (2020) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2020.06.006 · Cited by 19

Urban air pollution induces alterations in redox metabolism and mitochondrial dysfunction in mice brain cortex

Calabró, V., Garcés, M., Cáceres, L., Magnani, N., Marchini, T., Freire, A., Vico, T. A., Martinefski, M., Vanasco, V., Tripodi, V. P., et al. (2021) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2021.108875 · Cited by 19

β-hydroxybutyrate accumulates in the rat heart during low-flow ischaemia with implications for functional recovery

Lindsay, R. T., Dieckmann, S. M., Krzyzanska, D., Manetta-Jones, D., West, J. A., Castro, C., Griffin, J. L., & Murray, A. J. (2021) · eLife · doi:10.7554/elife.71270 · Cited by 19

COX4-1 promotes mitochondrial supercomplex assembly and limits reactive oxide species production in radioresistant GBM

Oliva, C. R., Ali, M. Y., Flor, S., & Griguer, C. E. (2022) · Cell Stress · doi:10.15698/cst2022.04.266 · Cited by 19

Iron diminishes the in vitro biological effect of vanadium

Ghio, A. J., Stonehuerner, J., Soukup, J. M., Dailey, L. A., Kesic, M. J., & Cohen, M. D. (2015) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2015.03.008 · Cited by 19

Molecular modeling and experimental evidence for hypericin as a substrate for mitochondrial complex III; mitochondrial photodamage as demonstrated using specific inhibitors

Theodossiou, T. A., Papakyriakou, A., & Hothersall, J. S. (2008) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2008.09.015 · Cited by 19

Effects of cadmium on hepatocellular DNA damage, proto-oncogene expression and apoptosis in rats.

Yu, R., He, L., & Chen, X. (2007) · PubMed · Cited by 19

Photo-activation of the delocalized lipophilic cation D112 potentiates cancer selective ROS production and apoptosis

Yang, N., Weinfeld, M., Lemieux, H., Montpetit, B., & Goping, I. S. (2017) · Cell Death and Disease · doi:10.1038/cddis.2017.19 · Cited by 19

Mitochondrial modulation-induced activation of vagal sensory neuronal subsets by antimycin A, but not CCCP or rotenone, correlates with mitochondrial superoxide production

Stanford, K. R., & Taylor‐Clark, T. E. (2018) · PLoS ONE · doi:10.1371/journal.pone.0197106 · Cited by 20

Adenosine A1receptors and mitochondria: targets of remote ischemic preconditioning

Páez, D. T., Garcés, M., Calabró, V., Bin, E. P., D’Annunzio, V., Mauro, J. S. D., Marchini, T., Höcht, C., Evelson, P., Gelpi, R. J., et al. (2019) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00071.2018 · Cited by 19

Diuron in Water: Functional Toxicity and Intracellular Detoxification Patterns of Active Concentrations Assayed in Tandem by a Yeast-Based Probe

Dragone, R., Cheng, R., Grasso, G., & Frazzoli, C. (2015) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph120403731 · Cited by 19

Nicotinamide mononucleotide protects septic hearts in mice via preventing cyclophilin F modification and lysosomal dysfunction

Ni, R., Ji, X., Cao, T., Liu, X., Wang, C., Lu, C., Peng, A., Zhang, Z., Fan, G., Zhang, J., et al. (2024) · Acta Pharmacologica Sinica · doi:10.1038/s41401-024-01424-3 · Cited by 18

Chemotherapeutic agents induce mitochondrial superoxide production and toxicity but do not alter respiration in skeletal muscle in vitro

Rybalka, E., Timpani, C. A., Cheregi, B. D., Sorensen, J. C., Nurgali, K., & Hayes, A. (2017) · Mitochondrion · doi:10.1016/j.mito.2017.10.010 · Cited by 18

Chronic exposure to polluted urban air aggravates myocardial infarction by impaired cardiac mitochondrial function and dynamics

Marchini, T., Magnani, N., Garcés, M., Kelly, J., Paz, M. L., Cáceres, L., Calabró, V., Vitar, R. M. L., Caltana, L. R., Contin, M. D., et al. (2021) · Environmental Pollution · doi:10.1016/j.envpol.2021.118677 · Cited by 18

Hypoxia and its effect on the cellular system

Rahane, D., Dhingra, T., Chalavady, G., Datta, A., Ghosh, B., Rana, N., Borah, A., Saraf, S., & Bhattacharya, P. (2024) · Cell Biochemistry and Function · doi:10.1002/cbf.3940 · Cited by 20

Redox Regulation of Mitochondrial Potassium Channels Activity

Lewandowska, J., Kalenik, B., Wrzosek, A., & Szewczyk, A. M. (2024) · Antioxidants · doi:10.3390/antiox13040434 · Cited by 19

Opposite Production of Reactive Oxygen Species by Complexes I and III during Heart Ischemia/Reperfusion

Bopassa, J. C., Zilberstein, N., Toro, L., & Stefani, E. (2010) · Biophysical Journal · doi:10.1016/j.bpj.2009.12.3941

Critical role of mitochondrial ROS is dependent on their site of production on the electron transport chain in ischemic heart.

Madungwe, N. B., Zilberstein, N., Feng, Y., & Bopassa, J. C. (2016) · PubMed Central · Cited by 71

The Deleterious or Protective Action of ROS in the Heart Depends on their Production Site in the Mitochondrial Electron Transfer Chain

Bopassa, J. C., Zilberstein, N., Toro, L., & Stefani, E. (2012) · Biophysical Journal · doi:10.1016/j.bpj.2011.11.779

Complex I-mediated reactive oxygen species generation: modulation by cytochrome c and NAD(P)+ oxidation–reduction state

Kushnareva, Y., Murphy, A. N., & Andreyev, A. Y. (2002) · Biochemical Journal · doi:10.1042/bj20021121 · Cited by 696

Reactive oxygen species are generated by the respiratory complex II – evidence for lack of contribution of the reverse electron flow in complex I

Moreno‐Sánchez, R., Hernández‐Esquivel, L., Rivero‐Segura, N. A., Marín‐Hernández, A., Neuzil, J., Ralph, S. J., & Rodríguez‐Enríquez, S. (2013) · The FEBS Journal · doi:10.1111/febs.12086 · Cited by 100