Production of Reactive Oxygen Species by Mitochondria

Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria

Turrens, J. F., & Boveris, A. (1980) · Biochemical Journal · doi:10.1042/bj1910421 · Cited by 1,601

Topology of superoxide production from different sites in the mitochondrial electron transport chain

St-Pierre, J., Buckingham, J. A., Roebuck, S. J., & Brand, M. D. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m207217200 · Cited by 1,545

Complete Structure of the 11-Subunit Bovine Mitochondrial Cytochrome bc 1 Complex

Iwata, S., Lee, J. W., Okada, K., Lee, J. K., Iwata, M., Rasmussen, B., Link, T. A., Ramaswamy, S., & Jap, B. K. (1998) · Science · doi:10.1126/science.281.5373.64 · Cited by 1,253

Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria

Turrens, J. F., Alexandre, A., & Lehninger, A. L. (1985) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(85)90293-0 · Cited by 1,214

Oxygen activation and the conservation of energy in cell respiration

Babcock, Ǵ., & Wikström, M. K. F. (1992) · Nature · doi:10.1038/356301a0 · Cited by 1,126

Biochemical properties of subsarcolemmal and interfibrillar mitochondria isolated from rat cardiac muscle

Palmer, J. W., Tandler, B., & Hoppel, C. L. (1977) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)75283-1 · Cited by 830

Mitochondrial Dysfunction in Cardiac Disease: Ischemia–Reperfusion, Aging, and Heart Failure

Lesnefsky, E. J., Moghaddas, S., Tandler, B., Kerner, J., & Hoppel, C. L. (2001) · Journal of Molecular and Cellular Cardiology · doi:10.1006/jmcc.2001.1378 · Cited by 719

Voltage-dependent anion channels control the release of the superoxide anion from mitochondria to cytosol

Han, D., Antunes, F., Canali, R., Rettori, D., & Cadenas, E. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m210269200 · Cited by 711

The protonmotive Q cycle. Energy transduction by coupling of proton translocation to electron transfer by the cytochrome bc1 complex.

Trumpower, B. L. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)38410-8 · Cited by 598

Detection of catalase in rat heart mitochondria.

Radi, R., Turrens, J. F., Chang, L. Y., Bush, K. M., Crapo, J. D., & Freeman, B. A. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)54740-2 · Cited by 573

Production of Reactive Oxygen Species and Its Implication in Human Diseases

Mani, S. (2014) · Springer eBooks · doi:10.1007/978-81-322-2035-0_1 · Cited by 36

Cardioprotection by volatile anesthetics: new applications for old drugs?

Pratt, P. F., Wang, C., Weihrauch, D., Bienengraeber, M. W., Kersten, J. R., Pagel, P. S., & Warltier, D. C. (2006) · Current Opinion in Anaesthesiology · doi:10.1097/01.aco.0000236139.31099.b5 · Cited by 36

The responses of HT22 cells to the blockade of mitochondrial complexes and potential protective effect of selenium supplementation

Panee, J., Liu, W., Nakamura, K., & Berry, M. J. (2007) · International Journal of Biological Sciences · doi:10.7150/ijbs.3.335 · Cited by 38

Vascular smooth muscle mitochondria at the cross roads of Ca2+ regulation

Poburko, D., Lee, C., & van Breemen, C. (2004) · Cell Calcium · doi:10.1016/j.ceca.2004.01.020 · Cited by 36

Fast-Twitch Glycolytic Skeletal Muscle Is Predisposed to Age-Induced Impairments in Mitochondrial Function

Jacobs, R. A., Díaz, V., Soldini, L., Haider, T., Thomassen, M., Nordsborg, N. B., Gassmann, M., & Lundby, C. (2013) · The Journals of Gerontology Series A · doi:10.1093/gerona/gls335 · Cited by 37

Glyoxal toxicity in isolated rat liver mitochondria

Goudarzi, M., Kalantari‬, H., & Rezaei, M. (2017) · Human & Experimental Toxicology · doi:10.1177/0960327117715900 · Cited by 36

Direct, DNA Pol-γ-Independent Effects of Nucleoside Reverse Transcriptase Inhibitors on Mitochondrial Bioenergetics

Lund, K. C., & Wallace, K. B. (2004) · Cardiovascular Toxicology · doi:10.1385/ct:4:3:217 · Cited by 36

Zidovudine (AZT) and hepatic lipid accumulation: implication of inflammation, oxidative and endoplasmic reticulum stress mediators

Banerjee, A., Abdelmegeed, M. A., Jang, S., & Song, B.-J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0076850 · Cited by 35

Impairment of pH gradient and membrane potential mediates redox dysfunction in the mitochondria of the post-ischemic heart

Kang, P. T., Chen, C., Lin, P., Chilian, W. M., & Chen, Y. (2017) · Basic Research in Cardiology · doi:10.1007/s00395-017-0626-1 · Cited by 35

Integrated Approach Reveals Role of Mitochondrial Germ-Line Mutation F18L in Respiratory Chain, Oxidative Alterations, Drug Sensitivity, and Patient Prognosis in Glioblastoma

Keatley, K., Stromei-Cleroux, S., Wiltshire, T., Rajala, N. K. M., Burton, G., Holt, W. V., Littlewood, D. T. J., Briscoe, A. G., Jung, J., Ashkan, K., et al. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20133364 · Cited by 35

NLRP3-mediated inflammation in cardio-oncology: sterile yet harmful

Mauro, A. G., Mezzaroma, E., Toldo, S. A., Meléndez, G. C., Franco, R. L., Lesnefsky, E. J., Abbate, A., Hundley, W. G., & Salloum, F. N. (2022) · Translational research · doi:10.1016/j.trsl.2022.08.004 · Cited by 35

Protective Effects of Melatonin Against Zearalenone Toxicity on Porcine Embryos in vitro

Xu, Y. Q., Zhang, K., Sun, M., Lan, M., Wan, X., Zhang, Y., & Sun, S. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.00327 · Cited by 35

The Role of Mitochondrial and Endoplasmic Reticulum Reactive Oxygen Species Production in Models of Perinatal Brain Injury

Singh‐Mallah, G., Nair, S., Sandberg, M., Mallard, C. E., & Hagberg, H. (2019) · Antioxidants and Redox Signaling · doi:10.1089/ars.2019.7779 · Cited by 35

The mechanism of damage in the midgut of Bombyx mori after chlorantraniliprole exposure

Hu, J., Li, M., Lu, Z., Mao, T., Chen, J., Wang, H., Qu, J., Fang, Y., Cheng, X., Li, J., et al. (2019) · Ecotoxicology · doi:10.1007/s10646-019-02089-z · Cited by 35

Effects of copper and temperature on heart mitochondrial hydrogen peroxide production

Isei, M. O., & Kamunde, C. (2019) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2019.12.006 · Cited by 35

Omics Integration for Mitochondria Systems Biology

Hu, X. Y., Go, Y., & Jones, D. P. (2019) · Antioxidants and Redox Signaling · doi:10.1089/ars.2019.8006 · Cited by 35

What is the Role of Lipid Membrane-embedded Quinones in Mitochondria and Chloroplasts? Chemiosmotic Q-cycle versus Murburn Reaction Perspective

Manoj, K. M., Gideon, D. A., & Parashar, A. (2020) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-020-00945-y · Cited by 36

Insights into the drug screening approaches in leishmaniasis

Gopu, B., Kour, P., Pandian, R., & Singh, K. (2022) · International Immunopharmacology · doi:10.1016/j.intimp.2022.109591 · Cited by 35

The proline metabolism intermediate Δ1‐pyrroline‐5‐carboxylate directly inhibits the mitochondrial respiration in budding yeast

Nishimura, A., Nasuno, R., & Takagi, H. (2012) · FEBS Letters · doi:10.1016/j.febslet.2012.05.056 · Cited by 35

Resveratrol affects differently rat liver and brain mitochondrial bioenergetics and oxidative stress in vitro: Investigation of the role of gender

Moreira, A. C., Silva, A. M., Santos, M. S., & Sardão, V. A. (2012) · Food and Chemical Toxicology · doi:10.1016/j.fct.2012.11.031 · Cited by 35

Interactions of copper and thermal stress on mitochondrial bioenergetics in rainbow trout, Oncorhynchus mykiss

Sappal, R., MacDonald, N., Fast, M. D., Stevens, D., Kibenge, F., Siah, A., & Kamunde, C. (2014) · Aquatic Toxicology · doi:10.1016/j.aquatox.2014.09.007 · Cited by 35

Protective effects of erdosteine on rotenone-induced oxidant injury in liver tissue

Terzi, A., Iraz, M., Şahin, Ş., İlhan, A., İdiz, N., & Fadıllıoğlu, E. (2004) · Toxicology and Industrial Health · doi:10.1191/0748233704th208oa · Cited by 35

Analysis of mitochondrial generation and release of reactive oxygen species

Mattiasson, G. (2004) · Cytometry Part A · doi:10.1002/cyto.a.20089 · Cited by 35

KBP–cytoskeleton interactions underlie developmental anomalies in Goldberg–Shprintzen syndrome

Drévillon, L., Mégarbané, A., Demeer, B., Matar, C., Bénit, P., Briand‐Suleau, A., Bodereau, V., Ghoumid, J., Nasser, M., Decrouy, X., et al. (2013) · Human Molecular Genetics · doi:10.1093/hmg/ddt083 · Cited by 35

Alterations in mitochondrial respiration and reactive oxygen species in patients poisoned with carbon monoxide treated with hyperbaric oxygen

Jang, D. H., Khatri, U. G., Shortal, B. P., Kelly, M., Hardy, K. R., Lambert, D. S., & Eckmann, D. M. (2018) · Intensive Care Medicine Experimental · doi:10.1186/s40635-018-0169-2 · Cited by 35

Public and private mechanisms of life extension in Caenorhabditis elegans

Houthoofd, K., & Vanfleteren, J. R. (2007) · Molecular Genetics and Genomics · doi:10.1007/s00438-007-0225-1 · Cited by 35

Stimulation of superoxide production increases fungicidal action of miconazole against Candida albicans biofilms

De Cremer, K., De Brucker, K., Staes, I., Peeters, A., Van den Driessche, F., Coenye, T., Cammue, B. P. A., & Thevissen, K. (2016) · Scientific Reports · doi:10.1038/srep27463 · Cited by 34

Quantitative Redox Proteomics: The NOxICAT Method

Lindemann, C., & Leichert, L. I. O. (2012) · Methods in molecular biology · doi:10.1007/978-1-61779-885-6_24 · Cited by 34

Isolating the segment of the mitochondrial electron transport chain responsible for mitochondrial damage during cardiac ischemia

Chen, Q., Yin, G., Stewart, S., Hu, Y., & Lesnefsky, E. J. (2010) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2010.05.137 · Cited by 34

Photoprotective effect of Astragalus membranaceus polysaccharide on UVA-induced damage in HaCaT cells

Li, Q., Wang, D., Bai, D., Cai, C., Li, J., Yan, C., Zhang, S., Wu, Z., Hao, J., & Yu, G. (2020) · PLoS ONE · doi:10.1371/journal.pone.0235515 · Cited by 34

Clinical Relevance of lncRNA and Mitochondrial Targeted Antioxidants as Therapeutic Options in Regulating Oxidative Stress and Mitochondrial Function in Vascular Complications of Diabetes

Pant, T., Uche, N., Juric, M., & Bosnjak, Z. J. (2023) · Antioxidants · doi:10.3390/antiox12040898 · Cited by 37

Role of Reactive Oxygen Species in the Radiation Response of Human Hematopoietic Stem/Progenitor Cells

Yamaguchi, M., & Kashiwakura, I. (2013) · PLoS ONE · doi:10.1371/journal.pone.0070503 · Cited by 38

Methylene Blue Protects Astrocytes against Glucose Oxygen Deprivation by Improving Cellular Respiration

Choudhury, G. R., Winters, A., Rich, R. M., Ryou, M., Gryczynski, Z. K., Yuan, F., Yang, S., & Liu, R. (2015) · PLoS ONE · doi:10.1371/journal.pone.0123096 · Cited by 34

The tumor suppressor WW domain-containing oxidoreductase modulates cell metabolism

Abu‐Remaileh, M., & Aqeilan, R. I. (2014) · Experimental Biology and Medicine · doi:10.1177/1535370214561956 · Cited by 33

Cellular Adaptation to Anthrax Lethal Toxin-Induced Mitochondrial Cholesterol Enrichment, Hyperpolarization, and Reactive Oxygen Species Generation through Downregulating MLN64 in Macrophages

Ha, S.-D., Park, S., Han, C. Y., Nguyen, M. L., & Kim, S. O. (2012) · Molecular and Cellular Biology · doi:10.1128/mcb.00494-12 · Cited by 36

Direct oxidative pathway from amplex red to resorufin revealed by in situ confocal imaging

Lefrançois, P., Vajrala, V. S., Bonifas, I., Goudeau, B., Doneux, T., Bouffier, L., & Arbault, S. (2016) · Physical Chemistry Chemical Physics · doi:10.1039/c6cp04438g · Cited by 33

Mitochondrial Uptake and Accumulation of Vitamin C: What Can We Learn from Cell Culture Studies?

Cantoni, O., Guidarelli, A., & Fiorani, M. (2017) · Antioxidants and Redox Signaling · doi:10.1089/ars.2017.7253 · Cited by 33

Aedes aegypti microRNA, miR-2944b-5p interacts with 3'UTR of chikungunya virus and cellular target vps-13 to regulate viral replication

Dubey, S., Shrinet, J., & Sunil, S. (2019) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0007429 · Cited by 33

Identification of two mitochondrial-targeting cyclometalated iridium(III) complexes as potent anti-glioma stem cells agents

Peng, W., Hegazy, A. M., Jiang, N., Chen, X., Qi, H., Zhao, X., Pu, J., Ye, R., & Li, R. (2019) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2019.110909 · Cited by 34

NADPH oxidase and mitochondria are relevant sources of superoxide anion in the oxinflammatory response of macrophages exposed to airborne particulate matter

Cáceres, L., Paz, M. L., Garcés, M., Calabró, V., Magnani, N., Martinefski, M., Adami, P. V. M., Caltana, L. R., Tasat, D. R., Morelli, L., et al. (2020) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2020.111186 · Cited by 34

Deguelin targets multiple oncogenic signaling pathways to combat human malignancies

Tuli, H. S., Mittal, S., Loka, M., Aggarwal, V., Aggarwal, D., Masurkar, A., Kaur, G., Varol, M., Sak, K., Kumar, M., et al. (2021) · Pharmacological Research · doi:10.1016/j.phrs.2021.105487 · Cited by 33

Mitochondrial Regulation of Diabetic Kidney Disease

Galvan, D. L., Mise, K., & Danesh, F. R. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.745279 · Cited by 35

Towards a molecular mechanism underlying mitochondrial protein import through the TOM and TIM23 complexes

Ford, H. C., Allen, W. J., Pereira, G. C., Liu, X., Dillingham, M. S., & Collinson, I. R. (2022) · eLife · doi:10.7554/elife.75426 · Cited by 33

Sono-ReCORMs for synergetic sonodynamic-gas therapy of hypoxic tumor

Li, Y., Lu, N., Lin, Q., Wang, H., Liang, Z., Lü, Y., & Zhang, P. (2022) · Chinese Chemical Letters · doi:10.1016/j.cclet.2022.06.076 · Cited by 33

Analysis of proteome changes in doxorubicin-treated adult rat cardiomyocyte

Kumar, S. N., Konorev, E. A., Aggarwal, D., & Kalyanaraman, B. (2011) · Journal of Proteomics · doi:10.1016/j.jprot.2011.02.013 · Cited by 33

Bioenergetic remodeling during cellular differentiation: changes in cytochrome c oxidase regulation do not affect the metabolic phenotype

Lyons, C. N., Leary, S. C., & Moyes, C. D. (2004) · Biochemistry and Cell Biology · doi:10.1139/o04-040 · Cited by 33

Dissociative Electron Attachment to Resveratrol as a Likely Pathway for Generation of the H2 Antioxidant Species Inside Mitochondria

Pshenichnyuk, S. A., & Komolov, А. S. (2015) · The Journal of Physical Chemistry Letters · doi:10.1021/acs.jpclett.5b00368 · Cited by 33

Alterations of energy metabolism and glutathione levels of HL-60 cells induced by methacrylates present in composite resins

Nocca, G., Palma, F. D., Minucci, A., Sole, P. D., Martorana, G. E., Callà, C. A. M., Morlacchi, C., Gozzo, M. L., Gambarini, G., Chimenti, C., et al. (2006) · Journal of Dentistry · doi:10.1016/j.jdent.2006.07.008 · Cited by 33

Enhancement of Cyanide-Induced Mitochondrial Dysfunction and Cortical Cell Necrosis by Uncoupling Protein-2

Li, L., Prabhakaran, K., Mills, E., Borowitz, J. L., & Isom, G. E. (2005) · Toxicological Sciences · doi:10.1093/toxsci/kfi164 · Cited by 33

Decreases in mitochondrial reactive oxygen species initiate GABA A receptor‐mediated electrical suppression in anoxia‐tolerant turtle neurons

Hogg, D. W., Pamenter, M. E., Dukoff, D. J., & Buck, L. T. (2015) · The Journal of Physiology · doi:10.1113/jp270474 · Cited by 36

Systems-level analyses dissociate genetic regulators of reactive oxygen species and energy production

Bennett, N. K., Lee, M., Orr, A. L., & Nakamura, K. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2307904121 · Cited by 32

Mitochondrial electron transport chain functions in long-lived Ames dwarf mice

Choksi, K. B., Nuss, J. E., DeFord, J. H., & Papaconstantinou, J. (2011) · Aging · doi:10.18632/aging.100357 · Cited by 32

Recurrent inhibition of mitochondrial complex III induces chronic pulmonary vasoconstriction and glycolytic switch in the rat lung

Rafikova, O., Srivastava, A., Desai, A. A., Rafikov, R., & Tofovic, S. P. (2018) · Respiratory Research · doi:10.1186/s12931-018-0776-1 · Cited by 33

Mitochondrial Involvement in the Adaptive Response to Chronic Exposure to Environmental Pollutants and High-Fat Feeding in a Rat Liver and Testis

Migliaccio, V., Gregorio, I. D., Putti, R., & Lionetti, L. (2019) · Cells · doi:10.3390/cells8080834 · Cited by 32

Fluoride-induced renal dysfunction via respiratory chain complex abnormal expression and fusion elevation in mice

Wang, H., Zhu, S.-Q., Liu, J., Miao, C.-Y., Zhang, Y., & Zhou, B.-H. (2019) · Chemosphere · doi:10.1016/j.chemosphere.2019.124607 · Cited by 32

Reactive oxygen species production induced by pore opening in cardiac mitochondria: The role of complex III

Kôrge, P., Calmettes, G., John, S., & Weiss, J. N. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.768317 · Cited by 32

4E-BP1 counteracts human mesenchymal stem cell senescence via maintaining mitochondrial homeostasis

He, Y., Ji, Q., Wu, Z., Cai, Y., Yin, J. B., Zhang, Y., Zhang, S., Liu, X., Zhang, W., Liu, G., et al. (2022) · Protein & Cell · doi:10.1093/procel/pwac037 · Cited by 32

The mitochondrial respiratory chain has a critical role in the antiviral process in Coxsackievirus B3-induced myocarditis

Ebermann, L., Wika, S., Klumpe, I., Hammer, E., Klingel, K., Laßner, D., Völker, U., Erben, U., Zeichhardt, H., Schultheiß, H., et al. (2011) · Laboratory Investigation · doi:10.1038/labinvest.2011.145 · Cited by 32

Mitochondrial genome function and maternal inheritance

Allen, J. F., & de Paula, W. B. M. (2013) · Biochemical Society Transactions · doi:10.1042/bst20130106 · Cited by 33

Cardiac Aging and Insulin Resistance: Could Insulin/Insulin-Like Growth Factor (IGF) Signaling be used as a Therapeutic Target?

Boudina, S. (2013) · Current Pharmaceutical Design · doi:10.2174/1381612811319320004 · Cited by 32

Real-time chemiluminescent imaging and detection of reactive oxygen species generated in the UVB-exposed human skin equivalent model

Yasui, H., Hakozaki, T., Date, A., Yoshii, T., & Sakurai, H. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.06.046 · Cited by 32

Apolipoprotein A1 Regulates Coenzyme Q10 Absorption, Mitochondrial Function, and Infarct Size in a Mouse Model of Myocardial Infarction

Dadabayev, A. R., Yin, G., Latchoumycandane, C., McIntyre, T. M., Lesnefsky, E. J., & Penn, M. S. (2014) · Journal of Nutrition · doi:10.3945/jn.113.184291 · Cited by 32

Role of mitochondrial permeability transition in taurine deficiency-induced apoptosis.

Jong, C. J., Azuma, J., & Schaffer, S. W. (2011) · PubMed Central · Cited by 32

Mitochondrial oxidative stress and dysfunction induced by single‐ and multiwall carbon nanotubes: A comparative study

Ghanbari, F., Nasarzadeh, P., Seydi, E., Ghasemi, A., Joghataei, M. T., Ashtari, K., & Akbari, M. (2017) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.36063 · Cited by 32

Molecular effects of a variable environment on Sydney rock oysters, Saccostrea glomerata: Thermal and low salinity stress, and their synergistic effect

Ertl, N. G., O’Connor, W. A., & Elizur, A. (2018) · Marine Genomics · doi:10.1016/j.margen.2018.10.003 · Cited by 35

ERR1- and PGC1α-associated mitochondrial alterations correlate with pan-cancer disparity in African Americans

Piyarathna, D. W. B., Balasubramanian, A., Arnold, J. M., Lloyd, S. M., Karanam, B., Castro, P. D., Ittmann, M., Putluri, N., Navone, N. M., Jones, J. A., et al. (2019) · Journal of Clinical Investigation · doi:10.1172/jci127579 · Cited by 32

Aging‐associated atrial fibrillation: A comprehensive review focusing on the potential mechanisms

Wang, M., Hou, C., Jia, F., Zhong, C., Xue, C., & Li, J. (2024) · Aging Cell · doi:10.1111/acel.14309 · Cited by 33

‘Yang-Invigorating’ Chinese Tonic Herbs Enhance Mitochondrial ATP Generation in H9c2 Cardiomyocytes

Wong, H. S., Leung, H. Y., & Ko, K. M. (2011) · Chinese Medicine · doi:10.4236/cm.2011.21001 · Cited by 31

Scavenging ROS dramatically increases NMDA receptor whole cell currents in painted turtle cortical neurons

Dukoff, D. J., Hogg, D. W., Hawrsyh, P. J., & Buck, L. T. (2014) · Journal of Experimental Biology · doi:10.1242/jeb.105825 · Cited by 31

Influence of follicle size on bovine oocyte lipid composition, follicular metabolic and stress markers, embryo development and blastocyst lipid content

Annes, K., Muller, D. B., Vilela, J. A. P., Valente, R. S., Caetano, D. P., Cibin, F. W. S., Milazzotto, M. P., Mesquita, F. S., Belaz, K. R. A., Eberlin, M. N., et al. (2018) · Reproduction Fertility and Development · doi:10.1071/rd18109 · Cited by 31

An evolutionary, or “Mitocentric” perspective on cellular function and disease

Brown, J. A., Sammy, M. J., & Ballinger, S. W. (2020) · Redox Biology · doi:10.1016/j.redox.2020.101568 · Cited by 31

Sodium fluoride causes oxidative damage to silkworm (Bombyx mori) testis by affecting the oxidative phosphorylation pathway

Tang, W., Xiao, Y., Long, Y., Li, Y., Peng, F., Zhu, C., He, T., Lou, D., & Zhu, Y. (2021) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2021.112229 · Cited by 31

Age-related changes in H2O2 production and bioenergetics in rat brain synaptosomes

Kilbride, S. M., Telford, J. E., & Davey, G. P. (2008) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2008.05.445 · Cited by 31

Emerging role of innate immunity in organ transplantation part III: the quest for transplant tolerance via prevention of oxidative allograft injury and its consequences

Land, W. G. (2011) · Transplantation Reviews · doi:10.1016/j.trre.2011.07.001 · Cited by 31

Myocardial triggers involved in activation of remote ischaemic preconditioning

Donato, M., Goyeneche, M. A., Garcés, M., Marchini, T., Pérez, V., Mauro, J. S. D., Höcht, C., Rodrı́guez, M., Evelson, P., & Gelpi, R. J. (2016) · Experimental Physiology · doi:10.1113/ep085535 · Cited by 31

Acute exposure to a Mn/Zn ethylene-bis-dithiocarbamate fungicide leads to mitochondrial dysfunction and increased reactive oxygen species production in Caenorhabditis elegans

Todt, C. E., Bailey, D. C., Pressley, A. S., Orfield, S. E., Denney, R. D., Snapp, I. B., Negga, R., Bailey, A. C., Montgomery, K. M., Traynor, W. L., et al. (2016) · NeuroToxicology · doi:10.1016/j.neuro.2016.09.011 · Cited by 31

SIRT1/PGC-1

Rasouri, S., Lagouge, M., & Auwerx, J. H. (2007) · médecine/sciences · doi:10.1051/medsci/20072310840 · Cited by 33

Intermediary metabolism and fatty acid oxidation: novel targets of electron transport chain-driven injury during ischemia and reperfusion

Chen, Q., Younus, M., Thompson, J., Hu, Y., Hollander, J. M., & Lesnefsky, E. J. (2017) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00531.2017 · Cited by 30

Targeting ER stress and calpain activation to reverse age-dependent mitochondrial damage in the heart

Thompson, J., Maceyka, M. W., & Chen, Q. (2020) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2020.111380 · Cited by 30

RORα Suppresses Cancer-Associated Inflammation by Repressing Respiratory Complex I-Dependent ROS Generation

Mao, W., Xiong, G., Wu, Y., Wang, C., Clair, D. K. S., Li, J., & Xu, R. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms221910665 · Cited by 30

β2-adrenoceptor agonist-evoked reactive oxygen species generation in mouse atria: implication in delayed inotropic effect

Odnoshivkina, Y. G., Sytchev, V. I., Faritovich, N. L., Giniatullin, А. R., Zefirov, A. L., & Petrov, A. M. (2015) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2015.08.020 · Cited by 30

Protective effect of unsymmetrical dichalcogenide, a novel antioxidant agent, in vitro and an in vivo model of brain oxidative damage

Prigol, M., Wilhelm, E. A., Schneider, C. C., & Nogueira, C. W. (2008) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2008.07.006 · Cited by 30

Lipopolysaccharide-Induced Weakness in the Preterm Diaphragm Is Associated with Mitochondrial Electron Transport Chain Dysfunction and Oxidative Stress

Song, Y., Pinniger, G. J., Bakker, A. J., Moss, T. J. M., Noble, P. B., Berry, C. A., & Pillow, J. J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0073457 · Cited by 30

Huperzine A attenuates mitochondrial dysfunction after middle cerebral artery occlusion in rats

Zheng, C. Y., Zhang, H., & Tang, X. C. (2008) · Journal of Neuroscience Research · doi:10.1002/jnr.21681 · Cited by 30

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Prabhakaran, K., Li, L., Mills, E., Borowitz, J. L., & Isom, G. E. (2005) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.105.088625 · Cited by 30

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Clement, H., Vazquez-Costa, J. F., Sommer, O., Heiser, P., Morawietz, H., Hopt, U. T., Schulz, E., & von Dobschütz, E. (2009) · Journal of Neural Transmission · doi:10.1007/s00702-009-0327-5 · Cited by 29

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Shaki, F., Pourahmad, J., Hosseini, M., & Ghazi‐Khansari, M. (2012) · Research in Pharmaceutical Sciences · Cited by 29

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