Identification and Characterization of E2F7, a Novel Mammalian E2F Family Member Capable of Blocking Cellular Proliferation

The regulation of E2F by pRB-family proteins.

Dyson, N. (1998) · Genes & Development · doi:10.1101/gad.12.15.2245 · Cited by 2,317

Production of high-titer helper-free retroviruses by transient transfection.

Pear, W. S., Nolan, G. P., Scott, M. L., & Baltimore, D. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.18.8392 · Cited by 2,267

Sibling rivalry in the E2F family

Trimarchi, J. M., & Lees, J. A. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm714 · Cited by 1,158

A Complex with Chromatin Modifiers That Occupies E2F- and Myc-Responsive Genes in G 0 Cells

Ogawa, H., Ishiguro, K., Gaubatz, S., Livingston, D. M., & Nakatani, Y. (2002) · Science · doi:10.1126/science.1069861 · Cited by 785

The E2F1–3 transcription factors are essential for cellular proliferation

Wu, L., Timmers, C. D., Maiti, B., Saavedra, H. I., Sang, L., Chong, G. T., Nuckolls, F., Giangrande, P. H., Wright, F. A., Field, S. J., et al. (2001) · Nature · doi:10.1038/35106593 · Cited by 620

Analysis of Chromatin Structure byin VivoFormaldehyde Cross-Linking

Orlando, V., Strutt, H. L., & Paro, R. (1997) · Methods · doi:10.1006/meth.1996.0407 · Cited by 607

Toward an understanding of the functional complexity of the E2F and retinoblastoma families.

Nevins, J. R. (1998) · PubMed · Cited by 514

E2F3 activity is regulated during the cell cycle and is required for the induction of S phasePreprint

Leone, G. W., DeGregori, J. V., Yan, Z., Jakoi, L., Ishida, S., Williams, R. S., & Nevins, J. R. (1998) · Genes & Development · doi:10.1101/gad.12.14.2120 · Cited by 400

Emerging roles for E2F: Beyond the G1/S transition and DNA replication

Cam, H. P., & Dynlacht, B. D. (2003) · Cancer Cell · doi:10.1016/s1535-6108(03)00080-1 · Cited by 344

Role of an adenovirus E2 promoter binding factor in E1A-mediated coordinate gene control.

Kovesdi, I., Reichel, R., & Nevins, J. R. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.8.2180 · Cited by 278

Hox and a Newly Identified E2F Co-repress Cell Death in Caenorhabditis elegans

Winn, J., Carter, M., Avery, L., & Cameron, S. (2011) · Genetics · doi:10.1534/genetics.111.128421 · Cited by 35

Characterization of the mechanism by which the RB/E2F pathway controls expression of the cancer genomic DNA deaminase APOBEC3B

Roelofs, P. A., Goh, C. Y., Chua, B. H., Jarvis, M. C., Stewart, T. A., McCann, J. L., McDougle, R. M., Carpenter, M. A., Martens, J. W. M., Span, P. N., et al. (2020) · eLife · doi:10.7554/elife.61287 · Cited by 33

A transcriptomic computational analysis of mastic oil-treated Lewis lung carcinomas reveals molecular mechanisms targeting tumor cell growth and survival

Moulos, P., Papadodima, O., Chatziioannou, A. A., Loutrari, H. V., Roussos, C., & Kolisis, F. N. (2009) · BMC Medical Genomics · doi:10.1186/1755-8794-2-68 · Cited by 34

Feedback regulation between atypical E2Fs and APC/CCdh1 coordinates cell cycle progression

Boekhout, M., Yuan, R.-X., Wondergem, A. P., Segeren, H. A., Liere, E. A., Awol, N., Jansen, I., Wolthuis, R., de Bruin, A., & Westendorp, B. (2016) · EMBO Reports · doi:10.15252/embr.201540984 · Cited by 36

MicroRNA Mediated Chemokine Responses in Human Airway Smooth Muscle Cells

Dileepan, M., Sarver, A. E., Sriramarao, P., Panettieri, R. A., Subramanian, S., & Kannan, M. (2016) · PLoS ONE · doi:10.1371/journal.pone.0150842 · Cited by 34

Chk1 and 14‐3‐3 proteins inhibit atypical E2Fs to prevent a permanent cell cycle arrest

Yuan, R., Vos, H. R., van Es, R. M., Chen, J., Burgering, B. M. T., Westendorp, B., & de Bruin, A. (2018) · The EMBO Journal · doi:10.15252/embj.201797877 · Cited by 37

E2F7, regulated by miR‑30c, inhibits apoptosis and promotes cell cycle of prostate cancer cells

Wang, Y., Pei, X., Xu, P., Tan, Z., Zhu, Z., Zhang, G., Jiang, Z., & Deng, Z. (2020) · Oncology Reports · doi:10.3892/or.2020.7659 · Cited by 33

Host Cell Factor-1 and E2F4 Interact Via Multiple Determinants in Each Protein

Knez, J., Piluso, D., Bilan, P. T., & Capone, J. P. (2006) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-006-9122-x · Cited by 35

A combinatorial mechanism for determining the specificity of E2F activation and repression

Freedman, J. A., Chang, J. T., Jakoi, L., & Nevins, J. R. (2009) · Oncogene · doi:10.1038/onc.2009.153 · Cited by 32

RBM38 Is a Direct Transcriptional Target of E2F1 that Limits E2F1-Induced Proliferation

Feldstein, O., Ben‐Hamo, R., Bashari, D., Efroni, S., & Ginsberg, D. (2012) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-12-0331 · Cited by 34

Silencing of the Meiotic Genes SMC1β and STAG3 in Somatic Cells by E2F6

Storre, J., Schäfer, A., Reichert, N., Barbero, J. L., Hauser, S., Eilers, M., & Gaubatz, S. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m506797200 · Cited by 35

ERα and ERβ Homodimers in the Same Cellular Context Regulate Distinct Transcriptomes and Functions

Song, D., He, H., Indukuri, R., Huang, Z., Stepanauskaitė, L., Sinha, I., Haldosén, L.-A., Zhao, C., & Williams, C. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.930227 · Cited by 32

Signalling In The Epidermis: The E2f Cell Cycle Regulatory Pathway In Epidermal Morphogenesis, Regeneration And Transformation

Ivanova, I. A., D’Souza, S. J. A., & Dagnino, L. (2005) · International Journal of Biological Sciences · doi:10.7150/ijbs.1.87 · Cited by 32

High Incidence of Thymic Epithelial Tumors in E2F2 Transgenic Mice

Scheijen, B., Bronk, M., van der Meer, T., de Jong, D., & Bernards, R. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m313682200 · Cited by 32

E2f6 and Bmi1 cooperate in axial skeletal development

Courel, M., Friesenhahn, L., & Lees, J. A. (2008) · Developmental Dynamics · doi:10.1002/dvdy.21516 · Cited by 34

miR‐129‐5p inhibits proliferation, migration, and invasion in rectal adenocarcinoma cells through targeting E2F7

Wan, P., Bai, X., Yang, C., He, T., Luo, L., Wang, Y., Fan, M., Wang, Z., Lu, L., Yin, Y., et al. (2020) · Journal of Cellular Physiology · doi:10.1002/jcp.29501 · Cited by 29

Activating E2Fs mediate transcriptional regulation of human E2F6 repressor

Lyons, T. E., Salih, M., & Tuana, B. S. (2005) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00630.2004 · Cited by 28

A novel mitochondrial protein DIP mediates E2F1-induced apoptosis independently of p53

Stanelle, J., Tu-Rapp, H., & Pützer, B. M. (2004) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4401532 · Cited by 28

UV-C response of the ribonucleotide reductase large subunit involves both E2F-mediated gene transcriptional regulation and protein subcellular relocalization in tobacco cells

Lincker, F. (2004) · Nucleic Acids Research · doi:10.1093/nar/gkh310 · Cited by 27

E2F-6 Suppresses Growth-Associated Apoptosis of Human Hematopoietic Progenitor Cells by Counteracting Proapoptotic Activity of E2F-1

Kikuchi, J., Shimizu, R., Wada, T., Ando, H., Nakamura, M., Ozawa, K., & Furukawa, Y. (2007) · Stem Cells · doi:10.1634/stemcells.2007-0207 · Cited by 27

Wnt signaling regulates hepatocyte cell division by a transcriptional repressor cascade

Jin, Y., Anbarchian, T., Wu, P., Sarkar, A., Fish, M., Peng, W. C., & Nusse, R. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2203849119 · Cited by 26

Identification and Characterization of Novel Isoforms of Human DP-1

Ishida, H., Masuhiro, Y., Fukushima, A., Argueta, J. G. M., Yamaguchi, N., Shiota, S., & Hanazawa, S. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m500189200 · Cited by 26

The transcription factor E2F: a crucial switch in the control of homeostasis and tumorigenesis.

Fang, Z., & Han, Z. (2006) · PubMed · doi:10.14670/hh-21.403 · Cited by 26

E2F-1 regulation by an unusual DNA damage-responsive DP partner subunit

Ingram, L., Munro, S., Coutts, A. S., & Thangue, N. B. L. (2010) · Cell Death and Differentiation · doi:10.1038/cdd.2010.70 · Cited by 25

The Role of the E2F Transcription Factor Family in UV-Induced Apoptosis

Hazar-Rethinam, M. H., Endo‐Munoz, L., Gannon, O. M., & Saunders, N. A. (2011) · International Journal of Molecular Sciences · doi:10.3390/ijms12128947 · Cited by 26

DDT exposure induces cell cycle arrest and apoptosis of skin fibroblasts from Indo-Pacific humpback dolphin via mitochondria dysfunction

Yu, X., Yu, R.-Q., Zhang, X., Zhan, F., Sun, X. L., & Wu, Y. (2019) · Aquatic Toxicology · doi:10.1016/j.aquatox.2019.105229 · Cited by 25

Emerging role of E2F8 in human cancer

Lee, D. Y., Chun, J. N., Cho, M., So, I., & Jeon, J. (2023) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2023.166745 · Cited by 25

E2f1, E2f2, and E2f3 Control E2F Target Expression and Cellular Proliferation via a p53-Dependent Negative Feedback Loop

Timmers, C. D., Sharma, N., Opavský, R., Maiti, B., Wu, L., Wu, J., Orringer, D. A., Trikha, P., Saavedra, H. I., & Leone, G. W. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.02147-06 · Cited by 24

EAPP, a Novel E2F Binding Protein That Modulates E2F-dependent Transcription

Novy, M., Pohn, R., Andorfer, P., Novy-Weiland, T., Galos, B., Schwarzmayr, L., & Rotheneder, H. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e04-11-0975 · Cited by 25

The DP-1 Transcription Factor Is Required for Keratinocyte Growth and Epidermal Stratification

Chang, W. Y., Bryce, D. M., D’Souza, S. J. A., & Dagnino, L. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m408635200 · Cited by 24

Information-dependent enrichment analysis reveals time-dependent transcriptional regulation of the estrogen pathway of toxicity

Pendse, S. N., Maertens, A., Rosenberg, M. H., Roy, D., Fasani, R. A., Vantangoli, M. M., Madnick, S. J., Boekelheide, K., Fornace, A. J., Odwin, S.-A., et al. (2016) · Archives of Toxicology · doi:10.1007/s00204-016-1824-6 · Cited by 23

Unlocking the Power of Transcriptomic Biomarkers in Qualitative and Quantitative Genotoxicity Assessment of Chemicals

Thienpont, A., Cho, E., Williams, A., Meier, M. J., Yauk, C. L., Rogiers, V., Vanhaecke, T., & Mertens, B. (2024) · Chemical Research in Toxicology · doi:10.1021/acs.chemrestox.3c00318 · Cited by 22

E2F-7 couples DNA damage-dependent transcription with the DNA repair process

Zalmas, L., Coutts, A. S., Helleday, T., & Thangue, N. B. L. (2013) · Cell Cycle · doi:10.4161/cc.26078 · Cited by 22

Cell cycle oscillators underlying orderly proteolysis of E2F8

Wasserman, D., Nachum, S., Cohen, M., Enrico, T. P., Noach-Hirsh, M., Parasol, J., Zomer-Polak, S., Auerbach, N., Sheinberger-Chorni, E., Nevenzal, H., et al. (2020) · Molecular Biology of the Cell · doi:10.1091/mbc.e19-12-0725 · Cited by 25

Candidate nsSNPs that can affect the functions and interactions of cell cycle proteins

Savas, S., Ahmad, M., Shariff, M., Kim, D. Y., & Özçelik, H. (2004) · Proteins Structure Function and Bioinformatics · doi:10.1002/prot.20367 · Cited by 22

HIF proteins connect the RB-E2F factors to angiogenesis

Bakker, W. J., Weijts, B. G. M. W., Westendorp, B., & de Bruin, A. (2013) · Transcription · doi:10.4161/trns.23680 · Cited by 22

Posttranslational modifications of E2F family members in the physiological state and in cancer: Roles, mechanisms and therapeutic targets

Sun, M., Ji, Y., Zhang, G., Li, Y., Dong, F., & Wu, T. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.117147 · Cited by 23

Cell cycle-related genes associate with sensitivity to hydrogen peroxide-induced toxicity

Bekeschus, S., Liebelt, G., Menz, J., Singer, D., Wende, K., & Schmidt, A. (2022) · Redox Biology · doi:10.1016/j.redox.2022.102234 · Cited by 19

Highly and moderately aggressive mouse ovarian cancer cell lines exhibit differential gene expression

Du, F., Li, Y., Zhang, W., Kale, S. P., McFerrin, H. E., Davenport, I. R., Wang, G., Skripnikova, E., Li, X., Bowen, N. J., et al. (2016) · Tumor Biology · doi:10.1007/s13277-015-4518-4 · Cited by 19

CtBP2 proteome: Role of CtBP in E2F7-mediated repression and cell proliferation

Zhao, L., Subramanian, T., Vijayalingam, S., & Chinnadurai, G. (2014) · Genes & Cancer · doi:10.18632/genesandcancer.2 · Cited by 19

Association between B‑Myb proto‑oncogene and the development of malignant tumors (Review)

Jin, Y., Qi, G., Chen, G., Wang, C., & Fan, X. (2021) · Oncology Letters · doi:10.3892/ol.2021.12427 · Cited by 17

Characterisation and regulation of E2F-6 and E2F-6b in the rat heart: a potential target for myocardial regeneration?

Movassagh, M., Bicknell, K. A., & Brooks, G. (2005) · Journal of Pharmacy and Pharmacology · doi:10.1211/jpp.58.1.0009 · Cited by 17

Comprehensive Analysis of Prognostic and Immune Infiltrates for E2F Transcription Factors in Human Pancreatic Adenocarcinoma

Liu, X., Gao, Y., Liu, C., Chen, X., Zhou, L.-M., Yang, J.-W., Kui, X.-Y., & Pei, Z. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2020.606735 · Cited by 17

E2F-1 Regulates the Expression of a Subset of Target Genes during Skeletal Myoblast Hypertrophy

Hlaing, M., Spitz, P., Padmanabhan, K., Cabezas, B., Barker, C. S., & Bernstein, H. S. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m408391200 · Cited by 17

Gene expression analysis of human endometrial endothelial cells exposed to op′-DDT

Bredhult, C., Sahlin, L., & Olovsson, M. H. (2008) · Molecular Human Reproduction · doi:10.1093/molehr/gam091 · Cited by 16

A novel factor distinct from E2F mediates C-MYC promoter activation through its E2F element during exit from quiescence

Álvaro-Blanco, J., Martínez-Gac, L., Calonge, E., Rodríguez‐Martínez, M., Molina-Privado, I., Redondo, J. M., Alcamı́, J., Flemington, E. K., & Campanero, M. R. (2009) · Carcinogenesis · doi:10.1093/carcin/bgp002 · Cited by 16

Human E2F6 is alternatively spliced to generate multiple protein isoforms

Kherrouche, Z., de Launoit, Y., & Monté, D. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.03.099 · Cited by 16

Regulation of the Arf/p53 Tumor Surveillance Network by E2FPreprint

Iaquinta, P. J., Aslanian, A., & Lees, J. A. (2005) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2005.70.050 · Cited by 17

Characterization of sexual size dimorphism and sex-biased genes expression profile in the olive flounder

Ryu, J., Jung, J., Park, K., Lee, S., Park, I., Kim, W., & Kim, D. (2020) · Molecular Biology Reports · doi:10.1007/s11033-020-05843-3 · Cited by 15

H2AFZ: A Novel Prognostic Marker in Canine Melanoma and a Predictive Marker for Resistance to CDK4/6 Inhibitor Treatment

Bongiovanni, L., Andriessen, A., Silvestri, S., Porcellato, I., Brachelente, C., & de Bruin, A. (2021) · Frontiers in Veterinary Science · doi:10.3389/fvets.2021.705359 · Cited by 14

A Journey to the Core of the Plant Cell Cycle

Gutiérrez, C. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23158154 · Cited by 14

In vivo CRISPR/Cas9-mediated screen reveals a critical function of TFDP1 and E2F4 transcription factors in hematopoiesis

Tran, N. T., Graf, R., Acevedo‐Ochoa, E., Trombke, J., Weber, T., Sommermann, T. G., Salomon, C., Kühn, R., Rajewsky, K., & Chu, V. T. (2024) · Leukemia · doi:10.1038/s41375-024-02357-w · Cited by 16

Identification of Cellular Targets of MicroRNA-181a in HepG2 Cells: A New Approach for Functional Analysis of MicroRNAs

Tan, J. Y. L., Habib, N. A., Chuah, Y. W., Yau, Y. H., Shochat, S. G., & Chen, W. N. (2015) · PLoS ONE · doi:10.1371/journal.pone.0123167 · Cited by 13

Cyclin D1/cdk4 can interact with E2F4/DP1 and disrupts its DNA‐binding capacity

Scimè, A., Li, L., Ciavarra, G., & Whyte, P. (2007) · Journal of Cellular Physiology · doi:10.1002/jcp.21243 · Cited by 13

Identification of a Low-Frequency Missense Variant in E2F Transcription Factor 7 Associated with Colorectal Cancer Risk In A Chinese Population

Guo, A.-Y., Zhai, K., Xu, J., Hu, J. L., & Gao, L. (2017) · Europe PMC (PubMed Central) · doi:10.22034/apjcp.2017.18.1.271 · Cited by 12

Atypical E2Fs either Counteract or Cooperate with RB during Tumorigenesis Depending on Tissue Context

Moreno, E., Pandit, S. K., Toussaint, M. J. M., Bongiovanni, L., Harkema, L., van Essen, S. C., van Liere, E. A., Westendorp, B., & de Bruin, A. (2021) · Cancers · doi:10.3390/cancers13092033 · Cited by 14

Loss of E2F7 Expression Is an Early Event in Squamous Differentiation and Causes Derepression of the Key Differentiation Activator Sp1

Hazar-Rethinam, M. H., Cameron, S. R., Dahler, A. L., Endo‐Munoz, L., Smith, L., Rickwood, D., & Saunders, N. A. (2011) · Journal of Investigative Dermatology · doi:10.1038/jid.2010.430 · Cited by 12

E2F1 and E2F7 regulate gastric cancer cell proliferation, respectively, through transcriptional activation and transcriptional repression of MYBL2

Wu, T., Jiang, F., Wu, F., Zheng, G., Li, Y., & Wu, L.-Z. (2024) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2024.108027 · Cited by 12

Defining a transcriptional fingerprint of murine splenic B-cell development

Debnath, I., Roundy, K. M., Dunn, D. M., Weiss, R. B., Weis, J. J., & Weis, J. H. (2008) · Genes and Immunity · doi:10.1038/gene.2008.70 · Cited by 11

Interrogation of genome-wide, experimentally dissected gene regulatory networks reveals mechanisms underlying dynamic cellular state controlPreprint

Tan, X., Worley, J., Turunen, M. M., Wong, K., Fernández, E. C., Paull, E., Jones, S. J., Wang, J., Noh, H., Salvatori, B., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.06.28.449297 · Cited by 12

The roles of E2F7 in cancer: Current knowledge and future prospects

Chen, K.-Q., Lei, H.-B., Liu, X., & Wang, S.-Z. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e34362 · Cited by 12

Functional interplay between E2F7 and ribosomal rRNA gene transcription regulates protein synthesis

Coutts, A. S., Munro, S., & Thangue, N. B. L. (2018) · Cell Death and Disease · doi:10.1038/s41419-018-0529-6 · Cited by 10

E2F6: a member of the E2F family that does not modulate squamous differentiation

Wong, C. F., Barnes, L. M., Smith, L., Popa, C., Serewko-Auret, M. M., & Saunders, N. A. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.09.084 · Cited by 10

E2F6 is essential for cell viability in breast cancer cells during replication stress

Lafta, I. J. (2019) · TURKISH JOURNAL OF BIOLOGY · doi:10.3906/biy-1905-6 · Cited by 10

Transcriptional modulation in Mediterranean Mussel Mytilus galloprovincialis following exposure to four pharmaceuticals widely distributed in coastal areas

Bernardini, I., Mezzelani, M., Panni, M., Rovere, G. D., Nardi, A., Idrissi, O. E., Peruzza, L., Gorbi, S., Ferraresso, S., Bargelloni, L., et al. (2025) · Aquatic Toxicology · doi:10.1016/j.aquatox.2025.107255 · Cited by 10

An alternatively spliced form affecting the Marked Box domain of Drosophila E2F1 is required for proper cell cycle regulation

Kim, M., Tang, J. P., & Moon, N.-S. (2018) · PLoS Genetics · doi:10.1371/journal.pgen.1007204 · Cited by 7

E2F8 is a nonreceptor activator of heterotrimeric G proteins

Hagemann, I. S., Narzinski, K., & Baranski, T. (2007) · Journal of Molecular Signaling · doi:10.1186/1750-2187-2-3 · Cited by 7

Adding pieces to the puzzle of differentiated-to-anaplastic thyroid cancer evolution: the oncogene E2F7

Gugnoni, M., Lorenzini, E., do Valle, Í. F., Remondini, D., Castellani, G., Torricelli, F., Sauta, E., Donati, B., Ragazzi, M., Ghini, F., et al. (2023) · Cell Death and Disease · doi:10.1038/s41419-023-05603-8 · Cited by 9

Genomewide association study of HLA alloimmunization in previously pregnant blood donors

Seielstad, M. T., Page, G. P., Gaddis, N., Lanteri, M. C., Lee, T., Kakaiya, R., Barcellos, L. F., Criswell, L. A., Triulzi, D. J., Norris, P. J., et al. (2017) · Transfusion · doi:10.1111/trf.14402 · Cited by 7

Visualizing Dynamic E2F-Mediated Repression In Vivo

Agromayor, M., Wloga, E. H., Naglieri, B., Abrashkin, J., Verma, K., & Yamasaki, L. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.02101-05 · Cited by 7

The systems biology of neurofibromatosis type 1 — Critical roles for microRNA

Lee, M., Cho, J., Galas, D. J., & Wang, K. (2011) · Experimental Neurology · doi:10.1016/j.expneurol.2011.10.023 · Cited by 6

The presence of a feeder layer improves human corneal endothelial cell proliferation by altering the expression of the transcription factors Sp1 and NFI

Le‐Bel, G., Giasson, C., Deschambeault, A., Carrier, P., Germain, L., & Guérin, S. L. (2018) · Experimental Eye Research · doi:10.1016/j.exer.2018.07.009 · Cited by 6

Expression patterns and action analysis of genes associated with hepatitis virus infection during rat liver regeneration

Su, L.-J. (2006) · World Journal of Gastroenterology · doi:10.3748/wjg.v12.i47.7626 · Cited by 6

Identification and expression analysis of two zebrafish E2F5 genes during oogenesis and development

Yang, Q., Hu, J., Ding, Y., Zhao, C., Song, S., Gong, W., Tan, Z., & Song, P. (2009) · Molecular Biology Reports · doi:10.1007/s11033-009-9605-4 · Cited by 6

EFL-3/E2F7 modulates Wnt signalling by repressing the Nemo-like kinase LIT-1 during asymmetric epidermal cell division in Caenorhabditis elegans

Ferrando-Marco, M., & Barkoulas, M. (2025) · Development · doi:10.1242/dev.204546 · Cited by 2

RNA Sequencing Reveals Candidate Genes and Pathways Associated with Resistance to MDM2 Antagonist Idasanutlin in TP53 Wild-Type Chronic Lymphocytic Leukemia

Aptullahoğlu, E., Nakjang, S., Wallis, J. P., Marr, H. J., Marshall, S. R., Willmore, E., & Lunec, J. (2024) · Biomedicines · doi:10.3390/biomedicines12071388 · Cited by 5

E2F7 regulates transcription and maturation of multiple microRNAs to restrain cell proliferation

Vallejo-Rodríguez, J., Mitxelena, J., Apraiz, A., Malumbres, M., & Zubiaga, A. M. (2016) · European Journal of Cancer · doi:10.1016/s0959-8049(16)61601-5 · Cited by 5

CAGE-TSSchip: promoter-based expression profiling using the 5'-leading label of capped transcripts

Katayama, S., Kanamori-Katayama, M., Yamaguchi, K., Carninci, P., & Hayashizaki, Y. (2007) · Genome biology · doi:10.1186/gb-2007-8-3-r42 · Cited by 4

Radiobiologic Principles

Wilson, P. F., & Bedford, J. S. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4160-5897-7.00001-9 · Cited by 5

Non-Canonical Functions of the E2F/DP Pathway with Emphasis in Plants

Sánchez-Camargo, V. A., Romero-Rodr韌uez, S., & V醶quez-Ramos, J. M. (2021) · Phyton · doi:10.32604/phyton.2021.014967 · Cited by 5

E2F Transcription Factors in Cancer, More than the Cell Cycle

Broeker, C. D., & Andrechek, E. R. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-820472-6.00102-x · Cited by 5

CISD2 transcriptional activated by transcription factor E2F7 promotes the malignant progression of cervical cancer

Wang, L., Wang, Y., Wang, C., Kang, Y., & Ye, G. (2023) · Journal of Molecular Histology · doi:10.1007/s10735-023-10145-6 · Cited by 4

Correction: Atypical E2fs Control Lymphangiogenesis through Transcriptional Regulation of Ccbe1 and Flt4

Weijts, B. G. M. W., van Impel, A., Schulte‐Merker, S., & de Bruin, A. (2013) · PLoS ONE · doi:10.1371/annotation/25c7c486-9e68-4df9-af01-2fe1c5d1a2d4 · Cited by 4

Hepatocyte Cell Cycle Progression Depends on a Transcriptional Repressor Cascade Downstream of Wnt Signaling

Jin, Y., Anbarchian, T., Wu, P., Sarkar, A., Fish, M., & Nusse, R. (2021) · doi:10.1101/2021.10.15.464616 · Cited by 2

Comprehensive review regarding the association of E2Fs with the prognosis and immune infiltrates in human head and neck squamous cell carcinoma

Du, W., Xia, X., Gou, Q., Xie, Y., & Gao, L. (2024) · Asian Journal of Surgery · doi:10.1016/j.asjsur.2024.01.130 · Cited by 2

High expression of E2F transcription factors 7: An independent predictor of poor prognosis in patients with lung adenocarcinoma

Zhang, Y., Lyu, L., Wang, W., & Zhang, L. (2022) · Medicine · doi:10.1097/md.0000000000029253 · Cited by 2

Diverse Regulatory Functions of the E2F Family of Transcription Factors

Dick, F. A., & Dyson, N. J. (2007) · Springer eBooks · doi:10.1007/0-387-33915-9_6 · Cited by 2

Emerging Roles for the Retinoblastoma Gene Family

Vanderluit, J. L., Ferguson, K. L., & Slack, R. S. (2007) · Springer eBooks · doi:10.1007/0-387-33915-9_8 · Cited by 2

The regulatory network controlling DNA damage responses in Saccharomyces cerevisiae

Fu, Y. V. (2008) · University Library - University of Saskatchewan (University of Saskatchewan) · Cited by 2

Osteoclast Cytokinesis

Takegahara, N. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.11163-8 · Cited by 2

53BP1 regulates p53-E2F7-dependent transcriptional gene repression and participates in the Fanconi anemia pathway

Fu, Y.-D., Wu, W., Zhang, M., Rong, Z., Lin, B., Zhou, X., Li, D., Shi, X., Guo, J., Ma, S., et al. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.116152 · Cited by 1

Effects of some Endocrine Disruptors on Human and Grey Seal Uterine Cells

Bredhult, C. (2007) · Uppsala University Publications (Uppsala University) · Cited by 1

E2F1 induction following DNA damage and oncogene activation

Helgason, G. V. (2007) · Enlighten: Theses (The University of Glasgow)

Regulation of E2F1 Transcription Factor by Glycogen Synthase Kinase-3-Beta

Alvarez, G. G. (2005) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)

Adenovirus and its interaction with host cell proteins

Carr, S. (2007) · St Andrews Research Repository (St Andrews Research Repository)

Rb Inactivation Leads to E2F1-mediated DNA Double Strand Break Accumulation: A Dissertation

Pickering, M. (2006) · The Journal of the American Medical Association (JAMA) Network (American Medical Association) · doi:10.13028/h6jf-nf65

E2F1 AND TUMOR SUPPRESSION: THE ROLE OF p21, miRNAS, AND THE DNA DAMAGE RESPONSE

Weaks, R. L. (2010) · Digital Commons-TMC (Texas Medical Center)

Replication and the Cell Cycle

Richardson, H. E., Quinn, L. M., Amin, N., Herr, A., Brumby, A. M., Doyle, K. M., Humbert, P. O., & Secombe, J. (2006) · Wiley-VCH eBooks · doi:10.1002/3527600906.mcb.200500022

Function of the E2F Transcription Factor Family During Normal and Pathological Growth

Hauck, L., & von Harsdorf, R. (2004) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-18932-6_9

Purification and Characterization of Retinoblastoma like Factor-containing Protein Complexes from Drosophila melanogaster

Korenjak, M. (2006) · doi:10.5282/edoc.6324

E2F7, a novel E2F featuring DP‐independent repression of a subset of E2F‐regulated genes

Stefano, L. D., Jensen, M. R., & Helin, K. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg613 · Cited by 272

Cloning and Characterization of Mouse E2F8, a Novel Mammalian E2F Family Member Capable of Blocking Cellular Proliferation

Maiti, B., Li, J., de Bruin, A., Gordon, F., Timmers, C. D., Opavský, R., Patil, K., Tuttle, J., Cleghorn, W. M., & Leone, G. W. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m501410200 · Cited by 194

E2F-7: a distinctive E2F family member with an unusual organization of DNA-binding domains

Logan, N., Delavaine, L., Graham, A., Reilly, C., Wilson, J. R., Brummelkamp, T. R., Hijmans, E. M., Bernards, R., & Thangue, N. B. L. (2004) · Oncogene · doi:10.1038/sj.onc.1207649 · Cited by 111

The role of E2Fs in proliferation during development

Thurlings, I. (2010) · Utrecht University Repository (Utrecht University)

E2F7: a member of the E2F family with a novel mechanism of transcriptional repression

Kesoglidou, P.-X. (2012) · OpenGrey (Institut de l'Information Scientifique et Technique) · doi:10.5287/ora-2axjyvq9y