Specificity and Mechanism of Action of EHT 1864, a Novel Small Molecule Inhibitor of Rac Family Small GTPases
Shutes, Adam, Onesto, Cercina, Picard, Virginie, Leblond, Bertrand, Schweighoffer, Fabien, Der, Channing J.·2007·Journal of Biological Chemistry
Cited by (339)
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- Additional file 3 of Regulatory role of lncH19 in RAC1 alternative splicing: implication for RAC1B expression in colorectal cancerAurora Cordaro, Maria Magdalena Barreca, Chiara Zichittella, Marco Loria, Denise Anello, Goffredo Orazio Arena, Nicolina Sciaraffa, Claudia Coronnello, Giuseppe Pizzolanti, Riccardo Alessandro et al. · 2024 · Figshare
- Additional file 1 of Regulatory role of lncH19 in RAC1 alternative splicing: implication for RAC1B expression in colorectal cancerAurora Cordaro, Maria Magdalena Barreca, Chiara Zichittella, Marco Loria, Denise Anello, Goffredo Orazio Arena, Nicolina Sciaraffa, Claudia Coronnello, Giuseppe Pizzolanti, Riccardo Alessandro et al. · 2024 · Figshare
- Additional file 4 of Regulatory role of lncH19 in RAC1 alternative splicing: implication for RAC1B expression in colorectal cancerAurora Cordaro, Maria Magdalena Barreca, Chiara Zichittella, Marco Loria, Denise Anello, Goffredo Orazio Arena, Nicolina Sciaraffa, Claudia Coronnello, Giuseppe Pizzolanti, Riccardo Alessandro et al. · 2024 · Figshare
- Inhibitors of Mitogen-Activated Protein Kinase signaling transduction pathway are lethal to regenerating planariansEmily Scarrow, Percival Liu, Daniel Farber, Keevan Kearns, Eve Kolker, William Wallace · 2024 · Journal of High School Science
- Additional file 2 of Regulatory role of lncH19 in RAC1 alternative splicing: implication for RAC1B expression in colorectal cancerAurora Cordaro, Maria Magdalena Barreca, Chiara Zichittella, Marco Loria, Denise Anello, Goffredo Orazio Arena, Nicolina Sciaraffa, Claudia Coronnello, Giuseppe Pizzolanti, Riccardo Alessandro et al. · 2024 · Figshare
- Additional file 5 of Regulatory role of lncH19 in RAC1 alternative splicing: implication for RAC1B expression in colorectal cancerAurora Cordaro, Maria Magdalena Barreca, Chiara Zichittella, Marco Loria, Denise Anello, Goffredo Orazio Arena, Nicolina Sciaraffa, Claudia Coronnello, Giuseppe Pizzolanti, Riccardo Alessandro et al. · 2024 · Figshare
- Rac1 contributes to brain connectivity impairments and neuropsychiatric disorders in Tuberous Sclerosis ComplexTomasz Dulski, Olga Doszyń, Justyna Zmorzyńska · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Advancement in preclinical development of cancer treatment agents through modulation of Rac1: From EHop-016 to natural productsYingyi Liu, Sze-nga Wong, Aiping Lü, Joshua Ka-Shun Ko · 2025 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
- Disulfidptosis-based cancer therapy: Opportunity and challengeBo Wang, Zihui Liu, Junjie Li, Jiaxing Xu, Yamei Guo, J. Zhang, Ti Chu, Zhifen Feng, Qiying Jiang, Dongdong Wu · 2026 · Genes & Diseases
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- The gp120 Envelope Glycoprotein of HIV-1 Triggers Macropinocytosis in Primary CD4+ T Cells to Promote HIV-1 InfectionPraveen Manivannan, Cristina Santos da Costa, Yipei Tang, Xinghao Wang, Joel A. Swanson, Tomoyuki Murakami, Akira Ono, Philip D. King · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Research advances of disulfidptosis in inflammatory diseasesYizhao Ma, Xingpeng Yang, Yichen Bao, Lin Qi, Xiaohui Du, Pengyue Zhao · 2026 · Genes & Diseases
- Roles of Ras Homolog Guanosine Triphosphate Phosphohydrolases in Adipocyte Differentiation, Insulin Signaling, and Lipid Droplet DynamicsYuping Huang, Guoxun Chen, Yan Zhang · 2026 · Journal of Nutrition
- Perturbation of Rac1 signaling alters segmentation clock dynamics and somite sizeMaria Pappa, Charisios D. Tsiairis · 2026 · Development
- Functions of TIAM1 at the interface of centriole assembly and autolysosome cyclingPaula Almeida Coelho, Chenrong Yu, David Moore Glover · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- An Iridium(III) Complex Induces Immunogenic Methuosis and Reprograms Tumor-Associated Macrophages for Chemoimmunotherapy against KRAS-Mutated TumorsZhuoli Chen, Lina Xie, Tianying Wang, Jinzhe Liang, Yu Chen, Hui Chao · 2026 · Journal of Medicinal Chemistry
- GPC6 Lipid Shielding Sustains WNT5A Gradients to Prevent a RASopathy-like Developmental StateYeonjoo Kim, Yuguang Zhao, Aurora Xinshu Xu, Asif Nakhuda, Ana-Miruna Androniciuc, Gennadiy Tenin, Bernard D. Keavney, E. Yvonne Jones, Ian John McGough · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- BindingDB Entry 50019371: Advances in the development of Rho GTPase inhibitors.BindingDB · 2024 · UC San Diego
- BindingDB Entry 50030727: Structure-activity relationship of isoform selective inhibitors of Rac1/1b GTPase nucleotide binding.BindingDB · 2010 · UC San Diego
- Vav3 Potentiation of Androgen Receptor Activity in Prostate CancerShuyun Rao · 2010