The Endoplasmic Reticulum Enzyme DGAT2 Is Found in Mitochondria-associated Membranes and Has a Mitochondrial Targeting Signal That Promotes Its Association with Mitochondria

Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein

Shaner, N. C., Campbell, R. E., Steinbach, P. A., Giepmans, B. N. G., Palmer, A. E., & Tsien, R. Y. (2004) · Nature Biotechnology · doi:10.1038/nbt1037 · Cited by 4,619

A monomeric red fluorescent protein

Campbell, R. E., Tour, O., Palmer, A. E., Steinbach, P. A., Baird, G. S., Zacharias, D. A., & Tsien, R. Y. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.082243699 · Cited by 2,346

Biochemistry of Lipids, Lipoproteins and Membranes

(2021) · Elsevier eBooks · doi:10.1016/c2020-0-00089-7 · Cited by 1,402

Phospholipid synthesis in a membrane fraction associated with mitochondria.

Vance, J. E. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)39106-9 · Cited by 1,153

Identification of a gene encoding an acyl CoA:diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis

Cases, S., Smith, S. J., Zheng, Y.-W., Myers, H. M., Lear, S. R., Sande, E., Novak, S., Collins, C. C., Welch, C. L., Lusis, A. J., et al. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.22.13018 · Cited by 1,138

Thematic review series: Glycerolipids. DGAT enzymes and triacylglycerol biosynthesis

Yen, C.-L. E., Stone, S. J., Koliwad, S., Harris, C., & Farese, R. V. (2008) · Journal of Lipid Research · doi:10.1194/jlr.r800018-jlr200 · Cited by 1,105

Enzymes of triacylglycerol synthesis and their regulation

Coleman, R. (2003) · Progress in Lipid Research · doi:10.1016/s0163-7827(03)00051-1 · Cited by 985

The lipid handbook

Gunstone, F. D., Harwood, J. L., & Padley, F. B. (1994) · Cited by 972

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.

Mootha, V. K., Bunkenborg, J., Olsen, J. V., Hjerrild, M., Wisniewski, J. R., Stahl, E., Bolouri, M. S., Ray, H. N., Sihag, S., Kamal, M., et al. (2003) · Cell · doi:10.1016/s0092-8674(03)00926-7 · Cited by 889

Cloning of DGAT2, a Second Mammalian Diacylglycerol Acyltransferase, and Related Family Members

Cases, S., Stone, S. J., Zhou, P., Yen, E., Tow, B., Lardizabal, K. D., Voelker, T., & Farese, R. V. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m106219200 · Cited by 818

Stepwise Biogenesis of Subpopulations of Lipid Droplets in Nitrogen Starved Phaeodactylum tricornutum Cells

Jaussaud, A., Lupette, J., Salvaing, J., Jouhet, J., Bastien, O., Gromova, M., & Maréchal, É. (2020) · Frontiers in Plant Science · doi:10.3389/fpls.2020.00048 · Cited by 32

Apoptotic signals at the endoplasmic reticulum-mitochondria interface

Giamogante, F., Poggio, E., Barazzuol, L., Covallero, A., & Calí, T. (2021) · Advances in protein chemistry and structural biology · doi:10.1016/bs.apcsb.2021.02.007 · Cited by 30

Mechanisms of intestinal triacylglycerol synthesis

Stone, S. J. (2022) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2022.159151 · Cited by 32

Discovery of Ervogastat (PF-06865571): A Potent and Selective Inhibitor of Diacylglycerol Acyltransferase 2 for the Treatment of Non-alcoholic Steatohepatitis

Futatsugi, K., Cabral, S., Kung, D. W., Huard, K., Lee, E. C. Y., Boehm, M., Bauman, J. N., Clark, R. W., Coffey, S. B., Crowley, C., et al. (2022) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.2c01200 · Cited by 33

A novel role for DGATs in cancer

Hernandez‐Corbacho, M. J., & Obeid, L. M. (2018) · Advances in Biological Regulation · doi:10.1016/j.jbior.2018.12.001 · Cited by 28

Identification of a 13bp indel polymorphism in the 3′-UTR of DGAT2 gene associated with backfat thickness and lean percentage in pigs

Zang, L., Wang, Y., Sun, B., Zhang, X., Yang, C., Kang, L., Zhao, Z., & Jiang, Y. (2015) · Gene · doi:10.1016/j.gene.2015.09.047 · Cited by 29

Myocardial Fatty Acid Metabolism and Lipotoxicity in the Setting of Insulin Resistance

Kok, B. P., & Brindley, D. N. (2012) · Heart Failure Clinics · doi:10.1016/j.hfc.2012.06.008 · Cited by 29

Activation of diacylglycerol acyltransferase expressed in Saccharomyces cerevisiae: overexpression of Dga1p lacking the N-terminal region in the ∆snf2 disruptant produces a significant increase in its enzyme activity

Kamisaka, Y., Kimura, K., Uemura, H., & Shibakami, M. (2010) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-010-2725-x · Cited by 28

The role of alpha-synuclein in synucleinopathy: Impact on lipid regulation at mitochondria–ER membranes

Barbuti, P. A., Guardia‐Laguarta, C., Yun, T., Chatila, Z. K., Flowers, X. E., Wong, C., Santos, B. F. R., Larsen, S. B., Lotti, J. S., Hattori, N., et al. (2025) · npj Parkinson s Disease · doi:10.1038/s41531-025-00960-x · Cited by 31

Reduced Incorporation of Fatty Acids Into Triacylglycerol in Myotubes From Obese Individuals With Type 2 Diabetes

Sparks, L. M., Bosma, M., Brouwers, B., van de Weijer, T., Bilet, L., Schaart, G., Moonen‐Kornips, E., Eichmann, T. O., Lass, A., Hesselink, M. K. C., et al. (2014) · Diabetes · doi:10.2337/db13-1123 · Cited by 28

A Secreted Phospholipase A2 Induces Formation of Smooth Muscle Foam Cells Which Transdifferentiate to Macrophage-Like State

Giannotti, K. C., Weinert, S., Viana, M. N., Leiguez, E., Araujo, T. L. S., Laurindo, F. R. M., Lomonte, B., Braun-Dullaeus, R. C., & Teixeira, C. (2019) · Molecules · doi:10.3390/molecules24183244 · Cited by 27

The metabolic capacity of lipid droplet localized acyl-CoA synthetase 3 is not sufficient to support local triglyceride synthesis independent of the endoplasmic reticulum in A431 cells

Poppelreuther, M., Sander, S., Minden, F., Dietz, M. S., Exner, T., Du, C., Zhang, I. W., Ehehalt, F., Knüppel, L., Domschke, S., et al. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2018.03.003 · Cited by 27

Hepatic VLDL secretion: DGAT1 determines particle size but not particle number, which can be supported entirely by DGAT2

Irshad, Z., Chmel, N. P., Adya, R., & Zammit, V. A. (2018) · Journal of Lipid Research · doi:10.1194/jlr.m089300 · Cited by 26

DGAT2 partially compensates for lipid-induced ER stress in human DGAT1-deficient intestinal stem cells

van Rijn, J. M., van Hoesel, M., de Heus, C., van Vugt, A. H. M., Klumperman, J., Nieuwenhuis, E. E. S., Houwen, R. H. J., & Middendorp, S. (2019) · Journal of Lipid Research · doi:10.1194/jlr.m094201 · Cited by 26

Mitochondria-ER Tethering in Neurodegenerative Diseases

Raeisossadati, R., & Ferrari, M. (2020) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-020-01008-9 · Cited by 26

Circulating Mitochondrial DNA and Inter-Organelle Contact Sites in Aging and Associated Conditions

Picca, A., Guerra, F., Calvani, R., Romanò, R., Coelho‐Júnior, H. J., Damiano, F. P., Bucci, C., & Marzetti, E. (2022) · Cells · doi:10.3390/cells11040675 · Cited by 27

Basal re-esterification finetunes mitochondrial fatty acid utilization

Sharma, A. K., Wang, T., Othman, A., Khandelwal, R., Baláž, M., Modica, S., Zamboni, N., & Wolfrum, C. (2023) · Molecular Metabolism · doi:10.1016/j.molmet.2023.101701 · Cited by 26

From Non-Alcoholic Fatty Liver to Hepatocellular Carcinoma: A Story of (Mal)Adapted Mitochondria

Amorim, R., Magalhães, C. C., Borges, F., Oliveira, P. J., & Teixeira, J. (2023) · Biology · doi:10.3390/biology12040595 · Cited by 28

Increased hepatic mitochondrial FA oxidation reduces plasma and liver TG levels and is associated with regulation of UCPs and APOC-III in rats

Lindquist, C., Bjørndal, B., Rossmann, C. R., Tusubira, D., Svardal, A. M., Røsland, G. V., Tronstad, K. J., Hallström, S., & Berge, R. K. (2017) · Journal of Lipid Research · doi:10.1194/jlr.m074849 · Cited by 27

Beclin‐1 improves mitochondria‐associated membranes in the heart during endotoxemia

Sun, Y., Cai, Y., Qian, S., Chiou, H., & Zang, Q. S. (2020) · FASEB BioAdvances · doi:10.1096/fba.2020-00039 · Cited by 25

Cetacean epidermal specialization: A review

Menon, G. K., Elias, P. M., Wakefield, J. S., & Crumrine, D. A. (2022) · Anatomia Histologia Embryologia · doi:10.1111/ahe.12829 · Cited by 25

Expression of a type 2 diacylglycerol acyltransferase from Thalassiosira pseudonana in yeast leads to incorporation of docosahexaenoic acid β‐oxidation intermediates into triacylglycerol

Xu, J., Kazachkov, M., Jia, Y., Zheng, Z., & Zou, J. (2013) · FEBS Journal · doi:10.1111/febs.12537 · Cited by 25

Reorganization of cellular retinol-binding protein type 1 and lecithin:retinol acyltransferase during retinyl ester biosynthesis

Jiang, W., & Napoli, J. L. (2012) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2012.03.016 · Cited by 24

Emergence of Lipid Droplets in the Mechanisms of Carcinogenesis and Therapeutic Responses

Delmas, D., Cotte, A. K., Connat, J., Hermetet, F., Bouyer, F., & Aires, V. (2023) · Cancers · doi:10.3390/cancers15164100 · Cited by 24

Protein Localization at Mitochondria-ER Contact Sites in Basal and Stress Conditions

Ilacqua, N., Sánchez‐Álvarez, M., Bachmann, M., Costiniti, V., del Pozo, M. Á., & Giacomello, M. (2017) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2017.00107 · Cited by 23

Superresolution Imaging Identifies That Conventional Trafficking Pathways Are Not Essential for Endoplasmic Reticulum to Outer Mitochondrial Membrane Protein Transport

Salka, K., Bhuvanendran, S., Wilson, K., Bozidis, P., Mehta, M., Rainey, K. H., Sesaki, H., Patterson, G. H., Jaiswal, J. K., & Colberg‐Poley, A. M. (2017) · Scientific Reports · doi:10.1038/s41598-017-00039-5 · Cited by 23

Intestinal acyl-CoA:diacylglycerol acyltransferase 2 overexpression enhances postprandial triglyceridemic response and exacerbates high fat diet-induced hepatic triacylglycerol storage

Uchida, A., Slipchenko, M. N., Eustaquio, T., Leary, J. F., Cheng, J., & Buhman, K. K. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2013.04.013 · Cited by 24

p53 suppresses lipid droplet–fueled tumorigenesis through phosphatidylcholine

Xu, X., Wang, J., Xu, L. M., Li, P., & Jiang, P. (2024) · Journal of Clinical Investigation · doi:10.1172/jci171788 · Cited by 23

The buzz in the field: the interaction between viruses, mosquitoes, and metabolism

Ratnayake, O. C., Chotiwan, N., Saavedra-Rodríguez, K., & Perera, R. M. (2023) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2023.1128577 · Cited by 25

Post-translational modifications and protein quality control of mitochondrial channels and transporters

Kadam, A. A., Jadiya, P., & Tomar, D. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1196466 · Cited by 23

Mechanisms of Lipid Droplet Accumulation in Steatotic Liver Diseases

Dempsey, J. L., Ioannou, G. N., & Carr, R. M. (2023) · Seminars in Liver Disease · doi:10.1055/a-2186-3557 · Cited by 24

The regulatory role of adipocyte mitochondrial homeostasis in metabolism-related diseases

Song, H., Zhang, X., Wang, J., Wu, Y., Xiong, T., Shen, J., Lin, R., Xiao, T., & Lin, W. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1261204 · Cited by 22

Biochemical characterization of human acyl coenzyme A: 2-monoacylglycerol acyltransferase-3 (MGAT3)

Brandt, C., McFie, P. J., & Stone, S. J. (2016) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2016.05.071 · Cited by 23

The endoplasmic reticulum and casein-containing vesicles contribute to milk fat globule membrane

Honvo‐Houeto, E., Henry, C., Chat, S., Layani-Moreno, S., & Truchet, S. (2016) · Molecular Biology of the Cell · doi:10.1091/mbc.e16-06-0364 · Cited by 23

Deficiency in perilipin 5 reduces mitochondrial function and membrane depolarization in mouse hearts

Andersson, L. K., Drevinge, C., Mardani, I., Dalen, K. T., Ståhlman, M., Klevstig, M., Lundqvist, A., Haugen, F., Adiels, M., Fogelstrand, P., et al. (2017) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2017.07.021 · Cited by 23

Membrane topology and identification of key residues of EaDAcT, a plant MBOAT with unusual substrate specificity

Tran, T. N. T., Shelton, J. M., Brown, S. J., & Durrett, T. P. (2017) · The Plant Journal · doi:10.1111/tpj.13636 · Cited by 22

Overexpression of DGAT2 Stimulates Lipid Droplet Formation and Triacylglycerol Accumulation in Bovine Satellite Cells

Zhang, J., Choi, S. H., Li, Q., Wang, Y., Sun, B., Tang, L., Wang, E.-Z., Hua, H., & Li, X. (2022) · Animals · doi:10.3390/ani12141847 · Cited by 22

Characteristics of Transcriptome and Metabolome Concerning Intramuscular Fat Content in Beijing Black Pigs

Hou, X., Zhang, R., Yang, M. G., Niu, N., Zong, W., Yang, L., Li, H., Hou, R., Wang, X., Wang, L., et al. (2023) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.3c02669 · Cited by 22

Vitamin D produces a perilipin 2-dependent increase in mitochondrial function in C2C12 myotubes

Schnell, D. M., Walton, R. G., Vekaria, H. J., Sullivan, P. G., Bollinger, L. M., Peterson, C. A., & Thomas, D. T. (2018) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2018.11.002 · Cited by 22

An AI-guided screen identifies probucol as an enhancer of mitophagy through modulation of lipid droplets

Moskal, N., Visanji, N. P., Gorbenko, O., Narasimhan, V., Tyrrell, H., Nash, J., Lewis, P. N., & McQuibban, G. A. (2023) · PLoS Biology · doi:10.1371/journal.pbio.3001977 · Cited by 21

Single-cell transcriptional profiling of hearts during cardiac hypertrophy reveals the role of MAMs in cardiomyocyte subtype switching

Luan, Y., Guo, G., Luan, Y., Yang, Y., & Yuan, R. (2023) · Scientific Reports · doi:10.1038/s41598-023-35464-2 · Cited by 21

Monoacylglycerol O-acyltransferase 1 (MGAT1) localizes to the ER and lipid droplets promoting triacylglycerol synthesis

Lee, Y. J., & Kim, J. W. (2017) · BMB Reports · doi:10.5483/bmbrep.2017.50.7.036 · Cited by 21

Dialogue between mitochondria and endoplasmic reticulum-potential therapeutic targets for age-related cardiovascular diseases

Chen, C., Dong, X., Zhang, W., Chang, X., & Gao, W. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1389202 · Cited by 22

Molecular mechanisms of lipid droplets-mitochondria coupling in obesity and metabolic syndrome: insights and pharmacological implications

Zhang, C., Zheng, M., Bai, R., Chen, J., Yang, H., & Luo, G. (2024) · Frontiers in Physiology · doi:10.3389/fphys.2024.1491815 · Cited by 23

Exercise regulation of hepatic lipid droplet metabolism

la Fuente, F. P.-D., Bórquez, J. C., Díaz‐Castro, F., Espinosa, A., Chiong, M., & Troncoso, R. (2022) · Life Sciences · doi:10.1016/j.lfs.2022.120522 · Cited by 20

Rab1b facilitates lipid droplet growth by ER–to–lipid droplet targeting of DGAT2

Malis, Y., Armoza-Eilat, S., Nevo-Yassaf, I., Dukhovny, A., Sklan, E. H., & Hirschberg, K. (2024) · Science Advances · doi:10.1126/sciadv.ade7753 · Cited by 21

Characterization of the interaction of diacylglycerol acyltransferase-2 with the endoplasmic reticulum and lipid droplets

McFie, P. J., Jin, Y., Banman, S. L., Beauchamp, E., Berthiaume, L. G., & Stone, S. J. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2014.06.004 · Cited by 20

Treatment of human skeletal muscle cells with inhibitors of diacylglycerol acyltransferases 1 and 2 to explore isozyme-specific roles on lipid metabolism

Løvsletten, N. G., Vu, H., Skagen, C., Lund, J., Kase, E. T., Thoresen, G. H., Zammit, V. A., & Rustan, A. C. (2020) · Scientific Reports · doi:10.1038/s41598-019-57157-5 · Cited by 21

Critical hubs of renal ischemia-reperfusion injury: endoplasmic reticulum-mitochondria tethering complexes

Zhao, H., Han, Q., Ding, X., Yan, J.-Y., Li, Q., Zhang, D., & Zhu, H. (2020) · Chinese Medical Journal · doi:10.1097/cm9.0000000000001091 · Cited by 20

The Mitochondrial-associated ER membrane (MAM) compartment and its dysregulation in Amyotrophic Lateral Sclerosis (ALS)

Parakh, S., & Atkin, J. D. (2021) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2021.02.002 · Cited by 20

Mitochondria–membranous organelle contacts at a glance

Diokmetzidou, A., & Scorrano, L. (2025) · Journal of Cell Science · doi:10.1242/jcs.263895 · Cited by 23

Unraveling the complex interplay between Mitochondria-Associated Membranes (MAMs) and cardiovascular Inflammation: Molecular mechanisms and therapeutic implications

Chen, X., Yang, Y., Zhou, Z., Yu, H., Zhang, S., Huang, S., Wei, Z., Ren, K., & Jin, Y. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.112930 · Cited by 21

Inhibiting diacylglycerol acyltransferase-1 reduces lipid biosynthesis in bovine blastocysts produced in vitro

Cañón-Beltrán, K., Giraldo, J. J. G., Cajas, Y. N., Beltrán-Breña, P., Hidalgo, C. O., Vásquez, N., Leal, C. L. V., Gutiérrez‐Adán, A., González, E. M., & Rizos, D. V. (2020) · Theriogenology · doi:10.1016/j.theriogenology.2020.09.014 · Cited by 19

DGAT1 protects against lipid induced-hepatic lipotoxicity in grass carp (Ctenopharyngodon idellus)

Sun, J. H., Wu, W., Xu, X., & Ji, H. (2020) · Aquaculture · doi:10.1016/j.aquaculture.2020.736328 · Cited by 19

Identification of small subunit of serine palmitoyltransferase a as a lysophosphatidylinositol acyltransferase 1‐interacting protein

Hirata, Y., Yamamori, N., Kono, N., Lee, H., Inoué, T., & Arai, H. (2013) · Genes to Cells · doi:10.1111/gtc.12046 · Cited by 19

DGAT2 stability is increased in response to DGAT1 inhibition in gene edited HepG2 cells

McFie, P. J., Chumala, P., Katselis, G. S., & Stone, S. J. (2021) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2021.158991 · Cited by 18

Dictyostelium discoideum Dgat2 Can Substitute for the Essential Function of Dgat1 in Triglyceride Production but Not in Ether Lipid Synthesis

Du, X., Herrfurth, C., Gottlieb, T., Kawelke, S., Feussner, K., Rühling, H., Feußner, I., & Maniak, M. (2014) · Eukaryotic Cell · doi:10.1128/ec.00327-13 · Cited by 18

The expression and regulation of enzymes mediating the biosynthesis of triglycerides and phospholipids in keratinocytes/epidermis

Jiang, Y. J., & Feingold, K. R. (2011) · Dermato-Endocrinology · doi:10.4161/derm.3.2.14995 · Cited by 18

Imaging Lipid Droplet Fusion and Growth

Sun, Z., Gong, J., Wu, L., & Li, P. (2013) · Methods in cell biology · doi:10.1016/b978-0-12-408051-5.00013-9 · Cited by 18

Isolation of Mitochondria-Associated Membranes (MAM) from Mouse Brain Tissue

Schreiner, B., & Ankarcrona, M. (2017) · Methods in molecular biology · doi:10.1007/978-1-4939-6824-4_5 · Cited by 18

Tapping lipid droplets: A rich fat diet of intracellular bacterial pathogens

Hüsler, D., Stauffer, P., & Hilbi, H. (2023) · Molecular Microbiology · doi:10.1111/mmi.15120 · Cited by 17

(−)-Epicatechin-3-O-β-d-allopyranoside from Davallia formosana, Prevents Diabetes and Hyperlipidemia by Regulation of Glucose Transporter 4 and AMP-Activated Protein Kinase Phosphorylation in High-Fat-Fed Mice

Shih, C., Wu, J., Jian, J.-Y., Lin, C., & Ho, H. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms161024983 · Cited by 17

Hepatic synthesis of triacylglycerols containing medium-chain fatty acids is dominated by diacylglycerol acyltransferase 1 and efficiently inhibited by etomoxir

Wunderling, K., Leopold, C., Jamitzky, I., Yaghmour, M. H., Zink, F., Kratky, D., & Thiele, C. (2020) · Molecular Metabolism · doi:10.1016/j.molmet.2020.101150 · Cited by 17

Fat in the heart: The enzymatic machinery regulating cardiac triacylglycerol metabolism

Heier, C., & Haemmerle, G. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2016.02.014 · Cited by 18

ARAP2 promotes GLUT1-mediated basal glucose uptake through regulation of sphingolipid metabolism

Chaudhari, A., Håversen, L., Mobini, R., Andersson, L. K., Ståhlman, M., Lu, E., Rutberg, M., Fogelstrand, P., Ekroos, K., Mardinoğlu, A., et al. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2016.07.009 · Cited by 17

Inactivation of human DGAT2 by oxidative stress on cysteine residues

Jung, S., Choi, M., Choi, K., Kwon, E. B., Kang, M.-G., Kim, D., Jeong, H., Kim, J., Kim, J. H., Kim, M. O., et al. (2017) · PLoS ONE · doi:10.1371/journal.pone.0181076 · Cited by 17

Bioenergetics and lipid metabolism in Alzheimer's disease: From cell biology to systemic health

Maioli, S., Nalvarte, I., Ankarcrona, M., Schultzberg, M., Zuloaga, K. L., Goikolea, J., Visser, P. J., Strooper, B. D., Winblad, B., Pizzo, P., et al. (2025) · Journal of Internal Medicine · doi:10.1111/joim.70036 · Cited by 19

Mitochondria isolated from lipid droplets of white adipose tissue reveal functional differences based on lipid droplet size

Brownstein, A. J., Veliova, M., Acín‐Pérez, R., Villalobos, F., Petcherski, A., Tombolato, A., Liesa, M., & Shirihai, O. S. (2023) · Life Science Alliance · doi:10.26508/lsa.202301934 · Cited by 16

Molecular identification of transmembrane protein 68 as an endoplasmic reticulum-anchored and brain-specific protein

Chang, P., Heier, C., Qin, W.-Z., Han, L., Huang, F., & Sun, Q. X. (2017) · PLoS ONE · doi:10.1371/journal.pone.0176980 · Cited by 16

A fatty acid analogue targeting mitochondria exerts a plasma triacylglycerol lowering effect in rats with impaired carnitine biosynthesis

Lindquist, C., Bjørndal, B., Rossmann, C. R., Svardal, A. M., Hallström, S., & Berge, R. K. (2018) · PLoS ONE · doi:10.1371/journal.pone.0194978 · Cited by 16

Rotavirus-mediated DGAT1 degradation: A pathophysiological mechanism of viral-induced malabsorptive diarrhea

Liu, Z., Smith, H. R., Criglar, J. M., Valentin, A. J., Karandikar, U. C., Zeng, X., Estes, M. K., & Crawford, S. E. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2302161120 · Cited by 15

Inhibition of sterol O-acyltransferase 1 blocks Zika virus infection in cell lines and cerebral organoids

Schöbel, A., dos Reis, V. P., Burkhard, R., Hehner, J., Schneider, L., Schauflinger, M., Vièyres, G., & Herker, E. (2024) · Communications Biology · doi:10.1038/s42003-024-06776-4 · Cited by 15

The Interplay of Microtubules with Mitochondria–ER Contact Sites (MERCs) in Glioblastoma

Grespi, F., Vianello, C., Cagnin, S., Giacomello, M., & Mario, A. D. (2022) · Biomolecules · doi:10.3390/biom12040567 · Cited by 15

Two Predicted Transmembrane Domains Exclude Very Long Chain Fatty acyl-CoAs from the Active Site of Mouse Wax Synthase

Kawelke, S., & Feußner, I. (2015) · PLoS ONE · doi:10.1371/journal.pone.0145797 · Cited by 15

Preferential lipolysis of DGAT1 over DGAT2 generated triacylglycerol in Huh7 hepatocytes

Selvaraj, R., Zehnder, S. V., Watts, R., Lian, J., Das, C., Nelson, R., & Lehner, R. S. (2023) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2023.159376 · Cited by 14

Interplay of mitochondria-associated membrane proteins and autophagy: Implications in neurodegeneration

Kulkarni, P. G., Mohire, V. M., Waghmare, P. P., & Banerjee, T. (2024) · Mitochondrion · doi:10.1016/j.mito.2024.101874 · Cited by 16

Regulation of lipid metabolism in pancreatic beta cells by interferon gamma: A link to anti-viral function

Truong, N., Lydic, T. A., Bazil, J. N., Suryadevara, A., & Olson, L. K. (2020) · Cytokine · doi:10.1016/j.cyto.2020.155147 · Cited by 14

Colorimetric in situ assay of membrane-bound enzyme based on lipid bilayer inhibition of ion transport

Zhang, J., Li, D., Yue, X., Zhang, M., Liu, P., & Li, G. (2018) · Theranostics · doi:10.7150/thno.25123 · Cited by 13

Diacylglycerol acyltransferase-2 and monoacylglycerol acyltransferase-2 are ubiquitinated proteins that are degraded by the 26S proteasome

Brandt, C., McFie, P. J., & Stone, S. J. (2016) · Biochemical Journal · doi:10.1042/bcj20160418 · Cited by 13

Lipid droplet dynamics in type 2 diabetes and its complications: pathophysiological insights and therapeutic options

Long, C., Li, Z., Jiang, L., Yang, X., Deng, S., Jiang, Y., Zhang, B., & Yue, R. (2025) · Lipids in Health and Disease · doi:10.1186/s12944-025-02747-8 · Cited by 14

The evolving landscape of ER-LD contact sites

Kumar, A., Yadav, S., & Choudhary, V. (2024) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2024.1483902 · Cited by 15

Post-Translational Modification of Cysteines: A Key Determinant of Endoplasmic Reticulum-Mitochondria Contacts (MERCs)

Bassot, A., Chen, J., & Simmen, T. (2021) · Contact · doi:10.1177/25152564211001213 · Cited by 12

Activation of ER stress signalling increases mortality after a major trauma

Abdullahi, A., Barayan, D., Vinaik, R., Diao, L., Yu, N., & Jeschke, M. G. (2020) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.15548 · Cited by 12

Enterocyte Fatty Acid Handling Proteins and Chylomicron Formation

Cifarelli, V., & Abumrad, N. A. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-809954-4.00048-7 · Cited by 16

Biocatalysis and biomolecular engineering

Shaw, J.-F., & HOU, C. T. (2010) · Wiley eBooks · Cited by 12

Editorial: Lipid droplets and mitochondria in metabolic diseases

Su, W., Chi, Y., & An, Y. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1266356 · Cited by 12

Environmental Pollutant‐Induced Disruption of Lipid Droplet Homeostasis in Aquatic Animals: Molecular Mechanisms and Cross‐Scale Health Effects

Huang, X., Xie, D., & Wang, J. (2025) · Reviews in Aquaculture · doi:10.1111/raq.70086 · Cited by 12

Lipid Metabolism in Diatoms

Tanaka, T., Yoneda, K., & Maeda, Y. (2022) · Springer eBooks · doi:10.1007/978-3-030-92499-7_18 · Cited by 11

A-Syn(ful) MAM: A Fresh Perspective on a Converging Domain in Parkinson’s Disease

Barbuti, P. A. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25126525 · Cited by 12

Superresolution imaging of viral protein trafficking

Colberg‐Poley, A. M., Patterson, G. H., Salka, K., Bhuvanendran, S., Yang, D. X., & Jaiswal, J. K. (2015) · Medical Microbiology and Immunology · doi:10.1007/s00430-015-0395-0 · Cited by 12

Endogenous levels of 1-O-acylceramides increase upon acidic ceramidase deficiency and decrease due to loss of Dgat1 in a tissue-dependent manner

Bayerle, A., Marsching, C., Rabionet, M., Dworski, S., Kamani, M. A., Chitraju, C., Gluchowski, N. L., Gabriel, K. R., Herzer, S., Jennemann, R., et al. (2020) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2020.158741 · Cited by 11

Role of Dgat2 in Glucose Uptake and Fatty Acid Metabolism in C2C12 Skeletal Myotubes

Bu, S. (2023) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.2307.07018 · Cited by 10

Diacylglycerol O-acyltransferase isoforms play a role in peridroplet mitochondrial fatty acid metabolism in bovine liver

Wang, S., Zhang, B., Mauck, J., Loor, J. J., Fan, W., Tian, Y., Yang, T., Chang, Y., Xie, M., Aernouts, B., et al. (2024) · Journal of Dairy Science · doi:10.3168/jds.2024-24738 · Cited by 12

The triglyceride-synthesizing enzyme diacylglycerol acyltransferase 2 modulates the formation of the hepatitis C virus replication organelle

Reichert, I., Lee, J., Weber, L., Fuh, M. M., Schlaeger, L., Rößler, S., Kinast, V., Schlienkamp, S., Conradi, J., Vondran, F. W. R., et al. (2024) · PLoS Pathogens · doi:10.1371/journal.ppat.1012509 · Cited by 10

Copper-Induced DRP1 Activation Disrupts Mitochondrial-Lipid Droplet Contact to Promote Hepatic Steatosis

Li, Q., Su, L., Guo, P., Liao, J., & Tang, Z. (2025) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.5c02147 · Cited by 10

Identification of calnexin as a diacylglycerol acyltransferase-2 interacting protein

Brandt, C., McFie, P. J., Vu, H., Chumala, P., Katselis, G. S., & Stone, S. J. (2019) · PLoS ONE · doi:10.1371/journal.pone.0210396 · Cited by 10

A NOVEL ASSAY OF ACYL‐COA:DIACYLGLYCEROL ACYLTRANSFERASE ACTIVITY UTILIZING FLUORESCENT SUBSTRATE1

Sanderson, M. C., & Venable, M. E. (2012) · Journal of Phycology · doi:10.1111/j.1529-8817.2012.01137.x · Cited by 10

Sphingolipids: Less Enigmatic but Still Many Questions about the Role(s) of Ceramide in the Synthesis/Function of the Ganglioside Class of Glycosphingolipids

Schengrund, C. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25126312 · Cited by 9

Perilipins: key targets for regulating lipid metabolism and alleviating abnormal lipid metabolism through exercise

Niu, Y.-J., Liu, J., Zhang, J., Lu, S., Wang, K., Zhu, Z., & Cao, Z. (2025) · Diabetology & Metabolic Syndrome · doi:10.1186/s13098-025-01965-5 · Cited by 9

Nafion by-product 2 disturbs lipid homeostasis in zebrafish embryo

Gui, W., Guo, H., Wang, J., Wang, C., Guo, Y., Zhang, K., Dai, J., & Zhao, Y. (2023) · Environmental Pollution · doi:10.1016/j.envpol.2023.121178 · Cited by 9

Murine Diacylglycerol Acyltransferase-2 (DGAT2) Can Catalyze Triacylglycerol Synthesis and Promote Lipid Droplet Formation Independent of Its Localization to the Endoplasmic Reticulum

McFie, P. J., Banman, S. L., Kary, S., & Stone, S. J. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.256008 · Cited by 149

J. Biol. Chem.

Stone, S., Levin, M., Zhou, P., Han, J., Walther, T. C., & Farese, R. (2008) · MPG.PuRe (Max Planck Society)

Characterization of the interaction of diacylglycerol acyltransferase-2 with the endoplasmic reticulum and lipid droplets

McFie, P. J., Jin, Y., Banman, S. L., Beauchamp, E., Berthiaume, L. G., & Stone, S. J. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2014.06.004 · Cited by 20

Diacylglycerol acyltransferase-2 contains a c-terminal sequence that interacts with lipid droplets

McFie, P. J., Banman, S. L., & Stone, S. J. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2018.06.008 · Cited by 39

Diacylglycerol Acyltransferase-2 (DGAT2) and Monoacylglycerol Acyltransferase-2 (MGAT2) Interact to Promote Triacylglycerol Synthesis

Jin, Y., McFie, P. J., Banman, S. L., Brandt, C., & Stone, S. J. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.571190 · Cited by 87