The DOI matches its Crossref record; 54 of the 54 references it cites were found in a registry or an index.
Neuroinflammation pathways: a general review
Abstract
Activated microglial cells play an important role in immune and inflammatory responses in central nervous system and neurodegenerative diseases. Many pro-apoptotic pathways are mediated by signaling molecules that are produced during neuroinflammation. In glial cells, NF-κB, a transcription factor, initiates and regulates the expression of several inflammatory processes during inflammation which are attributed to the pathology of the several neurodegenerative diseases. In this review, we discuss the most important neuroinflammatory mediators with their pathways. Attenuating cytokines production and controlling microglial inflammatory response, which are the result of understanding neuroinflammation pathways, are considered therapeutic strategies for treating neurodegenerative diseases with an inflammatory component.
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Cites
1 retracted
Han, L., Li, C., Sun, B., Xie, Y., Guan, Y., Ma, Z.-J., & Chen, L. (2016) · Journal of Diabetes Research · doi:10.1155/2016/2641248 · Cited by 77
RetractedShared Principles in NF-κB Signaling
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Mechanisms underlying inflammation in neurodegeneration
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LPS induction of gene expression in human monocytes
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Ubiquitin signalling in the NF-κB pathway
Chen, Z. J. (2005) · Nature Cell Biology · doi:10.1038/ncb0805-758 · Cited by 1,184
Role of neuroinflammation in neurodegenerative diseases (Review)
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CNS immune privilege: hiding in plain sight
Carson, M. J., Doose, J. M., Melchior, B., Schmid, C. D., & Ploix, C. C. (2006) · Immunological Reviews · doi:10.1111/j.1600-065x.2006.00441.x · Cited by 795
Mitochondrial reactive oxygen species drive proinflammatory cytokine production
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Cited by
Dhapola, R., Hota, S. S., Sarma, P., Bhattacharyya, A., Medhi, B., & Reddy, D. H. (2021) · Inflammopharmacology · doi:10.1007/s10787-021-00889-6 · Cited by 383
Microglia: Agents of the CNS Pro-Inflammatory Response
Rodríguez-Gómez, J. A., Kavanagh, E., Engskog-Vlachos, P., Engskog, M. K. R., Herrera, A. J., Espinosa-Oliva, A. M., Joseph, B., Hajji, N., Venero, J. L., & Burguillos, M. A. (2020) · Cells · doi:10.3390/cells9071717 · Cited by 365
Kopp, K. O., Glotfelty, E. J., Li, Y., & Greig, N. H. (2022) · Pharmacological Research · doi:10.1016/j.phrs.2022.106550 · Cited by 298
Fernández-Calle, R., Konings, S. C., Frontiñán-Rubio, J., García-Revilla, J., Camprubí-Ferrer, L., Svensson, M., Martinson, I., Boza-Serrano, A., Venero, J. L., Nielsen, H. M., et al. (2022) · Molecular Neurodegeneration · doi:10.1186/s13024-022-00566-4 · Cited by 278
Microglia and Neuroinflammation: What Place for P2RY12?
Gómez Morillas, A., Besson, V. C., & Lerouet, D. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22041636 · Cited by 214
Metadata
- Authors
- Shabab, T., Khanabdali, R., Moghadamtousi, S. Z., Kadir, H. A., & Mohan, G.
- Venue
- International Journal of Neuroscience
- Publisher
- Informa UK Limited
- Published
- 2016-08-09
- Volume
- 127
- Issue
- 7
- Pages
- 624-633
- ISSN
- 0020-7454 (ISSN-L)
- 1543-5245
- OpenAlex
- W2462334125
- Cited by
- 632
- References
- 54
- FWCI
- 9.50
- Type
- journal article
- Language
- en
- Open access
- closed
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- Shabab, T., Khanabdali, R., Moghadamtousi, S. Z., Kadir, H. A., & Mohan, G. (2017). Neuroinflammation pathways: a general review. International Journal of Neuroscience. https://doi.org/10.1080/00207454.2016.1212854
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
