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Cited by 183Hormonal and reproductive studiesAdipokines, Inflammation, and Metabolic DiseasesDiabetes, Cardiovascular Risks, and Lipoproteins

The DOI matches its Crossref record; 37 of the 38 references it cites were found in a registry or an index.

RELATIONSHIP BETWEEN BMI, TOTAL TESTOSTERONE, SEX HORMONE-BINDING-GLOBULIN, LEPTIN, INSULIN AND INSULIN RESISTANCE IN OBESE MEN

Osuna C., J. A., Gómez-Pérez, R., Arata-Bellabarba, G., Villaroel, V.·2006·Archives of Andrology
DOI 10.1080/01485010600692017
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Abstract

The objective of this work was to evaluate the relationship between sex steroid hormones, sex hormone-binding-globulin, leptin, insulin and insulin resistance in obese men. Anthropometrical indexes, total testosterone (Tt), free testosterone (fT), estradiol (E), sex hormone-binding-globulin (SHBG), glucemia, insulin and leptin were measured in 77 men, with ages between 20 and 60 years. According to their body mass index (BMI), subjects were grouped into three categories: normal body weight ( 30 kg/m2). Insulin resistance index was obtained by the homeostasis assessment model for insulin resistance (HOMA-IR). Total testosterone and SHBG concentrations were lower in the obese group compared with normal and overweight subjects (p < 0.05). The mean insulin concentration was significantly higher in the obese group compared with the other groups (p < 0.05). T was negatively correlated with the BMI (r = -0.447; p < .01), WC (r = -0.464); p < .01, leptin (r = -0.382; p < .01), insulin (r = -0.391; p < 0.01) and also with the HOMA-IR (r = -0.416; p < 0.01). The SHBG negatively and significantly correlated with BMI (r = -0.334; p < 0.01) and WC index (= -0.322; p < 0.01), as well with insulin levels (r = -0.313; p < 0.01) and insulin resistance (= -0.266; p < 0.05). Our results shows that in a sample of men, Tt and SHBG concentrations proportionally diminished with both the increase of BMI and insulin resistance index.

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Crossref · 10.1080/01485010600692017

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Show all 38 references

Research works printed but not linked: 10

  1. Björntorp P, 1997, Diabetes Rev, 5, 52
  2. Frühbeck G, 2001, Am J Physiol Soc, E-827
  3. Haffner SM, 1993, Int J Obes Relat Metab Disord, 17, 643
  4. Isidori AM, 1999, J Clin Endocrinol Metab, 84, 3673
  5. Marin P, 1992, Int J Obes Relat Metab Disord, 16, 991
  6. Meigs JB, 1997, The Framingham Offspring Study. Diabetes, 46, 1594
  7. Pasquali R, 1995, J Clin Endocrinol Metab, 80, 654
  8. Rosenbaum M, 1998, TEM, 9, 117
  9. Saad MF, 1997, J Clin Endocrinol Metab, 82, 579
  10. Strain G, 1994, J Clin Endocrinol Metab, 79, 1173

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Metadata

Authors
Osuna C., J. A., Gómez-Pérez, R., Arata-Bellabarba, G., & Villaroel, V.
Affiliations
Universidad de Los Andes (VE)
Venue
Archives of Andrology
Publisher
Informa UK Limited
Published
2006-01
Volume
52
Issue
5
Pages
355-361
ISSN
0148-5016 (ISSN-L)
DOI
10.1080/01485010600692017
OpenAlex
W2162557413
Cited by
183
References
38
Citations by year
2026: 2 · 2025: 4 · 2024: 4 · 2023: 6 · 2022: 8 · 2021: 2 · 2020: 4 · 2019: 11 · 2018: 9 · 2017: 11 · 2016: 12 · 2015: 12 · 2014: 15 · 2013: 16 · 2012: 10
FWCI
7.05
Type
journal article
Language
en
Open access
closed
Locations
  • Archives of Andrology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords
obesity, men, body mass index, total testosterone, sex hormone-binding globulin, leptin, insulin, insulin resistance, HOMA-IR, waist circumference, sex hormones, estradiol
MeSH terms
Adipose Tissue, Adult, Humans, Insulin, Insulin Resistance, Male, Middle Aged, Obesity, Sex Hormone-Binding Globulin, Testosterone, Body Mass Index, Leptin

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