The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Linear Combinations of Multiple Diagnostic Markers
Abstract
The receiver operating characteristic (ROC) curve is a simple and meaningful measure to assess the usefulness of diagnostic markers. To use the information carried by multiple markers, we note that Fisher's linear discriminant function provides a linear combination of markers to maximize the sensitivity over the entire specificity range uniformly under the multivariate normal distribution model with proportional covariance matrices. With no restriction on covariance matrices, we also provide a solution of the best linear combination of markers in the sense that the area under the ROC curve of this combination is maximized among all possible linear combinations. We illustrate both situations discussed in the article with a cancer clinical trial data.
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The meaning and use of the area under a receiver operating characteristic (ROC) curve.
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THE USE OF MULTIPLE MEASUREMENTS IN TAXONOMIC PROBLEMS
FISHER, R. A. (1936) · Annals of Eugenics · doi:10.1111/j.1469-1809.1936.tb02137.x · Cited by 15,227
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Cited by
Pencina, M. J., D'Agostino, R. B., & Demler, O. V. (2012) · Statistics in Medicine · doi:10.1002/sim.4348 · Cited by 349
Misuse of DeLong test to compare AUCs for nested models
Demler, O. V., Pencina, M. J., & D'Agostino, R. B. (2012) · Statistics in Medicine · doi:10.1002/sim.5328 · Cited by 306
Liu, Z., & Lin, X. (2019) · Journal of the American Statistical Association · doi:10.1080/01621459.2018.1513363 · Cited by 36
A Game Changer for Bipolar Disorder Diagnosis Using RNA Editing-Based Biomarkers
Salvetat, N., Checa-Robles, F. J., Patel, V., Cayzac, C., Dubuc, B., Chimienti, F., Abraham, J.-D., Dupré, P., Vetter, D., Méreuze, S., et al. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-01938-6 · Cited by 31
Calibration of medical diagnostic classifier scores to the probability of disease
Chen, W., Sahiner, B., Samuelson, F., Pezeshk, A., & Petrick, N. (2018) · Statistical Methods in Medical Research · doi:10.1177/0962280216661371 · Cited by 29
Metadata
- Authors
- Su, J. Q., & Liu, J. S.
- Venue
- Journal of the American Statistical Association
- Publisher
- Informa UK Limited
- Published
- 1993-12
- Volume
- 88
- Issue
- 424
- Pages
- 1350-1355
- ISSN
- 0162-1459 (ISSN-L)
- 1537-274X
- OpenAlex
- W2048390639
- Cited by
- 278
- References
- 19
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
