Short-Term Treatment Effects of a Substance Use Disorder Therapy Involving Traditional Amazonian Medicine
Abstract
Chronic illness management today commonly involves alternative medicines. Substance use disorder (SUD), as a chronic psychosomatic illness, might benefit from a similar approach. The accredited Takiwasi Center offers such an SUD treatment program involving Amazonian medicine combined with psychotherapy. The current study assessed this integrative program‘s short-term therapeutic effects. We measured baseline data from 53 dependence-diagnosed males admitted to treatment (T1) and repeated clinical outcome variables at treatment completion (T2). Paired samples t-tests were used to assess changes between T1 and T2 (n = 36). Nearly all participants (age M= 30.86, SD= 8.17) were dependent on multiple substances, most prominently cannabis, alcohol, and cocaine-related drugs. A significant decrease (T1 to T2) was found for addiction severity outcomes drug use (p < .001), alcohol use (p < .001), psychiatric status (p < .001), and social/familial relationships (p < .001). Emotional distress also diminished significantly (p < .001), as did substance craving (p < .001). Quality of life increased significantly from T1 to T2 (p < .001). Our results provide first indications for significantly improved SUD symptoms after the Amazonian medicine-based treatment. These findings are preliminary given the design, but strongly encourage further investigation of this therapy, which in the long term may open new therapeutic avenues for SUDs.
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Ayahuasca or its chemical equivalent pharmahuasca has emerged as a tool for psychotherapy in the contexts of affective and substance use disorders.
“Ayahuasca, or its chemical equivalent known as pharmahuasca, has emerged as a tool for psychotherapy in the contexts of affective and substance use disorders [130,131], thus calling for a better understanding of its possible mechanisms of action.”
From Molecular and Functional Imaging Studies of Psychedelic Drug Action in Animals and Humans. (2021) · cites this paper as [131]
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- Authors
- Berlowitz, I., Walt, H., Ghasarian, C., Mendive, F., & Martin-Soelch, C.
- Affiliations
- University of Fribourg (CH)
- University Hospital Zurich (CH)
- University of Neuchâtel (CH)
- Research Coordination, Takiwasi Addiction Treatment Center, Tarapoto, Peru
- Department of Psychology, University of Fribourg, Fribourg, Switzerland
- Corresponding author
- Berlowitz, Ilana
- Venue
- Journal of Psychoactive Drugs
- Publisher
- Informa UK Limited
- Published
- 2019-05-01
- Volume
- 51
- Issue
- 4
- Pages
- 323-334
- ISSN
- 0279-1072 (ISSN-L)
- 2159-9777
- OpenAlex
- W2942662903
- Cited by
- 72
- References
- 60
- Citations by year
- 2026: 8 · 2025: 13 · 2024: 10 · 2023: 10 · 2022: 12 · 2021: 11 · 2020: 6 · 2019: 1
- FWCI
- 5.71
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Psychoactive Drugs (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (SNSF-148981)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Social Sciences › Psychology › Clinical Psychology › Psychedelics and Drug Studies
- Keywords
- substance use disorders, integrative therapy, traditional medicine, addiction treatment, alcohol consumption, cannabis use, cocaine use, drug craving, emotional distress, quality of life, psychiatric symptoms, interpersonal relationships
- MeSH terms
- Adult, Combined Modality Therapy, Humans, Male, Medicine, Traditional, Psychotherapy, Treatment Outcome, Substance-Related Disorders, Young Adult
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