The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
LABORATORY SYNTHESIS OF POLYETHYLENE GLYCOL DERIVATIVES
Abstract
In recent years, derivatives of polyethylene glycol (PEG) have proven valuable in a variety of diverse chemical and biological endeavors. Such applications include peptide synthesis, phase transfer catalysis, pharmaceutical modification, protein and cell purifications, polymer-bound reagents, and binding assays. Because of the great deal of interest surrounding this subject, this review will describe generally applicable laboratory methods for preparing PEG derivatives from the parent PEG. We have largely restricted discussion to this starting material because most research laboratories interested in applications are not equipped to handle complex ethylene oxide polymerizations used in large-scale industrial preparations and because PEG and some of its ethers and esters are the only commonly available polymeric starting materials. For the purpose of this review, PEG is defined as those polyoxyethylenes having hydroxyl endgroups and a molecular weight of 20,000 daltons or less.
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Cites
Encyclopedia of polymer science and technology
(2003) · Choice Reviews Online · doi:10.5860/choice.41-0674 · Cited by 5,095
National Cancer Institute (2020) · Definitions · doi:10.32388/bz83sn · Cited by 2,981
Determination of free amino groups in proteins by trinitrobenzenesulfonic acid
Habeeb, A. F. S. A. (1966) · Analytical Biochemistry · doi:10.1016/0003-2697(66)90275-2 · Cited by 2,038
Abuchowski, A., van Es, T., Palczuk, N. C., & Davis, F. F. (1977) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)40291-2 · Cited by 1,358
THE UNITED STATES PHARMACOPEIA.
HATCHER, R. A. (1908) · Journal of the American Medical Association · doi:10.1001/jama.1908.25310270030002f · Cited by 1,258
Handbook of Water Soluble Gums and Resins
Davidson, R. L. (1980) · Cited by 1,048
Bailey, F. E., & Koleske, J. (1976) · Cited by 565
Synthesis and characterization of poly(ethylene glycol) derivatives
Harris, J. M., Struck, E. C., Case, M. G., Paley, M. S., Yalpani, M., Van Alstine, J. M., & Brooks, D. E. (1984) · Journal of Polymer Science: Polymer Chemistry Edition · doi:10.1002/pol.1984.170220207 · Cited by 307
Self-citationBeauchamp, C. O., Gonias, S. L., Menapace, D. P., & Pizzo, S. V. (1983) · Analytical Biochemistry · doi:10.1016/0003-2697(83)90131-8 · Cited by 207
Cited by
Effect of pegylation on pharmaceuticals
Harris, J. M., & Chess, R. B. (2003) · Nature Reviews Drug Discovery · doi:10.1038/nrd1033 · Cited by 3,431
Self-citationChemistry for peptide and protein PEGylation
Roberts, M. J., Bentley, M. D., & Harris, J. M. (2002) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(02)00022-4 · Cited by 1,604
Self-citationGene therapy and DNA delivery systems
Ibraheem, D., Elaissari, A., & Fessi, H. (2014) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2013.11.041 · Cited by 454
Chemistry for peptide and protein PEGylation
Roberts, M. J., Bentley, M. D., & Harris, J. M. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.09.025 · Cited by 334
Self-citationZhu, K. J., Xiangzhou, L., & Shilin, Y. (1990) · Journal of Applied Polymer Science · doi:10.1002/app.1990.070390101 · Cited by 313
Metadata
- Authors
- Harris, J. M.
- Venue
- Journal of Macromolecular Science, Part C
- Publisher
- Informa UK Limited
- Published
- 1985-08
- Volume
- 25
- Issue
- 3
- Pages
- 325-373
- ISSN
- 0736-6574 (ISSN-L)
- 1532-1797
- 1520-5746
- OpenAlex
- W1973656016
- Cited by
- 267
- References
- 26
- FWCI
- 12.50
- Type
- journal article
- Language
- en
- Open access
- closed
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- Harris, J. M. (1985). LABORATORY SYNTHESIS OF POLYETHYLENE GLYCOL DERIVATIVES. Journal of Macromolecular Science, Part C. https://doi.org/10.1080/07366578508081960
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
