The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Resveratrol, a phenolic antioxidant with effects on blood platelet functions
Abstract
The main purpose of this article is to provide an overview of the currently available evidence of antiplatelet properties of resveratrol (3,4('),5-trihydroxystilbene). Resveratrol, a phenolic compound found naturally in fruits, nuts, flowers, seeds and bark of different plants is integral part of human diet. It exhibits a wide range of biological effects, including antiplatelet, anti-inflammatory, anticancer, antimutagenic and antifungal properties. It is also a potent antioxidant, reactive oxygen species scavenger and metal chelators. Resveratrol reduces lipid peroxidation, oxidation and nitration of platelet and plasma proteins. This review article describes the chemical structure of resveratrol, its biological activity, the effects on blood platelet functions and the mechanisms involved in its action on blood platelets, the cells which play an important role not only in the haemostatic process, but also in pathogenesis of cardiovascular diseases.
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Cites
Cancer chemopreventive activity of resveratrol, a natural product derived from grapes
Jang, M., Cai, L., Udeani, G. O., Slowing, K. V., Thomas, C. F., Beecher, C. W. W., Fong, H. H. S., Farnsworth, N. R., Kinghorn, A. D., Mehta, R. G., et al. (1997) · Science · doi:10.1126/science.275.5297.218 · Cited by 4,935
Cited by
Interaction of β-Lactoglobulin with Resveratrol and its Biological Implications
Liang, L., Tajmir-Riahi, H. A., & Subirade, M. (2008) · Biomacromolecules · doi:10.1021/bm700728k · Cited by 472
Polyphenols: Benefits to the Cardiovascular System in Health and in Aging
Khurana, S., Venkataraman, K., Hollingsworth, A., Piche, M., & Tai, T. (2013) · Nutrients · doi:10.3390/nu5103779 · Cited by 434
Ji, Q., Liu, X., Fu, X., Zhang, L., Sui, H., Zhou, L., Sun, J., Cai, J., Qin, J., Ren, J., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0078700 · Cited by 354
RetractedWong, R. H. X., Howe, P. R. C., Buckley, J. D., Coates, A. M., Kunz, I., & Berry, N. M. (2011) · Nutrition, Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2010.03.003 · Cited by 277
Baxter, R. A. (2008) · Journal of Cosmetic Dermatology · doi:10.1111/j.1473-2165.2008.00354.x · Cited by 263
Metadata
- Authors
- Olas, B., & Wachowicz, B.
- Venue
- Platelets
- Publisher
- Informa UK Limited
- Published
- 2005-08
- Volume
- 16
- Issue
- 5
- Pages
- 251-260
- ISSN
- 0953-7104 (ISSN-L)
- 1369-1635
- OpenAlex
- W2050263998
- Cited by
- 180
- References
- 1
- FWCI
- 4.57
- Type
- journal article
- Language
- en
- Open access
- closed
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- Olas, B., & Wachowicz, B. (2005). Resveratrol, a phenolic antioxidant with effects on blood platelet functions. Platelets. https://doi.org/10.1080/09537100400020591
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
