Mental health problems in people living with HIV: changes in the last two decades: the London experience 1990–2014
Open accessAbstract
Mental health problems continue to be a significant comorbidity for people with HIV infection, even in the era of effective antiretroviral therapy. Here, we report on the changes in the mental health diagnoses based on clinical case reports amongst people with HIV referred to a specialist psychological medicine department over a 24-year period, which include the relative increase in depressive and anxiety disorders, often of a chronic nature, together with a decline in acute mental health syndromes, mania, and organic brain disorders. In addition, new challenges, like the presence of HIV and Hepatitis C co-infection, and the new problems created by recreational drugs, confirm the need for mental health services to be closely involved with the general medical services. A substantial proportion of people with HIV referred to specialist services suffer complex difficulties, which often require the collaboration of both psychiatrists and psychologists to deal effectively with their difficulties.
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In agreement with previous literature, the frequency of anxiety disorders, depression, problematic alcohol and other substance use, and suicidal behavior is particularly high among people living with HIV in the study sample.
“Σε συμφωνία με την προηγούμενη βιβλιογραφία γύρω από τις ψυχιατρικές εκδηλώσεις στη λοίμωξη HIV, 7-10 στο δείγμα της παρούσας έρευνας βρέθηκε ότι η συχνότητα των αγχωδών διαταραχών, της κατάθλιψης, της προβληματικής χρήσης αλκοόλ και άλλων ψυχοτρόπων ουσιών και της αυτοκτονικής συμπεριφοράς είναι ιδιαίτερα υψηλή μεταξύ των ανθρώπων που ζουν με HIV.”
From Clinical presentation and requests for support of people with HIV/AIDS seeking counselling and psychotherapy in Greece (2019) · cites this paper as [7]
The Results (Principal psychiatric diagnosis; Recreational drug use; pages unavailable) report depression, anxiety disorders, and substance misuse among patients with HIV referred to a specialist service. They list alcohol use but do not establish a high frequency of problematic alcohol use, and the searched passages do not address suicidal behavior. The cited paper also cannot substantiate the frequencies in the citing authors’ own study sample. (LLM, conf=0.84)
Experimental — accuracy not yet measuredMental disorders are the most common comorbidities in HIV infection.
“Οι ψυχικές διαταραχές, πιο συγκεκριμένα, παραμένουν έως και σήμερα οι συχνότερες συννοσηρότητες στη λοίμωξη HIV, με ποσοστά επίπτωσης που έχουν εκτιμηθεί έως και στο 50%, πολύ υψηλότερα σε σχέση με τον γενικό πληθυσμό και με ομάδες ανθρώπων που πάσχουν από άλλα χρόνια νοσήματα. 7-9”
From Clinical presentation and requests for support of people with HIV/AIDS seeking counselling and psychotherapy in Greece (2019) · cites this paper as [7]
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Cites
HIV and Depression – a systematic review of interventions
Sherr, L., Clucas, C., Harding, R., Sibley, E., & Catalan, J. (2011) · Psychology, Health & Medicine · doi:10.1080/13548506.2011.579990 · Cited by 325 · see citing works
Chesney, M. A., Chambers, D. B., Taylor, J. M., Johnson, L. M., & Folkman, S. (2003) · Psychosomatic Medicine · doi:10.1097/01.psy.0000097344.78697.ed · Cited by 299 · see citing works
Hirshfield, S., Remien, R. H., Humberstone, M., Walavalkar, I., & Chiasson, M. A. (2004) · AIDS Care · doi:10.1080/09540120412331292525 · Cited by 258 · see citing works
Hepatitis C infection, antiviral treatment and mental health: A European expert consensus statement
Schaefer, M., Capuron, L., Friebe, A., Diez-Quevedo, C., Robaeys, G., Neri, S., Foster, G. R., Kautz, A., Forton, D., & Pariante, C. M. (2012) · Journal of Hepatology · doi:10.1016/j.jhep.2012.07.037 · Cited by 225 · see citing works
The methamphetamine epidemic: Implications for HIV prevention and treatment
Colfax, G. N., & SHOPTAW, S. J. (2005) · Current HIV/AIDS Reports · doi:10.1007/s11904-005-0016-4 · Cited by 215 · see citing works
Kendall, C. E., Wong, J., Taljaard, M., Glazier, R. H., Hogg, W., Younger, J., & Manuel, D. G. (2014) · BMC Public Health · doi:10.1186/1471-2458-14-161 · Cited by 213 · see citing works
Crystal methamphetamine and sexual sociality in an urban gay subculture: An elective affinity
Green, A. I., & Halkitis, P. N. (2006) · Culture Health & Sexuality · doi:10.1080/13691050600783320 · Cited by 196 · see citing works
Review of treatment studies of depression in HIV.
Olatunji, B. O., Mimiaga, M. J., O’Cleirigh, C. M., & Safren, S. A. (2006) · PubMed · Cited by 106 · see citing works
Sexual Marathons and Methamphetamine Use among HIV-Positive Men Who Have Sex with Men
Semple, S. J., Zians, J., Strathdee, S. A., & Patterson, T. L. (2008) · Archives of Sexual Behavior · doi:10.1007/s10508-007-9292-y · Cited by 103 · see citing works
A systematic review of interventions for anxiety in people with HIV
Clucas, C., Sibley, E., Harding, R., Liu, L., Catalan, J., & Sherr, L. (2011) · Psychology, Health & Medicine · doi:10.1080/13548506.2011.579989 · Cited by 81 · see citing works
Comprehensive Textbook of AIDS Psychiatry
Sudak, D. M. (2008) · Psychosomatics · doi:10.1176/appi.psy.49.4.365 · Cited by 51 · see citing works
Sex Like You Can't Even Imagine: “Crystal,” Crack and Gay Men
Guss, J. R. (2000) · Journal of Gay & Lesbian Psychotherapy · doi:10.1300/j236v03n03_09 · Cited by 36 · see citing works
The changing pattern of mental health problems in HIV infection: The view from London, UK
Catalan, J. M., Meadows, J., & Douzenis, A. (2000) · AIDS Care · doi:10.1080/09540120050042990 · Cited by 35 · see citing works
Comprehensive Textbook of AIDS Psychiatry
(2017) · doi:10.1093/med/9780199392742.001.0001 · Cited by 31 · see citing works
Psychological medicine of HIV infection
Catalán, J., Burgess, A., & Klimeš, I. (1995) · Oxford University Press eBooks · Cited by 29 · see citing works
Psychological medicine of HIV infection
Salt, M. H. (1996) · Journal of Psychosomatic Research · doi:10.1016/0022-3999(96)00028-1 · Cited by 27 · see citing works
Psychosocial Issues and Mental Health Treatment Recommendations for Patients With Hepatitis C
Silberbogen, A. K., Ulloa, E. W., Janke, E. A., & Mori, D. L. (2009) · Psychosomatics · doi:10.1176/appi.psy.50.2.114 · Cited by 25 · see citing works
Multimorbidity among people with HIV in regional New South Wales, Australia
Edmiston, N., Passmore, E., Smith, D. J., & Petoumenos, K. (2015) · Sexual Health · doi:10.1071/sh14070 · Cited by 22 · see citing works
(2005) · Cambridge University Press eBooks · doi:10.1017/cbo9780511543586 · Cited by 4 · see citing works
Joska, J. A., Stein, D. J., & Grant, I. (2014) · Cited by 3 · see citing works
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Mossie, T. B., Takelle, G. M., & Yemiyamrew, E. (2017) · Ethiopian Journal of Health Sciences · doi:10.4314/ejhs.v27i1.9 · Cited by 48 · see citing works
Jallow, A., Ljunggren, G., Wändell, P. E., Wahlström, L., & Carlsson, A. C. (2016) · Journal of Infection · doi:10.1016/j.jinf.2016.09.009 · Cited by 41 · see citing works
Woodgate, R. L., Zurba, M., Tennent, P., Cochrane, C., Payne, M., & Mignone, J. (2017) · Social Science & Medicine · doi:10.1016/j.socscimed.2017.10.002 · Cited by 38 · see citing works
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Zhu, J., Ananthan, S., & Zhan, C. (2017) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2017.10.007 · Cited by 30 · see citing works
Nguyen, M. X., Go, V. F.-L., Bui, Q., Gaynes, B. N., & Pence, B. W. (2019) · Harm Reduction Journal · doi:10.1186/s12954-019-0349-8 · Cited by 28 · see citing works
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Nguyen, M. X., Reyes, H. L. M., Pence, B. W., Muessig, K. E., Hutton, H. E., Latkin, C. A., Dowdy, D. W., Chander, G., Lancaster, K. E., Frangakis, C., et al. (2021) · Journal of the International AIDS Society · doi:10.1002/jia2.25746 · Cited by 17 · see citing works
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Özdemir, H. Ö., Tosun, S. Y., Özdemir, D., & Tümer, E. K. (2019) · American Journal of Industrial Medicine · doi:10.1002/ajim.23056 · Cited by 14 · see citing works
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Grelotti, D. J., Hammer, G. P., Dilley, J., Karasic, D. H., Sorensen, J. L., Bangsberg, D. R., & Tsai, A. C. (2016) · AIDS Care · doi:10.1080/09540121.2016.1226479 · Cited by 11 · see citing works
Smith, D., Woolley, I. J., Russell, D., Bisshop, F., & Furner, V. (2018) · HIV Medicine · doi:10.1111/hiv.12637 · Cited by 11 · see citing works
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Conway, F. N., Rountree, M., & Jones, K. V. (2021) · Community Mental Health Journal · doi:10.1007/s10597-020-00756-8 · Cited by 10 · see citing works
Abdulai, M., Owiredu, D., Boadu, I., Tabong, P. T., Sarfo, B. Y., Bonful, H. A., Addo-Lartey, A. A., Akuffo, K. O., & Danso‐Appiah, A. (2023) · PLoS ONE · doi:10.1371/journal.pone.0291781 · Cited by 9 · see citing works
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Torales, J. C., González, I., Barrios, I., Ventriglio, A., & Bhugra, D. (2018) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0000000000000875 · Cited by 8 · see citing works
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Aboobaker, A., Zingela, Z., & Adeniyi, O. V. (2022) · South African Journal of Psychiatry · doi:10.4102/sajpsychiatry.v28i0.1753 · Cited by 2 · see citing works
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- Authors
- Adams, C., Zacharia, S., Masters, L., Coffey, C., & Catalan, P.
- Corresponding author
- Adams, Catherine
- ORCID
- Coffey, Caroline
- Venue
- AIDS Care
- Publisher
- Informa UK Limited
- Published
- 2016-02-17
- Volume
- 28
- Issue
- sup1
- Pages
- 56-59
- ISSN
- 0954-0121 (ISSN-L)
- 1360-0451
- PMC
- PMC4828597
- OpenAlex
- W2332416385
- Cited by
- 50
- References
- 20
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 4 · 2023: 7 · 2022: 3 · 2021: 5 · 2020: 2 · 2019: 10 · 2018: 5 · 2017: 5 · 2016: 4
- FWCI
- 7.39
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- AIDS Care (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Health Sciences › Medicine › Emergency Medicine › HIV-related health complications and treatments
- Health Sciences › Medicine › Epidemiology › HIV, Drug Use, Sexual Risk
- Keywords
- HIV, psychiatric comorbidity, depressive disorders, anxiety disorders, chronic mental illness, mania, organic brain disease, recreational drug use, antiretroviral therapy era
- MeSH terms
- Adult, Anxiety Disorders, Mental Disorders, Bipolar Disorder, Depressive Disorder, Female, Hepatitis C, Humans, London, Male, Mental Health, Mental Health Services, Middle Aged, Referral and Consultation, HIV Infections, Comorbidity, Substance-Related Disorders, Sexual Dysfunctions, Psychological, Coinfection
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