The DOI matches its Crossref record; 48 of the 48 references it cites were found in a registry or an index.
Surface Plasmon Resonance (SPR) Biosensors in Pharmaceutical Analysis
Abstract
This review aims to highlight the applications of one of the most prominent optical biosensor technologies, surface plasmon resonance (SPR), in the drug discovery process and quality analysis of pharmaceutical compounds and their particularities. SPR assay formats and experimental issues are used for pharmacokinetic drug profiling, ADMET studies, high-throughput screening, and fragment-based drug screening, the last with an emphasis on the detection of small (drug) molecules. The classical method strengths and some applications of localized SPR and SPR imaging that are of high interest in the drug discovery process are presented, as well as possible challenges. While similar works treat separately the steps of drug discovery or focus only on the detection of drug residues in food or health safety, this review presents in a compact format the results and the progress obtained in both areas (drug discovery and quality analysis) based on the application of SPR biosensors.
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Cites
Biosensors: sense and sensibility
Turner, A. P. F. (2013) · Chemical Society Reviews · doi:10.1039/c3cs35528d · Cited by 1,654
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Surface plasmon resonance based biosensor technique: A review
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Mechanisms of Drug Toxicity and Relevance to Pharmaceutical Development
Guengerich, F. P. (2011) · Drug Metabolism and Pharmacokinetics · doi:10.2133/dmpk.dmpk-10-rv-062 · Cited by 387
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New trends in instrumental design for surface plasmon resonance-based biosensors
Abbas, A., Linman, M. J., & Cheng, Q. (2011) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2010.09.030 · Cited by 301
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Cited by
SERS-Activated Platforms for Immunoassay: Probes, Encoding Methods, and Applications
Wang, Z., Zong, S., Wu, L., Zhu, D., & Cui, Y. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00027 · Cited by 614
Biophysics in drug discovery: impact, challenges and opportunities
Renaud, J.-P., Chung, C.-W., Danielson, U. H., Egner, U., Hennig, M., Hubbard, R. E., & Nar, H. (2016) · Nature Reviews Drug Discovery · doi:10.1038/nrd.2016.123 · Cited by 382
Ion mobility in the pharmaceutical industry: an established biophysical technique or still niche?
Campuzano, I. D., & Lippens, J. L. (2018) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2017.11.008 · Cited by 42
Action mechanism of a novel agrichemical quinofumelin against Fusarium graminearum
Xiu, Q., Yin, X., Chen, Y., Zhang, Z., Mao, Y., Wang, T., Zhang, J., Zhou, M., & Duan, Y. (2025) · eLife · doi:10.7554/elife.105892.3 · Cited by 11
Action mechanism of a novel agrichemical quinofumelin against Fusarium graminearum
Xiu, Q., Yin, X., Chen, Y., Zhang, Z., Mao, Y., Wang, T., Zhang, J., Zhou, M., & Duan, Y. (2025) · eLife · doi:10.7554/elife.105892 · Cited by 1
Metadata
- Authors
- Olaru, A., Bala, C., Jaffrezic-Renault, N., & Aboul-Enein, H. Y.
- Venue
- Critical Reviews in Analytical Chemistry
- Publisher
- Informa UK Limited
- Published
- 2015-01-06
- Volume
- 45
- Issue
- 2
- Pages
- 97-105
- ISSN
- 1040-8347 (ISSN-L)
- 1547-6510
- OpenAlex
- W2070784177
- Cited by
- 400
- References
- 48
- FWCI
- 6.21
- Type
- journal article
- Language
- en
- Open access
- closed
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- Olaru, A., Bala, C., Jaffrezic-Renault, N., & Aboul-Enein, H. Y. (2015). Surface Plasmon Resonance (SPR) Biosensors in Pharmaceutical Analysis. Critical Reviews in Analytical Chemistry. https://doi.org/10.1080/10408347.2014.881250
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