The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Antimicrobial activity of eugenol and essential oils containing eugenol: A mechanistic viewpoint
Abstract
Eugenol is a hydroxyphenyl propene, naturally occurring in the essential oils of several plants belonging to the Lamiaceae, Lauraceae, Myrtaceae, and Myristicaceae families. It is one of the major constituents of clove (Syzygium aromaticum (L.) Merr. & L.M. Perry, Myrtaceae) oil and is largely used in both foods and cosmetics as a flavoring agent. A large body of recent scientific evidence supports claims from traditional medicine that eugenol exerts beneficial effects on human health. These effects are mainly associated with antioxidant and anti-inflammatory activities. Eugenol has also shown excellent antimicrobial activity in studies, being active against fungi and a wide range of gram-negative and gram-positive bacteria. The aim of this review is to analyze scientific data from the main published studies describing the antibacterial and antifungal activities of eugenol targeting different kind of microorganisms, such as those responsible for human infectious diseases, diseases of the oral cavity, and food-borne pathogens. This article also reports the effects of eugenol on multi-drug resistant microorganisms. On the basis of this collected data, eugenol represents a very interesting bioactive compound with broad spectrum antimicrobial activity against both planktonic and sessile cells belonging to food-decaying microorganisms and human pathogens.
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Cites
Essential oils: Their antibacterial properties and potential applications in foods—A review
Burt, S. (2004) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2004.03.022 · Cited by 10,488
Effect of essential oils on pathogenic bacteria
Nazzaro, F., Fratianni, F., De Martino, L., Coppola, R., & De Feo, V. (2013) · Pharmaceuticals · doi:10.3390/ph6121451 · Cited by 2,186 · cited 1×
“Mechanism of action of eugenol on bacteria The antimicrobial activity of eugenol can be ascribed to the presence of a free hydroxyl group in the molecule (Nazzaro et al., 2013).”
BackgroundMembrane toxicity of antimicrobial compounds from essential oils
Di Pasqua, R., Betts, G., Hoskins, N., Edwards, M., Ercolini, D., & Mauriello, G. (2007) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf0636465 · Cited by 648
Khan, M. S. A., Zahin, M., Hasan, S., Husain, F. M., & Ahmad, I. (2009) · Letters in Applied Microbiology · doi:10.1111/j.1472-765x.2009.02666.x · Cited by 279
Laekeman, G. M., van Hoof, L., Haemers, A., Berghe, D. A. V., Herman, A. G., & Vlietinck, A. J. (1990) · Phytotherapy Research · doi:10.1002/ptr.2650040304 · Cited by 89
Aegle marmelos (L.) Correa (Bael) and Its Phytochemicals in the Treatment and Prevention of Cancer
Baliga, M. S., Thilakchand, K. R., Rai, M. P., Rao, S., & Venkatesh, P. (2013) · Integrative Cancer Therapies · doi:10.1177/1534735412451320 · Cited by 63 · cited 2×
“In addition to the aforementioned clove, basil, and cinnamon species, the presence of eugenol has been reported at varying ratios in the EOs of a number of plant species, e.g. Myristica fragrans Houtt., Melissa officinalis L., Illicium anisatum (Jaganathan & Supriyanto, 2012), Aphanamixis polystachya (Shaikh et al., 2…”
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Cited by
Quality Control of the Traditional Herbs and Herbal Products: A Review
Balekundri, A., & Mannur, V. (2020) · Future Journal of Pharmaceutical Sciences · doi:10.1186/s43094-020-00091-5 · Cited by 252
Melo, R. S., Albuquerque Azevedo, Á. M., Gomes Pereira, A. M., Rocha, R. R., Bastos Cavalcante, R. M., Carneiro Matos, M. N., Ribeiro Lopes, P. H., Gomes, G. A., Soares Rodrigues, T. H., Santos, H. S. D., et al. (2019) · Molecules · doi:10.3390/molecules24213864 · Cited by 106
The natural product eugenol is an inhibitor of the ebola virus in vitro
Lane, T., Anantpadma, M., Freundlich, J. S., Davey, R. A., Madrid, P. B., & Ekins, S. (2019) · Pharmaceutical Research · doi:10.1007/s11095-019-2629-0 · Cited by 88
Herbs that heal: Nature’s pharmacy endowed remedies for better health
Mehrotra, N. (2021) · Annals of Phytomedicine: An International Journal · doi:10.21276/ap.2021.10.1.2 · Cited by 27
Eugenol restrains abdominal aortic aneurysm progression with down‐regulations on NF‐κB and COX‐2
Zhai, Z., Zhang, X., Ding, Y., Huang, Z., Li, Q., Zheng, M., Cho, K., Dong, Z., Fu, W., Chen, Z., et al. (2022) · Phytotherapy Research · doi:10.1002/ptr.7358 · Cited by 23
Metadata
- Authors
- Marchese, A., Barbieri, R., Coppo, E., Orhan, I. E., Daglia, M., Nabavi, S. F., Izadi, M., Abdollahi, M., Nabavi, S. M., & Ajami, M.
- Venue
- Critical Reviews in Microbiology
- Publisher
- Informa UK Limited
- Published
- 2017-03-27
- Volume
- 43
- Issue
- 6
- Pages
- 668-689
- ISSN
- 1040-841X (ISSN-L)
- 1549-7828
- OpenAlex
- W2599029674
- Cited by
- 750
- References
- 6
- FWCI
- 36.08
- Type
- journal article
- Language
- en
- Open access
- closed
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- Marchese, A., Barbieri, R., Coppo, E., Orhan, I. E., Daglia, M., Nabavi, S. F., Izadi, M., Abdollahi, M., Nabavi, S. M., & Ajami, M. (2017). Antimicrobial activity of eugenol and essential oils containing eugenol: A mechanistic viewpoint. Critical Reviews in Microbiology. https://doi.org/10.1080/1040841x.2017.1295225
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