The Concordance Correlation Coefficient for Repeated Measures Estimated by Variance Components
Abstract
The concordance correlation coefficient (CCC) is an index that is commonly used to assess the degree of agreement between observers on measuring a continuous characteristic. Here, a CCC for longitudinal repeated measurements is developed through the appropriate specification of the intraclass correlation coefficient from a variance components linear mixed model. A case example and the results of a simulation study are provided.
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If available, test-retest data are extremely helpful, as they can help prioritize features on the basis of their reproducibility.
“If available, test-retest data are also extremely helpful, as they can help prioritize features on the basis of their reproducibility (51,52).”
From Radiomics: Images Are More than Pictures, They Are Data (2016) · cites this paper as [52]
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Rasulo, F. A., Calza, S., Robba, C., Taccone, F. S., Biasucci, D. G., Badenes, R., Piva, S., Savo, D., Citerio, G., Dibu, J. R., et al. (2022) · Figshare · doi:10.6084/m9.figshare.19607665
- Authors
- Carrasco, J. L., King, T. S., & Chinchilli, V. M.
- Affiliations
- Universitat de Barcelona (ES)
- Pennsylvania State University (US)
- Corresponding author
- Carrasco, Josep L.
- Venue
- Journal of Biopharmaceutical Statistics
- Publisher
- Informa UK Limited
- Published
- 2009-01-02
- Volume
- 19
- Issue
- 1
- Pages
- 90-105
- ISSN
- 1054-3406 (ISSN-L)
- 1520-5711
- OpenAlex
- W2149541891
- Cited by
- 111
- References
- 13
- Citations by year
- 2026: 8 · 2025: 10 · 2024: 8 · 2023: 3 · 2022: 14 · 2021: 10 · 2020: 9 · 2019: 5 · 2018: 9 · 2017: 11 · 2016: 3 · 2015: 4 · 2014: 2 · 2013: 6 · 2012: 1
- FWCI
- 3.71
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Biopharmaceutical Statistics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Reliability and Agreement in Measurement
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods and Bayesian Inference
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Clinical Trials
- Keywords
- concordance correlation coefficient, repeated measures, intraclass correlation coefficient, variance components, linear mixed models, interobserver agreement, longitudinal data, measurement agreement
- MeSH terms
- Algorithms, Analysis of Variance, Computer Simulation, Pharmaceutical Preparations, Humans, Hydrocortisone, Pharmacokinetics, Models, Statistical, Observer Variation, Confidence Intervals, Linear Models, Area Under Curve
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