Cited by 80Dementia and Cognitive Impairment ResearchHealth disparities and outcomesAging, Health, and Disability

Bridging the divide between biomedical and psychosocial approaches in dementia research: the 2019 INTERDEM manifesto

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Vernooij-Dassen, Myrra, Moniz-Cook, Esme, Verhey, Frans, Chattat, Rabih, Woods, Bob, Meiland, Franka, Franco, Manuel, Holmerova, Iva +2 more·2021·Aging & Mental Health

Abstract

OBJECTIVE: To provide a new perspective on integrated biomedical and psychosocial dementia research. BACKGROUND: Dementia is being recognized as a multifactorial syndrome, but there is little interaction between biomedical and psychosocial approaches. A way to improve scientific knowledge is to seek better understanding of the mechanisms underlying the interaction between biomedical and psychosocial paradigms. One rationale for integrating biomedical and psychosocial research is the discordance between neuropathology and cognitive functioning. The concept of social health might bridge the two paradigms. It relates to how social resources influence the dynamic balance between capacities and limitations. HYPOTHESES: Social health can act as the driver for accessing cognitive reserve, in people with dementia through active facilitation and utilization of social and environmental resources. Thereby we link lifestyle social and opportunities to the brain reserve hypothesis. MANIFESTO: We provide a Manifesto on how to significantly move forward the dementia research agenda.

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Crossref · 10.1080/13607863.2019.1693968

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Authors
Vernooij-Dassen, M., Moniz-Cook, E., Verhey, F., Chattat, R., Woods, B., Meiland, F., Franco, M., Holmerova, I., Orrell, M., & de Vugt, M.
Affiliations
  • Radboud University Medical Center (NL)
  • University of Hull (GB)
  • Maastricht University Medical Centre (NL)
  • University of Bologna (IT)
  • Bangor University (GB)
  • Amsterdam University Medical Centers (NL)
  • Hospital Universitario Río Hortega (ES)
  • Charles University FHS CELLO and Gerontologicke Centrum, Kobylisy, Czechia
  • University of Nottingham (GB)
  • Alzheimer Center Limburg, School for Mental Health and Neurosciences, Maastricht University, Maastricht, the Netherlands
Corresponding author
Vernooij-Dassen, Myrra
Venue
Aging & Mental Health
Published
2019-11-26
Volume
25
Issue
2
Pages
206-212
ISSN
  • 1360-7863 (ISSN-L)
  • 1364-6915
OpenAlex
W2986491747
Cited by
80
References
50
Citations by year
2026: 5 · 2025: 8 · 2024: 18 · 2023: 9 · 2022: 14 · 2021: 22 · 2020: 4
FWCI
7.96
Type
journal article
Language
en
Open access
Locations
  • Aging & Mental Health (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
  • Gredos (University of Salamanca) (publishedVersion, cc-by-nc-nd)
  • Hispana (publishedVersion, cc-by-nc-nd)
  • Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion, other-oa)
  • Repository@Hull (Worktribe) (University of Hull) (submittedVersion, other-oa)
  • Research Publications (Maastricht University) (submittedVersion, cc-by-nc-nd)
  • Archivio istituzionale della ricerca (Alma Mater Studiorum Università di Bologna) (submittedVersion, cc-by)
  • Repository@Hull (Worktribe) (University of Hull) (submittedVersion, cc-by-nc-nd)
  • Radboud Repository (Radboud University) (submittedVersion)
  • INFM-OAR (INFN Catania) (submittedVersion, cc-by-nc-nd)
  • Radboud Repository (Radboud University) (submittedVersion, other-oa)
  • Research Publications (Maastricht University) (submittedVersion, other-oa)
  • Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
  • Zenodo (CERN European Organization for Nuclear Research) (cc-by)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
  • Social Sciences › Health › Health disparities and outcomes
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Aging, Health, and Disability
Keywords
dementia, social health, cognitive reserve, social resources, lifestyle, research agenda
MeSH terms
Dementia, Humans, Cognitive Reserve

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