Bridging the divide between biomedical and psychosocial approaches in dementia research: the 2019 INTERDEM manifesto
Open accessAbstract
OBJECTIVE: To provide a new perspective on integrated biomedical and psychosocial dementia research. BACKGROUND: Dementia is being recognized as a multifactorial syndrome, but there is little interaction between biomedical and psychosocial approaches. A way to improve scientific knowledge is to seek better understanding of the mechanisms underlying the interaction between biomedical and psychosocial paradigms. One rationale for integrating biomedical and psychosocial research is the discordance between neuropathology and cognitive functioning. The concept of social health might bridge the two paradigms. It relates to how social resources influence the dynamic balance between capacities and limitations. HYPOTHESES: Social health can act as the driver for accessing cognitive reserve, in people with dementia through active facilitation and utilization of social and environmental resources. Thereby we link lifestyle social and opportunities to the brain reserve hypothesis. MANIFESTO: We provide a Manifesto on how to significantly move forward the dementia research agenda.
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Social connections are theorised to contribute to cognitive reserve.
“social connections are theorised to contribute to cognitive reserve,5”
From Associations between social connections and cognition: a global collaborative individual participant data meta-analysis (2022) · cites this paper as [5]
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- Authors
- Vernooij-Dassen, M., Moniz-Cook, E., Verhey, F., Chattat, R., Woods, B., Meiland, F., Franco, M., Holmerova, I., Orrell, M., & de Vugt, M.
- Affiliations
- Radboud University Medical Center (NL)
- University of Hull (GB)
- Maastricht University Medical Centre (NL)
- University of Bologna (IT)
- Bangor University (GB)
- Amsterdam University Medical Centers (NL)
- Hospital Universitario Río Hortega (ES)
- Charles University FHS CELLO and Gerontologicke Centrum, Kobylisy, Czechia
- University of Nottingham (GB)
- Alzheimer Center Limburg, School for Mental Health and Neurosciences, Maastricht University, Maastricht, the Netherlands
- Corresponding author
- Vernooij-Dassen, Myrra
- ORCID
- Venue
- Aging & Mental Health
- Publisher
- Informa UK Limited
- Published
- 2019-11-26
- Volume
- 25
- Issue
- 2
- Pages
- 206-212
- ISSN
- 1360-7863 (ISSN-L)
- 1364-6915
- OpenAlex
- W2986491747
- Cited by
- 80
- References
- 50
- Citations by year
- 2026: 5 · 2025: 8 · 2024: 18 · 2023: 9 · 2022: 14 · 2021: 22 · 2020: 4
- FWCI
- 7.96
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Aging & Mental Health (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Gredos (University of Salamanca) (publishedVersion, cc-by-nc-nd)
- Hispana (publishedVersion, cc-by-nc-nd)
- Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion, other-oa)
- Repository@Hull (Worktribe) (University of Hull) (submittedVersion, other-oa)
- Research Publications (Maastricht University) (submittedVersion, cc-by-nc-nd)
- Archivio istituzionale della ricerca (Alma Mater Studiorum Università di Bologna) (submittedVersion, cc-by)
- Repository@Hull (Worktribe) (University of Hull) (submittedVersion, cc-by-nc-nd)
- Radboud Repository (Radboud University) (submittedVersion)
- INFM-OAR (INFN Catania) (submittedVersion, cc-by-nc-nd)
- Radboud Repository (Radboud University) (submittedVersion, other-oa)
- Research Publications (Maastricht University) (submittedVersion, other-oa)
- Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
- Zenodo (CERN European Organization for Nuclear Research) (cc-by)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Social Sciences › Health › Health disparities and outcomes
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Aging, Health, and Disability
- Keywords
- dementia, social health, cognitive reserve, social resources, lifestyle, research agenda
- MeSH terms
- Dementia, Humans, Cognitive Reserve
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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