Self-Rated Depression Severity Relative to Clinician-Rated Depression Severity: Trait Stability and Potential Role in Familial Transmission of Suicidal Behavior
Open accessAbstract
Self-rated depression and hopelessness severity are predictors of suicide attempt in major depression. This study evaluated whether: (1) greater self-rated distress relative to severity of clinician-rated depression is a trait; (2) that trait is familial; and (3) that trait is linked to familial transmission of suicidal behavior. A total of 285 mood disorder probands and 457 offspring were assessed twice, at least 1 year apart. Family and subject intra-class correlations for self-report depression and hopelessness, controlling for clinician-rated depression severity, were computed. Mixed general linear models determined offspring-proband correlations. Within-individual intra-class correlation (ICC) for depression-hopelessness was 37.8% (bootstrap 95% CI: 31.0-46.3%). Parent-offspring ICC was 10.7% (bootstrap 95% CI: 3.5-17.8%). Suicide attempt concordant parent-offspring correlation for subjective depression was positive, but negative for attempter parent and nonattempter offspring (p = .0213 for slope interaction). Pessimism was greater in proband or offspring attempters than proband or offspring nonattempters (p < .05). Self-reported hopelessness is partly trait-dependent, and there is modest familial transmission of self-reported depression linked to suicidal behavior that may partly explain familial transmission of suicidal behavior.
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Subjective distress is linked to familial transmission of suicidal behavior and includes hopelessness and subjective depression, which are more severe in depressed suicide attempters than in depressed nonattempters.
“- Subjective distress is linked to familial transmission of suicidal behavior and encompasses hopelessness and subjective depression, which are more severe in depressed suicide attempters compared with depressed nonattempters (27).”
From A brain-centric model of suicidal behavior (2020) · cites this paper as [27]
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- Authors
- John Mann, J., Ellis, S. P., Currier, D., Zelazny, J., Birmaher, B., Oquendo, M. A., Kolko, D. J., Stanley, B., Melhem, N., Burke, A. K., & Brent, D. A.
- Affiliations
- New York State Psychiatric Institute (US)
- The University of Melbourne (AU)
- University of Pittsburgh (US)
- ORCID
- Venue
- Archives of Suicide Research
- Publisher
- Informa UK Limited
- Published
- 2016-04-04
- Volume
- 20
- Issue
- 3
- Pages
- 412-425
- ISSN
- 1381-1118 (ISSN-L)
- 1543-6136
- PMC
- PMC8451948
- OpenAlex
- W2318643681
- Cited by
- 10
- References
- 52
- Citations by year
- 2024: 1 · 2022: 2 · 2021: 2 · 2020: 3 · 2019: 1 · 2018: 1
- FWCI
- 0.89
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Archives of Suicide Research (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (R10MH056390, R01MH048514, R01MH056390, P50MH062185, R01MH108039)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- self-rated depression, hopelessness, trait stability, suicide attempts, major depressive disorder, pessimism, intra-class correlation, subjective distress
- MeSH terms
- Pessimism, Adolescent, Adult, Child, Computer Simulation, Major Depressive Disorder, Disease Susceptibility, Family Health, Female, Humans, Male, Medical History Taking, Parents, Psychiatric Status Rating Scales, Risk Factors, Self-Assessment, Suicide, Attempted, Child of Impaired Parents, Suicidal Ideation
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