The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Measurement of antioxidant ability of melatonin and serotonin by the DMPD and CUPRAC methods as trolox equivalent
Open accessAbstract
Melatonin (N-acetyl-5-methoxytryptamine) is the chief secretory product of the pineal gland and synthesized enzymatically from serotonin (5-hydroxytryptamine). These indoleamine derivatives play an important role in the prevention of oxidative damage. In the present study, DMPD radical scavenging and cupric ion (Cu(2+)) reducing ability of melatonin and serotonin as trolox equivalent antioxidant activity (TEAC) was investigated. Melatonin and serotonin demonstrated 73.5 and 127.4 microg/mL trolox equivalent DMPD( radical+) scavenging activity at the concentration of 100 microg/mL. Also, at the same concentration, melatonin and serotonin showed 14.41 and 116.09 microg/mL trolox equivalent cupric ion (Cu(2+)) reducing ability. These results showed that melatonin and serotonin had marked DMPD(radical+) radical scavenging and cupric ions (Cu(2+)) reducing ability. Especially, serotonin had higher DMPD radical scavenging and cupric ions (Cu(2+)) reducing activity than melatonin because of its phenolic group.
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Citations
Cites
The Chemistry behind Antioxidant Capacity Assays
Huang, D., Ou, B., & Prior, R. L. (2005) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf030723c · Cited by 6,162
Cited by
Antioxidants and antioxidant methods: an updated overview
Gulcin, İ. (2020) · Archives of Toxicology · doi:10.1007/s00204-020-02689-3 · Cited by 2,205
Lactation improves pancreatic β cell mass and function through serotonin production
Moon, J. H., Kim, H., Kim, H., Park, J., Choi, W., Choi, W., Hong, H. J., Ro, H.-J., Jun, S., Choi, S. H., et al. (2020) · Science Translational Medicine · doi:10.1126/scitranslmed.aay0455 · Cited by 67
Phenolic Melatonin-Related Compounds: Their Role as Chemical Protectors against Oxidative Stress
Galano, A., Castañeda-Arriaga, R., Pérez-González, A., Tan, D.-X., & Reiter, R. (2016) · Molecules · doi:10.3390/molecules21111442 · Cited by 60
Seoane-Viaño, I., Gómez-Lado, N., Lázare-Iglesias, H., Rey-Bretal, D., Lamela-Gómez, I., Otero-Espinar, F. J., Blanco-Méndez, J., Antúnez-López, J. R., Pombo-Pasín, M., Aguiar, P., et al. (2019) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2019.118713 · Cited by 24
Metadata
- Authors
- Gülçin, I.
- Venue
- Journal of Enzyme Inhibition and Medicinal Chemistry
- Publisher
- Informa UK Limited
- Published
- 2008-01-01
- Volume
- 23
- Issue
- 6
- Pages
- 871-876
- ISSN
- 1475-6366 (ISSN-L)
- 1475-6374
- OpenAlex
- W2097142587
- Cited by
- 167
- References
- 1
- FWCI
- 2.89
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Gülçin, I. (2008). Measurement of antioxidant ability of melatonin and serotonin by the DMPD and CUPRAC methods as trolox equivalent. Journal of Enzyme Inhibition and Medicinal Chemistry. https://doi.org/10.1080/14756360701626223
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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