Cited by 12Curcumin's Biomedical ApplicationsMedicinal Plant ResearchCOVID-19 Clinical Research Studies

Antiinflammatory Activities of Curcumin and Spirulina: Focus on Their Role against COVID-19

Perna, Angelica, Hay, Eleonora, Sellitto, Carmine, Del Genio, Emiliano, De Falco, Maria, Guerra, Germano, De Luca, Antonio, De Blasiis, Paolo +1 more·2023·Journal of Dietary Supplements

Abstract

Nutraceuticals have for several years aroused the interest of researchers for their countless properties, including the management of viral infections. In the context of the COVID-19 pandemic, studies and research on the antiviral properties of nutraceuticals have greatly increased. More specifically, over the past two years, researchers have focused on analyzing the possible role of nutraceuticals in reducing the risk of SARS-CoV-2 infection or mitigating the symptoms of COVID-19. Among nutraceuticals, turmeric, extracted from the rhizome of the Curcuma Longa plant, and spirulina, commercial name of the cyanobacterium Arthrospira platensis, have assumed considerable importance in recent years. The purpose of this review is to collect, through a search of the most recent articles on Pubmed, the scientific evidence on the role of these two compounds in the fight against COVID-19. In the last two years many hypotheses, some confirmed by clinical and experimental studies, have been made on the possible use of turmeric against COVID-19, while on spirulina and its possible role against SARS-CoV-2 infection information is much less. The demonstrated antiviral properties of spirulina and the fact that these cyanobacteria may modulate or modify some mechanisms also involved in the onset of COVID-19, lead us to think that it may have the same importance as curcumin in fighting this disease and to speculate on the possible combined use of these two substances to obtain a synergistic effect.

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Crossref · 10.1080/19390211.2023.2173354

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  • Some health-protective properties of spirulina are reflected in systematic reviews and meta-analyses of randomized clinical trials (Table 2).

    “Some health-protective properties of spirulina are reflected in systematic reviews and meta-analyses of randomized clinical trials (Table 2).”

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Authors
Perna, A., Hay, E., Sellitto, C., Del Genio, E., De Falco, M., Guerra, G., De Luca, A., De Blasiis, P., & Lucariello, A.
Affiliations
  • University of Molise (IT)
  • University of Campania "Luigi Vanvitelli" (IT)
  • Department of Mental and Physical Health and Preventive Medicine, Section of Human Anatomy, University of Campania “Luigi Vanvitelli”, Naples, Italy
  • Department of Biology, University of Naples ‘‘Federico II’’, Naples, Italy
  • Parthenope University of Naples (IT)
Corresponding author
Perna, Angelica
Venue
Journal of Dietary Supplements
Published
2023-02-02
Volume
20
Issue
2
Pages
372-389
ISSN
  • 1939-0211 (ISSN-L)
  • 1939-022X
OpenAlex
W4318926425
Cited by
12
References
88
Citations by year
2026: 3 · 2025: 2 · 2024: 5 · 2023: 2
FWCI
0.23
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Dietary Supplements (publishedVersion)
  • PubMed (publishedVersion)
  • CINECA IRIS Institutional Research Information System (University of Basilicata) (submittedVersion)
  • Archivio Istituzionale della Ricerca - Università degli Studi della Campania "Luigi Vanvitelli" (submittedVersion)
  • Archivio Istituzionale della Ricerca - Università degli Studi del Molise (submittedVersion)
  • CINECA IRIS Institutial research information system (Parthenope University of Naples) (submittedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Curcumin's Biomedical Applications
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
  • Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
Keywords
curcumin, Spirulina, Spirulina platensis, COVID-19 pandemic, SARS-CoV-2, nutraceuticals, anti-inflammatory activity, antiviral activity, turmeric, synergistic combination, viral infection prevention
MeSH terms
COVID-19, SARS-CoV-2, Anti-Inflammatory Agents, Antiviral Agents, Curcumin, Humans, Spirulina, Pandemics

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