Intestinal phages interact with bacteria and are involved in human diseases
Open accessAbstract
Phages are the most abundant and diverse biological entities on Earth and exert specific effects on bacterial hosts. The coexistence of phages and bacteria in the intestinal tract is dynamic and interdependent. Phages are involved in maintaining the stability and composition of the bacterial community, and an imbalance in phages and bacteria in the intestinal tract can cause diseases. This review elucidates interactions between phages and bacteria in the human intestinal tract and their roles in the pathogenesis and treatment of diseases. Understanding the relationship among phages, bacteria and host diseases is conducive to promoting the application of phages in the treatment of human diseases.List of abbreviations EMBL-EBI The European Bioinformatics Institute; E. coli Escherichia coli; E. faecalis Enterobacter faecalis; B. fragilis Bacteroides fragilis; B. vulgatus Bacteroides vulgatus; SaPIs Staphylococcus aureus pathogenicity islands; ARGs Antibiotic resistance genes; STEC Shiga toxigenic E. coli; Stx Shiga toxin; BLAST Basic Local Alignment Search Tool; TSST-1 Toxic shock toxin 1; RBPs Receptor-binding proteins; LPS lipopolysaccharide; OMVs Outer membrane vesicles; PT Phosphorothioate; BREX Bacteriophage exclusion; OCR Overcome classical restriction; Pgl Phage growth limitation; DISARM Defense island system associated with restrictionmodification; R-M system Restriction-modification system; BREX system Bacteriophage exclusion system; CRISPR Clustered regularly interspaced short palindromic repeats; Cas CRISPR-associated; PAMs Prospacer adjacent motifs; crRNA CRISPR RNA; SIE; OMPs; Superinfection exclusion; Outer membrane proteins; Abi Abortive infection; TA Toxin-antitoxin; TLR Toll-like receptor; APCs Antigen-presenting cells; DSS Dextran sulfate sodium; IELs Intraepithelial lymphocytes; FMT Fecal microbiota transfer; IFN-γ Interferon-gamma; IBD Inflammatory bowel disease; AgNPs Silver nanoparticles; MDSC Myeloid-derived suppressor cell; CRC Colorectal cancer; VLPs Virus-like particles; TMP Tape measure protein; PSMB4 Proteasome subunit beta type-4; ALD Alcohol-related liver disease; GVHD Graft-versus-host disease; ROS Reactive oxygen species; RA Rheumatoid arthritis; CCP Cyclic citrullinated protein; AMGs Accessory metabolic genes; T1DM Type 1 diabetes mellitus; T2DM Type 2 diabetes mellitus; SCFAs Short-chain fatty acids; GLP-1 Glucagon-like peptide-1; A. baumannii Acinetobacter baumannii; CpG Deoxycytidylinate-phosphodeoxyguanosine; PEG Polyethylene glycol; MetS Metabolic syndrome; OprM Outer membrane porin M.
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Chronic neuroinflammation caused by immune disorders triggers the accumulation of misfolded proteins in nervous system cells and peripheral nerves, further leading to neuronal death.
“Chronic neuroinflammation caused by immune disorders triggers the accumulation of misfolded proteins in nervous system cells and peripheral nerves (76), further leading to neuronal death (77).”
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Cites
Diversity of the Human Intestinal Microbial Flora
Eckburg, P. B., Bik, E. M., Bernstein, C. N., Purdom, E., Dethlefsen, L., Sargent, M., Gill, S. R., Nelson, K. E., & Relman, D. A. (2005) · Science · doi:10.1126/science.1110591 · Cited by 7,913 · see citing works
A metagenome-wide association study of gut microbiota in type 2 diabetes
Qin, J., Li, Y., Cai, Z., Li, S., Zhu, J., Zhang, F., Liang, S., Zhang, W., Guan, Y., Shen, D., et al. (2012) · Nature · doi:10.1038/nature11450 · Cited by 6,762 · see citing works
Gut metagenome in European women with normal, impaired and diabetic glucose control
Karlsson, F. H., Tremaroli, V., Nookaew, I., Bergström, G., Behre, C. J., Fagerberg, B., Nielsen, J., & Bäckhed, F. (2013) · Nature · doi:10.1038/nature12198 · Cited by 3,115 · see citing works
Tolhurst, G., Heffron, H., Lam, Y. S., Parker, H. E., Habib, A. M., Diakogiannaki, E., Cameron, J., Grosse, J., Reimann, F., & Gribble, F. M. (2012) · Diabetes · doi:10.2337/db11-1019 · Cited by 2,404 · see citing works
<i>Fusobacterium nucleatum</i> infection is prevalent in human colorectal carcinoma
Castellarin, M., Warren, R. L., Freeman, J. D., Dreolini, L., Krzywinski, M., Strauss, J., Barnes, R., Watson, P., Allen-Vercoe, E., Moore, R. A., et al. (2012) · Genome Research · doi:10.1101/gr.126516.111 · Cited by 2,043 · see citing works
Lysogenic Conversion by a Filamentous Phage Encoding Cholera Toxin
Waldor, M. K., & Mekalanos, J. J. (1996) · Science · doi:10.1126/science.272.5270.1910 · Cited by 1,851 · see citing works
Disease-Specific Alterations in the Enteric Virome in Inflammatory Bowel Disease
Norman, J. M., Handley, S. A., Baldridge, M. T., Droit, L., Liu, C. Y., Keller, B. C., Kambal, A., Monaco, C. L., Zhao, G., Fleshner, P., et al. (2015) · Cell · doi:10.1016/j.cell.2015.01.002 · Cited by 1,285 · see citing works
Schooley, R. T., Biswas, B., Gill, J. J., Hernandez-Morales, A., Lancaster, J., Lessor, L., Barr, J. J., Reed, S. L., Rohwer, F., Benler, S., et al. (2017) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00954-17 · Cited by 1,254 · see citing works
Viruses in the faecal microbiota of monozygotic twins and their mothers
Reyes, A., Haynes, M. R., Hanson, N., Angly, F. E., Heath, A. C., Rohwer, F. L., & Gordon, J. I. (2010) · Nature · doi:10.1038/nature09199 · Cited by 1,198 · see citing works
Taur, Y., Jenq, R. R., Perales, M.-A., Littmann, E. R., Morjaria, S., Ling, L., No, D., Gobourne, A., Viale, A., Dahi, P. B., et al. (2014) · Blood · doi:10.1182/blood-2014-02-554725 · Cited by 885 · see citing works
Jault, P., Leclerc, T., Jennes, S., Pirnay, J., Que, Y., Resch, G., Rousseau, A., Ravat, F., Carsin, H., Floch, R. L., et al. (2018) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(18)30482-1 · Cited by 878 · see citing works
An expansion of rare lineage intestinal microbes characterizes rheumatoid arthritis
Chen, J., Wright, K., Davis, J. M., Jeraldo, P., Marietta, E. V., Murray, J., Nelson, H., Matteson, E. L., & Taneja, V. (2016) · Genome Medicine · doi:10.1186/s13073-016-0299-7 · Cited by 858 · see citing works
Cuevas-Ramos, G., Petit, C. R., Marcq, I., Boury, M., Oswald, E., & Nougayrède, J.-P. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1001261107 · Cited by 855 · see citing works
Bacteriophage targeting of gut bacterium attenuates alcoholic liver disease
Duan, Y., Llorente, C., Lang, S., Brandl, K., Chu, H., Jiang, L., White, R. C., Clarke, T. H., Nguyen, K., Torralba, M., et al. (2019) · Nature · doi:10.1038/s41586-019-1742-x · Cited by 851 · see citing works
Bacteriophage genes that inactivate the CRISPR/Cas bacterial immune system
Bondy-Denomy, J., Pawluk, A., Maxwell, K. L., & Davidson, A. R. (2012) · Nature · doi:10.1038/nature11723 · Cited by 818 · see citing works
Sequence-specific antimicrobials using efficiently delivered RNA-guided nucleases
Citorik, R. J., Mimee, M., & Lu, T. K. (2014) · Nature Biotechnology · doi:10.1038/nbt.3011 · Cited by 808 · see citing works
The Human Gut Virome Is Highly Diverse, Stable, and Individual Specific
Shkoporov, A. N., Clooney, A. G., Sutton, T. D. S., Ryan, F. J., Daly, K. M., Nolan, J. A., McDonnell, S. A., Khokhlova, E. V., Draper, L. A., Forde, A., et al. (2019) · Cell Host & Microbe · doi:10.1016/j.chom.2019.09.009 · Cited by 737 · see citing works
Williams, B. B., Van Benschoten, A. H., Cimermancic, P., Donia, M. S., Zimmermann, M., Taketani, M., Ishihara, A., Kashyap, P. C., Fraser, J. S., & Fischbach, M. A. (2014) · Cell Host & Microbe · doi:10.1016/j.chom.2014.09.001 · Cited by 732 · see citing works
Phage selection restores antibiotic sensitivity in MDR Pseudomonas aeruginosa
Chan, B. K., Sistrom, M., Wertz, J. E., Kortright, K. E., Narayan, D., & Turner, P. E. (2016) · Scientific Reports · doi:10.1038/srep26717 · Cited by 723 · see citing works
Lytic to temperate switching of viral communities
Knowles, B., Silveira, C. B., Bailey, B., Barott, K. L., Cantu, A., Güemes, A. G. C., Coutinho, F. H., Dinsdale, E. A., Felts, B., Furby, K. A., et al. (2016) · Nature · doi:10.1038/nature17193 · Cited by 707 · see citing works
Communication between viruses guides lysis–lysogeny decisions
Erez, Z., Steinberger-Levy, I., Voichek, M., Doron, S., Stokar-Avihail, A., Peleg, Y., Melamed, S., Leavitt, A., Savidor, A., Albeck, S., et al. (2017) · Nature · doi:10.1038/nature21049 · Cited by 653 · see citing works
The Bacteroides fragilis toxin gene is prevalent in the colon mucosa of colorectal cancer patients
Boleij, A., Hechenbleikner, E. M., Goodwin, A. C., Badani, R., Stein, E. M., Lazarev, M. G., Ellis, B., Carroll, K. C., Albesiano, E., Wick, E. C., et al. (2015) · Clinical Infectious Diseases · doi:10.1093/cid/ciu787 · Cited by 625 · see citing works
Contribution of bacterial outer membrane vesicles to innate bacterial defense
Manning, A. J., & Kuehn, M. J. (2011) · BMC Microbiology · doi:10.1186/1471-2180-11-258 · Cited by 623 · see citing works
O’Brien, A. D., Newland, J. W., Miller, S. F., Holmes, R. K., Smith, H. W., & Formal, S. B. (1984) · Science · doi:10.1126/science.6387911 · Cited by 617 · see citing works
Expansion of Bacteriophages Is Linked to Aggravated Intestinal Inflammation and Colitis
Gogokhia, L., Buhrke, K., Bell, R. S., Hoffman, B., Brown, D. G., Hanke‐Gogokhia, C., Ajami, N. J., Wong, M. C., Ghazaryan, A., Valentine, J. F., et al. (2019) · Cell Host & Microbe · doi:10.1016/j.chom.2019.01.008 · Cited by 613 · see citing works
Massive expansion of human gut bacteriophage diversity
Camarillo-Guerrero, L. F., Almeida, A., Rangel-Pineros, G., Finn, R. D., & Lawley, T. D. (2021) · Cell · doi:10.1016/j.cell.2021.01.029 · Cited by 594 · see citing works
Dynamic modulation of the gut microbiota and metabolome by bacteriophages in a mouse model
Hsu, B. B., Gibson, T. E., Yeliseyev, V., Liu, Q., Lyon, L., Bry, L., Silver, P. A., & Gerber, G. K. (2019) · Cell Host & Microbe · doi:10.1016/j.chom.2019.05.001 · Cited by 573 · see citing works
Fecal Microbiota Composition Differs Between Children With β-Cell Autoimmunity and Those Without
de Goffau, M. C., Luopajärvi, K., Knip, M., Ilonen, J., Ruohtula, T., Härkönen, T., Orivuori, L., Hakala, S., Welling, G. W., Harmsen, H. J. M., et al. (2012) · Diabetes · doi:10.2337/db12-0526 · Cited by 563 · see citing works
A DNA nanodevice-based vaccine for cancer immunotherapy
Liu, S., Jiang, Q., Zhao, X., Zhao, R., Wang, Y., Wang, Y., Liu, J., Shang, Y., Zhao, S., Wu, T., et al. (2020) · Nature Materials · doi:10.1038/s41563-020-0793-6 · Cited by 552 · see citing works
Sarker, S. A., Sultana, S., Reuteler, G., Moine, D., Descombes, P., Charton, F., Bourdin, G., McCallin, S. E., Ngom‐Bru, C., Neville, T., et al. (2016) · EBioMedicine · doi:10.1016/j.ebiom.2015.12.023 · Cited by 543 · see citing works
Antibiotic treatment expands the resistance reservoir and ecological network of the phage metagenome
Modi, S. R., Lee, H. H., Spina, C. S., & Collins, J. J. (2013) · Nature · doi:10.1038/nature12212 · Cited by 542 · see citing works
Manrique, P., Bolduc, B., Walk, S. T., John van der, O. O. S. T., de Vos, W. M., & Young, M. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1601060113 · Cited by 538 · see citing works
Prophages mediate defense against phage infection through diverse mechanisms
Bondy‐Denomy, J., Qian, J., Westra, E. R., Buckling, A. G. J., Guttman, D. S., Davidson, A. R., & Maxwell, K. L. (2016) · The ISME Journal · doi:10.1038/ismej.2016.79 · Cited by 507 · see citing works
Temperate and lytic bacteriophages programmed to sensitize and kill antibiotic-resistant bacteria
Yosef, I., Manor, M., Kiro, R., & Qimron, U. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1500107112 · Cited by 501 · see citing works
BREX is a novel phage resistance system widespread in microbial genomes
Goldfarb, T., Sberro, H., Weinstock, E., Cohen, O., Doron, S., Charpak‐Amikam, Y., Afik, S., Ofir, G., & Sorek, R. (2014) · The EMBO Journal · doi:10.15252/embj.201489455 · Cited by 501 · see citing works
A novel mechanism for the biogenesis of outer membrane vesicles in Gram-negative bacteria
Roier, S., Zingl, F. G., Çakar, F., Durakovic, S., Kohl, P., Eichmann, T. O., Klug, L., Gadermaier, B., Weinzerl, K., Prassl, R., et al. (2016) · Nature Communications · doi:10.1038/ncomms10515 · Cited by 500 · see citing works
Virus Population Dynamics and Acquired Virus Resistance in Natural Microbial Communities
Andersson, A. F., & Banfield, J. F. (2008) · Science · doi:10.1126/science.1157358 · Cited by 497 · see citing works
Roach, D. R., Leung, C. Y., Henry, M., Morello, E., Singh, D., Santo, J. P. D., Weitz, J. S., & Debarbieux, L. (2017) · Cell Host & Microbe · doi:10.1016/j.chom.2017.06.018 · Cited by 489 · see citing works
Zheng, D., Dong, X., Pan, P., Chen, K.-W., Fan, J., Cheng, S., & Zhang, X. (2019) · Nature Biomedical Engineering · doi:10.1038/s41551-019-0423-2 · Cited by 483 · see citing works
Molecular and Evolutionary Determinants of Bacteriophage Host Range
de Jonge, P. A., Nóbrega, F. L., Brouns, S. J. J., & Dutilh, B. E. (2018) · Trends in Microbiology · doi:10.1016/j.tim.2018.08.006 · Cited by 481 · see citing works
Safety of bacteriophage therapy in severe Staphylococcus aureus infection
Fabijan, A. P., Lin, R. C. Y., Ho, J., Maddocks, S., Zakour, N. L. B., Iredell, J. R., Westmead Bacteriophage Therapy Team, Khalid, A., Venturini, C., Chard, R., et al. (2020) · Nature Microbiology · doi:10.1038/s41564-019-0634-z · Cited by 474 · see citing works
Sato, J., Kanazawa, A., Ikeda, F., Yoshihara, T., Goto, H., Abe, H., Komiya, K., Kawaguchi, M., Shimizu, T., Ogihara, T., et al. (2014) · Diabetes Care · doi:10.2337/dc13-2817 · Cited by 438 · see citing works
Phages rarely encode antibiotic resistance genes: a cautionary tale for virome analyses
Enault, F., Briet, A., Bouteille, L., Roux, S., Sullivan, M. B., & Petit, M. (2016) · The ISME Journal · doi:10.1038/ismej.2016.90 · Cited by 432 · see citing works
Engineering Modular Viral Scaffolds for Targeted Bacterial Population Editing
Ando, H., Lemire, S., Pires, D. P., & Lu, T. K. (2015) · Cell Systems · doi:10.1016/j.cels.2015.08.013 · Cited by 429 · see citing works
Application of a Neutral Community Model To Assess Structuring of the Human Lung Microbiome
Venkataraman, A., Bassis, C. M., Beck, J. M., Young, V. B., Curtis, J. L., Huffnagle, G. B., & Schmidt, T. M. (2015) · mBio · doi:10.1128/mbio.02284-14 · Cited by 428 · see citing works
Lindsay, J. A., Ruzin, A. V., Ross, H. F., Kurepina, N., & Novick, R. P. (1998) · Molecular Microbiology · doi:10.1046/j.1365-2958.1998.00947.x · Cited by 414 · see citing works
Landscapes of bacterial and metabolic signatures and their interaction in major depressive disorders
Yang, J., Zheng, P., Li, Y., Wu, J., Tan, X., Zhou, J., Sun, Z., Chen, X., Zhang, G., Zhang, H., et al. (2020) · Science Advances · doi:10.1126/sciadv.aba8555 · Cited by 408 · see citing works
Cross-reactivity between tumor MHC class I–restricted antigens and an enterococcal bacteriophage
Fluckiger, A., Daillère, R., Sassi, M., Sixt, B. S., Liu, P., Loos, F., Richard, C., Rabu, C., Alou, M. T., Goubet, A.-G., et al. (2020) · Science · doi:10.1126/science.aax0701 · Cited by 396 · see citing works
Alterations in Enteric Virome Are Associated With Colorectal Cancer and Survival Outcomes
Nakatsu, G., Zhou, H., Wu, W. K. K., Wong, S. H., Coker, O. O., Dai, Z., Li, X., Szeto, C.-H., Sugimura, N., Lam, T. Y.-T., et al. (2018) · Gastroenterology · doi:10.1053/j.gastro.2018.04.018 · Cited by 386 · see citing works
Bacteriophage Transcytosis Provides a Mechanism To Cross Epithelial Cell Layers
Nguyen, S., Baker, K., Padman, B. S., Patwa, R. R., Dunstan, R. A., Weston, T. A., Schlosser, K., Bailey, B., Lithgow, T. J., Lazarou, M., et al. (2017) · mBio · doi:10.1128/mbio.01874-17 · Cited by 383 · see citing works
A bacteriophage encodes its own CRISPR/Cas adaptive response to evade host innate immunity
Seed, K. D., Lazinski, D. W., Calderwood, S. B., & Camilli, A. (2013) · Nature · doi:10.1038/nature11927 · Cited by 375 · see citing works
Kakihana, K., Fujioka, Y., Suda, W., Najima, Y., Kuwata, G., Sasajima, S., Mimura, I., Morita, H., Sugiyama, D., Nishikawa, H., et al. (2016) · Blood · doi:10.1182/blood-2016-05-717652 · Cited by 367 · see citing works
Zuo, T., Wong, S. H., Lam, K., Lui, R. N.-S., Cheung, K., Tang, W., Ching, J. Y. L., Chan, P. K. S., Chan, M. C. W., Wu, J. C., et al. (2017) · Gut · doi:10.1136/gutjnl-2017-313952 · Cited by 344 · see citing works
DISARM is a widespread bacterial defence system with broad anti-phage activities
Ofir, G., Melamed, S., Sberro, H., Mukamel, Z., Silverman, S., Yaakov, G., Doron, S., & Sorek, R. (2017) · Nature Microbiology · doi:10.1038/s41564-017-0051-0 · Cited by 333 · see citing works
Statistical structure of host–phage interactions
Flores, C. O., Meyer, J. R., Valverde, S., Farr, L., & Weitz, J. S. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1101595108 · Cited by 331 · see citing works
Phage-Mediated Intergeneric Transfer of Toxin Genes
Chen, J. Y.-S., & Novick, R. P. (2009) · Science · doi:10.1126/science.1164783 · Cited by 314 · see citing works
Diagnostic potential and interactive dynamics of the colorectal cancer virome
Hannigan, G. D., Duhaime, M. B., Ruffin, M. T., Koumpouras, C. C., & Schloss, P. D. (2018) · mBio · doi:10.1128/mbio.02248-18 · Cited by 298 · see citing works
Dong, X., Pan, P., Zheng, D., Bao, P., Zeng, X., & Zhang, X. (2020) · Science Advances · doi:10.1126/sciadv.aba1590 · Cited by 282 · see citing works
Intestinal virome changes precede autoimmunity in type I diabetes-susceptible children
Zhao, G., Vatanen, T., Droit, L., Park, A., Kostic, A. D., Poon, T. W., Vlamakis, H. C., Siljander, H., Härkönen, T., Hämäläinen, A.-M., et al. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1706359114 · Cited by 280 · see citing works
Standardized bacteriophage purification for personalized phage therapy
Luong, T., Salabarria, A.-C., Edwards, R. A., & Roach, D. R. (2020) · Nature Protocols · doi:10.1038/s41596-020-0346-0 · Cited by 274 · see citing works
The stepwise assembly of the neonatal virome is modulated by breastfeeding
Liang, G., Zhao, C., Zhang, H., Mattei, L. M., Sherrill-Mix, S. A., Bittinger, K. L., Kessler, L. R., Wu, G. D., Baldassano, R. N., DeRusso, P. A., et al. (2020) · Nature · doi:10.1038/s41586-020-2192-1 · Cited by 272 · see citing works
Everard, A., & Cani, P. D. (2014) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-014-9288-6 · Cited by 266 · see citing works
Faecal virome transplantation decreases symptoms of type 2 diabetes and obesity in a murine model
Rasmussen, T. S., Mentzel, C. M. J., Kot, W., Castro-Mejía, J. L., Zuffa, S., Swann, J. R., Hansen, L. H., Vogensen, F. K., Hansen, A. K., & Nielsen, D. S. (2020) · Gut · doi:10.1136/gutjnl-2019-320005 · Cited by 249 · see citing works
Global phylogeography and ancient evolution of the widespread human gut virus crAssphage
Edwards, R. A., Vega, A. A., Norman, H. M., Ohaeri, M. C., Levi, K., Dinsdale, E. A., Cinek, O., Aziz, R. K., McNair, K. A., Barr, J. J., et al. (2019) · Nature Microbiology · doi:10.1038/s41564-019-0494-6 · Cited by 247 · see citing works
Role of the Gut Microbiome in Modulating Arthritis Progression in Mice
Liu, X., Zeng, B., Zhang, J., Li, W., Mou, F., Wang, H., Zou, Q., Zhong, B., Wu, L., Wei, H., et al. (2016) · Scientific Reports · doi:10.1038/srep30594 · Cited by 245 · see citing works
A cocktail of three virulent bacteriophages prevents Vibrio cholerae infection in animal models
Yen, M., Cairns, L. S., & Camilli, A. (2017) · Nature Communications · doi:10.1038/ncomms14187 · Cited by 239 · see citing works
Intestinal microbiota in health and disease
Kåhrström, C. T., Pariente, N., & Weiss, U. K. (2016) · Nature · doi:10.1038/535047a · Cited by 231 · see citing works
In Vivo Targeting of Clostridioides difficile Using Phage-Delivered CRISPR-Cas3 Antimicrobials
Selle, K., Fletcher, J. R., Tuson, H. H., Schmitt, D. S., McMillan, L. J., Vridhambal, G. S., Rivera, A. J., Montgomery, S. A., Fortier, L., Barrangou, R., et al. (2020) · mBio · doi:10.1128/mbio.00019-20 · Cited by 228 · see citing works
Molecular genetics of SaPI1 – a mobile pathogenicity island in Staphylococcus aureus
Ruzin, A. V., Lindsay, J. A., & Novick, R. P. (2001) · Molecular Microbiology · doi:10.1046/j.1365-2958.2001.02488.x · Cited by 212 · see citing works
Escherichia coli K1's Capsule Is a Barrier to Bacteriophage T7
Scholl, D., Adhya, S. L., & Merril, C. R. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.8.4872-4874.2005 · Cited by 208 · see citing works
A human gut phage catalog correlates the gut phageome with type 2 diabetes
Ma, Y., You, X., Mai, G., Tokuyasu, T. A., & Liu, C. (2018) · Microbiome · doi:10.1186/s40168-018-0410-y · Cited by 204 · see citing works
Golob, J. L., Pergam, S. A., Srinivasan, S., Fiedler, T. L., Liu, C., Garcia, K., Mielcarek, M., Ko, D., Aker, S., Marquis, S., et al. (2017) · Clinical Infectious Diseases · doi:10.1093/cid/cix699 · Cited by 201 · see citing works
Kovacs, E. W., Hooker, J. M., Romanini, D. W., Holder, P. G., Berry, K. E., & Francis, M. B. (2007) · Bioconjugate Chemistry · doi:10.1021/bc070006e · Cited by 196 · see citing works
Lourenço, M., Chaffringeon, L., Lamy-Besnier, Q., Pédron, T., Campagne, P., Eberl, C., Berard, M., Stecher, B., Debarbieux, L., & Sordi, L. D. (2020) · Cell Host & Microbe · doi:10.1016/j.chom.2020.06.002 · Cited by 195 · see citing works
Vibrio cholerae Outer Membrane Vesicles Inhibit Bacteriophage Infection
Robles, T. R., Dillard, R. S., Cairns, L. S., Silva-Valenzuela, C. A., Housman, M., Ali, A., Wright, E. R., & Camilli, A. (2018) · Journal of Bacteriology · doi:10.1128/jb.00792-17 · Cited by 194 · see citing works
Jubair, W. K., Hendrickson, J. D., Severs, E., Schulz, H. M., Adhikari, S., Ir, D., Pagan, J. D., Anthony, R. M., Robertson, C. E., Frank, D. N., et al. (2018) · Arthritis & Rheumatology · doi:10.1002/art.40490 · Cited by 190 · see citing works
Malone, L. M., Warring, S. L., Jackson, S. A., Warnecke, C., Gardner, P. P., Gumy, L. F., & Fineran, P. C. (2019) · Nature Microbiology · doi:10.1038/s41564-019-0612-5 · Cited by 189 · see citing works
Gill, J. J., Pacan, J. C., Carson, M. E., Leslie, K. E., Griffiths, M. W., & Sabour, P. M. (2006) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01630-05 · Cited by 184 · see citing works
Manohar, P., Tamhankar, A. J., Lundborg, C. S., & Nachimuthu, R. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.00574 · Cited by 179 · see citing works
Phage‐Enabled Nanomedicine: From Probes to Therapeutics in Precision Medicine
Sunderland, K. S., Yang, M., & Mao, C. (2016) · Angewandte Chemie International Edition · doi:10.1002/anie.201606181 · Cited by 171 · see citing works
Acquisition of Phage Sensitivity by Bacteria through Exchange of Phage Receptors
Tzipilevich, E., Habusha, M., & Ben‐Yehuda, S. (2016) · Cell · doi:10.1016/j.cell.2016.12.003 · Cited by 169 · see citing works
The Rex system of bacteriophage lambda: tolerance and altruistic cell death.Preprint
Parma, D. H., Snyder, M., Sobolevski, S., Nawroz, M., Brody, E. N., & Gold, L. M. (1992) · Genes & Development · doi:10.1101/gad.6.3.497 · Cited by 165 · see citing works
The Battle Within: Interactions of Bacteriophages and Bacteria in the Gastrointestinal Tract
Sordi, L. D., Lourenço, M., & Debarbieux, L. (2019) · Cell Host & Microbe · doi:10.1016/j.chom.2019.01.018 · Cited by 163 · see citing works
Seed, K. D., Faruque, S. M., Mekalanos, J. J., Calderwood, S. B., Qadri, F., & Camilli, A. (2012) · PLoS Pathogens · doi:10.1371/journal.ppat.1002917 · Cited by 159 · see citing works
Pseudomonas aeruginosa defends against phages through type IV pilus glycosylation
Harvey, H., Bondy‐Denomy, J., Marquis, H., Sztanko, K. M., Davidson, A. R., & Burrows, L. L. (2017) · Nature Microbiology · doi:10.1038/s41564-017-0061-y · Cited by 154 · see citing works
Intestinal Virome in Patients With Alcoholic Hepatitis
Jiang, L., Lang, S., Duan, Y., Zhang, X., Gao, B., Chopyk, J., Schwanemann, L. K., Cots, M. V., Bataller, R. A., Bosques‐Padilla, F., et al. (2020) · Hepatology · doi:10.1002/hep.31459 · Cited by 149 · see citing works
Górski, A., Dąbrowska, K., Międzybrodzki, R., Weber‐Dąbrowska, B., Łusiak-Szelachowska, M., Jończyk‐Matysiak, E., & Borysowski, J. (2017) · Future Microbiology · doi:10.2217/fmb-2017-0049 · Cited by 146 · see citing works
Lehti, T. A., Pajunen, M. I., Skog, M. S., & Finne, J. (2017) · Nature Communications · doi:10.1038/s41467-017-02057-3 · Cited by 142 · see citing works
Superinfection exclusion by T-even-type coliphages
Lu, M., & Henning, U. (1994) · Trends in Microbiology · doi:10.1016/0966-842x(94)90601-7 · Cited by 135 · see citing works
Connil, N., Breton, Y. S. L., Dousset, X., Auffray, Y., Rincé, A., & Prévost, H. (2002) · Applied and Environmental Microbiology · doi:10.1128/aem.68.7.3537-3544.2002 · Cited by 134 · see citing works
Multi-species host range of staphylococcal phages isolated from wastewater
Göller, P. C., Elsener, T. A., Lorgé, D., Radulovic, N., Bernardi, V., Naumann, A., Amri, N., Khatchatourova, E., Coutinho, F. H., Loessner, M. J., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-27037-6 · Cited by 132 · see citing works
Guegler, C. K., & Laub, M. T. (2021) · Molecular Cell · doi:10.1016/j.molcel.2021.03.027 · Cited by 131 · see citing works
Xiong, X., Wu, G., Wei, Y., Liu, L., Zhang, Y., Su, R., Jiang, X., Li, M., Gao, H., Tian, X., et al. (2020) · Nature Microbiology · doi:10.1038/s41564-020-0700-6 · Cited by 130 · see citing works
Superinfection exclusion by P22 prophage in lysogens of Salmonella typhimurium
Susskind, M. M., Botstein, D., & Wright, A. (1974) · Virology · doi:10.1016/0042-6822(74)90398-5 · Cited by 122 · see citing works
Bacteriophages as potential new mammalian pathogens
Tetz, G. V., Ruggles, K. V., Zhou, H., Heguy, A., Tsirigos, A., & Tetz, V. (2017) · Scientific Reports · doi:10.1038/s41598-017-07278-6 · Cited by 120 · see citing works
Temperate Phage-Antibiotic Synergy Eradicates Bacteria Through Depletion of Lysogens
Al-Anany, A. M., Fatima, R., & Hynes, A. P. (2020) · Cell Reports · doi:10.1016/j.celrep.2021.109172 · Cited by 115 · see citing works
Co-evolution with lytic phage selects for the mucoid phenotype of Pseudomonas fluorescens SBW25
Scanlan, P. D., & Buckling, A. G. J. (2011) · The ISME Journal · doi:10.1038/ismej.2011.174 · Cited by 114 · see citing works
Taha, O. A., Connerton, P. L., Connerton, I. F., & El‐Shibiny, A. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.02127 · Cited by 108 · see citing works
Cieplak, T., Soffer, N., Sulakvelidze, A., & Nielsen, D. S. (2018) · Gut Microbes · doi:10.1080/19490976.2018.1447291 · Cited by 107 · see citing works
Phage T7 DNA mimic protein Ocr is a potent inhibitor of BREX defence
Isaev, A. B., Drobiazko, A., Sierro, N., Gordeeva, J., Yosef, I., Qimron, U., Ivanov, N. V., & Severinov, K. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa290 · Cited by 106 · see citing works
Commensal viruses maintain intestinal intraepithelial lymphocytes via noncanonical RIG-I signaling
Liu, L., Gong, T., Tao, W., Lin, B., Li, C., Zheng, X., Zhu, S., Jiang, W., & Zhou, R. (2019) · Nature Immunology · doi:10.1038/s41590-019-0513-z · Cited by 105 · see citing works
Evidence that TraT interacts with OmpA of Escherichia coli
Riede, I., & Eschbach, M.-L. (1986) · FEBS Letters · doi:10.1016/0014-5793(86)80905-x · Cited by 101 · see citing works
Adiliaghdam, F., Amatullah, H., Digumarthi, S., Saunders, T. L., Rahman, R., Wong, L., Sadreyev, R. I., Droit, L., Paquette, J., Goyette, P., et al. (2022) · Science immunology · doi:10.1126/sciimmunol.abn6660 · Cited by 99 · see citing works
T4 Phage Tail Adhesin Gp12 Counteracts LPS-Induced Inflammation In Vivo
Miernikiewicz, P., Kłopot, A., Soluch, R., Szkuta, P. T., Kęska, W., Hodyra‐Stefaniak, K., Konopka, A., Nowak, M., Lecion, D., Kaźmierczak, Z. M., et al. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.01112 · Cited by 98 · see citing works
Mangalea, M. R., Páez-Espino, D., Kieft, K., Chatterjee, A., Chriswell, M. E., Seifert, J. A., Feser, M. L., Demoruelle, M. K., Sakatos, A., Anantharaman, K., et al. (2021) · Cell Host & Microbe · doi:10.1016/j.chom.2021.03.020 · Cited by 98 · see citing works
Quiles‐Puchalt, N., Carpena, N., Alonso, J. C., Novick, R. P., Marina, A., & Penadés, J. R. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1320538111 · Cited by 94 · see citing works
Nakao, R., Senpuku, H., & Watanabe, H. (2006) · Infection and Immunity · doi:10.1128/iai.00261-06 · Cited by 93 · see citing works
Międzybrodzki, R., Świtała-Jeleń, K., Fortuna, W., Weber‐Dąbrowska, B., Przerwa, A., Łusiak-Szelachowska, M., Dąbrowska, K., Kurzępa, A., Boratyński, J., Syper, D., et al. (2007) · Virus Research · doi:10.1016/j.virusres.2007.09.013 · Cited by 92 · see citing works
Effects of bacteriophages on free radical production and phagocytic functions
Przerwa, A., Zimecki, M., Świtała-Jeleń, K., Dąbrowska, K., Krawczyk, E., Łuczak, M., Weber‐Dąbrowska, B., Syper, D., Międzybrodzki, R., & Górski, A. (2006) · Medical Microbiology and Immunology · doi:10.1007/s00430-006-0011-4 · Cited by 92 · see citing works
“I will survive”: A tale of bacteriophage-bacteria coevolution in the gut
Sordi, L. D., Lourenço, M., & Debarbieux, L. (2018) · Gut Microbes · doi:10.1080/19490976.2018.1474322 · Cited by 89 · see citing works
Ngweniform, P., Abbineni, G., Cao, B., & Mao, C. (2009) · Small · doi:10.1002/smll.200801902 · Cited by 82 · see citing works
Bacteriophages as New Human Viral Pathogens
Tetz, G. V., & Tetz, V. (2018) · Microorganisms · doi:10.3390/microorganisms6020054 · Cited by 82 · see citing works
Destabilizing mutations encode nongenetic variation that drives evolutionary innovation
Petrie, K. L., Palmer, N. D., Johnson, D. T., Medina, S. J., Yan, S. J., Li, V. C., Burmeister, A. R., & Meyer, J. R. (2018) · Science · doi:10.1126/science.aar1954 · Cited by 79 · see citing works
Phage-induced diversification improves host evolvability
Williams, H. T. P. (2013) · BMC Evolutionary Biology · doi:10.1186/1471-2148-13-17 · Cited by 77 · see citing works
Tetz, G. V., Brown, S. M., Hao, Y., & Tetz, V. (2019) · Scientific Reports · doi:10.1038/s41598-019-46087-x · Cited by 77 · see citing works
Niu, Y. D., McAllister, T. A., Nash, J. J., Kropinski, A. M., & Stanford, K. (2014) · PLoS ONE · doi:10.1371/journal.pone.0100426 · Cited by 71 · see citing works
Mancini, N., Greco, R., Pasciuta, R., Barbanti, M. C., Pini, G. M., Morrow, O., Morelli, M., Vago, L., Clementi, N., Giglio, F., et al. (2017) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofx215 · Cited by 71 · see citing works
The agricultural antibiotic carbadox induces phage-mediated gene transfer in Salmonella
Bearson, B. L., Allen, H. K., Brunelle, B. W., Lee, I. S., Casjens, S., & Stanton, T. B. (2014) · Frontiers in Microbiology · doi:10.3389/fmicb.2014.00052 · Cited by 67 · see citing works
Molecular keys of the tropism of integration of the cholera toxin phage
Das, B., Bischerour, J., Val, M., & Barre, F. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0910212107 · Cited by 63 · see citing works
Meinel, D. M., Margos, G., Konrad, R., Krebs, S., Blum, H., & Sing, A. (2014) · Genome Medicine · doi:10.1186/s13073-014-0113-3 · Cited by 57 · see citing works
Hess, K. L., Andorko, J. I., Tostanoski, L. H., & Jewell, C. M. (2016) · Biomaterials · doi:10.1016/j.biomaterials.2016.11.052 · Cited by 57 · see citing works
Biased gene transfer mimics patterns created through shared ancestry
Andam, C. P., Williams, D. F., & Gogarten, J. P. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1001418107 · Cited by 53 · see citing works
TLR4/MD2 specific peptides stalled in vivo LPS-induced immune exacerbation
Park, S.-H., Shin, H., Shah, M., Cho, H.-Y., Anwar, M. A., Achek, A., Kwon, H., Byugsung, L., Yoo, T. H., & Choi, S. (2017) · Biomaterials · doi:10.1016/j.biomaterials.2017.02.023 · Cited by 53 · see citing works
Liu, Y., Dai, L., Dong, J., Chen, C., Zhu, J., Rao, V. B., & Pan, T. (2020) · Journal of Virology · doi:10.1128/jvi.01630-20 · Cited by 53 · see citing works
Meaden, S., Biswas, A., Arkhipova, K., Morales, S. E., Dutilh, B. E., Westra, E. R., & Fineran, P. C. (2021) · Current Biology · doi:10.1016/j.cub.2021.10.038 · Cited by 53 · see citing works
Doore, S. M., Schrad, J. R., Dean, W. F., Dover, J. A., & Parent, K. N. (2018) · Journal of Virology · doi:10.1128/jvi.02117-17 · Cited by 50 · see citing works
Enteric Phageome Alterations in Patients With Type 2 Diabetes
Chen, Q., Ma, X., Li, C., Shen, Y., Zhu, W., Zhang, Y., Guo, X., Zhou, J., & Liu, C. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2020.575084 · Cited by 49 · see citing works
Manrique, P., Zhu, Y., John van der, O. O. S. T., Herrema, H., Nieuwdorp, M., de Vos, W. M., & Young, M. (2021) · Gut Microbes · doi:10.1080/19490976.2021.1897217 · Cited by 49 · see citing works
The In-Feed Antibiotic Carbadox Induces Phage Gene Transcription in the Swine Gut Microbiome
Johnson, T. A., Looft, T. P., Severin, A. J., Bayles, D. O., Nasko, D. J., Wommack, K. E., Howe, A., & Allen, H. K. (2017) · mBio · doi:10.1128/mbio.00709-17 · Cited by 48 · see citing works
Murgas, P., Bustamante, N., Araya, N., Cruz, S. R., Durán-Jara, E., Gaete, D., Oyarce, C., López, E., Herrada, A. A., Ferreira, N., et al. (2017) · Cancer Immunology Immunotherapy · doi:10.1007/s00262-017-2076-x · Cited by 40 · see citing works
Myoviridae phage PDX kills enteroaggregative Escherichia coli without human microbiome dysbiosis
Cepko, L. C. S., Garling, E. E., Dinsdale, M. J., Scott, W. P., Bandy, L., Nice, T. J., Faber-Hammond, J. J., & Mellies, J. L. (2020) · Journal of Medical Microbiology · doi:10.1099/jmm.0.001162 · Cited by 39 · see citing works
A hyperpromiscuous antitoxin protein domain for the neutralization of diverse toxin domains
Kurata, T., Saha, C. K., Buttress, J. A., Mets, T., Brodiazhenko, T., Turnbull, K. J., Awoyomi, O. F., Oliveira, S. R. A., Jimmy, S., Ernits, K., et al. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2102212119 · Cited by 38 · see citing works
Ohshima, Y., Schumacher-Perdreau, F., Peters, G., & Pulverer, G. (1988) · Medical Microbiology and Immunology · doi:10.1007/bf00211222 · Cited by 37 · see citing works
Immune–bacteriophage interactions in inflammatory bowel diseases
Gogokhia, L., & Round, J. L. (2021) · Current Opinion in Virology · doi:10.1016/j.coviro.2021.04.010 · Cited by 34 · see citing works
Liang, Y., Ma, S., Zhang, Y., Wang, Y., Cheng, Q., Wu, Y., Jin, Y., Zheng, D., Wu, D., & Liu, H. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1203428 · Cited by 32 · see citing works
Bleriot, I., Blasco, L., Pacios, O., Fernández-García, L., Ambroa, A., López, M. C., Ortiz-Cartagena, C., Fernández-Cuenca, F., Oteo, J., Pascual, Á., et al. (2022) · Scientific Reports · doi:10.1038/s41598-022-08111-5 · Cited by 30 · see citing works
Lambda display phage as a mucosal vaccine delivery vehicle for peptide antigens
González‐Cano, P., Gamage, L. N. A., Marciniuk, K., Hayes, C., Napper, S., Hayes, S., & Griebel, P. J. (2017) · Vaccine · doi:10.1016/j.vaccine.2017.11.010 · Cited by 28 · see citing works
Prevalence of phase variable epigenetic invertons among host-associated bacteria
Huang, X., Wang, J., Li, J., Liu, Y., Liu, X., Li, Z., Kurniyati, K., Deng, Y., Wang, G., Ralph, J. D., et al. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa907 · Cited by 28 · see citing works
Fong, K., Mu, K., Emond-Rhéault, J.-G., Lévesque, R. C., Kitts, D. D., DELAQUIS, P. J., Goodridge, L. D., & Wang, S. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21051883 · Cited by 24 · see citing works
Preparation of a Nanobody Specific to Dectin 1 and Its Anti-inflammatory Effects on Fungal Keratitis
Liu, X., Sui, J., Li, C., Peng, X., Wang, Q., Jiang, N., Xu, Q., Wang, L., Lin, J., & Zhao, G. (2022) · International Journal of Nanomedicine · doi:10.2147/ijn.s338974 · Cited by 24 · see citing works
Koudelka, G. B., Arnold, J. W., & Chakraborty, D. (2018) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2018.07.001 · Cited by 23 · see citing works
Biological responses to M13 bacteriophage modified titanium surfaces in vitro
Sun, Y., Li, Y., Wu, B., Wang, J., Lu, X., Qu, S., Weng, J., & Feng, B. (2017) · Acta Biomaterialia · doi:10.1016/j.actbio.2017.06.019 · Cited by 19 · see citing works
Chattopadhyay, G., Bhasin, M., Ahmed, S., Gosain, T. P., Ganesan, S., Das, S., Thakur, C., Chandra, N. R., Singh, R., & Varadarajan, R. (2022) · Journal of Bacteriology · doi:10.1128/jb.00058-22 · Cited by 19 · see citing works
Characterization of hyaluronic acid specific hyaluronate lyase (HylP) from Streptococcus pyogenes
Singh, S. K., Malhotra, S., & Akhtar, M. S. (2014) · Biochimie · doi:10.1016/j.biochi.2014.03.012 · Cited by 18 · see citing works
Gomes-Neto, J. F., Sartorius, R., Canto, F. B., Almeida, T. S., Dias, A. A., Barbosa, C. H., Melo, G. A., Oliveira, A. C., de Aguiar, P. H. N., Machado, C. R., et al. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.01173 · Cited by 18 · see citing works
Pinto, A. M., Faustino, A., Pastrana, L. M., Bañobre‐López, M., & Sillankorva, S. (2021) · Antibiotics · doi:10.3390/antibiotics10070877 · Cited by 16 · see citing works
Visualizing the phage T4 activated transcription complex of DNA and E. coli RNA polymerase
James, T. D., Cardozo, T. J., Abell, L. E., Hsieh, M., Jenkins, L. M. M., Jha, S. S., & Hinton, D. M. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkw656 · Cited by 15 · see citing works
The Future of Virology is Synthetic
White, R. A., III (2021) · mSystems · doi:10.1128/msystems.00770-21 · Cited by 15 · see citing works
Cor interacts with outer membrane proteins to exclude FhuA-dependent phages
Arguijo-Hernández, E. S., Hernández‐Sánchez, J., Briones-Peña, S. J., Oviedo, N., Mendoza‐Hernández, G., Guarneros, G., & Kameyama, L. (2018) · Archives of Virology · doi:10.1007/s00705-018-3954-z · Cited by 13 · see citing works
Jalasvuori, M., & Koskinen, K. (2018) · Virology · doi:10.1016/j.virol.2018.02.014 · Cited by 12 · see citing works
Manipulating the gut microbiota to combat alcoholic hepatitis
Ray, K. (2019) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-019-0246-3 · Cited by 8 · see citing works
Bacterial toxin linked to severe alcoholic liver disease
Frederick, E. (2019) · Science · doi:10.1126/science.366.6467.784 · Cited by 4 · see citing works
Alattas, H., Wong, S. L., & Slavcev, R. A. (2020) · Genetics · doi:10.1534/genetics.120.303643 · Cited by 3 · see citing works
A phingerprint for rheumatoid arthritis development?
Sinha, A., & Maurice, C. F. (2021) · Cell Host & Microbe · doi:10.1016/j.chom.2021.04.009 · Cited by 1 · see citing works
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Zhang, K., Ma, Y., Luo, Y., Song, Y., Xiong, G., Ma, Y., Sun, X., & Kan, C. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1253506 · Cited by 177 · see citing works
The gut microbiota in cancer immunity and immunotherapy
Xie, M., Li, X., Lau, H. C.-H., & Yu, J. (2025) · Cellular and Molecular Immunology · doi:10.1038/s41423-025-01326-2 · Cited by 125 · see citing works
Díez-Martín, E., Hernández-Suárez, L., Muñoz‐Villafranca, C., Martin–Souto, L., Astigarraga, E., Ramirez‐Garcia, A., & Barreda‐Gómez, G. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25137062 · Cited by 121 · see citing works
Enhancing intestinal barrier efficiency: A novel metabolic diseases therapy
Zhang, Y., Xiao, Z., Yu, X., Novák, P., Gui, Q., & Yin, K. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1120168 · Cited by 110 · see citing works
Liu, X., Liu, Y., Liu, J., Zhang, H., Shan, C., Guo, Y., Gong, X., Cui, M., Li, X., & Tang, M. (2023) · Neural Regeneration Research · doi:10.4103/1673-5374.382223 · Cited by 69 · see citing works
The Role of Bacteriophages in the Gut Microbiota: Implications for Human Health
Emencheta, S. C., Olovo, C. V., Eze, O. C., Kalu, C. F., Berebon, D. P., Onuigbo, E. B., Vila, M. M. D. C., Balcão, V. M., & Attama, A. A. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15102416 · Cited by 68 · see citing works
Recent advances on emerging nanomaterials for diagnosis and treatment of inflammatory bowel disease
Fu, W., Xu, L., Chen, Z., Kan, L., Ma, Y., Qian, H., & Wang, W. (2023) · Journal of Controlled Release · doi:10.1016/j.jconrel.2023.09.033 · Cited by 51 · see citing works
Liang, T., Liang, Z., Wu, S., Ding, Y., Wu, Q., & Gu, B. (2023) · Medicine Advances · doi:10.1002/med4.6 · Cited by 46 · see citing works
Oluwarinde, B. O., Ajose, D. J., Abolarinwa, T. O., Montso, P. K., du Preez, I., Njom, H. A., & Ateba, C. N. (2023) · Foods · doi:10.3390/foods12213989 · Cited by 48 · see citing works
The emerging roles of neuroactive components produced by gut microbiota
Dezfouli, M. A., Rashidi, S. K., Yazdanfar, N., Khalili, H., Goudarzi, M., Saadi, A., & Kiani, A. A. (2024) · Molecular Biology Reports · doi:10.1007/s11033-024-10097-4 · Cited by 45 · see citing works
García-Gutiérrez, E., O’Mahony, A. K., dos Santos, R. S., Marroquí, L., & Cotter, P. D. (2024) · Gut Microbes · doi:10.1080/19490976.2024.2401654 · Cited by 42 · see citing works
Hong, D., Zhang, C., Wu, W., Lu, X., & Zhang, L. (2023) · Frontiers in Neurology · doi:10.3389/fneur.2023.1133546 · Cited by 38 · see citing works
Gao, J., Cao, B., Zhao, R., Li, H., Xu, Q.-X., & Wei, B. (2023) · Pharmaceuticals · doi:10.3390/ph16091216 · Cited by 32 · see citing works
The gut microbes in inflammatory bowel disease: Future novel target option for pharmacotherapy
Yuan, S., Wang, K.-S., Meng, H., Hou, X.-T., Xue, J.-C., Liu, B., Cheng, W., Li, J., Zhang, H., Nan, J., et al. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.114893 · Cited by 34 · see citing works
Huang, B., An, H., Gui, M., Qiu, Y., Xu, W., Chen, L., Li, Q., Yao, S., Lin, S., Khrustaleva, T. A., et al. (2025) · Chinese Herbal Medicines · doi:10.1016/j.chmed.2025.04.001 · Cited by 30 · see citing works
Nutritional strategies to reduce intestinal cell apoptosis by alleviating oxidative stress
Li, B., Zhang, X., Zhang, Q., Zheng, T., Li, Q., Yang, S., Shao, J., Guan, W., & Zhang, S. (2024) · Nutrition Reviews · doi:10.1093/nutrit/nuae023 · Cited by 29 · see citing works
Gut‑liver axis in liver disease: From basic science to clinical treatment (Review)
Wang, J., Wang, X., Zhuo, E., Chen, B., & Chan, S. (2024) · Molecular Medicine Reports · doi:10.3892/mmr.2024.13375 · Cited by 29 · see citing works
Xu, J., Tu, M., Fan, X., Guo, Y., Zhang, T., Zeng, X., Cai, Z., Wu, Z. F., & Pan, D. (2023) · Food Science and Human Wellness · doi:10.26599/fshw.2022.9250077 · Cited by 28 · see citing works
Bacterial defense mechanisms against bacteriophages: an evolutionary arms race
Ibrahim, R., & Aranjani, J. M. (2026) · Archives of Microbiology · doi:10.1007/s00203-026-04785-x · Cited by 29 · see citing works
Yang, L., Li, X.-M., Duan, H.-Y., Yang, K., & Ye, J. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1398652 · Cited by 25 · see citing works
Wei, H., Sun, M., Wang, R., Zeng, H., Zhao, B., & Jin, S. (2024) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.18239 · Cited by 24 · see citing works
Chlorogenic acid and intestinal health: mechanistic insights and therapeutic applications
Xu, J., Zhao, X., Yang, S., Tang, M., Zhao, R., & Hu, S. (2025) · Food & Function · doi:10.1039/d5fo00853k · Cited by 23 · see citing works
Xue, P., Sang, R., Li, N., Du, S., Kong, X., Tai, M., Jiang, Z., & Chen, Y. (2023) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2023.1119037 · Cited by 24 · see citing works
The Post-Antibiotic Era: A New Dawn for Bacteriophages
Jin, Y., Li, W., Zhang, H., Ba, X., Li, Z., & Zhou, J. (2023) · Biology · doi:10.3390/biology12050681 · Cited by 21 · see citing works
Gut microbiome associated dysbiosis: Limited regimens and expanding horizons of phage therapy
Singha, B., Rawat, B. S., Venkataraman, R., Nair, T., Rosenn, E. H., & Soni, V. (2023) · Aspects of Molecular Medicine · doi:10.1016/j.amolm.2023.100029 · Cited by 22 · see citing works
Cieślik, M., Wójcicki, M., Migdał, P., Grygiel, I., Bajrak, O., Orwat, F., Górski, A., & Jończyk‐Matysiak, E. (2025) · Medical Microbiology and Immunology · doi:10.1007/s00430-025-00844-0 · Cited by 20 · see citing works
Qi, M., & Tay, A. K. P. (2025) · Nanoscale · doi:10.1039/d5nr02249e · Cited by 22 · see citing works
Wójcicki, M., Sokołowska, B., Górski, A., & Jończyk‐Matysiak, E. (2025) · Viruses · doi:10.3390/v17060778 · Cited by 18 · see citing works
Mafe, A. N., & Büsselberg, D. (2025) · Pharmaceutics · doi:10.3390/pharmaceutics17070820 · Cited by 18 · see citing works
SCHWARTZ, J. L., Capistrano, K. J., Gluck, J., Hezarkhani, A., & Naqvi, A. R. (2024) · Reviews in Medical Virology · doi:10.1002/rmv.2543 · Cited by 20 · see citing works
The role of bacteriophages in shaping bacterial composition and diversity in the human gut
Alkhalil, S. S. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1232413 · Cited by 17 · see citing works
Patil, R., Arora, S., Kumar, D., & Agrawal, A. K. (2025) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.70021 · Cited by 16 · see citing works
Does Phage Therapy Need a Pan-Phage?
Bozidis, P., Markou, E., Gouni, A., & Gartzonika, K. (2024) · Pathogens · doi:10.3390/pathogens13060522 · Cited by 16 · see citing works
Pan, X., Liu, P., Zhang, Y.-J., Zhang, H.-K., Wei, H., Jiang, J., Hui-yan, Shang, E., Li, W.-W., Wang, Y., et al. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.126930 · Cited by 16 · see citing works
The insights into the phage communities of fermented foods in the age of viral metagenomics
Zhang, H., Zhang, H., Du, H., Yu, X., & Xu, Y. (2024) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2023.2299323 · Cited by 14 · see citing works
Santacroce, L., Colella, M., Charitos, I. A., Domenico, M. D., Palmirotta, R., & Jirillo, E. (2023) · Metabolites · doi:10.3390/metabo13030461 · Cited by 18 · see citing works
The Microbiome and Metabolic Dysfunction-Associated Steatotic Liver Disease
Beyoğlu, D., & Idle, J. R. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26072882 · Cited by 13 · see citing works
Zhang, S., Easwaran, M., Elafify, M., Mahmoud, A. A., Wang, X., & Ahn, J. (2025) · Applied and Environmental Microbiology · doi:10.1128/aem.01899-25 · Cited by 16 · see citing works
San-Martín, M. I., Chamizo‐Ampudia, A., Sanchiz, Á., Ferrero, M. Á. M., Martı́nez-Blanco, H., Rodrı́guez-Aparicio, L. B., & Navasa, N. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26104818 · Cited by 15 · see citing works
Wang, X., Li, J., Ge, Z., Fan, J., Ma, D., Cao, H., Shen, J., Wang, Y., Liu, Z., Gomaa, S. E., et al. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1672198 · Cited by 10 · see citing works
Factors influencing gut microbial colonization: A host-microbe-environment interaction perspective
Zhao, Y., Ren, Z., Xu, Q., Zhu, T., Hu, H., Fu, Y., Jiang, J., & Zhai, Q. (2026) · Current Research in Food Science · doi:10.1016/j.crfs.2026.101361 · Cited by 13 · see citing works
Nazir, M. M., Ghaffar, W., Mustafa, G., Saeed, S., Ijaz, M. U., & Ashraf, A. (2025) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-025-04464-6 · Cited by 13 · see citing works
Targeting bacterial persistence with bacteriophages: a next-generation antimicrobial strategy
Kim, S. G. (2025) · Virology · doi:10.1016/j.virol.2025.110649 · Cited by 10 · see citing works
Microbiome and gut-liver interactions: From mechanisms to therapies
Anis, M. A., Shahid, Y., Majeed, A. A., & Abid, S. (2025) · World Journal of Gastroenterology · doi:10.3748/wjg.v31.i40.111409 · Cited by 11 · see citing works
The Novel Role of Phage Particles in Chronic Liver Diseases
Chen, L., Hou, X., & Chu, H. (2023) · Microorganisms · doi:10.3390/microorganisms11051181 · Cited by 10 · see citing works
Exploring bacteriophages to combat gut dysbiosis: A promising new frontier in microbiome therapy
Easwaran, M., Abdelrahman, F. I., El‐Shibiny, A., Venkidasamy, B., Thiruvengadam, M., Sivalingam, P., Ganapathy, D. M., Ahn, J., & Shin, H. (2025) · Microbial Pathogenesis · doi:10.1016/j.micpath.2025.108008 · Cited by 9 · see citing works
Microbiome engineering: unlocking therapeutic potential in inflammatory bowel disease
Chen, K., Huang, L.-B., Yang, M., Yue, N.-N., Luo, D., Zhang, Y., Tian, C., Song, Y., Wei, D., Shi, R., et al. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1610029 · Cited by 11 · see citing works
Xu, F., Yu, P., Wu, H., Liu, M., Liu, H., Zeng, Q., Wu, D., & Wang, X. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1295822 · Cited by 9 · see citing works
Zhang, M., Zhou, Y., Cui, X., & Zhu, L. (2024) · Microorganisms · doi:10.3390/microorganisms12040713 · Cited by 8 · see citing works
Wójcicki, M., Cieślik, M., Shymialevich, D., Emanowicz, P., Średnicka, P., Cieślak, H., Ilczuk, T., Koperski, Ł., & Sokołowska, B. (2025) · Microbial Pathogenesis · doi:10.1016/j.micpath.2025.107921 · Cited by 8 · see citing works
Bacteriophages, Antibiotics and Probiotics: Exploring the Microbial Battlefield of Colorectal Cancer
Volovat, C. C., Cosovanu, M. A., Ostafe, M.-R., Augustin, I. G., Volovat, C., Georgescu, B., & Volovat, S. R. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26167837 · Cited by 8 · see citing works
Colorectal cancer and gut viruses: a visualized analysis based on CiteSpace knowledge graph
Chu, J., Jing, Z., Wu, Y., Jinlong, D., Pan, Y., Quan, Q., & Han, S. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1239818 · Cited by 8 · see citing works
Bacteriophages for the Treatment of Resistant Bacterial Infectious Diseases
Rezaei, A. R. (2024) · Journal of Bacteriology and Virology · doi:10.4167/jbv.2024.54.2.084 · Cited by 7 · see citing works
Zhang, Y., Zhu, Y., Li, M., Zhang, M., Shou, D., & Tong, P. (2025) · Nutrition and Diabetes · doi:10.1038/s41387-025-00374-x · Cited by 7 · see citing works
Ecological drivers of CRISPR immune systems
Xiao, W., Weissman, J., & Johnson, P. L. F. (2024) · mSystems · doi:10.1128/msystems.00568-24 · Cited by 7 · see citing works
Wójcicki, M., Shymialevich, D., Średnicka, P., Emanowicz, P., Ostrowska, A., Cieślak, H., & Sokołowska, B. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252312930 · Cited by 7 · see citing works
Melatonin: The potential avenues in dentistry
Sanidhya, S., Kamath, D. G., Sinha, A., & Kamath, D. (2025) · F1000Research · doi:10.12688/f1000research.159942.1 · Cited by 7 · see citing works
Bacteriophage-based techniques for elucidating the function of zebrafish gut microbiota
Jia, P., Yang, Y., Junaid, M., Jia, H.-J., Li, W., & Pei, D. (2023) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-023-12439-x · Cited by 7 · see citing works
Phage-Microbiota Interactions in the Gut: Implications for Health and Therapeutic Strategies
Naderian, R., Alibabaei, F., Paraandavaji, E., Dehghan, P., & Eslami, M. (2025) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-025-10784-z · Cited by 6 · see citing works
Wei, X., Zhang, X., Cui, M., Huang, L., Gao, D., & Hua, S. (2025) · Reviews in Cardiovascular Medicine · doi:10.31083/rcm36386 · Cited by 6 · see citing works
Gut virome and diabetes: discovering links, exploring therapies
Fang, L., & Ning, J. (2024) · Archives of Microbiology · doi:10.1007/s00203-024-04068-3 · Cited by 6 · see citing works
The role of bacteriophage in inflammatory bowel disease and its therapeutic potential
Xiao, Y.-Y., Yue, X., Zhang, X.-P., Yang, Y., Zhang, Y., & Sun, L. (2025) · Critical reviews in microbiology · doi:10.1080/1040841x.2025.2492154 · Cited by 5 · see citing works
Ecological presence and functional role of bacteriophages in fermented vegetables
Lin, X., Deng, C., Shu, Y., Li, S., Song, Y., Kong, H., Liang, Z., Liu, L., & Rao, Y. (2025) · Food Microbiology · doi:10.1016/j.fm.2025.104884 · Cited by 5 · see citing works
Emerging analytical techniques for determination of foodborne pathogens and toxins: a review
Haddad, M. A., Tarawneh, H., Abu-Romman, S. M., Akhter, N., & Rather, J. A. (2025) · Discover Food · doi:10.1007/s44187-025-00590-5 · Cited by 5 · see citing works
Ding, B., Fan, M., Shi, Y., Chen, X., & Duan, Y. (2025) · Microbiome Research Reports · doi:10.20517/mrr.2025.62 · Cited by 6 · see citing works
Gomes, N., Sá, L. C. E. F., Alves, N., Dallago, B. S. L., Moraes, A. S., Carvalho, J. L., Nitz, N., Hagström, L., Braz, S. V., Machado, E. R., et al. (2023) · Acta Tropica · doi:10.1016/j.actatropica.2023.107018 · Cited by 7 · see citing works
Liang, L., Huang, J., Cui, K., Li, P., Shi, W., Lin, F., Hao, G., & Sun, S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232112830 · Cited by 5 · see citing works
Wu, Z., Song, X., Zhang, Y., & Lin, R. (2025) · Advanced Composites and Hybrid Materials · doi:10.1007/s42114-025-01423-w · Cited by 4 · see citing works
Zhao, X., Li, R., Zhao, J., Sun, R., Zhang, S., Pan, Q., Lu, H., & Chai, J. (2025) · Medicine Bulletin · doi:10.1002/mdb2.70012 · Cited by 4 · see citing works
Microbial dysbiosis in cholangiocarcinoma
Liu, Y., Huang, S., Zhang, Y., Zhang, Y., Xu, Y., Tang, Y., Guo, S., & Zhang, Z. (2026) · Frontiers in Microbiology · doi:10.3389/fmicb.2026.1727736 · Cited by 4 · see citing works
Intestinal Microbes, Metabolites, and Hormones in Alcohol-Associated Liver Disease
Wang, R., Ma, F., Yin, D., Wang, H., & Wei, X. (2025) · Seminars in Liver Disease · doi:10.1055/a-2601-9480 · Cited by 4 · see citing works
Monocytes serve as Shiga toxin carriers during the development of hemolytic uremic syndrome
Sun, X., Qu, S., Zhou, F., Shi, F., Wu, Y., Gu, L., Liu, M., Bian, Z., Shi, L., Liu, Z., et al. (2025) · Cellular & Molecular Biology Letters · doi:10.1186/s11658-025-00689-8 · Cited by 4 · see citing works
Akhtar, N., Jain, C., Chauhan, S. B., & Singh, I. P. (2025) · Medicine in Microecology · doi:10.1016/j.medmic.2025.100148 · Cited by 4 · see citing works
Maas, E., Penders, J., & Venema, K. (2023) · Microbial Pathogenesis · doi:10.1016/j.micpath.2023.106061 · Cited by 4 · see citing works
Yang, L., Xu, Y., & Wang, X. (2026) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1723549 · Cited by 3 · see citing works
Therapeutic Options for Diarrheagenic Escherichia coli
Balestracci, A., Luz, D., Sacerdoti, F., Amaral, M. M., Gomez-Duarte, O. G., & Piazza, R. M. F. (2023) · Springer eBooks · doi:10.1007/978-3-031-29882-0_15 · Cited by 3 · see citing works
Gut microbial subtypes and clinicopathological value for colorectal cancer
Han, S., Jing, Z., Song, Y., Wu, X., Yu, X., Ye, T., Chu, J., Qu, Z., Wu, Y., Han, S., et al. (2024) · Cancer Medicine · doi:10.1002/cam4.70180 · Cited by 3 · see citing works
Viewing Psychiatric Disorders Through Viruses: Simple Architecture, Burgeoning Implications
Kong, L., Zhu, B., Zhuang, Y., Lai, J., & Hu, S. (2025) · Neuroscience Bulletin · doi:10.1007/s12264-025-01443-y · Cited by 2 · see citing works
Yuan, S., Zhu, H., Yu, M., Jia, H., Peng, S., & Ma, Y. (2026) · Cell Host & Microbe · doi:10.1016/j.chom.2026.02.017 · Cited by 2 · see citing works
Xie, J., Deng, S., Zhang, X., Zhang, L., & Jia, X. (2026) · iScience · doi:10.1016/j.isci.2026.115483 · Cited by 2 · see citing works
Cheng, H., & Wong, C. C. (2026) · Molecular Cancer · doi:10.1186/s12943-026-02698-3 · Cited by 2 · see citing works
The gut microbiome in colorectal cancer: molecular paradigms and translational frontiers
Liu, Y., & Mei, D. (2026) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2026.1864299 · Cited by 2 · see citing works
A comprehensive review on CRISPR-Cas9 in revolutionizing food and agricultural sectors
Haddad, M. A., Abu-Romman, S. M., Rather, J. A., Akhter, N., Khan, B. A., & Dalaeen, S. (2025) · Food and Humanity · doi:10.1016/j.foohum.2025.100679 · Cited by 2 · see citing works
Wu, X., Liu, X., Xu, W., Chen, W., Zhong, Z., Tan, H., & Xiang, T. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1461259 · Cited by 1 · see citing works
Jyotirmayee, Khanda, R., & Verma, M. (2024) · Springer eBooks · doi:10.1007/978-981-97-5272-0_32 · Cited by 1 · see citing works
Human Gut Bacteriophageome: Insights Into Drug Resistance Mechanisms in Tuberculosis
Jafari, E., Azizian, R., Tabasi, M., Banakar, M., & Lankarani, K. B. (2025) · Interdisciplinary Perspectives on Infectious Diseases · doi:10.1155/ipid/8811027 · Cited by 2 · see citing works
Complete genome sequence of a Kayfunavirus bacteriophage identified in Blantyre, Malawi
Mhango, C., Ndovie, W., Zuza, A. M., Chinyama, E., Kawonga, F., Matambo, E., Kumwenda, B., Kamng’ona, A. W., Chaguza, C., Nyaga, M. M., et al. (2025) · Microbiology Resource Announcements · doi:10.1128/mra.00867-25 · Cited by 1 · see citing works
El‐Daly, S. M., Fayed, B. E., Talaat, R. M., Gouhar, S. A., Fahmy, C. A., El-Jawad, A. M. A., Hamdy, N. Μ., & Elmageed, Z. Y. A. (2026) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-3-032-08530-6_2 · Cited by 1 · see citing works
Cai, W., Wang, P., Zhang, R., Dong, L., Li, J., Wang, M., Wang, L., Shao, X., Jing, T., Hu, Y., et al. (2026) · Food Science & Nutrition · doi:10.1002/fsn3.71435 · Cited by 1 · see citing works
Li, L., Wang, H., Gao, Y., Zhang, B., & Chen, Y. (2026) · BMC Microbiology · doi:10.1186/s12866-025-04682-1 · Cited by 1 · see citing works
Influence of the Gut-Brain Axis on Psychiatric Comorbidity in Inflammatory Bowel Disease
Borrego-Ruiz, A., & Borrego, J. J. (2026) · Psychiatry International · doi:10.3390/psychiatryint7020052 · Cited by 1 · see citing works
Structural and Functional Diversity of RNA ‐Containing Toxin–Antitoxin Systems
Dutta, H., Noor, S., Nadig, K., & Singh, M. (2026) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.70042 · Cited by 1 · see citing works
Li, X., Wu, Y., Chen, S., Deng, C., Cheng, S., Yan, Z., & Qiu, G. (2025) · Archives of Dermatological Research · doi:10.1007/s00403-025-03857-0 · Cited by 2 · see citing works
Engineering the microbiome: A novel frontier in inflammatory bowel disease treatment
Chen, K., Huang, L., Yang, M., Yue, N., Zhang, Y., Tian, C., Wei, D., Shi, R., Liang, Y., Yao, J., et al. (2025) · Chinese Medical Journal · doi:10.1097/cm9.0000000000003563 · Cited by 1 · see citing works
Bacteria, Viruses, and the Microbiome
Anisman, H., Hayley, S. P., & Kusnecov, A. W. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-23565-8.00020-x
Monocytes Serve as Shiga Toxin Carrier During the Development of Hemolytic Uremic SyndromePreprint
Sun, X., Qu, S., Shi, F., Wu, Y., Gu, L., Liu, M., Bian, Z., Shi, L., Liu, Z., Liu, Y., et al. (2024) · SSRN Electronic Journal · doi:10.2139/ssrn.4802682
Li, W., Yu, M., Lin, Q., Xiong, Y., Yao, Y., Xu, H., He, G., & Zhao, J. (2024) · doi:10.22541/au.171827167.71833789/v1
Szymczak, A., Gembara, K., Majewska, J., Miernikiewicz, P., Ferenc, S., Gnus, J. J., Kłak, M., Jędruchniewicz, N., Witkiewicz, W., & Dąbrowska, K. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.06.16.598898
Le viróme humain : un écosystème viral dans notre corps
Ottmann, M. (2024) · Revue Francophone des Laboratoires · doi:10.1016/s1773-035x(24)76115-2
- Authors
- Shuwen, H., & Kefeng, D.
- Affiliations
- Key Laboratory of Cancer Prevention and Intervention, Ministry of Education, The Second Affiliated Hospital, Zhejiang University School of Medicine
- ORCID
- Shuwen, Han
- Venue
- Gut Microbes
- Publisher
- Informa UK Limited
- Published
- 2022-08-29
- Volume
- 14
- Issue
- 1
- Pages
- 2113717-2113717
- ISSN
- 1949-0976 (ISSN-L)
- 1949-0984
- PMC
- PMC9427043
- OpenAlex
- W4293469418
- Cited by
- 124
- References
- 154
- Citations by year
- 2026: 29 · 2025: 43 · 2024: 28 · 2023: 23 · 2022: 1
- FWCI
- 2.19
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Gut Microbes (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- the Major Science and Technology Projects for Medical and Health Care of Zhejiang Province
- National Natural Science Foundation of China (No. 82072624)
- Topics
- Physical Sciences › Environmental Science › Ecology › Bacteriophages and microbial interactions
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Physical Sciences › Environmental Science › Water Science and Technology › Fecal contamination and water quality
- Keywords
- bacteriophage-bacteria interactions, gut microbiota, phage therapy, phage exclusion, restriction-modification systems, CRISPR-Cas, superinfection exclusion, inflammatory bowel disease, colorectal cancer, alcoholic liver disease, rheumatoid arthritis, graft-versus-host disease
- MeSH terms
- Gastrointestinal Microbiome, Bacteria, Bacteriophages, Diabetes Mellitus, Type 2, Escherichia coli, Humans, Silver, Proteasome Endopeptidase Complex, Metal Nanoparticles
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