Restoring tracheal defects in a rabbit model with tissue engineered patches based on TGF-β3-encapsulating electrospun poly( l -lactic acid-co-ε-caprolactone)/collagen scaffolds

Electrospun gelatin/PCL and collagen/PLCL scaffolds for vascular tissue engineering

Fu, W. E., Liu, Z., Feng, B., Hu, R., He, X., Wang, H., Yin, M., Huang, H., Zhang, H., & Wang, W. (2014) · International Journal of Nanomedicine · doi:10.2147/ijn.s61375 · Cited by 274 · see citing works

Engineering ear-shaped cartilage using electrospun fibrous membranes of gelatin/polycaprolactone

Xue, J., Feng, B., Zheng, R., Yang, L., Zhou, G., Liu, W. X., Cao, Y., Zhang, Y., & Zhang, W. J. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2012.12.011 · Cited by 163 · see citing works

Electrospun Silk Fibroin Nanofibrous Scaffolds with Two-Stage Hydroxyapatite Functionalization for Enhancing the Osteogenic Differentiation of Human Adipose-Derived Mesenchymal Stem Cells

Ko, E., Lee, J. S., Kim, H., Yang, S. Y., Yang, D., Yang, K., Lee, J., Shin, J., Yang, H. S., Ryu, W., et al. (2018) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.7b03328 · Cited by 150 · see citing works

Collagen‐coated nano‐electrospun PCL seeded with human endometrial stem cells for skin tissue engineering applications

Sharif, S., Ai, J., Azami, M., Verdi, J., Atlasi, M. A., Shirian, S., & Samadikuchaksaraei, A. (2017) · Journal of Biomedical Materials Research Part B Applied Biomaterials · doi:10.1002/jbm.b.33966 · Cited by 100 · see citing works

Electrospun gelatin/polycaprolactone nanofibrous membranes combined with a coculture of bone marrow stromal cells and chondrocytes for cartilage engineering

Fu, W. E., He, X., Feng, B., Huang, C. ‐. C., Wang, H., Ge, Y., Hu, R., Yin, M., Xu, Z., Wang, W., et al. (2015) · International Journal of Nanomedicine · doi:10.2147/ijn.s79461 · Cited by 77 · see citing works

Evaluation of the potential of rhTGF- β3 encapsulated P(LLA-CL)/collagen nanofibers for tracheal cartilage regeneration using mesenchymal stems cells derived from Wharton's jelly of human umbilical cord

Wang, J., Sun, B., Tian, L., He, X., Gao, Q., Wu, T. S., Ramakrishna, S., Zheng, J., & Mo, X. (2016) · Materials Science and Engineering C · doi:10.1016/j.msec.2016.09.044 · Cited by 69 · see citing works

Comparisons of Rabbit Bone Marrow Mesenchymal Stem Cell Isolation and Culture Methods In Vitro

Zhang, W., Zhang, F., Shi, H., Tan, R.-B., Han, S. H., Ye, G., Pan, S., Sun, F., & Liu, X. (2014) · PLoS ONE · doi:10.1371/journal.pone.0088794 · Cited by 67 · see citing works

Physicochemical and biological characteristics of BMP-2/IGF-1-loaded three-dimensional coaxial electrospun fibrous membranes for bone defect repair

Yin, L., Yang, S., He, M., Chang, Y., Wang, K., Zhu, Y., Liu, Y., Chang, Y., & Yu, Z. (2017) · Journal of Materials Science Materials in Medicine · doi:10.1007/s10856-017-5898-3 · Cited by 48 · see citing works

Dual delivery of active antibactericidal agents and bone morphogenetic protein at sustainable high concentrations using biodegradable sheath-core-structured drug-eluting nanofibers

Hsu, Y., Lin, C.-T., Yu, Y., Chou, Y., Liu, S., & Chan, E. (2016) · International Journal of Nanomedicine · doi:10.2147/ijn.s107250 · Cited by 46 · see citing works

Mechanical evaluation of gradient electrospun scaffolds with 3D printed ring reinforcements for tracheal defect repair

Ott, L. M., Zabel, T. A., Walker, N. K., Farris, A. L., Chakroff, J., Ohst, D. G., Johnson, J. K., Gehrke, S. H., Weatherly, R. A., & Detamore, M. S. (2016) · Biomedical Materials · doi:10.1088/1748-6041/11/2/025020 · Cited by 44 · see citing works

Electrospun Collagen–Poly( L -Lactic Acid-Co-ε-Caprolactone) Membranes for Cartilage Tissue Engineering

He, X., Fu, W. E., Feng, B., Wang, H., Liu, Z., Yin, M., Wang, W., & Zheng, J. (2013) · Regenerative Medicine · doi:10.2217/rme.13.29 · Cited by 43 · see citing works

Exogenous Heparan Sulfate Enhances the TGF‐β3‐Induced Chondrogenesis in Human Mesenchymal Stem Cells by Activating TGF‐β/Smad Signaling

Chen, J., Wang, Y., Chen, C., Lian, C., Zhou, T., Gao, B., Wu, Z., & Xu, C. (2015) · Stem Cells International · doi:10.1155/2016/1520136 · Cited by 40 · see citing works

Surgical management of congenital tracheal stenosis associated with tracheal bronchus and congenital heart disease

Wang, S., Zhang, H., Zhu, L., Zhen, J., Liu, J., & Xu, Z. (2015) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezv317 · Cited by 38 · see citing works

Repair of large airway defects with bioprosthetic materials

Udelsman, B. V., Eaton, J. C., Muniappan, A., Morse, C. R., Wright, C. D., & Mathisen, D. J. (2016) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2016.07.074 · Cited by 34 · see citing works

Chondrogenesis of Embryonic Stem Cell‐Derived Mesenchymal Stem Cells Induced by TGFβ1 and BMP7 Through Increased TGFβ Receptor Expression and Endogenous TGFβ1 Production

Lee, P. T., & Li, W. (2016) · Journal of Cellular Biochemistry · doi:10.1002/jcb.25623 · Cited by 32 · see citing works

Core–Shell Electrospun Fibers Encapsulating Chromophores or Luminescent Proteins for Microscopically Controlled Molecular Release

Romano, L., Camposeo, A., Manco, R., Moffa, M., & Pisignano, D. (2016) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.5b00560 · Cited by 30 · see citing works

Surgical treatment of non-malignant laryngotracheal stenosis

Rubikas, R., Matukaitytė, I., Jelisiejevas, J. J., & Račkauskas, M. (2014) · European Archives of Oto-Rhino-Laryngology · doi:10.1007/s00405-014-2981-y · Cited by 28 · see citing works

Electrospun Collagen/Poly(L-lactic acid-co-ε-caprolactone) Hybrid Nanofibrous Membranes Combining with Sandwich Construction Model for Cartilage Tissue Engineering

He, X., Fu, W. E., Feng, B., Wang, H., Liu, Z., Yin, M., Wang, W., & Zheng, J. (2013) · Journal of Nanoscience and Nanotechnology · doi:10.1166/jnn.2013.7436 · Cited by 17 · see citing works

Reconstruction of Large Tracheal Defects in a Canine Model: Lessons Learned

Zang, M., Chen, K., & Yu, P. (2010) · Journal of Reconstructive Microsurgery · doi:10.1055/s-0030-1249605 · Cited by 12 · see citing works

Effect of Structural Differences in Collagen Sponge Scaffolds on Tracheal Epithelium Regeneration

Nakaegawa, Y., Nakamura, R., Tada, Y., Nomoto, Y., Imaizumi, M., Suzuki, R., Nakamura, T., & Omori, K. (2015) · Annals of Otology Rhinology & Laryngology · doi:10.1177/0003489415599991 · Cited by 11 · see citing works

A Novel Animal Model for Hyperdynamic Airway Collapse

Tsukada, H., O’Donnell, C. R., Garland, R. E., Herth, F. J. F., DeCamp, M. M., & Ernst, A. (2010) · CHEST Journal · doi:10.1378/chest.10-0165 · Cited by 10 · see citing works

Reconstruction of the Lower Trachea Using a Pedicled Autologous Bronchial Flap

Chen, Q., Jiang, G., Ding, J.-A., Tong, W.-P., & Chen, X. (2010) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2010.01.059 · Cited by 8 · see citing works

Mesenchymal Stem Cells for Regenerative Medicine

Han, Y., Li, X., Zhang, Y., Han, Y., Chang, F., & Ding, J. (2019) · Cells · doi:10.3390/cells8080886 · Cited by 1,093 · see citing works

miR-381-abundant small extracellular vesicles derived from kartogenin-preconditioned mesenchymal stem cells promote chondrogenesis of MSCs by targeting TAOK1

Jing, H., Zhang, X., Luo, K., Luo, Q., Yin, M., Wang, W., Zhu, Z., Zheng, J., & He, X. (2019) · Biomaterials · doi:10.1016/j.biomaterials.2019.119682 · Cited by 68 · see citing works

Kartogenin preconditioning commits mesenchymal stem cells to a precartilaginous stage with enhanced chondrogenic potential by modulating JNK and β‐catenin–related pathways

Jing, H., Zhang, X., Gao, M., Luo, K., Fu, W. E., Yin, M., Wang, W., Zhu, Z., Zheng, J., & He, X. (2019) · The FASEB Journal · doi:10.1096/fj.201802137rrr · Cited by 54 · see citing works

An Avascular Niche Created by Axitinib‐Loaded PCL/Collagen Nanofibrous Membrane Stabilized Subcutaneous Chondrogenesis of Mesenchymal Stromal Cells

Ji, T.-J., Feng, B., Shen, J., Zhang, M., Hu, Y., Jiang, A., Zhu, D., Chen, Y., Ji, W., Zhang, Z., et al. (2021) · Advanced Science · doi:10.1002/advs.202100351 · Cited by 47 · see citing works

Converging 3D Printing and Electrospinning: Effect of Poly( l ‐lactide)/Gelatin Based Short Nanofibers Aerogels on Tracheal Regeneration

Yuan, Z., Ren, Y., Shafiq, M., Chen, Y., Tang, H., Li, B., El-Newehy, M. H., El‐Hamshary, H., Morsi, Y., Zheng, H. W., et al. (2021) · Macromolecular Bioscience · doi:10.1002/mabi.202100342 · Cited by 34 · see citing works

Tissue engineering applications in otolaryngology—The state of translation

Niermeyer, W. L., Rodman, C. P., Li, M. M., & Chiang, T. (2020) · Laryngoscope Investigative Otolaryngology · doi:10.1002/lio2.416 · Cited by 26 · see citing works

Organic and Synthetic Substitutes in Tracheal Reconstruction: A Scoping Review (2015–2025)

dos Santos, A. C., Holzlsauer, G. M., Parra, J. P. R. L. L., Candelária, R. A. Q., da Silva, T. S., Barreto, R. D. S. N., & Miglino, M. A. (2025) · Bioengineering · doi:10.3390/bioengineering12070704 · Cited by 9 · see citing works

Artificial Intelligence (AI) Based Analysis ofIn VivoPolymers and Collagen Scaffolds Inducing Vascularization

Salvante, E. R. G., Popoiu, A. V., Barb, A. C., Cosma, A. A., Fenesan, M. P., Saxena, A. K., Popoiu, T. A., Boia, E. S., Stănciulescu, M. C., Caplar, B. D., et al. (2024) · In Vivo · doi:10.21873/invivo.13481 · Cited by 8 · see citing works

Artificial trachea design, construction, and application: Materials, cells, and growth factors

Feng, X., Hu, Y., Cao, L., & Liu, L. (2023) · Applied Materials Today · doi:10.1016/j.apmt.2023.101968 · Cited by 7 · see citing works

Application of PLCL as a biodegradable polymer in biomedical engineering

Zhao, Y., & Liu, H. (2026) · Journal of Materials Science Materials in Medicine · doi:10.1007/s10856-026-07016-3 · Cited by 7 · see citing works

A Biofunctional Hydrogel/Nanofiber Bilayer Scaffold Delivering EGF and TGFβ3 for Advanced Nasal Tissue Reconstruction

YILMAZ, H., Gursoy, S., Torkay, G., Saraj, S., Karzoun, L., Kose, A., Insel, M. A., Yıldırım, R., Bal‐Öztürk, A., Koyuncu, A. C. Ç., et al. (2025) · Macromolecular Materials and Engineering · doi:10.1002/mame.202500164 · Cited by 4 · see citing works

The Development of Lung Tissue Engineering: From Biomaterials to Multicellular Systems

Ma, J., Wu, C., & Xu, J. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202401025 · Cited by 4 · see citing works

Delivery of TGFβ3 from Magnetically Responsive Coaxial Fibers Reduces Spinal Cord Astrocyte Reactivity In Vitro

Funnell, J. L., Fougere, J., Zahn, D., Dutz, S., & Gilbert, R. J. (2024) · Advanced Biology · doi:10.1002/adbi.202300531 · Cited by 3 · see citing works

Tracheal Regeneration: Recent Progress in the Application of Stem Cells in Tracheal Bioengineering

Ganji, F., Billan, F. L., Haykal, S., & Karoubi, G. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27062891 · Cited by 2 · see citing works

Current status, trend and progress of stem cells in tracheal tissue engineering research: an overview and perspectives

Zhu, J., Bao, M., Shan, Y., Lü, Y., Shen, Z., Chen, W., Chen, H., Guo, L., & Shi, H. (2025) · Stem Cell Research & Therapy · doi:10.1186/s13287-025-04770-z · Cited by 3 · see citing works

Preparation and Performance Evaluation of Short Fiber/Hydrogel Composite Tracheal Cartilage Ring-Shaped Scaffolds

韩, 凤. (2026) · Hans Journal of Biomedicine · doi:10.12677/hjbm.2026.163040

Engineering an artificial trachea: Quantitative benchmarks and modular strategies for mechanics, epithelialization, and vascular integration

Xu, Y., Dai, H., Ye, Q., Zhang, W., Na, W., Xiong, L., & Guo, R. (2026) · FlexMat. · doi:10.1002/flm2.70136

Biodegradable electrospun patch containing cell adhesion or antimicrobial compounds for trachea repair in vivo

Townsend, J. M., Hukill, M. E., Fung, K.-M. A., Ohst, D. G., Johnson, J. K., Weatherly, R. A., & Detamore, M. S. (2019) · Biomedical Materials · doi:10.1088/1748-605x/ab5e1b · Cited by 19 · see citing works

An ectopic approach for engineering a vascularized tracheal substitute

Tsao, C., Ko, C., Yang, S., Yang, C., Brey, E. M., Huang, S., Chu, I., & Cheng, M. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.10.055 · Cited by 46 · see citing works

An animal model study for tissue-engineered trachea fabricated from a biodegradable scaffold using chondrocytes to augment repair of tracheal stenosis

Komura, M., Komura, H., Kanamori, Y., Tanaka, Y., Suzuki, K. H., Sugiyama, M., Nakahara, S., Kawashima, H., Hatanaka, A., Hoshi, K., et al. (2008) · Journal of Pediatric Surgery · doi:10.1016/j.jpedsurg.2008.08.038 · Cited by 95 · see citing works

Converging 3D Printing and Electrospinning: Effect of Poly( l ‐lactide)/Gelatin Based Short Nanofibers Aerogels on Tracheal Regeneration

Yuan, Z., Ren, Y., Shafiq, M., Chen, Y., Tang, H., Li, B., El-Newehy, M. H., El‐Hamshary, H., Morsi, Y., Zheng, H. W., et al. (2021) · Macromolecular Bioscience · doi:10.1002/mabi.202100342 · Cited by 34 · see citing works

Mechanical evaluation of gradient electrospun scaffolds with 3D printed ring reinforcements for tracheal defect repair

Ott, L. M., Zabel, T. A., Walker, N. K., Farris, A. L., Chakroff, J., Ohst, D. G., Johnson, J. K., Gehrke, S. H., Weatherly, R. A., & Detamore, M. S. (2016) · Biomedical Materials · doi:10.1088/1748-6041/11/2/025020 · Cited by 44 · see citing works