Implications of Antibiotic Resistance in Probiotics
Abstract
Collectively, many lactobacilli form a major group of health-promoting microorganisms. A subset of which are generally known as probiotics. Emergence of antibiotic-resistant strains is challenging human health and well-being, particularly antibiotic therapy for the treatment of bacterial infections. Lactobacilli may prevent gastrointestinal disruption during antibiotic therapy by helping to reestablish or maintain the normal microbiota of the intestine. To achieve this, lactobacilli must survive in the presence of coadministered antibiotics. Hence, antibiotic resistance of probiotics is an essential criterion for their screening and selection, provided of course that they do not pose a threat by way of the transfer of antibiotic resistance genes to other bacteria. This article addresses the types of antibiotic resistance and transfer mechanisms, the antibiotic resistance profile of probiotic lactobacilli, as well as the benefits associated and concerns raised with antibiotic resistance of probiotic bacteria.
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The natural resistance of probiotic strains may be advantageous as it promotes both therapeutic and preventive benefits when concomitantly administered with antibiotics and facilitates intestinal microbiota recovery.
“The natural resistance of probiotic strains may be advantageous as it promotes both therapeutic and preventive benefits when concomitantly administered with antibiotics and facilitates intestinal microbiota recovery [67].”
From Genomic Characterization of Lactiplantibacillus plantarum Strains: Potential Probiotics from Ethiopian Traditional Fermented Cottage Cheese (2024) · cites this paper as [67]
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A critical review of antibiotic resistance in probiotic bacteria
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“The natural resistance of probiotic strains may be advantageous as it promotes both therapeutic and preventive benefits when concomitantly administered with antibiotics and facilitates intestinal microbiota recovery [67].”
- Authors
- Jose, N. M., Bunt, C. R., & Hussain, M. A.
- Affiliations
- Lincoln University (NZ)
- Corresponding author
- Hussain, Malik A.
- Venue
- Food Reviews International
- Publisher
- Informa UK Limited
- Published
- 2014-11-26
- Volume
- 31
- Issue
- 1
- Pages
- 52-62
- ISSN
- 1525-6103 (ISSN-L)
- 8755-9129
- OpenAlex
- W2131778480
- Cited by
- 67
- References
- 41
- Citations by year
- 2026: 2 · 2025: 6 · 2024: 12 · 2023: 5 · 2022: 9 · 2021: 3 · 2020: 13 · 2019: 7 · 2017: 6 · 2016: 2 · 2015: 2
- FWCI
- 4.78
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Food Reviews International (publishedVersion)
- Lincoln University Research Archive (Lincoln University) (submittedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Antibiotic Resistance in Bacteria
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Bacterial Genetics and Biotechnology
- Keywords
- antibiotic resistance, probiotics, Lactobacillus, antibiotic resistance genes, horizontal gene transfer, antibiotic-associated diarrhea, gut microbiota
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