The DOI matches its Crossref record; 46 of the 46 references it cites were found in a registry or an index.
NDC10: a gene involved in chromosome segregation in Saccharomyces cerevisiae.
Open accessAbstract
A mutant, ndc10-1, was isolated by anti-tubulin staining of temperature-sensitive mutant banks of budding yeast. ndc10-1 has a defect chromosome segregation since chromosomes remains at one pole of the anaphase spindle. This produces one polyploid cell and one aploid cell, each containing a spindle pole body (SPD. NDC10 was cloned and sequenced and is identical to CBF2 (Jiang, W., J. Lechnermn and J. Carbon. 1993. J. Cell Biol. 121:513) which is the 110-kD component of a centromere DNA binding complex (Lechner, J., and J. Carbon. 1991. Cell. 61:717-725). NDC10 is an essential gene. Antibodies to Ndc10p labeled the SPB region in nearly all the cells examined including nonmitotic cells. In some cells with short spindles which may be in metaphase, staining was also observed along the spindle. The staining pattern and the phenotype of ndc10-1 are consistent with Cbf2p/Ndc10p being a kinetochore protein, and provide in vivo evidence for its role in the attachment of chromosomes to the spindle.
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Metadata
- Authors
- Goh, P. Y., & Kilmartin, J. V.
- Venue
- The Journal of cell biology
- Publisher
- Rockefeller University Press
- Published
- 1993-05-01
- Volume
- 121
- Issue
- 3
- Pages
- 503-512
- ISSN
- 0021-9525 (ISSN-L)
- 1540-8140
- OpenAlex
- W2111387496
- Cited by
- 264
- References
- 46
- Type
- conference abstract
- Language
- en
- Open access
- green
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- Goh, P. Y., & Kilmartin, J. V. (1993). NDC10: a gene involved in chromosome segregation in Saccharomyces cerevisiae. The Journal of cell biology. https://doi.org/10.1083/jcb.121.3.503
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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