Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor

Kato, Masaki, Patel, Millan S., Levasseur, Regis, Lobov, Ivan, Chang, Benny H.-J., Glass, Donald A., Hartmann, Christine, Li, Lan +5 more·2002·The Journal of Cell Biology

Cited by (999)

Items 201–300 of 999

  1. Wnt signaling in eye organogenesis
    Sabine Fuhrmann · 2008 · Organogenesis
  2. Skeletal defects inringelschwanzmutant mice reveal that Lrp6 is required for proper somitogenesis and osteogenesis
    Chikara Kokubu, U. Heinzmann, Tomoko Kokubu, Norio Sakai, Takuo Kubota, Masanobu Kawai, Matthias B. Wahl, Joan Galcerán, Rudolf Grosschedl, Keiichi Ozono et al. · 2004 · Development
  3. Bone mass is inversely proportional to Dkk1 levels in mice
    Bryan T. MacDonald, Danese M. Joiner, Sivan M. Oyserman, Parul Sharma, Steven A. Goldstein, Xi He, Peter V. Hauschka · 2007 · Bone
  4. Dkk1-induced inhibition of Wnt signaling in osteoblast differentiation is an underlying mechanism of bone loss in multiple myeloma
    Ya‐Wei Qiang, Bart Barlogie, Stuart Rudikoff, John D. Shaughnessy · 2007 · Bone
  5. Discoveries, drugs and skeletal disorders
    David Goltzman · 2002 · Nature Reviews Drug Discovery
  6. Osteotropic cancers: From primary tumor to bone
    Jeroen T. Buijs, Gabri van der Pluijm · 2008 · Cancer Letters
  7. Noncanonical Wnt5a enhances Wnt/β-catenin signaling during osteoblastogenesis
    Masanori Okamoto, Nobuyuki Udagawa, Shunsuke Uehara, Kazuhiro Maeda, Teruhito Yamashita, Yuko Nakamichi, Hiroyuki Kato, Naoto Saito, Yasuhiro Minami, Naoyuki Takahashi et al. · 2014 · Scientific Reports
  8. Gene array analysis of Wnt-regulated genes in C3H10T1/2 cells
    Amanda M. Jackson, Béatrice Vayssière, Teresa Garcia, William Newell, Roland Baron, Sergio Roman‐Roman, Georges Rawadi · 2005 · Bone
  9. Wnt10b deficiency results in age-dependent loss of bone mass and progressive reduction of mesenchymal progenitor cells
    Jennifer R Stevens, Gustavo A. Miranda‐Carboni, Meredith A. Singer, Sean M. Brugger, Karen M. Lyons, Timothy F. Lane · 2010 · Journal of Bone and Mineral Research
  10. Lactoferrin - A Novel Bone Growth Factor
    Dorit Naot, Angus C. Grey, Ian R. Reid, Jill Cornish · 2005 · Clinical Medicine & Research
  11. Glucocorticoids Inhibit the Transcriptional Activity of LEF/TCF in Differentiating Osteoblasts in a Glycogen Synthase Kinase-3β-dependent and -independent Manner
    Elisheva Smith, Baruch Frenkel · 2004 · Journal of Biological Chemistry
  12. The LRP5 High-Bone-Mass G171V Mutation Disrupts LRP5 Interaction with Mesd
    Yazhou Zhang, Yang Wang, Xiaofeng Li, Jianhong Zhang, Junhao Mao, Zhong Li, Jie Zheng, Lin Li, Steve Harris, Dianqing Wu · 2004 · Molecular and Cellular Biology
  13. Osteocyte morphology in human tibiae of different bone pathologies with different bone mineral density — Is there a role for mechanosensing?
    Ruud P. van Hove, Peter A. Nolte, Aviral Vatsa, Cor M. Semeins, Philip L. Salmon, Theo H. Smit, Jenneke Klein‐Nulend · 2009 · Bone
  14. Increasing Wnt signaling in the bone marrow microenvironment inhibits the development of myeloma bone disease and reduces tumor burden in bone in vivo
    Claire M. Edwards, James Edwards, Seint T. Lwin, Javier M. Esparza, Babatunde O. Oyajobi, Brandon McCluskey, Steve A. Munoz, Barry G. Grubbs, Gregory R. Mundy · 2007 · Blood
  15. Minireview: Transcriptional Regulation in Development of Bone
    Tatsuya Kobayashi, Henry M. Kronenberg · 2004 · Endocrinology
  16. Osteoblasts Directly Control Lineage Commitment of Mesenchymal Progenitor Cells through Wnt Signaling
    Hong Zhou, Wendy Mak, Yu Zheng, Colin Robert Dunstan, Markus J. Seibel · 2007 · Journal of Biological Chemistry
  17. Inhibition of Wnt signaling by the osteoblast-specific transcription factor Osterix
    Chi Zhang, Kyucheol Cho, Ye-Hong Huang, Jon P. Lyons, Xin Zhou, Krishna Murari Sinha, Pierre D. McCrea, Benoît De Crombrugghe · 2008 · Proceedings of the National Academy of Sciences
  18. The Orphan Receptor Tyrosine Kinase Ror2 Modulates Canonical Wnt Signaling in Osteoblastic Cells
    Julia Billiard, Deana S. Way, Laura Seestaller‐Wehr, Robert A. Moran, Annamarie Mangine, Peter V.N. Bodine · 2004 · Molecular Endocrinology
  19. Bone biomechanical properties in LRP5 mutant mice
    M. P. Akhter, D.J. Wells, S.J. Short, Diane M. Cullen, Mark L. Johnson, Gleb R. Haynatzki, Philip Babij, Kristina M. Allen, Paul J. Yaworsky, Frederick J. Bex et al. · 2004 · Bone
  20. Origin matters: Differences in embryonic tissue origin and Wnt signaling determine the osteogenic potential and healing capacity of frontal and parietal calvarial bones
    Natalina Quarto, Derrick C. Wan, Matthew D. Kwan, Nicholas John Panetta, Shuli Li, Michael Thornton Longaker · 2009 · Journal of Bone and Mineral Research
  21. Modulation of canonical Wnt signaling by the extracellular matrix component biglycan
    Agnes D. Berendsen, Larry W. Fisher, Tina M. Kilts, Rick T. Owens, Pamela Gehron Robey, Jorge Silvio Gutkind, Marian F. Young · 2011 · Proceedings of the National Academy of Sciences
  22. Role of the Norrie Disease Pseudoglioma Gene in Sprouting Angiogenesis during Development of the Retinal Vasculature
    Ulrich F. O. Luhmann, Jihong Lin, Niyazi Acar, Stefanie Lammel, Silke Feil, Christian Grimm, Mathias W. Seeliger, Hans‐Peter Hammes, Wolfgang Berger · 2005 · Investigative Ophthalmology & Visual Science
  23. Wnt signaling and skeletal development
    Fei Liu, Sean E. Kohlmeier, Cun-Yu Wang · 2007 · Cellular Signalling
  24. Serum concentrations of Dickkopf‐1 protein are increased in patients with multiple myeloma and reduced after autologous stem cell transplantation
    Marianna Politou, Deborah J. Heath, Amin Rahemtulla, Richard Szydlo, Athanasios Anagnostopoulos, Meletios Athanasios Dimopoulos, Peter Ian Croucher, Evangelos Terpos · 2006 · International Journal of Cancer
  25. Animal models of ocular angiogenesis: from development to pathologies
    Chi‐Hsiu Liu, Zhongxiao Wang, Ye Sun, Jing Chen · 2017 · The FASEB Journal
  26. GSK-3β Controls Osteogenesis through Regulating Runx2 Activity
    Fumitaka Kugimiya, Hiroshi Kawaguchi, Shinsuke Ohba, Naohiro Kawamura, Makoto Hirata, Hirotaka Chikuda, Yoshiaki Azuma, James Robert Woodgett, Kozo Nakamura, Ung‐il Chung · 2007 · PLoS ONE
  27. Gene-Environment Interactions in the Skeletal Response to Nutrition and Exercise during Growth
    Jean‐Philippe Bonjour, Thierry Chevalley, René Rizzoli, Serge Ferrari · 2007 · KARGER eBooks
  28. Increased glutamine catabolism mediates bone anabolism in response to WNT signaling
    Courtney M. Karner, Emel Esen, Adewole L. Okunade, Bruce W. Patterson, Fanxin Long · 2014 · Journal of Clinical Investigation
  29. Phase Ib clinical trial of the anti-frizzled antibody vantictumab (OMP-18R5) plus paclitaxel in patients with locally advanced or metastatic HER2-negative breast cancer
    Jennifer Robinson Diamond, Carlos Becerra, Donald Richards, Alain C. Mita, Cynthia R. C. Osborne, Joyce O’Shaughnessy, Chun Zhang, Randall Henner, Ann M. Kapoun, Lu Xu et al. · 2020 · Breast Cancer Research and Treatment
  30. Roles of Wnt signalling in bone growth, remodelling, skeletal disorders and fracture repair
    Carmen E. Macsai, Bruce K. Foster, Cory J. Xian · 2008 · Journal of Cellular Physiology
  31. Osx transcriptional regulation is mediated by additional pathways to BMP2/Smad signaling
    Ayse B. Celil, Jeffrey O. Hollinger, Phil G. Campbell · 2005 · Journal of Cellular Biochemistry
  32. Overview of the mutation spectrum in familial exudative vitreoretinopathy and Norrie disease with identification of 21 novel variants in FZD4, LRP5, and NDP
    Konstantinos Nikopoulos, Hanka Venselaar, Rob W.J. Collin, Rosa Riveiro-Álvarez, F. Nienke Boonstra, Johanna M. M. Hooymans, Arijit Mukhopadhyay, Deborah J. Shears, Marleen van Bers, Ilse J. de Wijs et al. · 2010 · Human Mutation
  33. The Role of RUNX2 in Osteosarcoma Oncogenesis
    Jeff W. Martin, Maria Zieleńska, Gary S. Stein, André J. van Wijnen, Jeremy Andrew Squire · 2010 · Sarcoma
  34. Downregulation of Wnt Signaling by Increased Expression of Dickkopf-1 and -2 is a Prerequisite for Late-Stage Osteoblast Differentiation of KS483 Cells
    Geertje van der Horst, Steffie Maria van der Werf, Hetty C. M. Farih-Sips, Rutger Leo van Bezooijen, Clemens W.G.M. Löwik, Marcel Karperien · 2005 · Journal of Bone and Mineral Research
  35. Wnt/frizzled signaling in hepatocellular carcinoma
    Han Chu Lee · 2006 · Frontiers in bioscience
  36. Common Genetic Variation of the Low-Density Lipoprotein Receptor-Related Protein 5 and 6 Genes Determines Fracture Risk in Elderly White Men
    Joyce B. J. van Meurs, Fernando Rivadeneira, Mila M. Jhamai, Wendy Hugens, Albert Hofman D, Johannes P.T.M. van Leeuwen, Huibert A. P. Pols, André Gerardus Uitterlinden · 2006 · Journal of Bone and Mineral Research
  37. The duality of β-catenin function: A requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm
    April N. Smith, Leigh‐Anne D. Miller, Ni Song, Makoto Mark Taketo, Richard A. Lang · 2005 · Developmental Biology
  38. Lrp5 and Lrp6 redundantly control skeletal development in the mouse embryo
    Kyu Sang Joeng, Cassie A. Schumacher, Cassandra R. Diegel, Fanxin Long, Bart O. Williams · 2011 · Developmental Biology
  39. N-Cadherin Interacts with Axin and LRP5 To Negatively Regulate Wnt/β-Catenin Signaling, Osteoblast Function, and Bone Formation
    Eric Haÿ, Emmanuel Laplantine, Valérie Geoffroy, Monique Frain, Thomas Kohler, Ralph Müller, Pierre J. Marie · 2008 · Molecular and Cellular Biology
  40. The roles of exercise in bone remodeling and in prevention and treatment of osteoporosis
    Yu Jing Yuan, Xi Chen, Lingli Zhang, Juanni Wu, Jianming Guo, Dongchen Zou, Binglin Chen, Zhongguang Sun, Chao Shen, Jun Zou · 2015 · Progress in Biophysics and Molecular Biology
  41. Association between bone mineral densities and serum lipid profiles of pre- and post-menopausal rural women in South Korea
    Lianhua Cui, Min‐Ho Shin, Eun‐Kyung Chung, Young Hoon Lee, Sun‐Seog Kweon, Kyeong-Soo Park, Jin‐Su Choi · 2005 · Osteoporosis International
  42. Cross-talk between Wnt and Bone Morphogenetic Protein 2 (BMP-2) Signaling in Differentiation Pathway of C2C12 Myoblasts
    Aiko Nakashima, Takenobu Katagiri, Masato Tamura · 2005 · Journal of Biological Chemistry
  43. Regulation of Wnt/β-catenin signaling within and from osteocytes
    Travis Burgers, Bart O. Williams · 2013 · Bone
  44. Osteoporosis and atherosclerosis: biological linkages and the emergence of dual-purpose therapies
    David Hamerman · 2005 · QJM
  45. WNT7B Promotes Bone Formation in part through mTORC1
    Jianquan Chen, Xiaolin Tu, Emel Esen, Kyu Sang Joeng, Congxin Lin, Jeffrey M. Arbeit, Markus A. Rüegg, Michael N. Hall, Liang Ma, Fanxin Long · 2014 · PLoS Genetics
  46. Longevity and Lineages: Toward the Integrative Biology of Degenerative Diseases in Heart, Muscle, and Bone
    Kenneth R. Chien, Gérard Karsenty · 2005 · Cell
  47. Functional Characterization of WNT7A Signaling in PC12 Cells
    Andrea Caricasole, Teresa Ferraro, Luisa Iacovelli, Eliana Barletta, Alessandra Caruso, Daniela Melchiorri, Georg C. Terstappen, Ferdinando Nicoletti · 2003 · Journal of Biological Chemistry
  48. Differentiation of the brain vasculature: the answer came blowing by the Wnt
    Stefan Liebner, Karl Heinz Plate · 2010 · Vascular Cell
  49. Secreted Frizzled-Related Protein-1 Inhibits RANKL-Dependent Osteoclast Formation
    K D Hausler, Nicole J. Horwood, Yoshiro Chuman, Jane Fisher, Jennifer Ellis, Thomas John Martin, Jeffrey S. Rubin, Matthew T. Gillespie · 2004 · Journal of Bone and Mineral Research
  50. Wnt signaling in heart valve development and osteogenic gene induction
    Alfieri, Christina M., Cheek, Jonathan, Chakraborty, Santanu, Yutzey, Katherine E. · 2010 · Developmental Biology
  51. The Wnt signaling pathway and bone metabolism
    Mark L. Johnson, Mohamed A. Kamel · 2007 · Current Opinion in Rheumatology
  52. Is obesity in women protective against osteoporosis?
    Silvia Migliaccio, Emanuela Alessandra Greco, F Fornari, Lorenzo M. Donini, Lenzi · 2011 · Diabetes Metabolic Syndrome and Obesity
  53. The Bone Organ System
    Cassandra Alda Lee, Thomas A. Einhorn · 2001 · Elsevier eBooks
  54. Persistent hyperplastic primary vitreous: congenital malformation of the eye
    Barkur S. Shastry · 2009 · Clinical and Experimental Ophthalmology
  55. Wnt signaling inhibits cementoblast differentiation and promotes proliferation
    Eiji Nemoto, 洋平 越川, Sousuke Kanaya, Masahiro Tsuchiya, Masato Tamura, Martha Joan Somerman, Hidetoshi Shimauchi · 2009 · Bone
  56. A Novel Mechanism for Wnt Activation of Canonical Signaling through the LRP6 Receptor
    Guizhong Liu, Anna Bafico, Violaine Harris, Stuart A. Aaronson · 2003 · Molecular and Cellular Biology
  57. Vitamin D and Wnt/beta-catenin pathway in colon cancer: role and regulation of DICKKOPF genes.
    Natalia Pendás-Franco, Oscar Aguilera, Fábio Pereira, José Manuel González‐Sancho, Alberto Múñoz · 2008 · PubMed
  58. Loci for regulation of bone mineral density in men and women identified by genome wide linkage scan: the FAMOS study
    Stuart H. Ralston, Nick W. Galwey, Ian Mackay, Omar Albagha, Lon R. Cardon, Juliet Elizabeth Compston, Cyrus C. Cooper, Emma L. Duncan, Richard W. Keen, Bente Lomholt Langdahl et al. · 2005 · Human Molecular Genetics
  59. Wnt signaling in bone and muscle
    Rudnicki, Michael A., Williams, Bart O. · 2015 · Bone
  60. The Wnt/β-Catenin Signaling Pathway as a Target in Drug Discovery
    Fumi Takahashi‐Yanaga, Toshiyuki Sasaguri · 2007 · Journal of Pharmacological Sciences
  61. A Comprehensive Overview of Skeletal Phenotypes Associated with Alterations in Wnt/β-catenin Signaling in Humans and Mice
    Kevin A. Maupin, Casey J. Droscha, Bart O. Williams · 2013 · Bone Research
  62. Molecular Bases of the Regulation of Bone Remodeling by the Canonical Wnt Signaling Pathway
    Donald A. Glass, Gérard Karsenty · 2006 · Current topics in developmental biology/Current Topics in Developmental Biology
  63. Wnt Signaling Mediates Pathological Vascular Growth in Proliferative Retinopathy
    Jing Chen, Andreas Stahl, Nathan M. Krah, Molly R. Seaward, Roberta J. Dennison, Przemyslaw S. Sapieha, Jing Hua, Colman J. Hatton, Aimee M. Juan, Christopher M. Aderman et al. · 2011 · Circulation
  64. A role for Wnt/β-catenin signaling in lens epithelial differentiation
    Richard J.W. Stump, Sharyn L. Ang, Yongjuan Chen, Tatiana von Bahr, Frank James Lovicu, Kathleen I. Pinson, Robb U. de Iongh, Terry P. Yamaguchi, David A. Sassoon, John W. McAvoy · 2003 · Developmental Biology
  65. Severe Hypercholesterolemia, Impaired Fat Tolerance, and Advanced Atherosclerosis in Mice Lacking Both Low Density Lipoprotein Receptor-related Protein 5 and Apolipoprotein E
    Kenta Magoori, Man‐Jong Kang, Mitsuko R. Ito, Hajime Kakuuchi, Ryoichi X. Ioka, Akihisa Kamataki, Dong-Ho Kim, Hiroshi Asaba, Satoshi Iwasaki, Yumiko A. Takei et al. · 2003 · Journal of Biological Chemistry
  66. β-catenin promotes bone formation and suppresses bone resorption in postnatal growing mice
    Jianquan Chen, Fanxin Long · 2012 · Journal of Bone and Mineral Research
  67. Osteoblast-Targeted Expression of Sfrp4 in Mice Results in Low Bone Mass
    Rika Nakanishi, Haruhiko Akiyama, Hiroaki J. Kimura, Bungo Otsuki, Motoyuki Shimizu, Tadao Tsuboyama, Takashi Nakamura · 2007 · Journal of Bone and Mineral Research
  68. Wnt signaling activation during bone regeneration and the role of Dishevelled in chondrocyte proliferation and differentiation
    Nan Zhong, Robert P. Gersch, Michael Hadjiargyrou · 2006 · Bone
  69. Diseases of Wnt signaling
    Mark L. Johnson, Nalini Marie Rajamannan · 2006 · Reviews in Endocrine and Metabolic Disorders
  70. Overexpression of MiR-335-5p Promotes Bone Formation and Regeneration in Mice
    Lan Zhang, Yin Tang, Xiaofang Zhu, Tianchi Tu, Lei Sui, Qianqian Han, Liming Yu, Shu Meng, Leilei Zheng, Paloma Valverde et al. · 2017 · Journal of Bone and Mineral Research
  71. Wnt signaling and the regulation of bone mass
    Roland Baron, Georges Rawadi · 2007 · Current Osteoporosis Reports
  72. SMAD4-mediated WNT signaling controls the fate of cranial neural crest cells during tooth morphogenesis
    Jingyuan Li, Xiaofeng Huang, Xun Xu, Julie Mayo, Pablo Bringas, Rulang Jiang, Songling Wang, Yang Chai · 2011 · Development
  73. The Wnt Receptor, Lrp5, Is Expressed by Mouse Mammary Stem Cells and Is Required to Maintain the Basal Lineage
    Nisha M. Badders, Shruti Goel, Rod J. Clark, Kristine S. Klos, So Young Kim, Anna Bafico, Charlotta J. Lindvall, Bart O. Williams, Caroline M. Alexander · 2009 · PLoS ONE
  74. Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan
    Tao-Hsin Chang, Fu-Lien Hsieh, Matthias Zebisch, Karl Harlos, Jonathan Elegheert, E. Yvonne Jones · 2015 · eLife
  75. WNT signaling in bone development and homeostasis
    Zhendong A. Zhong, Nicole J. Ethen, Bart O. Williams · 2014 · Wiley Interdisciplinary Reviews Developmental Biology
  76. Osteoblastogenesis regulation signals in bone remodeling
    Chijian Zuo, Yu‐Ting Huang, R. Bajis, M. Sahih, Yining Li, Kerong Dai, Xiaoling Zhang · 2012 · Osteoporosis International
  77. R-spondin-2 is a Wnt agonist that regulates osteoblast activity and bone mass
    M. Noelle Knight, Kannan Karuppaiah, Michele Lowe, Sarthak Mohanty, Robert L. Zondervan, Sheila M. Bell, Jaimo Ahn, Kurt David Hankenson · 2018 · Bone Research
  78. Secreted Frizzled-Related Protein 1 Modulates Glucocorticoid Attenuation of Osteogenic Activities and Bone Mass
    Feng‐Sheng Wang, Chun‐Liang Lin, Yeung-Jen Chen, Ching‐Jen Wang, Kuender D. Yang, Yu‐Ting Huang, Yi‐Chih Sun, Hui-Chen Huang · 2005 · Endocrinology
  79. Vascular morphogenesis: a Wnt for every vessel?
    Claudio Areias Franco, Stefan Liebner, Holger Gerhardt · 2009 · Current Opinion in Genetics & Development
  80. Wnt signaling: A win for bone
    Elke Piters, Eveline Boudin, Wim Van Hul · 2008 · Archives of Biochemistry and Biophysics
  81. Evidence for a bone-kidney axis regulating phosphate homeostasis
    L. Darryl Quarles · 2003 · Journal of Clinical Investigation
  82. Advances in Defining Regulators of Cementum Development and Periodontal Regeneration
    Brian Lee Foster, Tracy E. Popowics, Hanson K. Fong, Martha Joan Somerman · 2007 · Current topics in developmental biology/Current Topics in Developmental Biology
  83. Hypomorphic expression ofDkk1in thedoubleridgemouse: dose dependence and compensatory interactions withLrp6
    Bryan T. MacDonald, Maja Adamska, Miriam H. Meisler · 2004 · Development
  84. Is Wnt signalling the final common pathway leading to bone formation?
    Frances Milat, Kong Wah Ng · 2009 · Molecular and Cellular Endocrinology
  85. Fibroblast Growth Factor 2 Stimulation of Osteoblast Differentiation and Bone Formation Is Mediated by Modulation of the Wnt Signaling Pathway
    Yurong Fei, Liping Xiao, Thomas Doetschman, Douglas J. Coffin, Marja M. Hurley · 2011 · Journal of Biological Chemistry
  86. Epidermal Growth Factor Receptor-deficient Mice Have Delayed Primary Endochondral Ossification Because of Defective Osteoclast Recruitment
    Ke Wang, Hiroaki Yamamoto, Jennie R. Chin, Zena Werb, Thiennu H. Vu · 2004 · Journal of Biological Chemistry
  87. Genetic mouse models for bone studies—Strengths and limitations
    Florent Elefteriou, Xiangli Yang · 2011 · Bone
  88. Targeting myostatin/activin A protects against skeletal muscle and bone loss during spaceflight
    Lee, Se-Jin, Lehar, Adam, Meir, Jessica U., Koch, Christina, Morgan, Andrew, Warren, Lara E., Rydzik, Renata, Youngstrom, Daniel W., Chandok, Harshpreet, George, Joshy et al. · 2020 · Proceedings of the National Academy of Sciences
  89. Deletion of a Single β-Catenin Allele in Osteocytes Abolishes the Bone Anabolic Response to Loading
    Behzâd Javaheri, Amber Rath Stern, Nuria Lara, Mark Dallas, Hong Liang Zhao, Ying Liu, Lynda Faye Bonewald, Mark L. Johnson · 2013 · Journal of Bone and Mineral Research
  90. Mutational Analysis of Norrin-Frizzled4 Recognition
    Philip M. Smallwood, John Williams, Qiang Xu, Daniel J. Leahy, Jeremy Nathans · 2006 · Journal of Biological Chemistry
  91. Effects of intermittent parathyroid hormone (PTH) administration on SOST mRNA and protein in rat bone
    G. Silvestrini, Paola Ballanti, Martina Leopizzi, Mariangela Sebastiani, Silvia Berni, Maura Di Vito, ERMANNO BONUCCI · 2007 · Journal of Molecular Histology
  92. Cell-to-cell interactions in bone
    Joseph P. Stains, Roberto Civitelli · 2004 · Biochemical and Biophysical Research Communications
  93. Modulation of Wnt signaling influences fracture repair
    David E. Komatsu, Michelle N. Mary, Robert Jason Schroeder, Alex G. Robling, Charles H. Turner, Stuart J. Warden · 2010 · Journal of Orthopaedic Research®
  94. Roles of Wnt signals in bone resorption during physiological and pathological states
    Kazuhiro Maeda, Naoyuki Takahashi, Yasuhiro Kobayashi · 2012 · Journal of Molecular Medicine
  95. Osteoimmunology: cytokines and the skeletal system
    Seoung‐Hoon Lee, Tae Soo Kim, Yongwon Choi, Joseph Lorenzo · 2008 · BMB Reports
  96. Cannabidiol, a Major Non-Psychotropic Cannabis Constituent Enhances Fracture Healing and Stimulates Lysyl Hydroxylase Activity in Osteoblasts
    Natalya M. Kogan, Eitan Melamed, Elad Wasserman, Bitya Raphael-Mizrahi, Aviva Breuer, Kathryn S. Stok, Rachel E. Sondergaard, Ana V. Villarreal Escudero, Saja Baraghithy, Malka Attar-Namdar et al. · 2015 · Journal of Bone and Mineral Research
  97. THE IMMUNE SYSTEM AND BONE
    R. Pacifici · 2010 · Archives of Biochemistry and Biophysics
  98. Lrp5 and Lrp6 Exert Overlapping Functions in Osteoblasts during Postnatal Bone Acquisition
    Ryan C. Riddle, Cassandra R. Diegel, Julie M. Leslie, Kyle van Koevering, Marie‐Claude Monier‐Faugere, Thomas L. Clemens, Bart O. Williams · 2013 · PLoS ONE
  99. Parathyroid Hormone Increases β-Catenin Levels through Smad3 in Mouse Osteoblastic Cells
    Takako Tobimatsu, Hiroshi Kaji, Hideaki Sowa, Junko Naito, Lucie Canaff, Geoffrey N. Hendy, Toshitsugu Sugimoto, Kazuo Chihara · 2006 · Endocrinology
  100. Genetic variation at the low-density lipoprotein receptor-related protein 5 (LRP5) locus modulates Wnt signaling and the relationship of physical activity with bone mineral density in men
    Douglas P. Kiel, Serge Ferrari, L. Adrienne Cupples, David Karasik, Danielle Manen, Alma Imamović, Alan G. Herbert, Josée Dupuis · 2006 · Bone