The DOI matches its Crossref record; 54 of the 54 references it cites were found in a registry or an index.
Proximal location of mouse prostate epithelial stem cells
Open accessAbstract
Stem cells are believed to regulate normal prostatic homeostasis and to play a role in the etiology of prostate cancer and benign prostatic hyperplasia. We show here that the proximal region of mouse prostatic ducts is enriched in a subpopulation of epithelial cells that exhibit three important attributes of epithelial stem cells: they are slow cycling, possess a high in vitro proliferative potential, and can reconstitute highly branched glandular ductal structures in collagen gels. We propose a model of prostatic homeostasis in which mouse prostatic epithelial stem cells are concentrated in the proximal region of prostatic ducts while the transit-amplifying cells occupy the distal region of the ducts. This model can account for many biological differences between cells of the proximal and distal regions, and has implications for prostatic disease formation.
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Cites
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Cited by
CD133, a novel marker for human prostatic epithelial stem cells
Richardson, G. D., Robson, C. N., Lang, S. H., Neal, D. E., Maitland, N. J., & Collins, A. T. (2004) · Journal of Cell Science · doi:10.1242/jcs.01222 · Cited by 770
A luminal epithelial stem cell that is a cell of origin for prostate cancer
Wang, X., Julio, M. K.-D., Economides, K. D., Walker, D., Yu, H., Halili, M. V., Hu, Y.-P., Price, S. M., Abate-Shen, C., & Shen, M. M. (2009) · Nature · doi:10.1038/nature08361 · Cited by 734
Uterine stem cells: What is the evidence?
Gargett, C. E. (2007) · Human Reproduction Update · doi:10.1093/humupd/dml045 · Cited by 373
A Cellular Anatomy of the Normal Adult Human Prostate and Prostatic Urethra
Henry, G. H., Malewska, A., Joseph, D. B., Malladi, V. S., Lee, J., Torrealba, J., Mauck, R. J., Gahan, J. C., Raj, G. V., Roehrborn, C. G., et al. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.11.086 · Cited by 355
Basal epithelial stem cells are efficient targets for prostate cancer initiation
Lawson, D. A., Zong, Y., Memarzadeh, S., Xin, L., Huang, J., & Witte, O. N. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0913873107 · Cited by 275
Metadata
- Authors
- Tsujimura, A., Koikawa, Y., Salm, S., Takao, T., Coetzee, S., Moscatelli, D., Shapiro, E., Lepor, H., Sun, T.-T., & Wilson, E. L.
- Venue
- The Journal of Cell Biology
- Publisher
- Rockefeller University Press
- Published
- 2002-06-24
- Volume
- 157
- Issue
- 7
- Pages
- 1257-1265
- ISSN
- 0021-9525 (ISSN-L)
- 1540-8140
- OpenAlex
- W2167198420
- Cited by
- 305
- References
- 54
- FWCI
- 6.78
- Type
- journal article
- Language
- en
- Open access
- green
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- Tsujimura, A., Koikawa, Y., Salm, S., Takao, T., Coetzee, S., Moscatelli, D., Shapiro, E., Lepor, H., Sun, T.-T., & Wilson, E. L. (2002). Proximal location of mouse prostate epithelial stem cells. The Journal of Cell Biology. https://doi.org/10.1083/jcb.200202067
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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