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HUMAN IMMUNITY TO THE MENINGOCOCCUS
Open accessAbstract
High molecular weight group A and group C meningococcal polysaccharides had no significant toxicity for mice or guinea pigs. Furthermore, these polysaccharide preparations contained negligible amounts of biologically active endotoxin. The high molecular weight group A and group C meningococcal polysaccharides were excellent immunogens in six human volunteers. Antibodies belonging to the immunoglobulin classes IgG, IgM, and IgA were produced. These antibodies were highly meningococcocidal in the presence of complement.
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Citations
Cited by
Epidemic meningitis, meningococcaemia, and Neisseria meningitidis
Stephens, D. S., Greenwood, B., & Brandtzaeg, P. (2007) · The Lancet · doi:10.1016/s0140-6736(07)61016-2 · Cited by 978
Vaccination against Neisseria meningitidis Using Three Variants of the Lipoprotein GNA1870
Masignani, V., Comanducci, M., Giuliani, M. M., Bambini, S., Adu-Bobie, J., Aricò, B., Brunelli, B., Pieri, A., Santini, L., Savino, S., et al. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20021911 · Cited by 395
Meningococcal meningitis in Africa
Greenwood, B. (1999) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1016/s0035-9203(99)90106-2 · Cited by 358
NadA, a Novel Vaccine Candidate of Neisseria meningitidis
Comanducci, M., Bambini, S., Brunelli, B., Adu-Bobie, J., Aricò, B., Capecchi, B., Giuliani, M. M., Masignani, V., Santini, L., Savino, S., et al. (2002) · The Journal of Experimental Medicine · doi:10.1084/jem.20020407 · Cited by 351
Kulkarni, P. S., Hurwitz, J. L., Simões, E. A. F., & Piedra, P. A. (2018) · Viral Immunology · doi:10.1089/vim.2017.0147 · Cited by 53
Metadata
- Authors
- Gotschlich, E. C., Goldschneider, I., & Artenstein, M. S.
- Venue
- The Journal of Experimental Medicine
- Publisher
- Rockefeller University Press
- Published
- 1969-06-01
- Volume
- 129
- Issue
- 6
- Pages
- 1367-1384
- ISSN
- 0022-1007 (ISSN-L)
- 1540-9538
- OpenAlex
- W2155610175
- Cited by
- 402
- References
- 0
- FWCI
- 26.56
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: HUMAN IMMUNITY TO THE MENINGOCOCCUS. https://app.cochat.ai/papers/10.1084/jem.129.6.1367
- The paper
- Gotschlich, E. C., Goldschneider, I., & Artenstein, M. S. (1969). HUMAN IMMUNITY TO THE MENINGOCOCCUS. The Journal of Experimental Medicine. https://doi.org/10.1084/jem.129.6.1367
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
