The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
NK3-specific natural killer cells are selectively inhibited by Bw4-positive HLA alleles with isoleucine 80.
Open accessAbstract
Natural killer (NK) cell clones have been previously described which are inhibited by HLA-C alleles with Asn77-Lys80 (NK1-specific cells) or by HLA-C alleles with Ser77-Asn80 (NK2-specific cells). In the present work, the generation of NK cells with HLA-B-related specificities was attempted by stimulation of a Bw4 homozygous responder by a Bw6 homozygous donor. Two NK clones were found, which were inhibited by HLA-Bw4 (but not by HLA-Bw6) allotypes and by some HLA-A allotypes that share the Bw4 public epitope. Inhibition of NK cell-mediated lysis strongly correlated with the presence of an Ile residue at position 80 of the protective allele. These NK cell clones define a new specificity termed NK3.
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Cites
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Self-citationNKR-P1, a Signal Transduction Molecule on Natural Killer Cells
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Cited by
Lanier, L. L. (1998) · Annual Review of Immunology · doi:10.1146/annurev.immunol.16.1.359 · Cited by 1,648
MHC class I molecules and kirs in human history, health and survival
Parham, P. (2005) · Nature Reviews Immunology · doi:10.1038/nri1570 · Cited by 1,203
KIR: Diverse, Rapidly Evolving Receptors of Innate and Adaptive Immunity
Vilches, C., & Parham, P. (2002) · Annual Review of Immunology · doi:10.1146/annurev.immunol.20.092501.134942 · Cited by 986
Colonna, M., & Samaridis, J. (1995) · Science · doi:10.1126/science.7716543 · Cited by 736
Self-citationProspects for the use of NK cells in immunotherapy of human cancer
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Metadata
- Authors
- Cella, M., Longo, A., Ferrara, G. B., Strominger, J. L., & Colonna, M.
- Venue
- The Journal of experimental medicine
- Publisher
- Rockefeller University Press
- Published
- 1994-10-01
- Volume
- 180
- Issue
- 4
- Pages
- 1235-1242
- ISSN
- 0022-1007 (ISSN-L)
- 1540-9538
- OpenAlex
- W1968046203
- Cited by
- 340
- References
- 23
- FWCI
- 5.88
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Cella, M., Longo, A., Ferrara, G. B., Strominger, J. L., & Colonna, M. (1994). NK3-specific natural killer cells are selectively inhibited by Bw4-positive HLA alleles with isoleucine 80. The Journal of experimental medicine. https://doi.org/10.1084/jem.180.4.1235
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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