PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps

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Neutrophil Extracellular Traps Kill Bacteria

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Translating the Histone Code

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Novel cell death program leads to neutrophil extracellular traps

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Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation

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Human PAD4 Regulates Histone Arginine Methylation Levels via Demethylimination

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Xuanfei Baidu Decoction regulates NETs formation via CXCL2/CXCR2 signaling pathway that is involved in acute lung injury

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Peptidylarginine Deiminases as Drug Targets in Neonatal Hypoxic–Ischemic Encephalopathy

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Degradation of Extracellular DNA by DNase1 Significantly Reduces Testicular Damage After Testicular Torsion in Rats

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Pinniped- and Cetacean-Derived ETosis Contributes to Combating Emerging Apicomplexan Parasites (Toxoplasma gondii, Neospora caninum) Circulating in Marine Environments

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Group A Streptococcus establishes pharynx infection by degrading the deoxyribonucleic acid of neutrophil extracellular traps

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Citrullination regulates wound responses and tissue regeneration in zebrafish

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The impact of neutrophil extracellular traps on deep venous thrombosis in patients with traumatic fractures

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Neutrophil extracellular traps: new aspects

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Neutrophils in autoimmunity: when the hero becomes the villain

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Neutrophil degranulation and severely impaired extracellular trap formation at the basis of susceptibility to infections of hemodialysis patients

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Inhibition of Netosis with PAD Inhibitor Attenuates Endotoxin Shock Induced Systemic Inflammation

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Neutrophil extracellular traps and complications of liver transplantation

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Mycobacterium tuberculosis in a Trap: The Role of Neutrophil Extracellular Traps in Tuberculosis

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Targeting Neutrophil α9 Improves Functional Outcomes After Stroke in Mice With Obesity-Induced Hyperglycemia

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The NET , the trap and the pathogen: neutrophil extracellular traps in cutaneous immunity

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Neutrophil extracellular traps are critical for pregnancy loss in sphingosine kinase–deficient mice on 129Sv/C57BL/6 background

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NETs detection and quantification in paraffin embedded samples using confocal microscopy

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Peptidylarginine Deiminase 4 Promotes the Renal Infiltration of Neutrophils and Exacerbates the TLR7 Agonist-Induced Lupus Mice

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Neutrophil Extracellular Traps in Coronavirus Disease-19-Associated Ischemic Stroke: A Novel Avenue in Neuroscience

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Insights into the role of neutrophils in neuropsychiatric systemic lupus erythematosus: Current understanding and future directions

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Inhibition of NETosis via PAD4 alleviated inflammation in giant cell myocarditis

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Proteomics of citrullination in cardiovascular disease

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Disentangling the role of neutrophil extracellular traps in rheumatic diseases

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Extracellular Sphingomyelinase Rv0888 of Mycobacterium tuberculosis Contributes to Pathological Lung Injury of Mycobacterium smegmatis in Mice via Inducing Formation of Neutrophil Extracellular Traps

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Regulation of neutrophil pro-inflammatory functions sheds new light on the pathogenesis of rheumatoid arthritis

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Peptidylarginine Deiminase IV Regulates Breast Cancer Stem Cells via a Novel Tumor Cell–Autonomous Suppressor Role

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Cardiovascular Diseases: Consider Netosis

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Facile Fluorescence‐Based Detection of PAD4‐Mediated Citrullination

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Flow cytometric quantification of neutrophil extracellular traps: Limitations of the methodological approach

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Neutrophil extracellular traps mediate neuro-immunothrombosis

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Classical monocyte ontogeny dictates their functions and fates as tissue macrophages

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Neutrophil extracellular traps protect the kidney from ascending infection and are required for a positive leukocyte dipstick test

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The dynamic roles of macrophages extracellular traps (METs) in immune regulation

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Deiminated proteins in extracellular vesicles and serum of llama (Lama glama)—Novel insights into camelid immunity

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Neutrophil Functional Heterogeneity and Implications for Viral Infections and Treatments

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Extracellular traps and the role in thrombosis

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Neutrophil Extracellular Traps (NETs) in Ocular Diseases: An Update

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Neutrophils Protect Against Staphylococcus aureus Endocarditis Progression Independent of Extracellular Trap Release

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Neutrophil Extracellular Traps and Their Possible Implications in Ocular Herpes Infection

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Epitope Specificity of Anti-Citrullinated Protein Antibodies

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Fatty and hydroxycarboxylic acid receptors: The missing link of immune response and metabolism in cattle

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Histoplasma capsulatum ‐induced extracellular DNA trap release in human neutrophils

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Increased IgA anti‐citrullinated protein antibodies in the periodontal inflammatory exudate of healthy individuals compared to rheumatoid arthritis patients

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The pivotal role of neutrophil extracellular traps in cardiovascular diseases: Mechanisms and therapeutic implications

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Disulfiram-loaded nanovesicles hydrogel promotes healing of diabetic wound

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Neutrophil Extracellular Traps (NETs) in Sterile Inflammatory Diseases

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Polymorphisms and functional haplotype in PADI4: Further evidence for contribution on rheumatoid arthritis susceptibility and anti-cyclic citrullinated peptide antibodies in a western Mexican population

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Clinical and immunological aspects of anti-peptidylarginine deiminase type 4 (anti-PAD4) autoantibodies in rheumatoid arthritis

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The NLRP3 Inflammasome: Relevance in Solid Organ Transplantation

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Neutrophils Contribute to ER Stress in Lung Epithelial Cells in the Pristane-Induced Diffuse Alveolar Hemorrhage Mouse Model

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Ginsenoside Rg5 allosterically interacts with P2RY12 and ameliorates deep venous thrombosis by counteracting neutrophil NETosis and inflammatory response

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iPAD or PADi — ‘tablets’ with therapeutic disease potential?

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Neutrophil Extracellular Traps in Atherosclerosis and Thrombosis

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Neutrophils in Streptococcus suis Infection: From Host Defense to Pathology

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Targeting NETosis: nature’s alarm system in cancer progression

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Neutrophils in Intestinal Inflammation: What We Know and What We Could Expect for the Near Future

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Role of phagocyte extracellular traps during Mycobacterium tuberculosis infections and tuberculosis disease processes

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Post-translational modified proteins are biomarkers of autoimmune-processes: NETosis and the inflammatory–autoimmunity connection

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Frontline Science: Anthrax lethal toxin-induced, NLRP1-mediated IL-1β release is a neutrophil and PAD4-dependent event

Greaney, A. J., Portley, M. K., O’Mard, D., Crown, D., Maier, N. K., Mendenhall, M. A., Mayer-Barber, K. D., Leppla, S. H., & Moayeri, M. (2020) · Journal of Leukocyte Biology · doi:10.1002/jlb.4hi0320-028r · Cited by 21

Different glycoforms of alpha-1-acid glycoprotein contribute to its functional alterations in platelets and neutrophils

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The role of anti-citrullinated protein antibody in pathogenesis of RA

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Cardiomyocyte-localized CCDC25 senses NET DNA to promote doxorubicin cardiotoxicity by activating autophagic flux

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The comings and goings of cell-free DNA: Biological and clinical implications

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Thrombosis in Covid-19 and non-Covid-19 pneumonia: role of platelets

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Circulating neutrophil extracellular traps in cats with hypertrophic cardiomyopathy and cardiogenic arterial thromboembolism

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Interferon alpha‐2 treatment reduces circulating neutrophil extracellular trap levels in myeloproliferative neoplasms

Massarenti, L., Knudsen, T. A., Enevold, C., Skov, V., Kjær, L., Larsen, M. K., Larsen, T. S., Hansen, D. L., Hasselbalch, H. C., & Nielsen, C. H. (2023) · British Journal of Haematology · doi:10.1111/bjh.18845 · Cited by 20

Citrullination and the protein code: crosstalk between post-translational modifications in cancer

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Recombinant human ADAMTS13 treatment and anti-NET strategies enhance skin allograft survival in mice

Wong, S. L., Goverman, J. M., Staudinger, C., & Wagner, D. D. (2019) · American Journal of Transplantation · doi:10.1111/ajt.15703 · Cited by 20

Minimum Information and Quality Standards for Conducting, Reporting, and Organizing In Vitro Research

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Deiminated proteins and extracellular vesicles as novel biomarkers in pinnipeds: Grey seal (Halichoerus gryptus) and harbour seal (Phoca vitulina)

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Neutrophil extracellular trap regulators in sickle cell disease: Modulation of gene expression of PADI4, neutrophil elastase, and myeloperoxidase during vaso‐occlusive crisis

Hounkpe, B. W., Chénou, F., Domingos, I. F., Cardoso, E. C., Sobreira, M. J. D. V. C., Araujo, A. S., Lucena-Araujo, A. R., Silva-Neto, P. V. D., Malheiro, A., Fraiji, N. A., et al. (2020) · Research and Practice in Thrombosis and Haemostasis · doi:10.1002/rth2.12463 · Cited by 20

Protectin D1 decreases pancreatitis severity in mice by inhibiting neutrophil extracellular trap formation

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Neutrophil stimulation with citrullinated histone H4 slows down calcium influx and reduces NET formation compared with native histone H4

Shi, L. S., Aymonnier, K., & Wagner, D. D. (2021) · PLoS ONE · doi:10.1371/journal.pone.0251726 · Cited by 20

Uncovering the Oral Dysbiotic Microbiota as Masters of Neutrophil Responses in the Pathobiology of Periodontitis

Prucsi, Z., Płonczyńska, A., Potempa, J., & Sochalska, M. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.729717 · Cited by 20

Platelet factor 4 promotes deep venous thrombosis by regulating the formation of neutrophil extracellular traps

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Post-translational modifications in sepsis-induced organ dysfunction: mechanisms and implications

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Calpain-1 weakens the nuclear envelope and promotes the release of neutrophil extracellular traps

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Baicalin Modulates Glycolysis via the PKC/Raf/MEK/ERK and PI3K/AKT Signaling Pathways to Attenuate IFN‐I‐Induced Neutrophil NETosis

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The Periodontal–Cardiovascular Disease Association: Molecular Mechanisms and Clinical Implications

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