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Cited by 251

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Hepatitis C Virus Infection as an Opportunistic Disease in Persons Infected with Human Immunodeficiency Virus

Sulkowski, Mark S., Mast, Eric E., Seeff, Leonard B., Thomas, David L.·2000·Clinical Infectious Diseases

Abstract

Hepatitis C virus (HCV) is an RNA virus of the Flaviviridae family and is a major cause of chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Owing to shared routes of transmission, HCV and human immunodeficiency virus (HIV) coinfection are common, affecting approximately one-third of all HIV-infected persons in the United States. In addition, HIV coinfection is associated with higher HCV RNA level and a more rapid progression of HCV-related liver disease, which leads to an increased risk of cirrhosis. HCV infection may also impact the course and management of HIV disease, particularly by increasing the risk of antiretroviral drug-induced hepatotoxicity. Thus, chronic HCV infection acts as an opportunistic disease in HIV-infected persons, because the incidence of infection is increased and the natural history of HCV infection is accelerated in coinfected persons. Strategies to prevent primary HCV infection and to modify the progression of HCV-related liver disease are urgently needed for HIV-HCV-coinfected individuals.

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Metadata

Authors
Sulkowski, M. S., Mast, E. E., Seeff, L. B., & Thomas, D. L.
Venue
Clinical Infectious Diseases
Published
2000-04
Volume
30
Issue
s1
Pages
S77-S84
ISSN
  • 1058-4838 (ISSN-L)
  • 1537-6591
OpenAlex
W2151020178
Cited by
251
References
3
FWCI
12.34
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Hepatitis C Virus Infection as an Opportunistic Disease in Persons Infected with Human Immunodeficiency Virus. https://app.cochat.ai/papers/10.1086/313842
The paper
Sulkowski, M. S., Mast, E. E., Seeff, L. B., & Thomas, D. L. (2000). Hepatitis C Virus Infection as an Opportunistic Disease in Persons Infected with Human Immunodeficiency Virus. Clinical Infectious Diseases. https://doi.org/10.1086/313842

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.