The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.
Virulence of Three Distinct Cryptosporidium parvum Isolates for Healthy Adults
Abstract
The infectivity of three Cryptosporidium parvum isolates (Iowa [calf], UCP [calf], and TAMU [horse]) of the C genotype was investigated in healthy adults. After exposure, volunteers recorded the number and form of stools passed and symptoms experienced. Oocyst excretion was assessed by immunofluorescence. The ID50 differed among isolates: Iowa, 87 (SE, 19; 95% confidence interval [CI], 48.67-126); UCP, 1042 (SE, 1000; 95% CI, 0-3004); and TAMU, 9 oocysts (SE, 2.34; 95% CI, 4.46-13.65); TAMU versus Iowa, P=.002 or UCP, P=.019. Isolates also differed significantly (P=.045) in attack rate between TAMU (86%) and Iowa (52%) or UCP (59%). A trend toward a longer duration of diarrhea was seen for the TAMU (94.5 h) versus UCP (81.6 h) and Iowa (64.2 h) isolates. C. parvum isolates of the C genotype differ in their infectivity for humans.
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A SIMPLE METHOD OF ESTIMATING FIFTY PER CENT ENDPOINTS12
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The Infectivity of Cryptosporidium parvum in Healthy Volunteers
DuPont, H. L., Chappell, C. L., Sterling, C. R., Okhuysen, P. C., Rose, J. B., & Jakubowski, W. (1995) · New England Journal of Medicine · doi:10.1056/nejm199503303321304 · Cited by 889
Self-citationSurvival of Cryptosporidium parvum oocysts under various environmental pressures
Robertson, L. J., Campbell, A. T., & Smith, H. V. (1992) · Applied and Environmental Microbiology · doi:10.1128/aem.58.11.3494-3500.1992 · Cited by 530
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Self-citationPeng, M. M., Xiao, L., Freeman, A. R., Arrowood, M. J., Escalante, A. A., Weltman, A. C., Ong, C., Kenzie, W. R. M., Lal, A. A., & Beard, C. B. (1997) · Emerging infectious diseases · doi:10.3201/eid0304.970423 · Cited by 351
Morgan, U. M., Constantine, C. C., Forbes, D. A., & Thompson, R. C. A. (1997) · The Journal of Parasitology · doi:10.2307/3284275 · Cited by 274
Cryptosporidium Infection and CD4 Counts
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Self-citationCryptosporidium parvum: Intensity of Infection and Oocyst Excretion Patterns in Healthy Volunteers
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Community structures of fecal bacteria in cattle from different animal feeding operations
Shanks, O. C., Kelty, C. A., Archibeque, S., Jenkins, M., Newton, R. J., McLellan, S. L., Huse, S. M., & Sogin, M. L. (2011) · Applied and Environmental Microbiology · doi:10.1128/aem.02988-10 · Cited by 359
Cryptosporidium in humans and animals—a one health approach to prophylaxis
Ryan, U., Zahedi, A., & Paparini, A. (2016) · Parasite Immunology · doi:10.1111/pim.12350 · Cited by 258
A Rapid and Specific Method for the Detection of Indole in Complex Biological Samples
Darkoh, C., Chappell, C., Gonzales, C., & Okhuysen, P. (2015) · Applied and Environmental Microbiology · doi:10.1128/aem.02787-15 · Cited by 156
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Metadata
- Authors
- Okhuysen, P. C., Chappell, C. L., Crabb, J. H., Sterling, C. R., & DuPont, H. L.
- Venue
- The Journal of Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 1999-10
- Volume
- 180
- Issue
- 4
- Pages
- 1275-1281
- ISSN
- 0022-1899 (ISSN-L)
- 1537-6613
- OpenAlex
- W2115474893
- Cited by
- 466
- References
- 21
- FWCI
- 12.68
- Type
- journal article
- Language
- en
- Open access
- closed
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