The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Dual Infection of Infants by Human Metapneumovirus and Human Respiratory Syncytial Virus Is Strongly Associated with Severe Bronchiolitis
Open accessAbstract
The association between severe bronchiolitis and dual infection by human metapneumovirus (hMPV) and human respiratory syncytial virus (hRSV) was investigated in <2-year-old infants with bronchiolitis who were admitted to the hospital during the 2001-2002 winter season. hMPV in nasopharyngeal aspirate and/or cells and fluid collected by nonbronchoscopic bronchoalveolar lavage was detected by reverse transcriptase-polymerase chain reaction (RT-PCR). hRSV was detected in nasopharyngeal aspirate and/or cells and fluid collected by nonbronchoscopic bronchoalveolar lavage by enzyme immunoassay, tissue culture, and RT-PCR. Dual infection with hMPV and hRSV confers a 10-fold increase in relative risk (RR) of admission to a pediatric intensive-care unit for mechanical ventilation (RR, 10.99 [95% confidence interval, 5.0-24.12]; P<.001, by Fisher exact test). Dual infection by hMPV and hRSV is associated with severe bronchiolitis.
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Citations
Cites
Evidence of human metapneumovirus in Australian children
Nissen, M. D., Mackay, I. M., Withers, S. J., Siebert, D. J., & Sloots, T. P. (2002) · Medical Journal of Australia · doi:10.5694/j.1326-5377.2002.tb04354.x · Cited by 199
Cited by
Respiratory Viral Infections in Infants: Causes, Clinical Symptoms, Virology, and Immunology
Tregoning, J. S., & Schwarze, J. (2010) · Clinical Microbiology Reviews · doi:10.1128/cmr.00032-09 · Cited by 747
Human Bocavirus and Acute Wheezing in Children
Allander, T., Jartti, T., Gupta, S., Niesters, H. G. M., Lehtinen, P., usterback, R., Vuorinen, T., Waris, M., Bjerkner, A., Tiveljung-Lindell, A., et al. (2007) · Clinical Infectious Diseases · doi:10.1086/512196 · Cited by 555
Florin, T. A., Plint, A. C., & Zorc, J. J. (2017) · The Lancet · doi:10.1016/s0140-6736(16)30951-5 · Cited by 452
Piedra, P. A. (2012) · Archives of Pediatrics & Adolescent Medicine · doi:10.1001/archpediatrics.2011.1669 · Cited by 398
Epidemiology of Human Metapneumovirus
Kahn, J. S. (2006) · Clinical Microbiology Reviews · doi:10.1128/cmr.00014-06 · Cited by 355
Metadata
- Authors
- Semple, M. G., Cowell, A., Dove, W., Greensill, J., McNamara, P. S., Halfhide, C., Shears, P., Smyth, R. L., & Hart, C. A.
- Venue
- The Journal of Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2005-02
- Volume
- 191
- Issue
- 3
- Pages
- 382-386
- ISSN
- 0022-1899 (ISSN-L)
- 1537-6613
- OpenAlex
- W2114622973
- Cited by
- 430
- References
- 1
- FWCI
- 21.59
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Dual Infection of Infants by Human Metapneumovirus and Human Respiratory Syncytial Virus Is Strongly Associated with Severe Bronchiolitis. https://app.cochat.ai/papers/10.1086/426457
- The paper
- Semple, M. G., Cowell, A., Dove, W., Greensill, J., McNamara, P. S., Halfhide, C., Shears, P., Smyth, R. L., & Hart, C. A. (2005). Dual Infection of Infants by Human Metapneumovirus and Human Respiratory Syncytial Virus Is Strongly Associated with Severe Bronchiolitis. The Journal of Infectious Diseases. https://doi.org/10.1086/426457
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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