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Cited by 239

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A motion-incorporated reconstruction method for gated PET studies

Open access
Qiao, Feng, Pan, Tinsu, Clark, John W, Mawlawi, Osama R·2006·Physics in Medicine and Biology

Abstract

Cardiac and respiratory motion artefacts in PET imaging have been traditionally resolved by acquiring the data in gated mode. However, gated PET images are usually characterized by high noise content due to their low photon statistics. In this paper, we present a novel 4D model for the PET imaging system, which can incorporate motion information to generate a motion-free image with all acquired data. A computer simulation and a phantom study were conducted to test the performance of this approach. The computer simulation was based on a digital phantom that was continuously scaled during data acquisition. The phantom study, on the other hand, used two spheres in a tank of water, all of which were filled with (18)F water. One of the spheres was stationary while the other moved in a sinusoidal fashion to simulate tumour motion in the thorax. Data were acquired using both 4D CT and gated PET. Motion information was derived from the 4D CT images and then used in the 4D PET model. Both studies showed that this 4D PET model had a good motion-compensating capability. In the phantom study, this approach reduced quantification error of the radioactivity concentration by 95% when compared to a corresponding static acquisition, while signal-to-noise ratio was improved by 210% when compared to a corresponding gated image.

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Metadata

Authors
Qiao, F., Pan, T., Clark, J. W., & Mawlawi, O. R.
Venue
Physics in Medicine and Biology
Published
2006-07-20
Volume
51
Issue
15
Pages
3769-3783
ISSN
  • 0031-9155 (ISSN-L)
  • 1361-6560
OpenAlex
W2070480087
Cited by
239
References
2
FWCI
13.10
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: A motion-incorporated reconstruction method for gated PET studies. https://app.cochat.ai/papers/10.1088/0031-9155/51/15/012
The paper
Qiao, F., Pan, T., Clark, J. W., & Mawlawi, O. R. (2006). A motion-incorporated reconstruction method for gated PET studies. Physics in Medicine and Biology. https://doi.org/10.1088/0031-9155/51/15/012

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.