The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.
Nearly complete regression of tumors via collective behavior of magnetic nanoparticles in hyperthermia
Open accessAbstract
One potential cancer treatment selectively deposits heat to the tumor through activation of magnetic nanoparticles inside the tumor. This can damage or kill the cancer cells without harming the surrounding healthy tissue. The properties assumed to be most important for this heat generation (saturation magnetization, amplitude and frequency of external magnetic field) originate from theoretical models that assume non-interacting nanoparticles. Although these factors certainly contribute, the fundamental assumption of 'no interaction' is flawed and consequently fails to anticipate their interactions with biological systems and the resulting heat deposition. Experimental evidence demonstrates that for interacting magnetite nanoparticles, determined by their spacing and anisotropy, the resulting collective behavior in the kilohertz frequency regime generates significant heat, leading to nearly complete regression of aggressive mammary tumors in mice.
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Cites
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Cited by
The big picture on nanomedicine: the state of investigational and approved nanomedicine products
Etheridge, M. L., Campbell, S. A., Erdman, A. G., Haynes, C. L., Wolf, S. M., & McCullough, J. (2013) · Nanomedicine: Nanotechnology, Biology and Medicine · doi:10.1016/j.nano.2012.05.013 · Cited by 1,088
“Iron oxide particles are used in MR contrast(79,80) and cancer thermal therapies.(75,81) Colloidal gold is being used in systemic delivery of therapeutic biologicals(82) and for cancer thermal therapies.”
Fundamentals and advances in magnetic hyperthermia
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Cancer therapy with iron oxide nanoparticles: Agents of thermal and immune therapies
Soetaert, F., Korangath, P., Serantes, D., Fiering, S., & Ivkov, R. (2020) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2020.06.025 · Cited by 406
Self-citationSize-Dependent Heating of Magnetic Iron Oxide Nanoparticles
Tong, S., Quinto, C. A., Zhang, L., Mohindra, P., & Bao, G. (2017) · ACS Nano · doi:10.1021/acsnano.7b01762 · Cited by 401
Metadata
- Authors
- Dennis, C. L., Jackson, A. J., Borchers, J. A., Hoopes, P. J., Strawbridge, R., Foreman, A. R., van Lierop, J., Grüttner, C., & Ivkov, R.
- Venue
- Nanotechnology
- Publisher
- IOP Publishing
- Published
- 2009-09-03
- Volume
- 20
- Issue
- 39
- Pages
- 395103
- ISSN
- 0957-4484 (ISSN-L)
- 1361-6528
- OpenAlex
- W2003581316
- Cited by
- 254
- References
- 32
- FWCI
- 8.93
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Dennis, C. L., Jackson, A. J., Borchers, J. A., Hoopes, P. J., Strawbridge, R., Foreman, A. R., van Lierop, J., Grüttner, C., & Ivkov, R. (2009). Nearly complete regression of tumors via collective behavior of magnetic nanoparticles in hyperthermia. Nanotechnology. https://doi.org/10.1088/0957-4484/20/39/395103
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
