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Canine olfaction as an alternative to analytical instruments for disease diagnosis: understanding ‘dog personality’ to achieve reproducible results
Open accessAbstract
Recent literature has touted the use of canine olfaction as a diagnostic tool for identifying pre-clinical disease status, especially cancer and infection from biological media samples. Studies have shown a wide range of outcomes, ranging from almost perfect discrimination, all the way to essentially random results. This disparity is not likely to be a detection issue; dogs have been shown to have extremely sensitive noses as proven by their use for tracking, bomb detection and search and rescue. However, in contrast to analytical instruments, dogs are subject to boredom, fatigue, hunger and external distractions. These challenges are of particular importance in a clinical environment where task repetition is prized, but not as entertaining for a dog as chasing odours outdoors. The question addressed here is how to exploit the intrinsic sensitivity and simplicity of having a dog simply sniff out disease, in the face of variability in behavior and response.
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“In recent years, canine olfaction has also been more recognized as a diagnostic tool for identifying pre-clinical disease status, such as diabetes (ketones), different forms of cancer, and infections from biological media samples [37].”
From A One Health Perspective on the Human-Companion Animal Relationship with Emphasis on Zoonotic Aspects. (2020) · cites this paper as [37]
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Cited by
Sorted by citations
Overgaauw, P. A. M., Vinke, C. M., van Hagen, M. A. E., & Lipman, L. J. A. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17113789 · Cited by 301
“In recent years, canine olfaction has also been more recognized as a diagnostic tool for identifying pre-clinical disease status, such as diabetes (ketones), different forms of cancer, and infections from biological media samples [37].”
Method
Metadata
- Authors
- Hackner, K., & Pleil, J.
- Affiliations
- Universitätsklinikum Krems (AT)
- Environmental Protection Agency (US)
- Corresponding author
- Hackner, Klaus
- Pleil, Joachim
- Venue
- Journal of Breath Research
- Publisher
- IOP Publishing
- Published
- 2017-01-09
- Volume
- 11
- Issue
- 1
- Pages
- 012001
- ISSN
- 1752-7155 (ISSN-L)
- 1752-7163
- PMC
- PMC6146943
- OpenAlex
- W2570518273
- Cited by
- 46
- References
- 1
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 3 · 2023: 4 · 2022: 9 · 2021: 9 · 2020: 4 · 2019: 4 · 2018: 3 · 2017: 7
- FWCI
- 2.22
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Breath Research (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- U.S. Environmental Protection Agency
- Office of Research and Development
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Advanced Chemical Sensor Technologies
- Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Human-Animal Interaction Studies
- Life Sciences › Neuroscience › Sensory Systems › Olfactory and Sensory Function Studies
- Keywords
- canine olfaction, disease diagnosis, cancer detection, infection detection, dog personality, reproducibility, odor discrimination, breath analysis
- MeSH terms
- Animals, Chemistry Techniques, Analytical, Dogs, Neoplasms, Personality, Smell, Reproducibility of Results
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- CoChat. (2026). Citation check: Canine olfaction as an alternative to analytical instruments for disease diagnosis: understanding ‘dog personality’ to achieve reproducible results. https://app.cochat.ai/papers/10.1088/1752-7163/aa5524
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- Hackner, K., & Pleil, J. (2017). Canine olfaction as an alternative to analytical instruments for disease diagnosis: understanding ‘dog personality’ to achieve reproducible results. Journal of Breath Research. https://doi.org/10.1088/1752-7163/aa5524
