The DOI matches its Crossref record; 131 of the 131 references it cites were found in a registry or an index.
Extracellular Matrix Cell Adhesion Peptides: Functional Applications in Orthopedic Materials
Abstract
This review describes research on selected peptide sequences that affect cell adhesion as it applies in orthopedic applications. Of particular interest are the integrin-binding RGD peptides and heparin-binding peptides. The influence of these peptides on cell adhesion is described. Cell adhesion is defined as a sequence of four steps: cell attachment, cell spreading, organization of an actin cytoskeleton, and formation of focal adhesions. RGD sequences clearly influence cell attachment and spreading, whereas heparin-binding sequences appear to be less efficient. Collectively, these sequences appear to promote all steps of cell adhesion in certain cell types. This review also addresses issues related to peptide immobilization, as well as potential complexities that may develop as a result of using these versatile cell-binding sequences. Also described are future directions in the field concerning use of existing and more sophisticated peptide substrata.
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Cites
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RGD AND OTHER RECOGNITION SEQUENCES FOR INTEGRINS
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Searching for Peptide Ligands with an Epitope Library
Scott, J. K., & Smith, G. P. (1990) · Science · doi:10.1126/science.1696028 · Cited by 2,084
Integrins and other cell adhesion molecules
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PROTEOGLYCANS: STRUCTURES AND INTERACTIONS
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Cited by
Biocompatible polymer materials: Role of protein–surface interactions
Chen, H., Yuan, L., Song, W., Wu, Z., & Li, D. (2008) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2008.07.006 · Cited by 706
Sreejalekshmi, K. G., & Nair, P. D. (2011) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.32980 · Cited by 81
Yang, Z., Liu, M., Yang, Y., Zheng, M., Yang, Y., Liu, X., & Tan, J. (2020) · RSC Advances · doi:10.1039/c9ra08575k · Cited by 58
Wang, H., Yuan, C., Lin, K., Zhu, R., & Zhang, S. (2021) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2021.761911 · Cited by 16
Metadata
- Authors
- LeBaron, R. G., & Athanasiou, K. A.
- Venue
- Tissue Engineering
- Publisher
- SAGE Publications
- Published
- 2000-04
- Volume
- 6
- Issue
- 2
- Pages
- 85-103
- ISSN
- 1076-3279 (ISSN-L)
- 1557-8690
- OpenAlex
- W1980947790
- Cited by
- 306
- References
- 131
- FWCI
- 5.85
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
