The DOI matches its Crossref record; 50 of the 50 references it cites were found in a registry or an index.
Mitochondrial Dynamics in Diabetes
Open accessAbstract
Mitochondria are at the center of cellular energy metabolism and regulate cell life and death. The cell biological aspect of mitochondria, especially mitochondrial dynamics, has drawn much attention through implications in human pathology, including neurological disorders and metabolic diseases. Mitochondrial fission and fusion are the main processes governing the morphological plasticity and are controlled by multiple factors, including mechanochemical enzymes and accessory proteins. Emerging evidence suggests that mitochondrial dynamics plays an important role in metabolism-secretion coupling in pancreatic β-cells as well as complications of diabetes. This review describes an overview of mechanistic and functional aspects of mitochondrial fission and fusion, and comments on the recent advances connecting mitochondrial dynamics with diabetes and diabetic complications.
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“Another report also showed that downregulation of Fis1 decreased the ROS level in acute high-glucose stimulation (171).”
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Self-citationMitofusin 2 tethers endoplasmic reticulum to mitochondria
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Mitochondrial dysfunction and type 2 diabetes
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OPA1 Controls Apoptotic Cristae Remodeling Independently from Mitochondrial Fusion
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Cited by
ER Tubules Mark Sites of Mitochondrial Division
Friedman, J. R., Lackner, L. L., West, M., DiBenedetto, J. R., Nunnari, J., & Voeltz, G. K. (2011) · Science · doi:10.1126/science.1207385 · Cited by 2,072
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Erk2 Phosphorylation of Drp1 Promotes Mitochondrial Fission and MAPK-Driven Tumor Growth
Kashatus, J. A., Nascimento, A., Myers, L. J., Sher, A., Byrne, F. L., Hoehn, K. L., Counter, C. M., & Kashatus, D. F. (2015) · Molecular Cell · doi:10.1016/j.molcel.2015.01.002 · Cited by 698
Hanschmann, E.-M., Godoy, J. R., Berndt, C., Hudemann, C., & Lillig, C. H. (2013) · Antioxidants & Redox Signaling · doi:10.1089/ars.2012.4599 · Cited by 677
Mitochondrial dynamics in type 2 diabetes: Pathophysiological implications
Rovira-Llopis, S., Bañuls, C., Diaz-Morales, N., Hernandez-Mijares, A., Rocha, M., & Victor, V. M. (2017) · Redox Biology · doi:10.1016/j.redox.2017.01.013 · Cited by 657
Metadata
- Authors
- Yoon, Y., Galloway, C. A., Jhun, B. S., & Yu, T.
- Venue
- Antioxidants & Redox Signaling
- Publisher
- SAGE Publications
- Published
- 2011-02
- Volume
- 14
- Issue
- 3
- Pages
- 439-457
- ISSN
- 1523-0864 (ISSN-L)
- 1557-7716
- OpenAlex
- W2016658073
- Cited by
- 215
- References
- 50
- FWCI
- 4.49
- Type
- journal article
- Language
- en
- Open access
- green
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