Atomoxetine Use Associated with Onset of a Motor Tic
Abstract
Patients with attention-deficit/hyperactivity disorder (ADHD) are at increased risk for Tourette's Disorder and other tic disorders. Stimulant medications and bupropion have been associated with the onset or exacerbation of a tic disorder. The selective norepinephrine reuptake inhibitor, atomoxetine, has been proposed to be an alternative medication for patients with ADHD and a comorbid tic disorder. This paper reviews a case study in which the onset of a motor tic was associated with a trial of the medication atomoxetine. Further research is needed to determine if atomoxetine is an appropriate alternative medication in patients with ADHD and a comorbid tic disorder.
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A few case reports have described exacerbation of tics during atomoxetine treatment.
“On the other hand, a few case reports have described exacerbation of tics during atomoxetine treatment [43, 77, 79, 105, 106, 126].”
From European guidelines on managing adverse effects of medication for ADHD (2011) · cites this paper as [77]
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- Authors
- Ledbetter, M.
- Affiliations
- University of Oklahoma - Tulsa (US)
- Corresponding author
- Ledbetter, Marcialee
- Venue
- Journal of Child and Adolescent Psychopharmacology
- Publisher
- SAGE Publications
- Published
- 2005-04
- Volume
- 15
- Issue
- 2
- Pages
- 331-333
- ISSN
- 1044-5463 (ISSN-L)
- 1557-8992
- OpenAlex
- W1970036342
- Cited by
- 40
- References
- 9
- Citations by year
- 2026: 1 · 2024: 2 · 2023: 1 · 2022: 1 · 2021: 1 · 2018: 2 · 2017: 1 · 2016: 3 · 2015: 2 · 2014: 2 · 2013: 1 · 2012: 3
- FWCI
- 2.19
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Child and Adolescent Psychopharmacology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Social Sciences › Psychology › Clinical Psychology › Stuttering Research and Treatment
- Keywords
- atomoxetine, Tourette syndrome, tic disorders, attention deficit hyperactivity disorder, selective norepinephrine reuptake inhibitors, bupropion, ADHD medication
- MeSH terms
- Atomoxetine Hydrochloride, Attention Deficit Disorder with Hyperactivity, Child, Humans, Male, Propylamines, Tic Disorders, Tics
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