Cited by 143Obsessive-Compulsive Spectrum DisordersAttention Deficit Hyperactivity DisorderStuttering Research and Treatment

Attention deficit hyperactivity disorder, tics and Tourette’s syndrome: the relationship and treatment implications. A commentary

M. Robertson*, Mary·2006·European Child & Adolescent Psychiatry

Abstract

Tourette's Syndrome (TS) is now recognised to be a common childhood onset neurodevelopmental disorder. Attention deficit hyperactivity disorder (ADHD) is also a common childhood disorder. There are many cases in which the two disorders are comorbid. The reasons for this are unclear, but the comorbidity does not necessarily point to one genetic cause. Sleep is also often disturbed in individuals with TS and ADHD. The treatment implications of ADHD in the setting of tics or TS are important. Clonidine is suggested as a first line treatment. It was once thought that stimulants were contraindicated in the treatment of ADHD in the setting of TS, whereas it is suggested that they may be safe, but should be used judiciously. In addition, it was once thought that the combination of stimulants and clonidine was contraindicated, but from a large study the combination does appear to be safe. A relatively new medication for ADHD is atomoxetine, and although not documented widely in the setting of tics and TS, it may prove useful in this setting; further research is required. This commentary briefly discusses the comorbidity between TS and ADHD and offers treatment suggestions.

Integrity signals

Registry

Crossref · 10.1007/s00787-006-0505-z

Cites

92 of 92 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • For clonidine, there exists some evidence that it may reduce tics in frequency and severity, as well as improve ADHD symptoms; but worsening of tics may be seen in about a quarter of cases.

    “For clonidine, which is only occasionally used in Europe to treat TD and/or ADHD, but recommended by some authors (especially where TD is the predominant disorder) [116], there exists some evidence that it may reduce tics in frequency and severity, as well as improve ADHD symptoms; but on the other hand, worsening of tics may be seen in about a quarter of cases [3].”

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
M. Robertson*, M.
Venue
European Child & Adolescent Psychiatry
Published
2006-02
Volume
15
Issue
1
Pages
1-11
ISSN
  • 1018-8827 (ISSN-L)
  • 1435-165X
OpenAlex
W1963644974
Cited by
143
References
91
Citations by year
2026: 4 · 2025: 1 · 2024: 1 · 2023: 4 · 2022: 2 · 2021: 10 · 2020: 15 · 2019: 3 · 2018: 1 · 2017: 3 · 2016: 10 · 2015: 5 · 2014: 5 · 2013: 11 · 2012: 8
FWCI
1.95
Type
journal article
Language
en
Open access
closed
Locations
  • European Child & Adolescent Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
  • Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
  • Social Sciences › Psychology › Clinical Psychology › Stuttering Research and Treatment
Keywords
attention deficit hyperactivity disorder, Tourette syndrome, tics, comorbidities, pediatric neurodevelopmental disorders, sleep disorders, clonidine, stimulants, atomoxetine, combination therapy, therapeutic implications
MeSH terms
Atomoxetine Hydrochloride, Central Nervous System Stimulants, Attention Deficit Disorder with Hyperactivity, Tourette Syndrome, Humans, Methylphenidate, Propylamines, Adrenergic Uptake Inhibitors, Tics

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review