Treatment of youth depression in primary care under usual practice conditions: Observational findings from youth partners in care
Open accessAbstract
OBJECTIVES: The effectiveness of treatments for youth depression in primary care, under usual practice conditions, is largely unstudied. This study aims at estimating the effect of "appropriate treatment," defined as treatment that approximates guideline standards, on clinical outcomes for depressed primary care youth patients by using observational analyses from a randomized trial. METHODS: Participants were 344 youths aged 13-21 enrolled in the Youth Partners in Care trial. Youths screening positive for depression from six primary care practices in five different health care organizations were randomly assigned to either (1) usual care enhanced by provider education on depression evaluation and management, or (2) a quality improvement (QI) intervention designed to improve access to antidepressant medications and/or cognitive behavior therapy for depression; usual practice conditions otherwise applied. Observational analysis was conducted on the effects of appropriate treatment (antidepressant medication use by algorithms or 6 or more psychotherapy visits) on severe depression (Center for Epidemiologic Studies-Depression score ≥ 24) at 6 months. Selection into treatment is accounted for by using instrumental variables analysis, with randomized QI intervention status as the instrument. RESULTS: At 6 months, youths receiving "appropriate treatment," compared with others, were significantly less likely to have severe depression (10.9% vs. 45.2%, p<0.0001). Similar findings were observed among youths with depressive disorders and sub-syndromal depressive symptoms, and among Latino and other youths. CONCLUSIONS: Among depressed primary care youths, care that approximates guideline standards but retains leniency substantially reduces the likelihood of severe depression at 6 months. Such findings apply to youths with or without depressive disorder, and among Latino youth.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Multiple randomized controlled trials of adolescents with depression in primary care have shown that collaborative care models reduce depression and increase adherence to evidence-based treatments.
“Additionally, several randomized controlled trials focusing on adolescents with depression in primary care settings have demonstrated the effectiveness of CCMs in decreasing depression and improving adherence to evidenced-base treatments.107-110”
From Evidence-based youth suicide prevention and intervention in pediatric primary care settings. (2024) · cites this paper as [108]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
The CES-D Scale: A Self-Report Depression Scale for Research in the General Population
Radloff, L. S. (1977) · Applied Psychological Measurement · doi:10.1177/014662167700100306 · Cited by 53,267 · see citing works
Identification of Causal Effects Using Instrumental Variables
Angrist, J. D., Imbens, G. W., & Rubin, D. B. (1996) · Journal of the American Statistical Association · doi:10.1080/01621459.1996.10476902 · Cited by 4,230 · see citing works
Mental Health: A Report of the Surgeon General
United States. Public Health Service. Office of the Surgeon General (1999) · PsycEXTRA Dataset · doi:10.1037/e636982009-001 · Cited by 3,105 · see citing works
Performance of a Five-Item Mental Health Screening Test
Berwick, D. M., Murphy, J. M., Goldman, P. A., Ware, J. E., Barsky, A. J., & Weinstein, M. C. (1991) · Medical Care · doi:10.1097/00005650-199102000-00008 · Cited by 1,660 · see citing works
Design of Observational Studies
Rosenbaum, P. R. (2010) · Springer Series in Statistics · doi:10.1007/978-1-4419-1213-8 · Cited by 1,150 · see citing works
Birmaher, B., & Brent, D. (2007) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/chi.0b013e318145ae1c · Cited by 1,056 · see citing works
Wells, K. B., Sherbourne, C., Schoenbaum, M., Duan, N., Meredith, L., Unützer, J., Miranda, J., Carney, M. F., & Rubenstein, L. V. (2000) · JAMA · doi:10.1001/jama.283.2.212 · Cited by 1,021 · see citing works
Emslie, G. J. (1997) · Archives of General Psychiatry · doi:10.1001/archpsyc.1997.01830230069010 · Cited by 969 · see citing works
Predictive Margins with Survey Data
Graubard, B. I., & Korn, E. L. (1999) · Biometrics · doi:10.1111/j.0006-341x.1999.00652.x · Cited by 875 · see citing works
Does More Intensive Treatment of Acute Myocardial Infarction in the Elderly Reduce Mortality?
McClellan, M. (1994) · JAMA · doi:10.1001/jama.1994.03520110039026 · Cited by 777 · see citing works
Brent, D. A., Emslie, G. J., Clarke, G. N., Wagner, K. D., Asarnow, J. R., Keller, M., Vitiello, B., Ritz, L., Iyengar, S., Abebe, K. Z., et al. (2008) · JAMA · doi:10.1001/jama.299.8.901 · Cited by 705 · see citing works
Clarke, G. N., Hawkins, W., Murphy, M., Sheeber, L. B., Lewinsohn, P. M., & Seeley, J. R. (1995) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199503000-00016 · Cited by 672 · see citing works
Youth risk behavior surveillance - United States, 2009.
Eaton, D. K., Kann, L. K., Kinchen, S., Shanklin, S. L., Ross, J. G., Hawkins, J., Harris, W. A., Lowry, R., McManus, T., Chyen, D., et al. (2010) · PubMed · Cited by 631 · see citing works
Mental Health: A Report of the Surgeon General
Smoyak, S. A. (2000) · Journal of Psychosocial Nursing and Mental Health Services · doi:10.3928/0279-3695-20000201-03 · Cited by 603 · see citing works
A Randomized Effectiveness Trial of Interpersonal Psychotherapy forDepressed Adolescents
Mufson, L., Dorta, K. P., Wickramaratne, P., Nomura, Y., Olfson, M., & Weissman, M. M. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.6.577 · Cited by 537 · see citing works
Prevention of Depression in At-Risk Adolescents
Garber, J., Clarke, G. N., Weersing, V. R., Beardslee, W. R., Brent, D. A., Gladstone, T. R. G., DeBar, L., Lynch, F. L., D’Angelo, E. J., Hollon, S. D., et al. (2009) · JAMA · doi:10.1001/jama.2009.788 · Cited by 507 · see citing works
Clarke, G., Rohde, P., Lewinsohn, P., Hops, H., & Seeley, J. (1999) · Journal of the American Academy of Child and Adolescent Psychiatry · doi:10.1097/00004583-199903000-00014 · Cited by 485 · see citing works
Wagner, K. D. (2003) · JAMA · doi:10.1001/jama.290.8.1033 · Cited by 413 · see citing works
Bayesian inference for causal effects in randomized experiments with noncompliance
Imbens, G. W., & Rubin, D. B. (1997) · The Annals of Statistics · doi:10.1214/aos/1034276631 · Cited by 382 · see citing works
Youth Psychotherapy Outcome Research: A Review and Critique of the Evidence Base
Weisz, J. R., Doss, A. J., & Hawley, K. M. (2004) · Annual Review of Psychology · doi:10.1146/annurev.psych.55.090902.141449 · Cited by 356 · see citing works
Wagner, K. D., Robb, A. S., Findling, R. L., Jin, J., Gutierrez, M. M., & Heydorn, W. E. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.6.1079 · Cited by 309 · see citing works
Jensen, P. S., Bhatara, V. S., Vitiello, B., Hoagwood, K., FEIL, M., & Burke, L. B. (1999) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199905000-00017 · Cited by 262 · see citing works
How can care for depression become more cost-effective?
Sturm, R. (1995) · JAMA · doi:10.1001/jama.273.1.51 · Cited by 239 · see citing works
Horwitz, S. M., Leaf, P. J., Leventhal, J. M., Forsyth, B. W. C., & Speechley, K. N. (1992) · PEDIATRICS · doi:10.1542/peds.89.3.480 · Cited by 231 · see citing works
Reliability of the services assessment for children and adolescents
Horwitz, S. M., Hoagwood, K., Stiffman, A. R., Summerfeld, T., Weisz, J. R., Costello, E. J., Rost, K., Bean, D. L., Cottler, L., Leaf, P. J., et al. (2001) · Psychiatric Services · doi:10.1176/appi.ps.52.8.1088 · Cited by 192 · see citing works
Estimating probit models with self-selected treatments
Bhattacharya, J., Goldman, D. P., & McCaffrey, D. (2005) · Statistics in Medicine · doi:10.1002/sim.2226 · Cited by 191 · see citing works
Moving beyond Parity — Mental Health and Addiction Care under the ACA
Barry, C. L., & Huskamp, H. (2011) · New England Journal of Medicine · doi:10.1056/nejmp1108649 · Cited by 184 · see citing works
Influence of Parental Concordance for Psychiatric Disorders on Psychopathology in Offspring
Dierker, L. C., Merikangas, K. R., & Szatmari, P. (1999) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199903000-00015 · Cited by 178 · see citing works
Robust, Accurate Confidence Intervals with a Weak Instrument: Quarter of Birth and Education
Imbens, G. W., & Rosenbaum, P. R. (2004) · Journal of the Royal Statistical Society Series A (Statistics in Society) · doi:10.1111/j.1467-985x.2004.00339.x · Cited by 171 · see citing works
The Effects of Primary Care Depression Treatment on Patients' Clinical Status and Employment
Schoenbaum, M., Unützer, J., McCaffrey, D., Duan, N., Sherbourne, C. D., & Wells, K. B. (2002) · Health Services Research · doi:10.1111/1475-6773.01086 · Cited by 163 · see citing works
Goodyer, I. M., Dubicka, B., Wilkinson, P. O., Kelvin, R. G., Roberts, C., Byford, S., Breen, S., Ford, C., Barrett, B. M., Leech, A., et al. (2008) · Health Technology Assessment · doi:10.3310/hta12140 · Cited by 144 · see citing works
Adolescents With Depression—Reply
(2004) · JAMA · doi:10.1001/jama.292.21.2578-c · Cited by 129 · see citing works
Hughes, C. W., Emslie, G. J., Crismon, M. L., Wagner, K. D., Birmaher, B. B., Geller, B., Pliszka, S. R., Ryan, N. D., Strober, M. A., Trivedi, M. H., et al. (1999) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199911000-00020 · Cited by 125 · see citing works
Randomization as an Instrumental Variable
Heckman, J. J. (1995) · National Bureau of Economic Research · doi:10.3386/t0184 · Cited by 108 · see citing works
Effects of Primary Care Depression Treatment on Minority Patients'Clinical Status and Employment
Miranda, J. M., Schoenbaum, M., Sherbourne, C. D., Duan, N., & Wells, K. B. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.8.827 · Cited by 104 · see citing works
Antidepressant Medications in Children
Vitiello, B., & Swedo, S. E. (2004) · New England Journal of Medicine · doi:10.1056/nejmp038248 · Cited by 86 · see citing works
Asarnow, J. R., Jaycox, L. H., Tang, L., Duan, N., LaBorde, A. P., Zeledon, L. R., Anderson, M., Murray, P. J., Landon, C., Rea, M. M., et al. (2009) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2009.08121909 · Cited by 85 · see citing works
Self-citationSuicidality in Children and Adolescents Being Treated With Antidepressant Medications
(2004) · PsycEXTRA Dataset · doi:10.1037/e307312005-001 · Cited by 65 · see citing works
Understanding and Evaluating Research in Applied and Clinical Settings
Birmaher, B. B. (2006) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/01.chi.0000251256.51173.c5 · Cited by 37 · see citing works
Asarnow, J. R., Jaycox, L. H., Duan, N., LaBorde, A. P., Rea, M. M., Murray, P., Anderson, M., Landon, C., Tang, L., & Wells, K. B. (2005) · JAMA · doi:10.1001/jama.293.3.311 · Cited by 27 · see citing works
Instrumental variable methods for effectiveness research
Sturm, R. (1998) · International Journal of Methods in Psychiatric Research · doi:10.1002/mpr.31 · Cited by 18 · see citing works
Randomization Inference with an Instrumental Variable
Imbens, G. W., & Rosenbaum, P. R. (2005) · Journal of the Royal Statistical Society Series A (Statistics in Society) · Cited by 8 · see citing works
Campo, J. V., & Bridge, J. A. (2009) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2009.09070981 · Cited by 6 · see citing works
Flagged first, then by citations
Research works printed but not linked: 5
- Asarnow JR. Carlson G. Schuster M. Miranda J. Jackson-Triche M. Wells KB. Rubenstein L. Unutzer J. Miranda J, et al. Partners in Care: Clinician Guide to Depression Assessment and Management in Primary Care Settings. Los Angeles, CA: UCLA School of Medicine; Santa Monica, CA: RAND; 1999. 1996. Youths Partners in Care: Clinician Guide to Depression Assessment and Management Among Youth in Primary Care Settings. [Google Scholar]
- Asarnow JR. Jaycox LH. Clarke G. Lewinsohn P. Hops H. Rohde P. Stress, Your Mood: A Manual. Los Angeles, CA: UCLA School of Medicine; 1999. [Google Scholar]
- Clarke GN. Lewinsohn PM. Hops H. Seeley JR. Adolescent Coping with Depression Course. Eugene, OR: Castalla Press; 1990. [Google Scholar]
- Kessler RC. Epidemiology of depression. In: Gotlib I, editor; Hammen CL, editor. Handbook of Depression. New York: Guildford Press; 2002. pp. 23–42. [Google Scholar]
- World Health Organization. Composite International Diagnostic Interview (CIDI): Core Version 2.1: Interviewer's Manual. Geneva, Switzerland: World Health Organization; 1997. [Google Scholar]
Cited by
Sorted by citations
Zuckerbrot, R. A., Cheung, A., Jensen, P. S., Stein, R. E. K., Laraque, D., GLAD-PC STEERING GROUP, Levitt, A., Birmaher, B., Campo, J., Clarke, G., et al. (2018) · Pediatrics · doi:10.1542/peds.2017-4081 · Cited by 446 · see citing works
Universal Mental Health Screening in Pediatric Primary Care: A Systematic Review
Wissow, L. S., Brown, J. D., Fothergill, K. E., Gadomski, A., Hacker, K. A., Salmon, P., & Zelkowitz, R. L. (2013) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2013.08.013 · Cited by 170 · see citing works
Lee‐Tauler, S. Y., Eun, J. D., Corbett, D., & Collins, P. Y. (2018) · Psychiatric Services · doi:10.1176/appi.ps.201700382 · Cited by 77 · see citing works
Forman‐Hoffman, V. L., Middleton, J. C., McKeeman, J. L., Stambaugh, L. F., Christian, R. B., Gaynes, B. N., Kane, H., Kahwati, L. C., Lohr, K. N., & Viswanathan, M. (2017) · Implementation Science · doi:10.1186/s13012-017-0626-4 · Cited by 68 · see citing works
Asarnow, J. R., & Miranda, J. M. (2014) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-032813-153742 · Cited by 56 · see citing works
Suicide in the pediatric population: screening, risk assessment and treatment
Cwik, M. F., O’Keefe, V. M., & Haroz, E. E. (2020) · International Review of Psychiatry · doi:10.1080/09540261.2019.1693351 · Cited by 54 · see citing works
Development and Piloting of a Brief Intervention for Suicidal American Indian Adolescents
Cwik (2016) · American Indian and Alaska Native Mental Health Research · doi:10.5820/aian.2301.2016.105 · Cited by 48 · see citing works
Rapp, A. M., Chavira, D. A., Sugar, C. A., & Asarnow, J. R. (2017) · Journal of Pediatric Psychology · doi:10.1093/jpepsy/jsx057 · Cited by 29 · see citing works
Collaborative and integrated care for adolescent depression
Kodish, I., Richardson, L., & Schlesinger, A. (2019) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/j.chc.2019.02.003 · Cited by 19 · see citing works
Asato, M. R., Doss, J. L., & Plioplys, S. (2015) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2015.03.033 · Cited by 19 · see citing works
McKowen, J. W., Tompson, M. C., Brown, T. A., & Asarnow, J. R. (2013) · Journal of Clinical Child & Adolescent Psychology · doi:10.1080/15374416.2012.759226 · Cited by 18 · see citing works
Long-Run Trends in Antidepressant Use Among Youths After the FDA Black Box Warning
Kafali, N., Progovac, A. M., Hou, S. S., & Cook, B. L. (2017) · Psychiatric Services · doi:10.1176/appi.ps.201700089 · Cited by 17 · see citing works
Appleton, R., Barnett, P., Clarke, C., Yang, J., Begum, S., Edbrooke-Childs, J. H., Emptage, I., Foye, U., Griffiths, J., Hanson, I., et al. (2025) · BMC Medicine · doi:10.1186/s12916-025-04438-8 · Cited by 16 · see citing works
Courtney, D., Cheung, A., Henderson, J. L., BENNETT, K. J., Wang, W., Chen, S., Battaglia, M., Strauss, J., Mitchell, R. H. B., Wang, K., et al. (2022) · JCPP Advances · doi:10.1002/jcv2.12083 · Cited by 15 · see citing works
Cook, B. L., Brown, J. D., Loder, S., & Wissow, L. (2014) · Journal of Immigrant and Minority Health · doi:10.1007/s10903-014-0010-2 · Cited by 15 · see citing works
The Psychopharmacology of Adolescent Depression
Emslie, G. J. (2012) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2012.2212 · Cited by 14 · see citing works
Using the Knowledge Base of Health Services Research to Redefine Health Care Systems
Brook, R. H., & Vaiana, M. E. (2015) · Journal of General Internal Medicine · doi:10.1007/s11606-015-3298-2 · Cited by 13 · see citing works
Measurement-Based Care in the Treatment of Adolescent Depression
Abright, A. R., & Grudnikoff, E. (2020) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/j.chc.2020.06.003 · Cited by 12 · see citing works
Evidence-based youth suicide prevention and intervention in pediatric primary care settings.
Ruch, D. A., Hughes, J. L., Bridge, J. A., & Fontanella, C. A. (2024) · Pediatric Clinics of North America · doi:10.1016/j.pcl.2024.07.017 · Cited by 10 · see citing works
Kodish, T., Lau, A. S., Belin, T. R., Berk, M. S., & Asarnow, J. R. (2022) · Psychiatric Services · doi:10.1176/appi.ps.20220129 · Cited by 10 · see citing works
A Systematic Review of External Validity in Pediatric Integrated Primary Care Trials
Callejo-Black, A., Wagner, D. V., Ramanujam, K., Manabat, A. J., Mastel, S. A., & Riley, A. R. (2020) · Journal of Pediatric Psychology · doi:10.1093/jpepsy/jsaa068 · Cited by 9 · see citing works
Mitchell, A. M., Davies, M. A., Cassesse, C. G., & Curran, R. (2013) · The Journal for Nurse Practitioners · doi:10.1016/j.nurpra.2013.08.012 · Cited by 9 · see citing works
Slater, H., AlZubi, Y., Rezaeizadeh, A., Hughes, J. L., Gorman, A., Mayes, T. L., Elmore, J. S., Storch, E. A., Wakefield, S. M., & Trivedi, M. H. (2024) · Child Psychiatry & Human Development · doi:10.1007/s10578-023-01653-3 · Cited by 5 · see citing works
Appleton, R., Barnett, P., Clarke, C., Yang, J., Begum, S., Edbrooke-Childs, J. H., Emptage, I., Foye, U., Griffiths, J., Hanson, I., et al. (2025) · medRxiv · doi:10.1101/2025.02.07.25321864 · Cited by 4 · see citing works
Ayvaci, E. R., Minhajuddin, A., Elmore, J. S., Yagnik, K., Jha, M. K., Emslie, G. J., Mayes, T. L., & Trivedi, M. H. (2024) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2023.0041 · Cited by 2 · see citing works
Pringsheim, T. M., Gaudet, L., Pillay, J., Hartling, L., Fletcher, J., Wilcox, G., Patten, S. B., & Martino, D. (2024) · PubMed Central · Cited by 2 · see citing works
Reetz, S., Clarke, G., Weersing, R., Amir, N., Dickerson, J. F., Lynch, F. L., Leo, M., Rawlings, A., Lee, M. H., & Gille, S. (2019) · BMC Psychiatry · doi:10.1186/s12888-019-2296-z · Cited by 3 · see citing works
Cohen, D., & Klodnick, V. V. (2024) · Oxford University Press eBooks · doi:10.1093/med/9780197617328.003.0004
- Authors
- Wells, K. B., Tang, L., Carlson, G. A., & Asarnow, J. R.
- Affiliations
- University of California, Los Angeles (US)
- Stony Brook University (US)
- Corresponding author
- Asarnow, Joan Rosenbaum
- Venue
- Journal of Child and Adolescent Psychopharmacology
- Publisher
- SAGE Publications
- Published
- 2012-02
- Volume
- 22
- Issue
- 1
- Pages
- 80-90
- ISSN
- 1044-5463 (ISSN-L)
- 1557-8992
- PMC
- PMC3281292
- OpenAlex
- W1994311202
- Cited by
- 28
- References
- 44
- Citations by year
- 2025: 2 · 2024: 5 · 2022: 2 · 2020: 3 · 2019: 2 · 2018: 2 · 2017: 3 · 2016: 1 · 2015: 2 · 2014: 2 · 2013: 3 · 2012: 1
- FWCI
- 3.85
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Journal of Child and Adolescent Psychopharmacology (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Kaiser Permanente
- University of Pittsburgh
- National Institutes of Health (5p30mh068639-05)
- Agency for Healthcare Research and Quality (HS09908)
- University of California, Los Angeles
- National Institute of Mental Health (P30MH082760, P30-MH068639)
- Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles
- Topics
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Keywords
- adolescent depression, primary care, antidepressants, cognitive behavioral therapy, quality improvement intervention, guideline adherence, severe depression, depressive disorders, Latino youth, provider education
- MeSH terms
- Adolescent, Algorithms, Antidepressive Agents, Major Depressive Disorder, Female, Follow-Up Studies, Humans, Male, Primary Health Care, Quality Assurance, Health Care, Severity of Illness Index, Cognitive Behavioral Therapy, Treatment Outcome, Practice Guidelines as Topic, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
