The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
mi RNA Profiling for Diagnosis and Prognosis of Human Cancer
Abstract
MicroRNAs (miRNAs) are a recently discovered class of small (approximately 18-24 nt) nucleic acids that negatively regulate gene expression. This novel class of molecules modulates a wide array of growth and differentiation processes in human cancers. High throughput analyses, utilizing the solid phase, array platform, or liquid phase, bead-based hybridization have variously demonstrated that miRNA expression was commonly dysregulated in human cancer. miRNA expression profiling has shown promise in defining malignant status in retrospective studies. Considerable disagreement remains with respect to the miRNA signature for a specific cancer cell type, which appears to depend largely on the analytical platform. Nonetheless, various internally controlled studies have successfully identified the histotype of tumors of unknown origin according to miRNA expression profile. The evaluation of miRNAs expression may also be of prognostic value, as best exemplified by the correlation of let-7 and mir-155 levels with disease survival in nonsmall cell lung cancer.
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Cites
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
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Prediction of Mammalian MicroRNA Targets
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Identification of Novel Genes Coding for Small Expressed RNAs
Lagos-Quintana, M., Rauhut, R., Lendeckel, W., & Tuschl, T. (2001) · Science · doi:10.1126/science.1064921 · Cited by 4,956
MicroRNA Gene Expression Deregulation in Human Breast Cancer
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An oligonucleotide microchip for genome-wide microRNA profiling in human and mouse tissues
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Cited by
MicroRNA: Biogenesis, Function and Role in Cancer
MacFarlane, L.-A., & R. Murphy, P. (2010) · Current Genomics · doi:10.2174/138920210793175895 · Cited by 1,584
miR-155 gene: A typical multifunctional microRNA
Faraoni, I., Antonetti, F. R., Cardone, J., & Bonmassar, E. (2009) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2009.02.013 · Cited by 815
Cross talk between microRNA and epigenetic regulation in adult neurogenesis
Szulwach, K. E., Li, X., Smrt, R. D., Li, Y., Luo, Y., Lin, L., Santistevan, N. J., Li, W., Zhao, X., & Jin, P. (2010) · Journal of Cell Biology · doi:10.1083/jcb.200908151 · Cited by 493
MicroRNA-155 Suppresses Activation-Induced Cytidine Deaminase-Mediated Myc-Igh Translocation
Dorsett, Y., McBride, K. M., Jankovic, M., Gazumyan, A., Thai, T.-H., Robbiani, D. F., Di Virgilio, M., San-Martin, B. R., Heidkamp, G., Schwickert, T. A., et al. (2008) · Immunity · doi:10.1016/j.immuni.2008.04.002 · Cited by 458
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Metadata
- Authors
- Jay, C., Nemunaitis, J., Chen, P., Fulgham, P., & Tong, A. W.
- Venue
- DNA and Cell Biology
- Publisher
- SAGE Publications
- Published
- 2007-05
- Volume
- 26
- Issue
- 5
- Pages
- 293-300
- ISSN
- 1044-5498 (ISSN-L)
- 1557-7430
- OpenAlex
- W2003463953
- Cited by
- 223
- References
- 8
- FWCI
- 7.82
- Type
- journal article
- Language
- en
- Open access
- closed
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- Jay, C., Nemunaitis, J., Chen, P., Fulgham, P., & Tong, A. W. (2007). mi RNA Profiling for Diagnosis and Prognosis of Human Cancer. DNA and Cell Biology. https://doi.org/10.1089/dna.2006.0554
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.