Equine interferons following exposure to equid herpesvirus-1 or -4.
Abstract
When 23 ponies were infected with equid herpesvirus-1 or -4 (EHV-1 or EHV-4), nasal shedding of interferon (IFN) correlated closely with the duration of viral excretion. Equine interferon (EqIFN) was detected in the serum only from animals infected with the EHV-1 virus, and here high levels correlated with clinical symptoms of locomotor disorder and indicated a poor prognosis. Low levels of IFN were detected in explanted mononuclear cells from ponies infected with either virus.
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Equine type 1 interferon has been detected in nasal secretions and serum of experimentally EHV-1-infected ponies during the first 2 weeks post-inoculation.
“Equine type 1 interferon (IFNα/β) has been detected in nasal secretions and serum of experimentally EHV-1-infected ponies the first 2 weeks post-inoculation (Edington et al., 1989; Chong and Duffus, 1992).”
From The Pathogenesis and Immune Evasive Mechanisms of Equine Herpesvirus Type 1 (2021) · cites this paper as Edington et al., 1989
Cites
Immune interferon: a pleiotropic lymphokine with multiple effects
Trinchieri, G., & PERUSSIA, B. (1985) · Immunology Today · doi:10.1016/0167-5699(85)90080-5 · Cited by 667 · see citing works
Endothelial cell infection and thrombosis in paralysis caused by equid herpesvirus-1: equine stroke.
Edington, N., Bridges, C. G., & Patel, J. R. (1986) · Archives of Virology · doi:10.1007/bf01314149 · Cited by 213 · see citing works
Self-citationLymphocyte Interferon Production and Transformation after Herpes Simplex Infections in Humans
Rasmussen, L. E., Jordan, G. W., Stevens, D. A., et al. (1974) · The Journal of Immunology · doi:10.4049/jimmunol.112.2.728 · Cited by 150 · see citing works
Variation in cellular tropism between isolates of equine herpesvirus-1 in foals.
Patel, J. R., Edington, N., & Mumford, J. A. (1982) · Archives of Virology · doi:10.1007/bf01320781 · Cited by 132 · see citing works
Self-citationInterferon, antibody, and other host factors in herpes zoster
Stevens, D. A., & Merigan, T. C. (1972) · Journal of Clinical Investigation · doi:10.1172/jci106910 · Cited by 107 · see citing works
Trials of an inactivated equid herpesvirus 1 vaccine: challenge with a subtype 1 virus
Burrows, R., Goodridge, D., & Denyer, M. (1984) · Veterinary Record · doi:10.1136/vr.114.15.369 · Cited by 107 · see citing works
Engler, H., Zawatzky, R., Goldbach, A., et al. (1981) · Journal of General Virology · doi:10.1099/0022-1317-55-1-25 · Cited by 88 · see citing works
Zawatzky, R., Hilfenhaus, J., Marcucci, F., et al. (1981) · Journal of General Virology · doi:10.1099/0022-1317-53-1-31 · Cited by 81 · see citing works
Todd, J. D., Volenec, F. J., & PATON, I. M. (1972) · Infection and Immunity · doi:10.1128/iai.5.5.699-706.1972 · Cited by 75 · see citing works
Different antiviral spectra of human macrophage interferon activities
Bell, D. M., Roberts, N. J., & Hall, C. B. (1983) · Nature · doi:10.1038/305319a0 · Cited by 40 · see citing works
Innate immunity during Equid herpesvirus 1 (EHV-1) infection.
BRIDGES, C. G., & Edington, N. (1986) · PubMed Central · Cited by 20 · see citing works
Self-citationShimizu, F., Satoh, J., Tada, M., & Kumagai, K. (1978) · Infection and Immunity · doi:10.1128/iai.22.3.752-757.1978 · Cited by 17 · see citing works
Further Investigations of Equine Interferons In Vitro
Edington, N., BRIDGES, C. G., & GRIFFITHS, L. (1989) · Journal of Interferon Research · doi:10.1089/jir.1989.9.385 · Cited by 6 · see citing works
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The equine immune response to equine herpesvirus-1: The virus and its vaccines
Kydd, J. H., Townsend, H. G. G., & Hannant, D. (2006) · Veterinary Immunology and Immunopathology · doi:10.1016/j.vetimm.2006.01.005 · Cited by 134 · see citing works
Gryspeerdt, A. C., Vandekerckhove, A. P., Garré, B., Barbé, F., Van de Walle, G. R., & Nauwynck, H. J. (2010) · Veterinary Microbiology · doi:10.1016/j.vetmic.2009.10.015 · Cited by 69 · see citing works
The Pathogenesis and Immune Evasive Mechanisms of Equine Herpesvirus Type 1
Laval, K., Poelaert, K. C. K., Van Cleemput, J., Zhao, J., Vandekerckhove, A. P., Gryspeerdt, A. C., Garré, B., van der Meulen, K., Baghi, H. B., Dubale, H. N., et al. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.662686 · Cited by 54 · see citing works
Holz, C. L., Nelli, R. K., Wilson, M. E., Zarski, L. M., Azab, W., Baumgardner, R., Osterrieder, N., Pease, A., Zhang, L., Hession, S., et al. (2017) · Journal of General Virology · doi:10.1099/jgv.0.000773 · Cited by 34 · see citing works
SMITH, D., HAMBLIN, A., & EDINGTON, N. (2002) · Clinical and Experimental Immunology · doi:10.1046/j.1365-2249.2002.01463.x · Cited by 30 · see citing works
Self-citationEquine herpesvirus-1 suppresses type-I interferon induction in equine endothelial cells.
Sarkar, S., Balasuriya, U. B. R., Horohov, D. W., & Chambers, T. M. (2015) · Veterinary Immunology and Immunopathology · doi:10.1016/j.vetimm.2015.07.015 · Cited by 22 · see citing works
Abortigenic but not neurotropic equine Herpes Virus 1 modulates the interferon antiviral defense.
Poelaert, K. C. K., Van Cleemput, J., Laval, K., Favoreel, H. W., Soboll Hussey, G., Maes, R. K., & Nauwynck, H. J. (2018) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2018.00312 · Cited by 19 · see citing works
Oladunni, F. S., Sarkar, S., Reedy, S., Balasuriya, U. B. R., Horohov, D. W., & Chambers, T. M. (2019) · Journal of Virology · doi:10.1128/jvi.01342-19 · Cited by 18 · see citing works
- Authors
- EDINGTON, N., BRIDGES, C. G., & GRIFFITHS, L.
- Affiliations
- University of London (GB)
- Venue
- Journal of Interferon Research
- Publisher
- SAGE Publications
- Published
- 1989-08
- Volume
- 9
- Issue
- 4
- Pages
- 389-392
- ISSN
- 0197-8357 (ISSN-L)
- OpenAlex
- W2322602766
- Cited by
- 24
- References
- 13
- Citations by year
- 2024: 3 · 2023: 1 · 2022: 1 · 2021: 1 · 2020: 1 · 2019: 1 · 2018: 2 · 2017: 1 · 2015: 2 · 2014: 1 · 2013: 2
- FWCI
- 0.16
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Interferon Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › interferon and immune responses
- Health Sciences › Medicine › Epidemiology › Herpesvirus Infections and Treatments
- Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Animal Virus Infections Studies
- Keywords
- equine herpesvirus 1, nasal shedding, viral excretion, serum interferon levels, mononuclear cells, prognosis, ponies
- MeSH terms
- Animals, Herpesvirus 1, Equid, Female, Herpesviridae Infections, Horse Diseases, Horses, Interferons, Viremia
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