The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.
Sex and Gender Differences in Alzheimer's Disease: Recommendations for Future Research
Abstract
Alzheimer's disease (AD) disproportionately affects women in both prevalence and severity; however, the biologic mechanisms underlying these sex differences are not fully understood. Sex differences in the brain, such as in brain anatomy, age-related declines in brain volume, and brain glucose metabolism, have been documented and may be important in understanding AD etiology. The full impact of sex as a basic biologic variable on this neurodegenerative disease remains elusive. To address the evidence for sex differences in AD, the Society for Women's Health Research (SWHR) convened an interdisciplinary roundtable of experts from academia, clinical medicine, industry, and the government to discuss the state-of-the-science in sex and gender differences in AD. Roundtable participants were asked to address gaps in our knowledge and identify specific sex-based research questions for future areas of study.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“It is unclear whether genetic risk operates differently in women and men in the development of, or susceptibility to, Alzheimer's pathology.”
From 2024 Alzheimer's disease facts and figures (2024) · cites this paper as [310]
Citations
Cites
Kessler, R. (1993) · Journal of Affective Disorders · doi:10.1016/0165-0327(93)90026-g · Cited by 2,207 · cited 1×
“Women have higher rates of depression and anxiety, and these are emerging as risk factors for AD.(22) The role of hormone replacement therapy (HRT) is still a confused issue, and roundtable experts discussed research that supports improved cognitive function with HRT when given at early but not late stages of the meno…”
Prevalence of Dementia in the United States: The Aging, Demographics, and Memory Study
Plassman, B. L., Langa, K. M., Fisher, G. G., Heeringa, S. G., Weir, D. R., Ofstedal, M. B., Burke, J. R., Hurd, M. D., Potter, G. G., Rodgers, W. L., et al. (2007) · Neuroepidemiology · doi:10.1159/000109998 · Cited by 1,932
Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database
Bertram, L., McQueen, M. B., Mullin, K., Blacker, D., & Tanzi, R. E. (2007) · Nature Genetics · doi:10.1038/ng1934 · Cited by 1,857
Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP
Lewis, J., Dickson, D. W., Lin, W.-L., Chisholm, L., Corral, A., Jones, G., Yen, S.-H., Sahara, N., Skipper, L., Yager, D., et al. (2001) · Science · doi:10.1126/science.1058189 · Cited by 1,611
Alzheimer’s Disease: The Challenge of the Second Century
Holtzman, D. M., Morris, J. C., & Goate, A. M. (2011) · Science Translational Medicine · doi:10.1126/scitranslmed.3002369 · Cited by 1,424
Seshadri, S. S., Beiser, A., Kelly‐Hayes, M., Kase, C. S., Au, R., Kannel, W. B., & Wolf, P. A. (2006) · Stroke · doi:10.1161/01.str.0000199613.38911.b2 · Cited by 711
Gender differences in the incidence of AD and vascular dementia: The EURODEM Studies
Andersen, K., Launer, L. J., Dewey, M. E., Letenneur, L., Ott, A., Copeland, J. R. M., Dartigues, J.-F., Kragh–Sorensen, P., Baldereschi, M., Brayne, C., et al. (1999) · Neurology · doi:10.1212/wnl.53.9.1992 · Cited by 650
Caring for a relative with dementia: family caregiver burden
Papastavrou, E., Kalokerinou, A., Papacostas, S. S., Tsangari, H., & Sourtzi, P. (2007) · Journal of Advanced Nursing · doi:10.1111/j.1365-2648.2007.04250.x · Cited by 540
Viña, J., & Lloret, A. (2010) · Journal of Alzheimer's Disease · doi:10.3233/jad-2010-100501 · Cited by 447
Exercise Time: Gender Differences in the Effects of Marriage, Parenthood, and Employment
Nomaguchi, K. M., & Bianchi, S. M. (2004) · Journal of Marriage and the Family · doi:10.1111/j.1741-3737.2004.00029.x · Cited by 322
Rocca, W. A., Grossardt, B. R., & Shuster, L. T. (2011) · Brain Research · doi:10.1016/j.brainres.2010.10.031 · Cited by 283
Postmenopausal hormone therapy and Alzheimer's disease risk: interaction with age
Henderson, V. W. (2004) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.2003.024927 · Cited by 265
The role of aromatization in testosterone supplementation: Effects on cognition in older men
Cherrier, M. M., Matsumoto, A. M., Amory, J. K., Ahmed, S., Bremner, W., Peskind, E. R., Raskind, M. A., Johnson, M., & Craft, S. (2005) · Neurology · doi:10.1212/01.wnl.0000149639.25136.ca · Cited by 226
Taking ‘Women's Work’ ‘Like a Man’: Husbands' Experiences of Care Work
Calasanti, T., & King, N. (2007) · The Gerontologist · doi:10.1093/geront/47.4.516 · Cited by 210
Hysterectomy, Oophorectomy and Risk of Dementia: A Nationwide Historical Cohort Study
Phung, T. K. T., Waltoft, B. L., Laursen, T. M., Settnes, A., Kessing, L. V., Mortensen, P. B., & Waldemar, G. (2010) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000314681 · Cited by 204
Katz, S. J. (2000) · JAMA · doi:10.1001/jama.284.23.3022 · Cited by 192
Mosconi, L., Mistur, R., Switalski, R., Brys, M., Glodzik, L., Rich, K., Pirraglia, E., Tsui, W., De Santi, S., & de Leon, M. J. (2009) · Neurology · doi:10.1212/01.wnl.0000333247.51383.43 · Cited by 188
Dementia and Alzheimer Disease Incidence Rates Do Not Vary by Sex in Rochester, Minn
Edland, S. D., Rocca, W. A., Petersen, R. C., Cha, R. H., & Kokmen, E. (2002) · Archives of Neurology · doi:10.1001/archneur.59.10.1589 · Cited by 184
Cognitive deficits of men and women with Alzheimer's disease
Henderson, V. W., & Buckwalter, J. G. (1994) · Neurology · doi:10.1212/wnl.44.1.90 · Cited by 170
Mapping the connections between education and dementia
McDowell, I., Xi, G., Lindsay, J., & Tierney, M. (2007) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/13803390600582420 · Cited by 157
Rosario, E. R., Carroll, J. C., Oddo, S., LaFerla, F. M., & Pike, C. J. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.2514-06.2006 · Cited by 154
Surgical versus natural menopause: cognitive issues
Henderson, V. W., & Sherwin, B. B. (2007) · Menopause · doi:10.1097/gme.0b013e31803df49c · Cited by 154
Rosario, E. R., Carroll, J. C., & Pike, C. J. (2010) · Brain Research · doi:10.1016/j.brainres.2010.08.068 · Cited by 133
Hormone therapy and cognitive function
Maki, P. M., & Sundermann, E. E. (2009) · Human Reproduction Update · doi:10.1093/humupd/dmp022 · Cited by 117
Men caring for wives or partners with dementia: Masculinity, strain and gain
Baker, K. L., Robertson, N., & Connelly, D. (2010) · Aging & Mental Health · doi:10.1080/13607860903228788 · Cited by 115
APOE-4 Genotype and Neurophysiological Vulnerability to Alzheimer's and Cognitive Aging
Bookheimer, S. Y., & Burggren, A. C. (2009) · Annual Review of Clinical Psychology · doi:10.1146/annurev.clinpsy.032408.153625 · Cited by 108
Cardiorespiratory Fitness as a Predictor of Dementia Mortality in Men and Women
Liu, R., Sui, X., Laditka, J. N., Church, T. S., Colabianchi, N., Hussey, J., & Blair, S. N. (2011) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e31822cf717 · Cited by 94
Systemic inflammation and Alzheimer's disease
Holmes, C., & Butchart, J. (2011) · Biochemical Society Transactions · doi:10.1042/bst0390898 · Cited by 92
Perneczky, R., Wagenpfeil, S., Lunetta, K. L., Cupples, L. A., Green, R. C., DeCarli, C. S., Farrer, L. A., & Kurz, A. (2009) · Journal of Alzheimer s Disease · doi:10.3233/jad-2009-1117 · Cited by 49
Behavioral consequences of ovarian atrophy and estrogen replacement in the APPswe mouse
Golub, M. S., Germann, S. L., Mercer, M., Gordon, M. N., Morgan, D., Mayer, L. P., & Hoyer, P. B. (2007) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2007.03.015 · Cited by 36
Feld, S., Dunkle, R. E., Schroepfer, T. A., & Shen, H. (2010) · Research on Aging · doi:10.1177/0164027510361461 · Cited by 36
Fallah, N., Mitnitski, A., Middleton, L. E., & Rockwood, K. J. (2009) · Neuroepidemiology · doi:10.1159/000211953 · Cited by 24
Marital Implications of Parent-Adult Child Coresidence: A Longitudinal View
Ward, R. A., & Spitze, G. D. (2004) · The Journals of Gerontology Series B · doi:10.1093/geronb/59.1.s2 · Cited by 19
Devi, S., Veerraju, P., & Rao, S. R. (1994) · Human Heredity · doi:10.1159/000154197 · Cited by 6
A model of caregiver's willingness to provide care.
Miller, M., & Eisdorfer, C. (1989) · PubMed · Cited by 3
Flagged first, then by citations
Research works printed but not linked: 1
- Miller M, 1989, Caring, 8, 10
Cited by
Sorted by citations
2016 Alzheimer's disease facts and figures
Alzheimer's Association (2016) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2016.03.001 · Cited by 5,069
2023 Alzheimer's disease facts and figures
(2023) · Alzheimer's & Dementia · doi:10.1002/alz.13016 · Cited by 3,212
2024 Alzheimer's disease facts and figures
(2024) · Alzheimer's & Dementia · doi:10.1002/alz.13809 · Cited by 2,536
2019 Alzheimer’s disease facts and figures.
Alzheimer's Association (2019) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2019.01.010 · Cited by 2,461
2020 Alzheimer's disease facts and figures
(2020) · Alzheimer's & Dementia · doi:10.1002/alz.12068 · Cited by 2,353
Metadata
- Authors
- Carter, C. L., Resnick, E. M., Mallampalli, M., & Kalbarczyk, A.
- Affiliations
- Society for Women's Health Research (US)
- Corresponding author
- Carter, Christine L.
- Venue
- Journal of Women's Health
- Publisher
- SAGE Publications
- Published
- 2012-10
- Volume
- 21
- Issue
- 10
- Pages
- 1018-1023
- ISSN
- 1059-7115 (ISSN-L)
- 1540-9996
- 1931-843X
- OpenAlex
- W2160236532
- Cited by
- 231
- References
- 35
- Citations by year
- 2026: 6 · 2025: 17 · 2024: 22 · 2023: 19 · 2022: 20 · 2021: 19 · 2020: 21 · 2019: 23 · 2018: 18 · 2017: 12 · 2016: 23 · 2015: 11 · 2014: 10 · 2013: 8 · 2012: 1
- FWCI
- 6.82
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Women s Health (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Sex and Gender in Healthcare
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Keywords
- Alzheimer's disease, sex differences, gender differences, women's health, neuroanatomy, brain glucose metabolism, neurodegeneration, research priorities, sex as a biological variable
- MeSH terms
- Alzheimer Disease, Congresses as Topic, Female, Humans, Sex Characteristics, Sex Factors, Societies, Medical, Women's Health, Biomedical Research
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
