The DOI matches its Crossref record; 130 of the 130 references it cites were found in a registry or an index.
Neuronal Apoptosis After CNS Injury: The Roles of Glutamate and Calcium
Abstract
While a role has been well established for excitotoxic necrosis in the pathogenesis of traumatic or ischemic damage to the CNS, accumulating evidence now suggests that apoptosis may also be a prominent contributor. In this review we focus on the role of glutamate and attendant intracellular calcium influx in triggering or modifying excitotoxic necrosis and apoptosis, raising the possibility that calcium influx may affect these two death pathways in opposite directions. Incorporating consideration of both pathways will probably be needed to develop the most effective neuroprotective treatments for CNS injury.
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Cites
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Cited by
A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia
Borsello, T., Clarke, P. G. H., Hirt, L., Vercelli, A., Repici, M., Schorderet, D. F., Bogousslavsky, J., & Bonny, C. (2003) · Nature Medicine · doi:10.1038/nm911 · Cited by 658
Degenerative and regenerative mechanisms governing spinal cord injury
Profyris, C., Cheema, S. S., Zang, D., Azari, M. F., Boyle, K., & Petratos, S. (2004) · Neurobiology of Disease · doi:10.1016/j.nbd.2003.11.015 · Cited by 458
Chapter 4 Cell death in models of spinal cord injury
Beattie, M. S., Hermann, G. E., Rogers, R. C., & Bresnahan, J. C. (2002) · Progress in Brain Research · doi:10.1016/s0079-6123(02)37006-7 · Cited by 453
Beyond the role of glutamate as a neurotransmitter
Nedergaard, M., Takano, T., & Hansen, A. J. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn916 · Cited by 450
Olivares, D., K. Deshpande, V., Shi, Y., K. Lahiri, D., H. Greig, N., T. Rogers, J., & Huang, X. (2012) · Current Alzheimer Research · doi:10.2174/156720512801322564 · Cited by 407
Metadata
- Authors
- ZIPFEL, G. J., BABCOCK, D. J., LEE, J.-M., & CHOI, D. W.
- Venue
- Journal of Neurotrauma
- Publisher
- SAGE Publications
- Published
- 2000-10
- Volume
- 17
- Issue
- 10
- Pages
- 857-869
- ISSN
- 0897-7151 (ISSN-L)
- 1557-9042
- OpenAlex
- W1967544492
- Cited by
- 281
- References
- 130
- FWCI
- 5.52
- Type
- journal article
- Language
- en
- Open access
- closed
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- ZIPFEL, G. J., BABCOCK, D. J., LEE, J.-M., & CHOI, D. W. (2000). Neuronal Apoptosis After CNS Injury: The Roles of Glutamate and Calcium. Journal of Neurotrauma. https://doi.org/10.1089/neu.2000.17.857
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
