The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Mechanisms of Working Memory Dysfunction after Mild and Moderate TBI: Evidence from Functional MRI and Neurogenetics
Abstract
Cognitive complaints are a frequent source of distress and disability after mild and moderate traumatic brain injury (TBI). While there are deficits in several cognitive domains, many aspects of these complaints and deficits suggest that problems in working memory (WM) play an important role. Functional imaging studies in healthy individuals have outlined the neural substrate of WM and have shown that regions important in WM circuitry overlap with regions commonly vulnerable to damage in TBI. Use of functional MRI (fMRI) in individuals with mild and moderate TBI suggests that they can have problems in the activation and allocation of WM, and several lines of evidence suggest that subtle alterations in central catecholaminergic sensitivity may underlie these problems. We review the evidence from fMRI and neurogenetic studies that support the role of catecholaminergic dysregulation in the etiology of WM complaints and deficits after mild and moderate TBI.
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Self-citationMotor and cognitive deficits in apolipoprotein E-deficient mice after closed head injury
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Cited by
Exploring the convergence of posttraumatic stress disorder and mild traumatic brain injury
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Self-citationNeuropathology of mild traumatic brain injury: relationship to neuroimaging findings
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Metadata
- Authors
- McAllister, T. W., Flashman, L. A., McDonald, B. C., & Saykin, A. J.
- Venue
- Journal of Neurotrauma
- Publisher
- SAGE Publications
- Published
- 2006-10
- Volume
- 23
- Issue
- 10
- Pages
- 1450-1467
- ISSN
- 0897-7151 (ISSN-L)
- 1557-9042
- OpenAlex
- W2054642828
- Cited by
- 272
- References
- 9
- FWCI
- 6.64
- Type
- journal article
- Language
- en
- Open access
- closed
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