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Cited by 341

The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.

Epidemiology of Chronic Effects of Traumatic Brain Injury

Open access
Haarbauer-Krupa, Juliet, Pugh, Mary Jo, Prager, Eric M, Harmon, Nicole, Wolfe, Jessica, Yaffe, Kristine·2021·Journal of Neurotrauma

Abstract

Although many patients diagnosed with traumatic brain injury (TBI), particularly mild TBI, recover from their symptoms within a few weeks, a small but meaningful subset experience symptoms that persist for months or years after injury and significantly impact quality of life for the person and their family. Factors associated with an increased likelihood of negative TBI outcomes include not only characteristics of the injury and injury mechanism, but also the person's age, pre-injury status, comorbid conditions, environment, and propensity for resilience. In this article, as part of the Brain Trauma Blueprint: TBI State of the Science framework, we examine the epidemiology of long-term outcomes of TBI, including incidence, prevalence, and risk factors. We identify the need for increased longitudinal, global, standardized, and validated assessments on incidence, recovery, and treatments, as well as standardized assessments of the influence of genetics, race, ethnicity, sex, and environment on TBI outcomes. By identifying how epidemiological factors contribute to TBI outcomes in different groups of persons and potentially impact differential disease progression, we can guide investigators and clinicians toward more-precise patient diagnosis, along with tailored management, and improve clinical trial designs, data evaluation, and patient selection criteria.

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Crossref · 10.1089/neu.2021.0062

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Metadata

Authors
Haarbauer-Krupa, J., Pugh, M. J., Prager, E. M., Harmon, N., Wolfe, J., & Yaffe, K.
Venue
Journal of Neurotrauma
Published
2021-12-01
Volume
38
Issue
23
Pages
3235-3247
ISSN
  • 0897-7151 (ISSN-L)
  • 1557-9042
OpenAlex
W3157802181
Cited by
341
References
19
FWCI
24.51
Type
journal article
Language
en
Open access
hybrid

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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