The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Epidemiology of Chronic Effects of Traumatic Brain Injury
Open accessAbstract
Although many patients diagnosed with traumatic brain injury (TBI), particularly mild TBI, recover from their symptoms within a few weeks, a small but meaningful subset experience symptoms that persist for months or years after injury and significantly impact quality of life for the person and their family. Factors associated with an increased likelihood of negative TBI outcomes include not only characteristics of the injury and injury mechanism, but also the person's age, pre-injury status, comorbid conditions, environment, and propensity for resilience. In this article, as part of the Brain Trauma Blueprint: TBI State of the Science framework, we examine the epidemiology of long-term outcomes of TBI, including incidence, prevalence, and risk factors. We identify the need for increased longitudinal, global, standardized, and validated assessments on incidence, recovery, and treatments, as well as standardized assessments of the influence of genetics, race, ethnicity, sex, and environment on TBI outcomes. By identifying how epidemiological factors contribute to TBI outcomes in different groups of persons and potentially impact differential disease progression, we can guide investigators and clinicians toward more-precise patient diagnosis, along with tailored management, and improve clinical trial designs, data evaluation, and patient selection criteria.
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Cites
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“56 The factors contributing to delayed or incomplete recovery include comorbid psychiatric disorders, age at time of injury (see more below), abnormal acute neuroimaging, expectation of poor outcomes, and repetitive injuries (see an earlier work 110 for additional details).”
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Self-citationDepression and cognitive complaints following mild traumatic brain injury
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“90 96 Biological and environmental circumstances are diffi-cult to separate as risk factors for TBI outcomes.”
Population based study on patients with traumatic brain injury suggests increased risk of dementia
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Cited by
Serum/glucocorticoid regulated kinase 1 (SGK1) in neurological disorders: pain or gain
Howard, P. G., Zou, P., Zhang, Y., Huang, F., Tesic, V., Wu, C. Y.-C., & Lee, R. H.-C. (2024) · Experimental Neurology · doi:10.1016/j.expneurol.2024.114973 · Cited by 13
Metadata
- Authors
- Haarbauer-Krupa, J., Pugh, M. J., Prager, E. M., Harmon, N., Wolfe, J., & Yaffe, K.
- Venue
- Journal of Neurotrauma
- Publisher
- SAGE Publications
- Published
- 2021-12-01
- Volume
- 38
- Issue
- 23
- Pages
- 3235-3247
- ISSN
- 0897-7151 (ISSN-L)
- 1557-9042
- OpenAlex
- W3157802181
- Cited by
- 341
- References
- 19
- FWCI
- 24.51
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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